Doxorubicin-induced mitophagy and mitochondrial damage is associated with dysregulation of the PINK1/parkin pathway
Yin, Jian, Guo, Jiabin, Zhang, Qiang, Cui, Lan, Zhang, Li, Zhang, Tingfen, Zhao, Jun, Li, Jin, Middleton, Alistair, Carmichael, Paul L., Peng, Shuangqing
Published in Toxicology in vitro (01.09.2018)
Published in Toxicology in vitro (01.09.2018)
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Journal Article
A Next-Generation Risk Assessment Case Study for Coumarin in Cosmetic Products
Baltazar, Maria T, Cable, Sophie, Carmichael, Paul L, Cubberley, Richard, Cull, Tom, Delagrange, Mona, Dent, Matthew P, Hatherell, Sarah, Houghton, Jade, Kukic, Predrag, Li, Hequn, Lee, Mi-Young, Malcomber, Sophie, Middleton, Alistair M, Moxon, Thomas E, Nathanail, Alexis V, Nicol, Beate, Pendlington, Ruth, Reynolds, Georgia, Reynolds, Joe, White, Andrew, Westmoreland, Carl
Published in Toxicological sciences (01.07.2020)
Published in Toxicological sciences (01.07.2020)
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Journal Article
Extracting biological information with computational analysis of Fourier-transform infrared (FTIR) biospectroscopy datasets: current practices to future perspectives
Trevisan, Júlio, Angelov, Plamen P, Carmichael, Paul L, Scott, Andrew D, Martin, Francis L
Published in Analyst (London) (21.07.2012)
Published in Analyst (London) (21.07.2012)
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Journal Article
Implementing organ-on-chip in a next-generation risk assessment of chemicals: a review
Nitsche, Katharina S., Müller, Iris, Malcomber, Sophie, Carmichael, Paul L., Bouwmeester, Hans
Published in Archives of toxicology (01.03.2022)
Published in Archives of toxicology (01.03.2022)
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Journal Article
IRootLab: a free and open-source MATLAB toolbox for vibrational biospectroscopy data analysis
Trevisan, Júlio, Angelov, Plamen P, Scott, Andrew D, Carmichael, Paul L, Martin, Francis L
Published in Bioinformatics (15.04.2013)
Published in Bioinformatics (15.04.2013)
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Journal Article
Erythropoietin activates SIRT1 to protect human cardiomyocytes against doxorubicin-induced mitochondrial dysfunction and toxicity
Cui, Lan, Guo, Jiabin, Zhang, Qiang, Yin, Jian, Li, Jin, Zhou, Wei, Zhang, Tingfen, Yuan, Haitao, Zhao, Jun, Zhang, Li, Carmichael, Paul L., Peng, Shuangqing
Published in Toxicology letters (05.06.2017)
Published in Toxicology letters (05.06.2017)
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Journal Article
Identifying and Characterizing Stress Pathways of Concern for Consumer Safety in Next-Generation Risk Assessment
Hatherell, Sarah, Baltazar, Maria T, Reynolds, Joe, Carmichael, Paul L, Dent, Matthew, Li, Hequn, Ryder, Stephanie, White, Andrew, Walker, Paul, Middleton, Alistair M
Published in Toxicological sciences (01.07.2020)
Published in Toxicological sciences (01.07.2020)
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Journal Article
Ready for regulatory use: NAMs and NGRA for chemical safety assurance
Carmichael, Paul L, Baltazar, Maria T, Cable, Sophie, Cochrane, Stella, Dent, Matthew, Li, Hequn, Middleton, Alistair, Muller, Iris, Reynolds, Georgia, Westmoreland, Carl, White, Andrew
Published in ALTEX, alternatives to animal experimentation (01.01.2022)
Published in ALTEX, alternatives to animal experimentation (01.01.2022)
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Journal Article
Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment
Adeleye, Yeyejide, Andersen, Melvin, Clewell, Rebecca, Davies, Michael, Dent, Matthew, Edwards, Sue, Fowler, Paul, Malcomber, Sophie, Nicol, Beate, Scott, Andrew, Scott, Sharon, Sun, Bin, Westmoreland, Carl, White, Andrew, Zhang, Qiang, Carmichael, Paul L
Published in Toxicology (Amsterdam) (05.06.2015)
Published in Toxicology (Amsterdam) (05.06.2015)
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Journal Article
Adaptive Posttranslational Control in Cellular Stress Response Pathways and Its Relationship to Toxicity Testing and Safety Assessment
Zhang, Qiang, Bhattacharya, Sudin, Pi, Jingbo, Clewell, Rebecca A, Carmichael, Paul L, Andersen, Melvin E
Published in Toxicological sciences (01.10.2015)
Published in Toxicological sciences (01.10.2015)
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Journal Article
Are Non-animal Systemic Safety Assessments Protective? A Toolbox and Workflow
Middleton, Alistair M, Reynolds, Joe, Cable, Sophie, Baltazar, Maria Teresa, Li, Hequn, Bevan, Samantha, Carmichael, Paul L, Dent, Matthew Philip, Hatherell, Sarah, Houghton, Jade, Kukic, Predrag, Liddell, Mark, Malcomber, Sophie, Nicol, Beate, Park, Benjamin, Patel, Hiral, Scott, Sharon, Sparham, Chris, Walker, Paul, White, Andrew
Published in Toxicological sciences (25.08.2022)
Published in Toxicological sciences (25.08.2022)
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Journal Article
Next generation risk assessment of human exposure to estrogens using safe comparator compound values based on in vitro bioactivity assays
van Tongeren, Tessa C. A., Wang, Si, Carmichael, Paul L., Rietjens, Ivonne M. C. M., Li, Hequn
Published in Archives of toxicology (01.06.2023)
Published in Archives of toxicology (01.06.2023)
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Journal Article
Employing Dietary Comparators to Perform Risk Assessments for Anti-Androgens Without Using Animal Data
Dent, Matthew P, Li, Hequn, Carmichael, Paul L, Martin, Francis L
Published in Toxicological sciences (01.02.2019)
Published in Toxicological sciences (01.02.2019)
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Journal Article
Quantitative phosphoproteomics reveal cellular responses from caffeine, coumarin and quercetin in treated HepG2 cells
Zhang, Zhenpeng, Zhang, Yao, Li, Yuan, Jiang, Songhao, Xu, Feng, Li, Kaixuan, Chang, Lei, Gao, Huiying, Kukic, Predrag, Carmichael, Paul Lawford, Liddell, Mark, Li, Jin, Zhang, Qiang, Lyu, Zhitang, Peng, Shuangqing, Zuo, Tao, Tulum, Liz, Xu, Ping
Published in Toxicology and applied pharmacology (15.08.2022)
Published in Toxicology and applied pharmacology (15.08.2022)
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Journal Article
Microphysiological Systems Evaluation: Experience of TEX-VAL Tissue Chip Testing Consortium
Rusyn, Ivan, Sakolish, Courtney, Kato, Yuki, Stephan, Clifford, Vergara, Leoncio, Hewitt, Philip, Bhaskaran, Vasanthi, Davis, Myrtle, Hardwick, Rhiannon N, Ferguson, Stephen S, Stanko, Jason P, Bajaj, Piyush, Adkins, Karissa, Sipes, Nisha S, Hunter, E Sidney, Baltazar, Maria T, Carmichael, Paul L, Sadh, Kritika, Becker, Richard A
Published in Toxicological sciences (28.07.2022)
Published in Toxicological sciences (28.07.2022)
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Journal Article
An in vitro-in silico workflow for predicting renal clearance of PFAS
Lin, Hsing-Chieh, Sakolish, Courtney, Moyer, Haley L., Carmichael, Paul L., Baltazar, Maria T., Ferguson, Stephen S., Stanko, Jason P., Hewitt, Philip, Rusyn, Ivan, Chiu, Weihsueh A.
Published in Toxicology and applied pharmacology (01.08.2024)
Published in Toxicology and applied pharmacology (01.08.2024)
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Journal Article
Vision of a near future: Bridging the human health–environment divide. Toward an integrated strategy to understand mechanisms across species for chemical safety assessment
Rivetti, Claudia, Allen, Timothy E.H., Brown, James B., Butler, Emma, Carmichael, Paul L., Colbourne, John K., Dent, Matthew, Falciani, Francesco, Gunnarsson, Lina, Gutsell, Steve, Harrill, Joshua A., Hodges, Geoff, Jennings, Paul, Judson, Richard, Kienzler, Aude, Margiotta-Casaluci, Luigi, Muller, Iris, Owen, Stewart F., Rendal, Cecilie, Russell, Paul J., Scott, Sharon, Sewell, Fiona, Shah, Imran, Sorrel, Ian, Viant, Mark R., Westmoreland, Carl, White, Andrew, Campos, Bruno
Published in Toxicology in vitro (01.02.2020)
Published in Toxicology in vitro (01.02.2020)
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Journal Article
A PGC-1α-Mediated Transcriptional Network Maintains Mitochondrial Redox and Bioenergetic Homeostasis against Doxorubicin-Induced Toxicity in Human Cardiomyocytes: Implementation of TT21C
Yuan, Haitao, Zhang, Qiang, Guo, Jiabin, Zhang, Tingfen, Zhao, Jun, Li, Jin, White, Andrew, Carmichael, Paul L, Westmoreland, Carl, Peng, Shuangqing
Published in Toxicological sciences (01.04.2016)
Published in Toxicological sciences (01.04.2016)
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