1-(5-TERT-BUTYL-2-ARYL-PYRAZOL-3-YL)-3-[2-FLUORO-4-[(3-OXO-4H-PYRIDO[2,3-B]PYRAZIN-8-YL)OXY]PHENYL]UREA COMPOUNDS AND THEIR THERAPEUTIC USE
SPRINGER, CAROLINE JOY, MARAIS, RICHARD, NICULESCU-DUVAZ, ION, NICULESCU-DUVAZ, DAN, ZAMBON, ALFONSO, GIROTTI, ROMINA
Year of Publication 30.08.2022
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Year of Publication 30.08.2022
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Process for the preparation of 8-(4-aminophenoxy)-4H-pyrido[2,3-b]pyrazin-3-one derivatives
Zambon, Alfonso, Niculescu-Duvaz, Dan, Chubb, Richard, Springer, Caroline Joy
Year of Publication 16.10.2018
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Year of Publication 16.10.2018
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PROCESS FOR THE PREPARATION OF 8-(4-AMINOPHENOXY)-4H-PYRIDO[2,3-B]PYRAZIN-3-ONE DERIVATIVES
ZAMBON, Alfonso, CHUBB, Richard, SPRINGER, Caroline Joy, NICULESCU-DUVAZ, Dan
Year of Publication 22.08.2018
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Year of Publication 22.08.2018
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1-(5-TERT-BUTYL-2-ARYL-PYRAZOL-3-YL)-3-[2-FLUORO-4-[(3-OXO-4H-PYRIDO[2, 3-B]PYRAZIN-8-YL)OXY]PHENYL]UREA DERIVATIVES AS RAF INHIBITORS FOR THE TREATMENT OF CANCER
ZAMBON, Alfonso, MARAIS, Richard, NICULESCU-DUVAZ, Ion, GIROTTI, Romina, SPRINGER, Caroline Joy, NICULESCU-DUVAZ, Dan
Year of Publication 28.01.2020
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Year of Publication 28.01.2020
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1-(5-TERT-BUTYL-2-ARYL-PYRAZOL-3-YL)-3-[2-FLUORO-4-[(3-OXO-4H-PYRIDO[2, 3-B]PYRAZIN-8-YL)OXY]PHENYL]UREA DERIVATIVES AS RAF INHIBITORS FOR THE TREATMENT OF CANCER
SPRINGER, CAROLINE JOY, MARAIS, RICHARD, NICULESCU-DUVAZ, ION, NICULESCU-DUVAZ, DAN, ZAMBON, ALFONSO, GIROTTI, ROMINA
Year of Publication 29.11.2019
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Year of Publication 29.11.2019
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PROCESS FOR THE PREPARATION OF 8-(4-AMINOPHENOXY)-4H-PYRIDO[2,3-B]PYRAZIN-3-ONE DERIVATIVES
Niculescu-Duvaz Dan, Zambon Alfonso, Chubb Richard, Springer Caroline Joy
Year of Publication 19.10.2017
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Year of Publication 19.10.2017
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1-(5-TERT-BUTYL-2-ARYL-PYRAZOL-3-YL)-3-[2-FLUORO-4-[(3-OXO-4H-PYRIDO[2, 3-B]PYRAZIN-8-YL)OXY]PHENYL]UREA DERIVATIVES AS RAF INHIBITORS FOR THE TREATMENT OF CANCER
CAROLINE JOY SPRINGER, RICHARD MARAIS, ROMINA GIROTTI, ALFONSO ZAMBON, DAN NICULESCU-DUVAZ, ION NICULESCU-DUVAZ
Year of Publication 06.08.2019
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Year of Publication 06.08.2019
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1-(5-TERT-BUTYL-2-ARYLPYRAZOL-3-YL)-3-[2-FLUOR-4-[(3-OXO-4H-PYRIDO[2,3-B]PYRAZIN-8-YL)OXY]PHENYL]URINSTOFDERIVATER SOM RAF-INHIBITORER TIL BEHANDLING AF CANCER
ZAMBON, Alfonso, MARAIS, Richard, NICULESCU-DUVAZ, Ion, GIROTTI, Romina, SPRINGER, Caroline Joy, NICULESCU-DUVAZ, Dan
Year of Publication 29.07.2019
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Year of Publication 29.07.2019
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Process for the preparation of 8-(4-aminophenoxy)-4H-pyrido[2,3-B]pyrazin-3-one derivatives
Niculescu-Duvaz Dan, Zambon Alfonso, Chubb Richard, Springer Caroline Joy
Year of Publication 18.07.2017
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Year of Publication 18.07.2017
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1-(5-TERT-BUTYL-2-ARYL-PYRAZOL-3-YL)-3-[2-FLUORO-4-[(3-OXO-4H-PYRIDO[2, 3-B]PYRAZIN-8-YL)OXY]PHENYL]UREA DERIVATIVES AS RAF INHIBITORS FOR THE TREATMENT OF CANCER
ZAMBON, Alfonso, MARAIS, Richard, NICULESCU-DUVAZ, Ion, GIROTTI, Romina, SPRINGER, Caroline Joy, NICULESCU-DUVAZ, Dan
Year of Publication 01.05.2019
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Year of Publication 01.05.2019
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1 -(5-tert-butyl-2-aryl-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido[2, 3-b]pyrazin-8-yl)oxy]phenyl]urea derivatives as RAF inhibitors for the treatment of cancer
Zambon, Alfonso, Girotti, Romina, Niculescu-Duvaz, Ion, Marais, Richard, Niculescu-Duvaz, Dan, Springer, Caroline Joy
Year of Publication 14.02.2019
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Year of Publication 14.02.2019
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1-(5-tert-butyl-2-aryl-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido [2, 3-B]pyrazin- 8-yl)oxy]phenyl]urea derivatives as RAF inhibitors for the treatment of cancer
Zambon, Alfonso, Girotti, Romina, Niculescu-Duvaz, Ion, Marais, Richard, Niculescu-Duvaz, Dan, Springer, Caroline Joy
Year of Publication 01.01.2019
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Year of Publication 01.01.2019
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PROCESS FOR THE PREPARATION OF 8-(4-AMINOPHENOXY)-4H-PYRIDO[2,3-B]PYRAZIN-3-ONE DERIVATIVES
Niculescu-Duvaz Dan, Zambon Alfonso, Chubb Richard, Springer Caroline Joy
Year of Publication 13.10.2016
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Year of Publication 13.10.2016
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PROCESS FOR THE PREPARATION OF 8-(4-AMINOPHENOXY)-4H-PYRIDO[2,3-B]PYRAZIN-3-ONE DERIVATIVES
CHUBB, RICHARD, SPRINGER, CAROLINE JOY, ZAMBON, ALFONSO, NICULESCU-DUVAZ, DAN
Year of Publication 05.10.2016
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Year of Publication 05.10.2016
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DERIVADOS DE 1-(5-TERC-BUTIL-2-ARIL-PIRAZOL-3-IL)-3-[2-FLÚOR-4-[(3- OXO-4H-PIRIDO[2,3-B]PIRAZIN-8-IL)ÓXI]FENIL]UREIA, SEUS USOS, SUA COMPOSIÇÃO FARMACÊUTICA, MÉTODO PARA PREPARAR A MESMA E MÉTODO IN VITRO PARA INIBIR A FUNÇÃO RAF EM UMA CÉLULA
CAROLINE JOY SPRINGER, RICHARD MARAIS, ROMINA GIROTTI, ALFONSO ZAMBON, DAN NICULESCU-DUVAZ, ION NICULESCU-DUVAZ
Year of Publication 06.12.2022
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Year of Publication 06.12.2022
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1-(5-tert-butyl-2-phenyl-2H-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)-phenyl]-urea and related compounds and their use in therapy
Menard Delphine, Niculescu-Duvaz Dan, Marais Richard, Niculescu-Duvaz Ion, Zambon Alfonso, Springer Caroline Joy
Year of Publication 21.11.2017
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Year of Publication 21.11.2017
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1 -(5-TERT-BUTYL-2-ARYL-PYRAZOL-3-YL)-3-[2-FLUORO-4-[(3-OXO-4H-PYRIDO[2, 3-B]PYRAZIN-8-YL)OXY]PHENYL]UREA DERIVATIVES AS RAF INHIBITORS FOR THE TREATMENT OF CANCER
SPRINGER Caroline Joy, GIROTTI Romina, NICULESCU-DUVAZ Dan, MARAIS Richard, NICULESCU-DUVAZ Ion, ZAMBON Alfonso
Year of Publication 19.10.2017
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Year of Publication 19.10.2017
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1-(5-tert-butyl-2-aryl-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea derivatives as RAF inhibitors for the treatment of cancer
Niculescu-Duvaz Dan, Marais Richard, Niculescu-Duvaz Ion, Zambon Alfonso, Girotti Romina, Springer Caroline Joy
Year of Publication 08.08.2017
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Year of Publication 08.08.2017
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PROCESS FOR THE PREPARATION OF 8-(4-AMINOPHENOXY)-4H-PYRIDO[2,3-B]PYRAZIN-3-ONE DERIVATIVES
CHUBB, RICHARD, SPRINGER, CAROLINE JOY, ZAMBON, ALFONSO, NICULESCU-DUVAZ, DAN
Year of Publication 28.05.2015
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Year of Publication 28.05.2015
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1-(5-TERT-BUTYL-2-PHENYL-2H-PYRAZOL-3-YL)-3-[2-FLUORO-4-(1-METHYL-2-OXO-2,3-DIHYDRO-1H-IMIDAZO[4,5-B]PYRIDIN-7-YLOXY)-PHENYL]-UREA AND RELATED COMPOUNDS AND THEIR USE IN THERAPY
MENARD Delphine, SPRINGER Caroline Joy, NICULESCU-DUVAZ Dan, MARAIS Richard, NICULESCU-DUVAZ Ion, ZAMBON Alfonso
Year of Publication 23.03.2017
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Year of Publication 23.03.2017
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