Tobramycin Liquid Crystal Nanoparticles Eradicate Cystic Fibrosis‐Related Pseudomonas aeruginosa Biofilms
Thorn, Chelsea R., Carvalho‐Wodarz, Cristiane de Souza, Horstmann, Justus C., Lehr, Claus‐Michael, Prestidge, Clive A., Thomas, Nicky
Published in Small (Weinheim an der Bergstrasse, Germany) (01.06.2021)
Published in Small (Weinheim an der Bergstrasse, Germany) (01.06.2021)
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Nano‐in‐Microparticles for Aerosol Delivery of Antibiotic‐Loaded, Fucose‐Derivatized, and Macrophage‐Targeted Liposomes to Combat Mycobacterial Infections: In Vitro Deposition, Pulmonary Barrier Interactions, and Targeted Delivery
Huck, Benedikt C., Thiyagarajan, Durairaj, Bali, Aghiad, Boese, Annette, Besecke, Karen F. W., Hozsa, Constantin, Gieseler, Robert K., Furch, Marcus, Carvalho‐Wodarz, Cristiane, Waldow, Franziska, Schwudke, Dominik, Metelkina, Olga, Titz, Alexander, Huwer, Hanno, Schwarzkopf, Konrad, Hoppstädter, Jessica, Kiemer, Alexandra K., Koch, Marcus, Loretz, Brigitta, Lehr, Claus‐Michael
Published in Advanced healthcare materials (01.06.2022)
Published in Advanced healthcare materials (01.06.2022)
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Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration
Thanki, Kaushik, van Eetvelde, Delphine, Geyer, Antonia, Fraire, Juan, Hendrix, Remi, Van Eygen, Hannelore, Putteman, Emma, Sami, Haider, de Souza Carvalho-Wodarz, Cristiane, Franzyk, Henrik, Nielsen, Hanne Mørck, Braeckmans, Kevin, Lehr, Claus-Michael, Ogris, Manfred, Foged, Camilla
Published in Journal of controlled release (28.09.2019)
Published in Journal of controlled release (28.09.2019)
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Journal Article
Triple co-culture of human alveolar epithelium, endothelium and macrophages for studying the interaction of nanocarriers with the air-blood barrier
Costa, Ana, de Souza Carvalho-Wodarz, Cristiane, Seabra, Vítor, Sarmento, Bruno, Lehr, Claus-Michael
Published in Acta biomaterialia (01.06.2019)
Published in Acta biomaterialia (01.06.2019)
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Journal Article
A Custom-Made Device for Reproducibly Depositing Pre-metered Doses of Nebulized Drugs on Pulmonary Cells in vitro
Horstmann, Justus C, Thorn, Chelsea R, Carius, Patrick, Graef, Florian, Murgia, Xabier, de Souza Carvalho-Wodarz, Cristiane, Lehr, Claus-Michael
Published in Frontiers in bioengineering and biotechnology (21.04.2021)
Published in Frontiers in bioengineering and biotechnology (21.04.2021)
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Journal Article
Spray-dried multidrug particles for pulmonary co-delivery of antibiotics with N-acetylcysteine and curcumin-loaded PLGA-nanoparticles
Lababidi, Nashrawan, Montefusco-Pereira, Carlos Victor, de Souza Carvalho-Wodarz, Cristiane, Lehr, Claus-Michael, Schneider, Marc
Published in European journal of pharmaceutics and biopharmaceutics (01.12.2020)
Published in European journal of pharmaceutics and biopharmaceutics (01.12.2020)
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Journal Article
Increased survival and proliferation of the epidemic strain Mycobacterium abscessus subsp. massiliense CRM0019 in alveolar epithelial cells
Ribeiro, Giovanni Monteiro, Matsumoto, Cristianne Kayoko, Real, Fernando, Teixeira, Daniela, Duarte, Rafael Silva, Mortara, Renato Arruda, Leão, Sylvia Cardoso, de Souza Carvalho-Wodarz, Cristiane
Published in BMC microbiology (13.09.2017)
Published in BMC microbiology (13.09.2017)
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Journal Article
Lymphatic endothelial cells are a replicative niche for Mycobacterium tuberculosis
Lerner, Thomas R, de Souza Carvalho-Wodarz, Cristiane, Repnik, Urska, Russell, Matthew R G, Borel, Sophie, Diedrich, Collin R, Rohde, Manfred, Wainwright, Helen, Collinson, Lucy M, Wilkinson, Robert J, Griffiths, Gareth, Gutierrez, Maximiliano G
Published in The Journal of clinical investigation (01.03.2016)
Published in The Journal of clinical investigation (01.03.2016)
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Journal Article
A 3D co-culture of three human cell lines to model the inflamed intestinal mucosa for safety testing of nanomaterials
Susewind, Julia, de Souza Carvalho-Wodarz, Cristiane, Repnik, Urska, Collnot, Eva-Maria, Schneider-Daum, Nicole, Griffiths, Gareth Wyn, Lehr, Claus-Michael
Published in Nanotoxicology (02.01.2016)
Published in Nanotoxicology (02.01.2016)
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Journal Article
PLGA nanocapsules improve the delivery of clarithromycin to kill intracellular Staphylococcus aureus and Mycobacterium abscessus
Anversa Dimer, Frantiescoli, de Souza Carvalho-Wodarz, Cristiane, Goes, Adriely, Cirnski, Katarina, Herrmann, Jennifer, Schmitt, Viktoria, Pätzold, Linda, Abed, Nadia, De Rossi, Chiara, Bischoff, Markus, Couvreur, Patrick, Müller, Rolf, Lehr, Claus-Michael
Published in Nanomedicine (01.02.2020)
Published in Nanomedicine (01.02.2020)
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Journal Article
A pulmonary mucus surrogate for investigating antibiotic permeation and activity against Pseudomonas aeruginosa biofilms
Frisch, Sarah, Boese, Annette, Huck, Benedikt, Horstmann, Justus C, Ho, Duy-Khiet, Schwarzkopf, Konrad, Murgia, Xabier, Loretz, Brigitta, de Souza Carvalho-Wodarz, Cristiane, Lehr, Claus-Michael
Published in Journal of antimicrobial chemotherapy (12.05.2021)
Published in Journal of antimicrobial chemotherapy (12.05.2021)
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Journal Article
Human alveolar epithelial cells expressing tight junctions to model the air-blood barrier
Kuehn, Anna, Kletting, Stephanie, de Souza Carvalho-Wodarz, Cristiane, Repnik, Urska, Griffiths, Gareth, Fischer, Ulrike, Meese, Eckart, Huwer, Hanno, Wirth, Dagmar, May, Tobias, Schneider-Daum, Nicole, Lehr, Claus-Michael
Published in ALTEX, alternatives to animal experimentation (2016)
Published in ALTEX, alternatives to animal experimentation (2016)
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Journal Article
Co-culture of human alveolar epithelial (hAELVi) and macrophage (THP-1) cell lines
Kletting, Stephanie, Barthold, Sarah, Repnik, Urska, Griffiths, Gareth, Loretz, Brigitta, Schneider-Daum, Nicole, de Souza Carvalho-Wodarz, Cristiane, Lehr, Claus-Michael
Published in ALTEX, alternatives to animal experimentation (2018)
Published in ALTEX, alternatives to animal experimentation (2018)
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Journal Article
Polysaccharide Submicrocarrier for Improved Pulmonary Delivery of Poorly Soluble Anti-infective Ciprofloxacin: Preparation, Characterization, and Influence of Size on Cellular Uptake
Ho, Duy-Khiet, Costa, Ana, De Rossi, Chiara, de Souza Carvalho-Wodarz, Cristiane, Loretz, Brigitta, Lehr, Claus-Michael
Published in Molecular pharmaceutics (05.03.2018)
Published in Molecular pharmaceutics (05.03.2018)
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Journal Article
Transferring Microclusters of P. aeruginosa Biofilms to the Air–Liquid Interface of Bronchial Epithelial Cells for Repeated Deposition of Aerosolized Tobramycin
Horstmann, Justus C, Laric, Annabelle, Boese, Annette, Yildiz, Daniela, Röhrig, Teresa, Empting, Martin, Frank, Nicolas, Krug, Daniel, Müller, Rolf, Schneider-Daum, Nicole, de Souza Carvalho-Wodarz, Cristiane, Lehr, Claus-Michael
Published in ACS infectious diseases (14.01.2022)
Published in ACS infectious diseases (14.01.2022)
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Journal Article
Nanoencapsulation of a glucocorticoid improves barrier function and anti-inflammatory effect on monolayers of pulmonary epithelial cell lines
Rigo, Lucas A., Carvalho-Wodarz, Cristiane S., Pohlmann, Adriana R., Guterres, Silvia S., Schneider-Daum, Nicole, Lehr, Claus-Michael, Beck, Ruy C.R.
Published in European journal of pharmaceutics and biopharmaceutics (01.10.2017)
Published in European journal of pharmaceutics and biopharmaceutics (01.10.2017)
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Journal Article
Decoding (patho-)physiology of the lung by advanced in vitro models for developing novel anti-infectives therapies
Montefusco-Pereira, Carlos Victor, Carvalho-Wodarz, Cristiane de Souza, Seeger, Johanna, Kloft, Charlotte, Michelet, Robin, Lehr, Claus-Michael
Published in Drug discovery today (01.01.2021)
Published in Drug discovery today (01.01.2021)
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Journal Article
Modelling the bronchial barrier in pulmonary drug delivery: A human bronchial epithelial cell line supplemented with human tracheal mucus
Murgia, Xabi, Yasar, Hanzey, Carvalho-Wodarz, Cristiane, Loretz, Brigitta, Gordon, Sarah, Schwarzkopf, Konrad, Schaefer, Ulrich, Lehr, Claus-Michael
Published in European journal of pharmaceutics and biopharmaceutics (01.09.2017)
Published in European journal of pharmaceutics and biopharmaceutics (01.09.2017)
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