Extreme population differences in the human zinc transporter ZIP4 (SLC39A4) are explained by positive selection in Sub-Saharan Africa
Engelken, Johannes, Carnero-Montoro, Elena, Pybus, Marc, Andrews, Glen K, Lalueza-Fox, Carles, Comas, David, Sekler, Israel, de la Rasilla, Marco, Rosas, Antonio, Stoneking, Mark, Valverde, Miguel A, Vicente, Rubén, Bosch, Elena
Published in PLoS genetics (01.02.2014)
Published in PLoS genetics (01.02.2014)
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Genome-wide integrated DNA methylome and transcriptome analysis reveals a strong dysregulated myeloid component in the epigenetic landscape of Systemic Sclerosis
Martínez-López, Javier, Ortiz-Fernandez, Lourdes, Estupiñán-Moreno, Elkyn, Kerick, Martin, Andrés-León, Eduardo, Terron-Camero, Laura C, Carnero-Montoro, Elena, Barturen, Guillermo, Beretta, Lorenzo, Almeida, Isabel, Alarcón-Riquelme, Marta E, Ballestar, Esteban, Acosta-Herrera, Marialbert, Martín, Javier
Published in Arthritis & rheumatology (Hoboken, N.J.) (28.10.2024)
Published in Arthritis & rheumatology (Hoboken, N.J.) (28.10.2024)
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Whole blood DNA methylation analysis reveals respiratory environmental traits involved in COVID-19 severity following SARS-CoV-2 infection
Barturen, Guillermo, Carnero-Montoro, Elena, Martínez-Bueno, Manuel, Rojo-Rello, Silvia, Sobrino, Beatriz, Porras-Perales, Óscar, Alcántara-Domínguez, Clara, Bernardo, David, Alarcón-Riquelme, Marta E.
Published in Nature communications (06.08.2022)
Published in Nature communications (06.08.2022)
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Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health
Tsai, Pei-Chien, Glastonbury, Craig A, Eliot, Melissa N, Bollepalli, Sailalitha, Yet, Idil, Castillo-Fernandez, Juan E, Carnero-Montoro, Elena, Hardiman, Thomas, Martin, Tiphaine C, Vickers, Alice, Mangino, Massimo, Ward, Kirsten, Pietiläinen, Kirsi H, Deloukas, Panos, Spector, Tim D, Viñuela, Ana, Loucks, Eric B, Ollikainen, Miina, Kelsey, Karl T, Small, Kerrin S, Bell, Jordana T
Published in Clinical epigenetics (20.10.2018)
Published in Clinical epigenetics (20.10.2018)
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Expression Quantitative Trait Locus Analysis in Systemic Sclerosis Identifies New Candidate Genes Associated With Multiple Aspects of Disease Pathology
Kerick, Martin, González‐Serna, David, Carnero‐Montoro, Elena, Teruel, Maria, Acosta‐Herrera, Marialbert, Makowska, Zuzanna, Buttgereit, Anne, Babaei, Sepideh, Barturen, Guillermo, López‐Isac, Elena, Lesche, Ralf, Beretta, Lorenzo, Alarcon‐Riquelme, Marta E., Martin, Javier, Vigone, Barbara, Pers, Jacques‐Olivier, Saraux, Alain, Devauchelle‐Pensec, Valérie, Cornec, Divi, Jousse‐Joulin, Sandrine, Lauwerys, Bernard, Ducreux, Julie, Maudoux, Anne‐Lise, Vasconcelos, Carlos, Tavares, Ana, Neves, Esmeralda, Faria, Raquel, Brandão, Mariana, Campar, Ana, Marinho, António, Farinha, Fátima, Almeida, Isabel, Mantecón, Miguel Angel Gonzalez‐Gay, Alonso, Ricardo Blanco, Martínez, Alfonso Corrales, Cervera, Ricard, Rodríguez‐Pintó, Ignasi, Espinosa, Gerard, Lories, Rik, De Langhe, Ellen, Hunzelmann, Nicolas, Belz, Doreen, Witte, Torsten, Baerlecken, Niklas, Stummvoll, Georg, Zauner, Michael, Lehner, Michaela, Collantes, Eduardo, Ortega‐Castro, Rafaela, Aguirre‐Zamorano, Mª Angeles, Escudero‐Contreras, Alejandro, Castro‐Villegas, Mª Carmen, Ortego, Norberto, Roldán, María Concepción Fernández, Raya, Enrique, Moleón, Inmaculada Jiménez, de Ramon, Enrique, Quintero, Isabel Díaz, Meroni, Pier Luigi, Gerosa, Maria, Schioppo, Tommaso, Artusi, Carolina, Chizzolini, Carlo, Zuber, Aleksandra, Wynar, Donatienne, Kovács, Laszló, Balog, Attila, Deák, Magdolna, Bocskai, Márta, Dulic, Sonja, Kádár, Gabriella, Hiepe, Falk, Gerl, Velia, Thiel, Silvia, Maresca, Manuel Rodriguez, López‐Berrio, Antonio, Aguilar‐Quesada, Rocío, Navarro‐Linares, Héctor
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2021)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2021)
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Impact of the functional CD5 polymorphism A471V on the response of chronic lymphocytic leukaemia to conventional chemotherapy regimens
Delgado, Julio, Bielig, Torsten, Bonet, Lizette, Carnero‐Montoro, Elena, Puente, Xose S., Colomer, Dolors, Bosch, Elena, Campo, Elias, Lozano, Francisco
Published in British journal of haematology (01.04.2017)
Published in British journal of haematology (01.04.2017)
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O5 Exploring the impact of genome-wide DNA methylation alterations on chromosome X inactivation and female lupus
Castellini-Pérez, Olivia, Povedano-Espejo, Elena, Barturen, Guillermo, Azri, Abir, Dominguez, Ruth, Alarcón-Riquelme, Marta E, Carnero-Montoro, Elena
Published in Lupus science & medicine (14.03.2024)
Published in Lupus science & medicine (14.03.2024)
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Epigenome-Wide Comparative Study Reveals Key Differences Between Mixed Connective Tissue Disease and Related Systemic Autoimmune Diseases
Carnero-Montoro, Elena, Barturen, Guillermo, Povedano, Elena, Kerick, Martin, Martinez-Bueno, Manuel, Ballestar, Esteban, Martin, Javier, Teruel, María, Alarcón-Riquelme, Marta E
Published in Frontiers in immunology (2019)
Published in Frontiers in immunology (2019)
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O15 B cell, T cell, cytotoxic/NK cell, and mitochondrial gene dysregulation patterns separate neuropsychiatric systemic lupus erythematosus patients into two distinct subgroups with differential anticipated response to targeted therapies
Lindblom, Julius, Nikolopoulos, Dionysis, Toro-Domínguez, Daniel, Carnero-Montoro, Elena, Borghi, Maria Orietta, Castillo, Jessica, Iacobaeus, Ellen, Enman, Yvonne, Mohan, Chandra, Beretta, Lorenzo, Alarcón-Riquelme, Marta E, Barturen, Guillermo, Parodis, Ioannis
Published in Lupus science & medicine (14.03.2024)
Published in Lupus science & medicine (14.03.2024)
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O23 Interferon upregulation and B and plasma cell gene dysregulation patterns reveal three distinct lupus nephritis subgroups with differential anticipated response to targeted therapies
Parodis, Ioannis, Lindblom, Julius, Toro-Domínguez, Daniel, Beretta, Lorenzo, Borghi, Maria Orietta, Castillo, Jessica, Carnero-Montoro, Elena, Enman, Yvonne, Mohan, Chandra, Alarcón-Riquelme, Marta E, Barturen, Guillermo, Nikolopoulos, Dionysis
Published in Lupus science & medicine (14.03.2024)
Published in Lupus science & medicine (14.03.2024)
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Journal Article
Analysis of ancestral and functionally relevant CD5 variants in systemic lupus erythematosus patients
Cenit, Maria Carmen, Martínez-Florensa, Mario, Consuegra, Marta, Bonet, Lizette, Carnero-Montoro, Elena, Armiger, Noelia, Caballero-Baños, Miguel, Arias, Maria Teresa, Benitez, Daniel, Ortego-Centeno, Norberto, de Ramón, Enrique, Sabio, José Mario, García-Hernández, Francisco J, Tolosa, Carles, Suárez, Ana, González-Gay, Miguel A, Bosch, Elena, Martín, Javier, Lozano, Francisco
Published in PloS one (17.11.2014)
Published in PloS one (17.11.2014)
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Analysis of Five Gene Sets in Chimpanzees Suggests Decoupling between the Action of Selection on Protein-Coding and on Noncoding Elements
Santpere, Gabriel, Carnero-Montoro, Elena, Petit, Natalia, Serra, François, Hvilsom, Christina, Rambla, Jordi, Heredia-Genestar, Jose Maria, Halligan, Daniel L, Dopazo, Hernan, Navarro, Arcadi, Bosch, Elena
Published in Genome biology and evolution (01.06.2015)
Published in Genome biology and evolution (01.06.2015)
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A basket genetic trial of the vasculitides
Carnero-Montoro, Elena, Alarcón-Riquelme, Marta E.
Published in Nature reviews. Rheumatology (01.09.2023)
Published in Nature reviews. Rheumatology (01.09.2023)
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Journal Article
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
Hemani, Gibran, Dekkers, Koen F., Castillo-Fernandez, Juan, Luijk, René, Carnero-Montoro, Elena, Lawson, Daniel J., Burrows, Kimberley, Suderman, Matthew, Bretherick, Andrew D., Richardson, Tom G., Klughammer, Johanna, Sharp, Gemma, Al Khleifat, Ahmad, Shatunov, Aleksey, Iacoangeli, Alfredo, Ho, Karen M., Söderhäll, Cilla, Soriano-Tárraga, Carolina, Giralt-Steinhauer, Eva, Corcoran, David L., Sugden, Karen, Kasela, Silva, Cardona, Alexia, Day, Felix R., Viberti, Clara, Lerro, Michael, Mandaviya, Pooja, Zeng, Yanni, Clarke, Toni-Kim, Walker, Rosie M., Czamara, Darina, Marioni, Riccardo E., Lin, Tian, Awaloff, Yvonne, Germain, Marine, Aïssi, Dylan, Zwamborn, Ramona, van Eijk, Kristel, Dekker, Annelot, Hottenga, Jouke-Jan, Willemsen, Gonneke, Xu, Cheng-Jian, Barturen, Guillermo, Kerick, Martin, Wang, Carol, Melton, Phillip, Elliott, Hannah R., Shin, Jean, Bernard, Manon, Yet, Idil, Smart, Melissa, Shaw, Chris, Al Chalabi, Ammar, Pershagen, Göran, Melén, Erik, Jiménez-Conde, Jordi, Roquer, Jaume, Montgomery, Grant W., Moffitt, Terrie E., Milani, Lili, Sacerdote, Carlotta, Panico, Salvatore, Caspi, Avshalom, Gagnon, France, Ollikainen, Miina, Kaprio, Jaakko, Felix, Janine F., Rivadeneira, Fernando, Tiemeier, Henning, van IJzendoorn, Marinus H., Uitterlinden, André G., Jaddoe, Vincent W. V., Haley, Chris, Evans, Kathryn L., Murray, Alison, Lahti, Jari, Nohr, Ellen A., Hansen, Torben, Morgen, Camilla S., Bustamante, Mariona, Sunyer, Jordi, Holloway, John W., Zhang, Hongmei, Deary, Ian J., Starr, John M., Beekman, Marian, Morange, Pierre-Emmanuel, Trégouët, David-Alexandre, de Geus, Eco J. C., Brunekreef, Bert, Koppelman, Gerard H., Alarcón-Riquelme, Marta E., Ikram, M. Arfan, Hughes, Alun D., Kumari, Meena, Visscher, Peter M., Davey Smith, George, Bock, Christoph, Bell, Jordana T., Relton, Caroline L.
Published in Nature genetics (01.09.2021)
Published in Nature genetics (01.09.2021)
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Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases
Barturen, Guillermo, Babaei, Sepideh, Català‐Moll, Francesc, Martínez‐Bueno, Manuel, Makowska, Zuzanna, Carmona‐Sáez, Pedro, Toro‐Domínguez, Daniel, Carnero‐Montoro, Elena, Teruel, María, Kerick, Martin, Acosta‐Herrera, Marialbert, Le Lann, Lucas, Jamin, Christophe, Rodríguez‐Ubreva, Javier, García‐Gómez, Antonio, Buttgereit, Anne, Hayat, Sikander, Mueller, Joerg, Lesche, Ralf, Hernandez‐Fuentes, Maria, Juarez, Maria, Rowley, Tania, Marañón, Concepción, Gomes Anjos, Tania, Aguilar‐Quesada, Rocío, López‐Berrio, Antonio, Rodriguez Maresca, Manuel, Navarro‐Linares, Héctor, Azevedo, Nancy, Brandão, Mariana, Campar, Ana, Farinha, Fátima, Marinho, António, Neves, Esmeralda, Vasconcelos, Carlos, Trombetta, Elena, Montanelli, Gaia, Vigone, Barbara, Alvarez‐Errico, Damiana, Li, Tianlu, Thiagaran, Divya, Blanco Alonso, Ricardo, Genre, Fernanda, Gonzalez‐Gay, Miguel A., Remuzgo, Sara, Ubilla Garcia, Begoña, Cervera, Ricard, Espinosa, Gerard, Rodríguez‐Pintó, Ignasi, Belz, Doreen, Hunzelmann, Nicolas, Baerlecken, Niklas, Kniesch, Katja, Lehner, Michaela, Stummvoll, Georg, Zauner, Michael, Aguirre‐Zamorano, Maria Angeles, Barbarroja, Nuria, Castro‐Villegas, Maria Carmen, Ramon, Enrique, Díaz Quintero, Isabel, Fernández Roldán, María Concepción, Jiménez Gómez, Yolanda, Jiménez Moleón, Inmaculada, Lopez‐Pedrera, Rosario, Ortega‐Castro, Rafaela, Ortego, Norberto, Raya, Enrique, Gerosa, Maria, Meroni, Pier Luigi, Schioppo, Tommaso, De Groof, Aurélie, Ducreux, Julie, Lauwerys, Bernard, Maudoux, Anne‐Lise, Cornec, Divi, Devauchelle‐Pensec, Valérie, Jousse‐Joulin, Sandrine, Jouve, Pierre‐Emmanuel, Rouvière, Bénédicte, Saraux, Alain, Simon, Quentin, Dufour, Aleksandra, Wynar, Donatienne, Bocskai, Márta, Dulic, Sonja, Kádár, Gabriella, Kovács, László, Cheng, Qingyu, Hiepe, Falk, Thiel, Silvia, Rinaldis, Emanuele, Benschop, Robert J., Dow, Ernst R., Wojcik, Jerome, Renaudineau, Yves, Beretta, Lorenzo, McDonald, Fiona, Pers, Jacques‐Olivier, Alarcón‐Riquelme, Marta E.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.06.2021)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.06.2021)
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Corrigendum to 'Distinct gene dysregulation patterns herald precision medicine potentiality in systemic lupus erythematosus' J. Autoimmun. 136 (April 2023) 103025
Lindblom, Julius, Toro-Domínguez, Daniel, Carnero-Montoro, Elena, Beretta, Lorenzo, Borghi, Maria Orietta, Castillo, Jessica, Enman, Yvonne, Mohan, Chandra, Alarcón-Riquelme, Marta E, Barturen, Guillermo, Parodis, Ioannis
Published in Journal of autoimmunity (01.11.2023)
Published in Journal of autoimmunity (01.11.2023)
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An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis
Liu, Jun, Carnero-Montoro, Elena, van Dongen, Jenny, Lent, Samantha, Nedeljkovic, Ivana, Ligthart, Symen, Tsai, Pei-Chien, Martin, Tiphaine C., Mandaviya, Pooja R., Jansen, Rick, Peters, Marjolein J., Duijts, Liesbeth, Jaddoe, Vincent W. V., Tiemeier, Henning, Felix, Janine F., Willemsen, Gonneke, de Geus, Eco J. C., Chu, Audrey Y., Levy, Daniel, Hwang, Shih-Jen, Bressler, Jan, Gondalia, Rahul, Salfati, Elias L., Herder, Christian, Hidalgo, Bertha A., Tanaka, Toshiko, Moore, Ann Zenobia, Lemaitre, Rozenn N., Jhun, Min A, Smith, Jennifer A., Sotoodehnia, Nona, Bandinelli, Stefania, Ferrucci, Luigi, Arnett, Donna K., Grallert, Harald, Assimes, Themistocles L., Hou, Lifang, Baccarelli, Andrea, Whitsel, Eric A., van Dijk, Ko Willems, Amin, Najaf, Uitterlinden, André G., Sijbrands, Eric J. G., Franco, Oscar H., Dehghan, Abbas, Spector, Tim D., Dupuis, Josée, Hivert, Marie-France, Rotter, Jerome I., Meigs, James B., Pankow, James S., van Meurs, Joyce B. J., Isaacs, Aaron, Boomsma, Dorret I., Bell, Jordana T., Demirkan, Ayşe, van Duijn, Cornelia M.
Published in Nature communications (13.06.2019)
Published in Nature communications (13.06.2019)
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Scoring personalized molecular portraits identify Systemic Lupus Erythematosus subtypes and predict individualized drug responses, symptomatology and disease progression
Toro-Domínguez, Daniel, Martorell-Marugán, Jordi, Martinez-Bueno, Manuel, López-Domínguez, Raúl, Carnero-Montoro, Elena, Barturen, Guillermo, Goldman, Daniel, Petri, Michelle, Carmona-Sáez, Pedro, Alarcón-Riquelme, Marta E
Published in Briefings in bioinformatics (20.09.2022)
Published in Briefings in bioinformatics (20.09.2022)
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