SARS‐CoV‐2 infects an upper airway model derived from induced pluripotent stem cells
Djidrovski, Ivo, Georgiou, Maria, Hughes, Grant L., Patterson, Edward I., Casas‐Sanchez, Aitor, Pennington, Shaun H., Biagini, Giancarlo A., Moya‐Molina, Marina, Bor, Jelle, Smit, Martine J., Chung, Git, Lako, Majlinda, Armstrong, Lyle
Published in Stem cells (Dayton, Ohio) (01.10.2021)
Published in Stem cells (Dayton, Ohio) (01.10.2021)
Get full text
Journal Article
Web Resource
Methods of Inactivation of SARS-CoV-2 for Downstream Biological Assays
Patterson, Edward I, Prince, Tessa, Anderson, Enyia R, Casas-Sanchez, Aitor, Smith, Shirley L, Cansado-Utrilla, Cintia, Solomon, Tom, Griffiths, Michael J, Acosta-Serrano, Álvaro, Turtle, Lance, Hughes, Grant L
Published in The Journal of Infectious Diseases (15.08.2020)
Published in The Journal of Infectious Diseases (15.08.2020)
Get full text
Journal Article
Web Resource
Proline Metabolism is Essential for Trypanosoma brucei brucei Survival in the Tsetse Vector
Mantilla, Brian S, Marchese, Letícia, Casas-Sánchez, Aitor, Dyer, Naomi A, Ejeh, Nicholas, Biran, Marc, Bringaud, Frédéric, Lehane, Michael J, Acosta-Serrano, Alvaro, Silber, Ariel M
Published in PLoS pathogens (23.01.2017)
Published in PLoS pathogens (23.01.2017)
Get full text
Journal Article
Inhibition of Protein N- Glycosylation Blocks SARS-CoV-2 Infection
Casas-Sanchez, Aitor, Romero-Ramirez, Alessandra, Hargreaves, Eleanor, Ellis, Cameron C, Grajeda, Brian I, Estevao, Igor L, Patterson, Edward I, Hughes, Grant L, Almeida, Igor C, Zech, Tobias, Acosta-Serrano, Álvaro
Published in mBio (15.02.2022)
Published in mBio (15.02.2022)
Get full text
Journal Article
Oxidative Phosphorylation Is Required for Powering Motility and Development of the Sleeping Sickness Parasite Trypanosoma brucei in the Tsetse Fly Vector
Dewar, Caroline E, Casas-Sanchez, Aitor, Dieme, Constentin, Crouzols, Aline, Haines, Lee R, Acosta-Serrano, Álvaro, Rotureau, Brice, Schnaufer, Achim
Published in mBio (22.02.2022)
Published in mBio (22.02.2022)
Get full text
Journal Article
Association of Phlebotomus guggisbergi with Leishmania major and Leishmania tropica in a complex transmission setting for cutaneous leishmaniasis in Gilgil, Nakuru county, Kenya
Owino, Barrack O, Matoke-Muhia, Damaris, Alraey, Yasser, Mwangi, Jackline Milkah, Ingonga, Johnstone M, Ngumbi, Philip M, Casas-Sanchez, Aitor, Acosta-Serrano, Alvaro, Masiga, Daniel K
Published in PLoS neglected tropical diseases (01.10.2019)
Published in PLoS neglected tropical diseases (01.10.2019)
Get full text
Journal Article
Trypanosoma brucei colonizes the tsetse gut via an immature peritrophic matrix in the proventriculus
Rose, Clair, Casas-Sánchez, Aitor, Dyer, Naomi A., Solórzano, Carla, Beckett, Alison J., Middlehurst, Ben, Marcello, Marco, Haines, Lee R., Lisack, Jaime, Engstler, Markus, Lehane, Michael J., Prior, Ian A., Acosta-Serrano, Álvaro
Published in Nature microbiology (01.07.2020)
Published in Nature microbiology (01.07.2020)
Get full text
Journal Article
Vivaxin genes encode highly immunogenic, non-variant antigens on the Trypanosoma vivax cell-surface
Romero-Ramirez, Alessandra, Casas-Sánchez, Aitor, Autheman, Delphine, Duffy, Craig W, Brandt, Cordelia, Clare, Simon, Harcourt, Katherine, André, Marcos Rogério, de Almeida Castilho Neto, Kayo José Garcia, Teixeira, Marta M. G, Machado, Rosangela Zacharias, Coombes, Janine, Flynn, Robin J, Wright, Gavin J, Jackson, Andrew P
Published in PLoS neglected tropical diseases (21.09.2022)
Published in PLoS neglected tropical diseases (21.09.2022)
Get full text
Journal Article
Old World cutaneous leishmaniasis treatment response varies depending on parasite species, geographical location and development of secondary infection
Al-Salem, Waleed S, Solórzano, Carla, Weedall, Gareth D, Dyer, Naomi A, Kelly-Hope, Louise, Casas-Sánchez, Aitor, Alraey, Yasser, Alyamani, Essam J, Halliday, Alice, Balghonaim, Salah M, Alsohibany, Khalid S, Alzeyadi, Zeyad, Alzahrani, Mohamed H, Al-Shahrani, Ali M, Assiri, Abdullah M, Memish, Ziad, Acosta-Serrano, Álvaro
Published in Parasites & vectors (02.05.2019)
Published in Parasites & vectors (02.05.2019)
Get full text
Journal Article
Variant antigen repertoires in Trypanosoma congolense populations and experimental infections can be profiled from deep sequence data using universal protein motifs
Silva Pereira, Sara, Casas-Sánchez, Aitor, Haines, Lee R, Ogugo, Moses, Absolomon, Kihara, Sanders, Mandy, Kemp, Steve, Acosta-Serrano, Álvaro, Noyes, Harry, Berriman, Matthew, Jackson, Andrew P
Published in Genome research (01.09.2018)
Published in Genome research (01.09.2018)
Get full text
Journal Article
Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis
Sterkel, Marcos, Haines, Lee R, Casas-Sánchez, Aitor, Owino Adung'a, Vincent, Vionette-Amaral, Raquel J, Quek, Shannon, Rose, Clair, Silva Dos Santos, Mariana, García Escude, Natalia, Ismail, Hanafy M, Paine, Mark I, Barribeau, Seth M, Wagstaff, Simon, MacRae, James I, Masiga, Daniel, Yakob, Laith, Oliveira, Pedro L, Acosta-Serrano, Álvaro
Published in PLoS biology (26.01.2021)
Published in PLoS biology (26.01.2021)
Get full text
Journal Article
The Trypanosoma brucei MISP family of invariant proteins is co-expressed with BARP as triple helical bundle structures on the surface of salivary gland forms, but is dispensable for parasite development within the tsetse vector
Casas-Sanchez, Aitor, Ramaswamy, Raghavendran, Perally, Samïrah, Haines, Lee R, Rose, Clair, Aguilera-Flores, Marcela, Portillo, Susana, Verbeelen, Margot, Hussain, Shahid, Smithson, Laura, Yunta, Cristina, Lehane, Michael J, Vaughan, Sue, van den Abbeele, Jan, Almeida, Igor C, Boulanger, Martin J, Acosta-Serrano, Álvaro
Published in PLoS pathogens (01.03.2023)
Published in PLoS pathogens (01.03.2023)
Get full text
Journal Article
Use it or lose it: The function of mitochondrial DNA in trypanosomes
Dewar, Caroline, Cooper, Sinclair, MacGregor, Paula, Casas-Sanchez, Aitor, Matthews, Keith, Savill, Nick, Acosta-Serrano, Alvaro, Schnaufer, Achim
Published in Biochimica et biophysica acta. Bioenergetics (01.08.2016)
Published in Biochimica et biophysica acta. Bioenergetics (01.08.2016)
Get full text
Journal Article
Characterization of a novel glycosylated glutathione transferase of Onchocerca ochengi , closest relative of the human river blindness parasite
Rose, Clair, Praulins, Giorgio, Armstrong, Stuart D, Casas-Sanchez, Aitor, Davis, Jem, Molyneux, Gemma, Yunta, Cristina, Stead, Zenaida, Prescott, Mark, Perally, Samirah, Rutter, Anne, Makepeace, Benjamin L, La Course, E James, Acosta-Serrano, Alvaro
Published in Parasitology (01.12.2019)
Published in Parasitology (01.12.2019)
Get full text
Journal Article
Protein N-glycosylation is essential for SARS-CoV-2 infection
Casas-Sanchez, Aitor, Romero-Ramirez, Alessandra, Hargreaves, Eleanor, Ellis, Cameron C, Grajeda, Brian I, Estevao, Igor, Patterson, Edward I, Hughes, Grant L, Almeida, Igor C, Zech, Tobias, Acosta-Serrano, Alvaro
Published in bioRxiv (04.06.2021)
Published in bioRxiv (04.06.2021)
Get full text
Paper
Gut-associated bacteria invade the midgut epithelium of Aedes aegypti and stimulate innate immunity and suppress Zika virus infection in cells
Hegde, Shivanand, Voronin, Denis, Casas-Sanchez, Aitor, Saldana, Miguel A, Heinz, Eva, Acosta-Serrano, Alvaro, Popov, Vsevolod L, Chopra, Ashok K, Hughes, Grant L
Published in bioRxiv (16.01.2020)
Published in bioRxiv (16.01.2020)
Get full text
Paper
Trypanosoma brucei colonises the tsetse gut via an immature peritrophic matrix in the proventriculus
Rose, Clair, Dyer, Naomi A, Casas-Sanchez, Aitor, Beckett, Alison J, Solorzano, Carla, Middlehurst, Ben, Marcello, Marco, Lehane, Michael J, Prior, Ian A, Acosta-Serrano, Alvaro
Published in bioRxiv (07.01.2019)
Published in bioRxiv (07.01.2019)
Get full text
Paper
The crystal structure and localization of Trypanosoma brucei invariant surface glycoproteins suggest a more permissive VSG coat in the tsetse-transmitted metacyclic stage
Casas-Sanchez, Aitor, Perally, Samirah, Raghavendran Ramaswamy, Haines, Lee R, Rose, Clair, Yunta, Cristina, Aguilera-Flores, Marcela, Lehane, Michael J, Almeida, Igor C, Boulanger, Martin J, Acosta-Serrano, Alvaro
Published in bioRxiv (26.11.2018)
Published in bioRxiv (26.11.2018)
Get full text
Paper