Optimization of a Series of Bivalent Triazolopyridazine Based Bromodomain and Extraterminal Inhibitors: The Discovery of (3R)‑4-[2-[4-[1-(3-Methoxy-[1,2,4]triazolo[4,3‑b]pyridazin-6-yl)-4-piperidyl]phenoxy]ethyl]-1,3-dimethyl-piperazin-2-one (AZD5153)
Bradbury, Robert H, Callis, Rowena, Carr, Gregory R, Chen, Huawei, Clark, Edwin, Feron, Lyman, Glossop, Steve, Graham, Mark A, Hattersley, Maureen, Jones, Chris, Lamont, Scott G, Ouvry, Gilles, Patel, Anil, Patel, Joe, Rabow, Alfred A, Roberts, Craig A, Stokes, Stephen, Stratton, Natalie, Walker, Graeme E, Ward, Lara, Whalley, David, Whittaker, David, Wrigley, Gail, Waring, Michael J
Published in Journal of medicinal chemistry (08.09.2016)
Published in Journal of medicinal chemistry (08.09.2016)
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Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer
Bradbury, Robert H., Acton, David G., Broadbent, Nicola L., Brooks, A. Nigel, Carr, Gregory R., Hatter, Glenn, Hayter, Barry R., Hill, Kathryn J., Howe, Nicholas J., Jones, Rhys D.O., Jude, David, Lamont, Scott G., Loddick, Sarah A., McFarland, Heather L., Parveen, Zaieda, Rabow, Alfred A., Sharma-Singh, Gorkhn, Stratton, Natalie C., Thomason, Andrew G., Trueman, Dawn, Walker, Graeme E., Wells, Stuart L., Wilson, Joanne, Wood, J. Matthew
Published in Bioorganic & medicinal chemistry letters (01.04.2013)
Published in Bioorganic & medicinal chemistry letters (01.04.2013)
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A novel approach to functionalised 5,7,8,9-tetrahydropyrimido[4,5-b][1,4]diazepin-6-ones using intramolecular palladium-catalysed amidation
Carr, Gregory R., Feron, James L., Johnson, Paul D., Roberts, Craig A., Rudge, David A., Simpson, Iain, Wrigley, Gail L.
Published in Tetrahedron letters (19.09.2012)
Published in Tetrahedron letters (19.09.2012)
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Optimization of a Series of Bivalent Triazolopyridazine Based Bromodomain and Extraterminal Inhibitors: The Discovery of (3R)-4-[2-[4-[1-(3-Methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-4-piperidyl]phenoxylethy]-1,3-dimethyl-piperazin-2-one (AZD5153)
Bradbury, Robert H., Callis, Rowena, Carr, Gregory R., Chen, Huawei, Clark, Edwin, Feron, Lyman, Glossop, Steve, Graham, Mark A., Hattersley, Maureen, Jones, Chris, Lamont, Scott G., Ouvry, Gilles, Patel, Anil, Patel, Joe, Rabow, Alfred A., Roberts, Craig A., Stokes, Stephen, Stratton, Natalie, Walker, Graeme E., Ward, Lara, Whalley, David, Whittaker, David, Wrigley, Gail, Waring, Michael J.
Published in Journal of medicinal chemistry (08.09.2016)
Published in Journal of medicinal chemistry (08.09.2016)
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Journal Article
FROM OUR READERS VALUJET CRASH Regulations concerning old aircraft need to be tightened across the board
CAROL CONEY Snellville, Carr, R Gregory, TROY L. COX Stone Mountain, Edwards, George W, Richardson, Spurgeon, Lee, Mike, TED VARNO Marietta, FRANSEN Atlanta, SCOTT R, STEVE ADKINS Calhoun, LERCH Atlanta, BOBBY R
Published in The Atlanta journal-constitution (2001) (18.05.1996)
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Published in The Atlanta journal-constitution (2001) (18.05.1996)
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