Single Cell Characterisation of Transcriptional Programmes of Responsive and Resistant Leukaemic Progenitors in IDH2-Mutant Acute Myeloid Leukaemia in the AG221-AML-005 Study
Chatzikyriakou, Prodromos, Silveira, Douglas RA, Casares Aláez, Maria del Pilar, Usukhbayar, Batchimeg, Metzner, Marlen, Vyas, Paresh, Gandhi, Anita K., Risueño, Alberto, Hasan, Maroof, Quek, Lynn
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Impaired Metabolic Plasticity Under Stress Constitutes a Therapeutic Vulnerability in IDH1/2-Mutant Acute Myeloid Leukemia
Sternadt, Dominique, Pereira-Martins, Diego, Silveira, Douglas RA, Chatzikyriakou, Prodromos, Casares Alaez, Maria del Pilar, Weinhaeuser, Isabel, Hogeling, Shanna M, Ammatuna, Emanuele, Huls, Gerwin A., Quek, Lynn, Schuringa, Jan Jacob
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
An Integrated Single Cell Immunogenomic Atlas Reveals Pathways of Clonal Expansion, Inflammation and Dyserythropoiesis in Low and High-Risk Clonal Haematopoiesis
Zheng, Xuesen, Tan, Amandine, Casares Alaez, Maria del Pilar, Mallett, Garry, Kaya, Deniz Ece, Seymen, Nogayhan, Rzepkowska, Marta, Mackie, Sarah, Chatzikyriakou, Prodromos, Bogaanay, Laarni, Lewis, Jen, Hasan, Maroof, Suragani, Rajasekhar N.V.S., Carmichael, James, Mufti, Ghulam, Gandhi, Anita K., Napolitani, Giorgio, Quek, Lynn
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Dysregulation of Stem-Progenitor and Differentiation Programmes through Modulation of Bivalent Chromatin Drives Leukemogenesis in Mutant IDH2 Acute Myeloid Leukaemia
Silveira, Douglas RA RA, Chatzikyriakou, Prodromos, Casares Alaez, Maria del Pilar, Mackie, Sarah, Hulks, Roan, Yavorska, Olena, Siejka-Zielinska, Paulina, Metzner, Marlen, Smith, Alastair, Usukhbayar, Batchimeg, Penard-Lacronique, Virginie, Song, Chunxiao, Gandhi, Anita K., Hasan, Maroof, Vyas, Paresh, Milne, Thomas A., Kriaucionis, Skirmantas, Quek, Lynn
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article