Structure of a nanobody-stabilized active state of the β2 adrenoceptor
RASMUSSEN, Soren G. F, CHOI, Hee-Jung, SCHNAPP, Andreas, KONETZKI, Ingo, SUNAHARA, Roger K, GELLMAN, Samuel H, PAUTSCH, Alexander, STEYAERT, Jan, WEIS, William I, KOBILKA, Brian K, FUNG, Juan Jose, PARDON, Els, CASAROSA, Paola, PIL SEOK CHAE, DEVREE, Brian T, ROSENBAUM, Daniel M, SUN THIAN, Foon, SUN KOBILKA, Tong
Published in Nature (London) (13.01.2011)
Published in Nature (London) (13.01.2011)
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Journal Article
Preclinical Evaluation of Long-Acting Muscarinic Antagonists: Comparison of Tiotropium and Investigational Drugs
Casarosa, Paola, Bouyssou, Thierry, Germeyer, Sabine, Schnapp, Andreas, Gantner, Florian, Pieper, Michael
Published in The Journal of pharmacology and experimental therapeutics (01.08.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2009)
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Journal Article
Functional and biochemical rationales for the 24-hour-long duration of action of olodaterol
Casarosa, Paola, Kollak, Ines, Kiechle, Tobias, Ostermann, Angela, Schnapp, Andreas, Kiesling, Ralf, Pieper, Michael, Sieger, Peter, Gantner, Florian
Published in The Journal of pharmacology and experimental therapeutics (01.06.2011)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2011)
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Journal Article
Smoke, Choline Acetyltransferase, Muscarinic Receptors, and Fibroblast Proliferation in Chronic Obstructive Pulmonary Disease
Profita, Mirella, Bonanno, Anna, Siena, Liboria, Bruno, Andreina, Ferraro, Maria, Montalbano, Angela Marina, Albano, Giusy Daniela, Riccobono, Loredana, Casarosa, Paola, Pieper, Michael Paul, Gjomarkaj, Mark
Published in The Journal of pharmacology and experimental therapeutics (01.05.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2009)
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Journal Article
Kaposi's Sarcoma-Associated Herpesvirus-Encoded G Protein-Coupled Receptor ORF74 Constitutively Activates p44/p42 MAPK and Akt via Gi and Phospholipase C-Dependent Signaling Pathways
Smit, Martine J., Verzijl, Dennis, Casarosa, Paola, Navis, Marjon, Timmerman, Henk, Leurs, Rob
Published in Journal of Virology (15.02.2002)
Published in Journal of Virology (15.02.2002)
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Journal Article
The Carboxyl Terminus of Human Cytomegalovirus-encoded 7 Transmembrane Receptor US28 Camouflages Agonism by Mediating Constitutive Endocytosis
Waldhoer, Maria, Casarosa, Paola, Rosenkilde, Mette M., Smit, Martine J., Leurs, Rob, Whistler, Jennifer L., Schwartz, Thue W.
Published in The Journal of biological chemistry (23.05.2003)
Published in The Journal of biological chemistry (23.05.2003)
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Journal Article
Constitutive Signaling of the Human Cytomegalovirus-encoded Receptor UL33 Differs from That of Its Rat Cytomegalovirus Homolog R33 by Promiscuous Activation of G Proteins of the Gq, Gi, and Gs Classes
Casarosa, Paola, Gruijthuijsen, Yvonne K., Michel, Detlef, Beisser, Patrick S., Holl, Jens, Fitzsimons, Carlos P., Verzijl, Dennis, Bruggeman, Cathrien A., Mertens, Thomas, Leurs, Rob, Vink, Cornelis, Smit, Martine J.
Published in The Journal of biological chemistry (12.12.2003)
Published in The Journal of biological chemistry (12.12.2003)
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Journal Article
CC and CX3C Chemokines Differentially Interact with the N Terminus of the Human Cytomegalovirus-encoded US28 Receptor
Casarosa, Paola, Waldhoer, Maria, LiWang, Patricia J., Vischer, Henry F., Kledal, Thomas, Timmerman, Henk, Schwartz, Thue W., Smit, Martine J., Leurs, Rob
Published in The Journal of biological chemistry (04.02.2005)
Published in The Journal of biological chemistry (04.02.2005)
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Journal Article
Human Cytomegalovirus Chemokine Receptor US28-induced Smooth Muscle Cell Migration Is Mediated by Focal Adhesion Kinase and Src
Streblow, Daniel N., Vomaske, Jennifer, Smith, Patsy, Melnychuk, Ryan, Hall, Laurel, Pancheva, Dora, Smit, Martine, Casarosa, Paola, Schlaepfer, David D., Nelson, Jay A.
Published in The Journal of biological chemistry (12.12.2003)
Published in The Journal of biological chemistry (12.12.2003)
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Journal Article
Identification of the First Nonpeptidergic Inverse Agonist for a Constitutively Active Viral-encoded G Protein-coupled Receptor
Casarosa, Paola, Menge, Wiro M, Minisini, Rosalba, Otto, Claas, van Heteren, Jane, Jongejan, Aldo, Timmerman, Henk, Moepps, Barbara, Kirchhoff, Frank, Mertens, Thomas, Smit, Martine J, Leurs, Rob
Published in The Journal of biological chemistry (14.02.2003)
Published in The Journal of biological chemistry (14.02.2003)
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Journal Article
The Rat Cytomegalovirus R33-Encoded G Protein-Coupled Receptor Signals in a Constitutive Fashion
Gruijthuijsen, Yvonne K, Casarosa, Paola, Kaptein, Suzanne J F, Broers, Jos L V, Leurs, Rob, Bruggeman, Cathrien A, Smit, Martine J, Vink, Cornelis
Published in Journal of Virology (01.02.2002)
Published in Journal of Virology (01.02.2002)
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Journal Article
Synthesis and Structure−Activity Relationship of the First Nonpeptidergic Inverse Agonists for the Human Cytomegalovirus Encoded Chemokine Receptor US28
Hulshof, Janneke W, Casarosa, Paola, Menge, Wiro M. P. B, Kuusisto, Leena M. S, van der Goot, Henk, Smit, Martine J, de Esch, Iwan J. P, Leurs, Rob
Published in Journal of medicinal chemistry (06.10.2005)
Published in Journal of medicinal chemistry (06.10.2005)
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Journal Article
Identifying Functional Hotspot Residues for Biased Ligand Design in G-Protein-Coupled Receptors
Nivedha, Anita K, Tautermann, Christofer S, Bhattacharya, Supriyo, Lee, Sangbae, Casarosa, Paola, Kollak, Ines, Kiechle, Tobias, Vaidehi, Nagarajan
Published in Molecular pharmacology (01.04.2018)
Published in Molecular pharmacology (01.04.2018)
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Journal Article
Molecular Basis for the Long Duration of Action and Kinetic Selectivity of Tiotropium for the Muscarinic M3 Receptor
Tautermann, Christofer S, Kiechle, Tobias, Seeliger, Daniel, Diehl, Sonja, Wex, Eva, Banholzer, Rolf, Gantner, Florian, Pieper, Michael P, Casarosa, Paola
Published in Journal of medicinal chemistry (14.11.2013)
Published in Journal of medicinal chemistry (14.11.2013)
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Journal Article
Retraction notice to “In vitro anticholinergic drugs affect CD8+ peripheral blood T-cells apoptosis in COPD” [Immunobiology 217/3 (2012) 345–353]
Profita, Mirella, Riccobono, Loredana, Montalbano, Angela Marina, Bonanno, Anna, Ferraro, Maria, Albano, Giusy Daniela, Gerbino, Stefania, Casarosa, Paola, Pieper, Michael Paul, Gjomarkaj, Mark
Published in Immunobiology (1979) (01.05.2024)
Published in Immunobiology (1979) (01.05.2024)
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Journal Article
The constitutive activity of the human muscarinic M3 receptor unmasks differences in the pharmacology of anticholinergics
Casarosa, Paola, Kiechle, Tobias, Sieger, Peter, Pieper, Michael, Gantner, Florian
Published in The Journal of pharmacology and experimental therapeutics (01.04.2010)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2010)
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Journal Article
β2 long-acting and anticholinergic drugs control TGF-β1-mediated neutrophilic inflammation in COPD
Profita, Mirella, Bonanno, Anna, Montalbano, Angela Marina, Albano, Giusy Daniela, Riccobono, Loredana, Siena, Liboria, Ferraro, Maria, Casarosa, Paola, Pieper, Michael Paul, Gjomarkaj, Mark
Published in Biochimica et biophysica acta (01.07.2012)
Published in Biochimica et biophysica acta (01.07.2012)
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Journal Article
Cigarette smoke extract activates human bronchial epithelial cells affecting non-neuronal cholinergic system signalling in vitro
Profita, Mirella, Bonanno, Anna, Montalbano, Angela Marina, Ferraro, Maria, Siena, Liboria, Bruno, Andreina, Girbino, Stefania, Albano, Giusy Daniela, Casarosa, Paola, Pieper, Michael Paul, Gjomarkaj, Mark
Published in Life sciences (1973) (04.07.2011)
Published in Life sciences (1973) (04.07.2011)
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