Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization
Casci, Ian, Krishnamurthy, Karthik, Kour, Sukhleen, Tripathy, Vadreenath, Ramesh, Nandini, Anderson, Eric N, Marrone, Lara, Grant, Rogan A, Oliver, Stacie, Gochenaur, Lauren, Patel, Krishani, Sterneckert, Jared, Gleixner, Amanda M, Donnelly, Christopher J, Ruepp, Marc-David, Sini, Antonella M, Zuccaro, Emanuela, Pennuto, Maria, Pasinelli, Piera, Pandey, Udai Bhan
Published in Nature communications (06.12.2019)
Published in Nature communications (06.12.2019)
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Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo
Scaramuzzino, Chiara, Monaghan, John, Milioto, Carmelo, Lanson, Jr, Nicholas A, Maltare, Astha, Aggarwal, Tanya, Casci, Ian, Fackelmayer, Frank O, Pennuto, Maria, Pandey, Udai Bhan
Published in PloS one (19.04.2013)
Published in PloS one (19.04.2013)
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Protein arginine methyltransferase 6 enhances polyglutamine-expanded androgen receptor function and toxicity in spinal and bulbar muscular atrophy
Scaramuzzino, Chiara, Casci, Ian, Parodi, Sara, Lievens, Patricia M J, Polanco, Maria J, Milioto, Carmelo, Chivet, Mathilde, Monaghan, John, Mishra, Ashutosh, Badders, Nisha, Aggarwal, Tanya, Grunseich, Christopher, Sambataro, Fabio, Basso, Manuela, Fackelmayer, Frank O, Taylor, J Paul, Pandey, Udai Bhan, Pennuto, Maria
Published in Neuron (Cambridge, Mass.) (07.01.2015)
Published in Neuron (Cambridge, Mass.) (07.01.2015)
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Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy
Marrone, Lara, Poser, Ina, Casci, Ian, Japtok, Julia, Reinhardt, Peter, Janosch, Antje, Andree, Cordula, Lee, Hyun O., Moebius, Claudia, Koerner, Ellen, Reinhardt, Lydia, Cicardi, Maria Elena, Hackmann, Karl, Klink, Barbara, Poletti, Angelo, Alberti, Simon, Bickle, Marc, Hermann, Andreas, Pandey, Udai Bhan, Hyman, Anthony A., Sterneckert, Jared L.
Published in Stem cell reports (13.02.2018)
Published in Stem cell reports (13.02.2018)
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RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations
Daigle, J Gavin, Lanson, Jr, Nicholas A, Smith, Rebecca B, Casci, Ian, Maltare, Astha, Monaghan, John, Nichols, Charles D, Kryndushkin, Dmitri, Shewmaker, Frank, Pandey, Udai Bhan
Published in Human molecular genetics (15.03.2013)
Published in Human molecular genetics (15.03.2013)
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Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity
Daigle, J. Gavin, Krishnamurthy, Karthik, Ramesh, Nandini, Casci, Ian, Monaghan, John, McAvoy, Kevin, Godfrey, Earl W., Daniel, Dianne C., Johnson, Edward M., Monahan, Zachary, Shewmaker, Frank, Pasinelli, Piera, Pandey, Udai Bhan
Published in Acta neuropathologica (01.04.2016)
Published in Acta neuropathologica (01.04.2016)
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Copy number variants of schizophrenia susceptibility loci are associated with a spectrum of speech and developmental delays and behavior problems
Sahoo, Trilochan, Theisen, Aaron, Rosenfeld, Jill A, Lamb, Allen N, Ravnan, J Britt, Schultz, Roger A, Torchia, Beth S, Neill, Nicholas, Casci, Ian, Bejjani, Bassem A, Shaffer, Lisa G
Published in Genetics in medicine (01.10.2011)
Published in Genetics in medicine (01.10.2011)
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Identifying dominant modifiers of mutant FUS toxicity in vivo
Daigle, J Gavin, Lanson, Nicholas A, Casci, Ian, Monaghan, John, Nichols, Charles, Kryndushkin, Dimitri, Shewmaker, Frank, Pandey, Udai
Published in Molecular neurodegeneration (13.09.2013)
Published in Molecular neurodegeneration (13.09.2013)
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Protein Arginine Methyltransferase 1 and 8 Interact with FUS to Modify Its Sub-Cellular Distribution and Toxicity In Vitro and In Vivo. e61576
Scaramuzzino, Chiara, Monaghan, John, Milioto, Carmelo, Lanson, Nicholas A, Maltare, Astha, Aggarwal, Tanya, Casci, Ian, Fackelmayer, Frank O, Pennuto, Maria, Pandey, Udai Bhan
Published in PloS one (01.04.2013)
Published in PloS one (01.04.2013)
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