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Burke, James R, Cheng, Lihong, Gillooly, Kathleen M, Strnad, Joann, Zupa-Fernandez, Adriana, Catlett, Ian M, Zhang, Yifan, Heimrich, Elizabeth M, McIntyre, Kim W, Cunningham, Mark D, Carman, Julie A, Zhou, Xiadi, Banas, Dana, Chaudhry, Charu, Li, Sha, D'Arienzo, Celia, Chimalakonda, Anjaneya, Yang, XiaoXia, Xie, Jenny H, Pang, Jian, Zhao, Qihong, Rose, Shawn M, Huang, Jinwen, Moslin, Ryan M, Wrobleski, Stephen T, Weinstein, David S, Salter-Cid, Luisa M
Published in Science translational medicine (24.07.2019)
Published in Science translational medicine (24.07.2019)
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HuR is required for IL-17-induced Act1-mediated CXCL1 and CXCL5 mRNA stabilization
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IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression
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Published in Nature communications (31.05.2017)
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Cytotoxic CD8 + T cells target citrullinated antigens in rheumatoid arthritis
Moon, Jae-Seung, Younis, Shady, Ramadoss, Nitya S, Iyer, Radhika, Sheth, Khushboo, Sharpe, Orr, Rao, Navin L, Becart, Stephane, Carman, Julie A, James, Eddie A, Buckner, Jane H, Deane, Kevin D, Holers, V Michael, Goodman, Susan M, Donlin, Laura T, Davis, Mark M, Robinson, William H
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Published in Nature communications (19.01.2023)
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Circulating T Cell Subpopulations Correlate With Immune Responses at the Tumor Site and Clinical Response to PD1 Inhibition in Non-Small Cell Lung Cancer
Manjarrez-Orduño, Nataly, Menard, Laurence C, Kansal, Selena, Fischer, Paul, Kakrecha, Bijal, Jiang, Can, Cunningham, Mark, Greenawalt, Danielle, Patel, Vishal, Yang, Minghui, Golhar, Ryan, Carman, Julie A, Lezhnin, Sergey, Dai, Hongyue, Kayne, Paul S, Suchard, Suzanne J, Bernstein, Steven H, Nadler, Steven G
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Published in Frontiers in immunology (03.08.2018)
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TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation
Zhang, Cun-Jin, Jiang, Meiling, Zhou, Hao, Liu, Weiwei, Wang, Chenhui, Kang, Zizhen, Han, Bing, Zhang, Quanri, Chen, Xing, Xiao, Jianxin, Fisher, Amanda, Kaiser, William J, Murayama, Masanori A, Iwakura, Yoichiro, Gao, Ji, Carman, Julie, Dongre, Ashok, Dubyak, George, Abbott, Derek W, Shi, Fu-Dong, Ransohoff, Richard M, Li, Xiaoxia
Published in The Journal of clinical investigation (01.12.2018)
Published in The Journal of clinical investigation (01.12.2018)
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IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes
Zhou, Hao, Wang, Han, Yu, Minjia, Schugar, Rebecca C, Qian, Wen, Tang, Fangqiang, Liu, Weiwei, Yang, Hui, McDowell, Ruth E, Zhao, Junjie, Gao, Ji, Dongre, Ashok, Carman, Julie A, Yin, Mei, Drazba, Judith A, Dent, Robert, Hine, Christopher, Chen, Yeong-Renn, Smith, Jonathan D, Fox, Paul L, Brown, J Mark, Li, Xiaoxia
Published in Nature immunology (01.10.2020)
Published in Nature immunology (01.10.2020)
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IL-17A-Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis
Zepp, Jarod A, Zhao, Junjie, Liu, Caini, Bulek, Katazyna, Wu, Ling, Chen, Xing, Hao, Yujun, Wang, Zhenghe, Wang, Xinxin, Ouyang, Wenjun, Kalady, Matthew F, Carman, Julie, Yang, Wen-Pin, Zhu, Jun, Blackburn, Clare, Huang, Yina H, Hamilton, Thomas A, Su, Bing, Li, Xiaoxia
Published in The Journal of immunology (1950) (01.12.2017)
Published in The Journal of immunology (1950) (01.12.2017)
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Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity
Dudhgaonkar, Shailesh, Ranade, Sourabh, Nagar, Jignesh, Subramani, Siva, Prasad, Durga Shiv, Karunanithi, Preethi, Srivastava, Ratika, Venkatesh, Kamala, Selvam, Sabariya, Krishnamurthy, Prasad, Mariappan, T Thanga, Saxena, Ajay, Fan, Li, Stetsko, Dawn K, Holloway, Deborah A, Li, Xin, Zhu, Jun, Yang, Wen-Pin, Ruepp, Stefan, Nair, Satheesh, Santella, Joseph, Duncia, John, Hynes, John, McIntyre, Kim W, Carman, Julie A
Published in The Journal of immunology (1950) (01.02.2017)
Published in The Journal of immunology (1950) (01.02.2017)
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The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90
Wang, Chenhui, Wu, Ling, Bulek, Katarzyna, Martin, Bradley N, Zepp, Jarod A, Kang, Zizhen, Liu, Caini, Herjan, Tomasz, Misra, Saurav, Carman, Julie A, Gao, Ji, Dongre, Ashok, Han, Shujie, Bunting, Kevin D, Ko, Jennifer S, Xiao, Hui, Kuchroo, Vijay K, Ouyang, Wenjun, Li, Xiaoxia
Published in Nature immunology (01.01.2013)
Published in Nature immunology (01.01.2013)
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The Transcriptome of Paired Major and Minor Salivary Gland Tissue in Patients With Primary Sjögren’s Syndrome
Verstappen, Gwenny M., Gao, Lu, Pringle, Sarah, Haacke, Erlin A., van der Vegt, Bert, Liefers, Silvia C., Patel, Vishal, Hu, Yanhua, Mukherjee, Sumanta, Carman, Julie, Menard, Laurence C., Spijkervet, Frederik K. L., Vissink, Arjan, Bootsma, Hendrika, Kroese, Frans G. M.
Published in Frontiers in immunology (06.07.2021)
Published in Frontiers in immunology (06.07.2021)
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Development of a Molecular Signature to Monitor Pharmacodynamic Responses Mediated by In Vivo Administration of Glucocorticoids
Hu, Yanhua, Carman, Julie A., Holloway, Deborah, Kansal, Selena, Fan, Li, Goldstine, Christine, Lee, Deborah, Somerville, John E., Latek, Robert, Townsend, Robert, Johnsen, Alyssa, Connolly, Sean, Bandyopadhyay, Somnath, Shadick, Nancy, Weinblatt, Michael E., Furie, Richard, Nadler, Steven G.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.08.2018)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.08.2018)
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Act1 is a negative regulator in T and B cells via direct inhibition of STAT3
Zhang, Cun-Jin, Wang, Chenhui, Jiang, Meiling, Gu, Chunfang, Xiao, Jianxin, Chen, Xing, Martin, Bradley N, Tang, Fangqiang, Yamamoto, Erin, Xian, Yibo, Wang, Han, Li, Fengling, Sartor, R Balfour, Smith, Howard, Husni, M Elaine, Shi, Fu-Dong, Gao, Ji, Carman, Julie, Dongre, Ashok, McKarns, Susan C, Coppieters, Ken, Jørgensen, Trine N, Leonard, Warren J, Li, Xiaoxia
Published in Nature communications (16.07.2018)
Published in Nature communications (16.07.2018)
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IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs
Zhou, Hao, Bulek, Katarzyna, Li, Xiao, Herjan, Tomasz, Yu, Minjia, Qian, Wen, Wang, Han, Zhou, Gao, Chen, Xing, Yang, Hui, Hong, Lingzi, Zhao, Junjie, Qin, Luke, Fukuda, Koichi, Flotho, Annette, Gao, Ji, Dongre, Ashok, Carman, Julie A, Kang, Zizhen, Su, Bing, Kern, Timothy S, Smith, Jonathan D, Hamilton, Thomas A, Melchior, Frauke, Fox, Paul L, Li, Xiaoxia
Published in eLife (09.10.2017)
Published in eLife (09.10.2017)
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PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO): protocol for a multicentre, open-label, randomised controlled trial
Euden, Joanne, Thomas-Jones, Emma, Aston, Stephen, Brookes-Howell, Lucy, Carman, Julie, Carrol, Enitan, Gilbert, Stephanie, Howard, Philip, Hood, Kerenza, Inada-Kim, Matthew, Llewelyn, Martin, McGill, Fiona, Milosevic, Sarah, Niessen, Louis Wihelmus, Nsutebu, Emmanuel, Pallmann, Philip, Schmidt, Paul, Taylor-Robinson, David, Welters, Ingeborg, Todd, Stacy, French, Neil, Clarkstone, Sam, Hughes, Jacqui, Meister, Lena, Tabner, Andrew, Barlow, Gavin, Body, Richard, Bradburn, Mike, Daniels, Jane, Richards, Emma, Brain, Angela, Walker, Sarah, Goodacre, Steve, Scarborough, Matthew, O'Shea, Sian, James, Claire
Published in BMJ open (13.06.2022)
Published in BMJ open (13.06.2022)
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Azaxanthene Based Selective Glucocorticoid Receptor Modulators: Design, Synthesis, and Pharmacological Evaluation of (S)-4-(5-(1-((1,3,4-Thiadiazol-2-yl)amino)-2-methyl-1-oxopropan-2-yl)-5H-chromeno[2,3-b]pyridin-2-yl)-2-fluoro-N,N-dimethylbenzamide (BMS-776532) and Its Methylene Homologue (BMS-791826)
Weinstein, David S, Gong, Hua, Doweyko, Arthur M, Cunningham, Mark, Habte, Sium, Wang, Jin Hong, Holloway, Deborah A, Burke, Christine, Gao, Ling, Guarino, Victor, Carman, Julie, Somerville, John E, Shuster, David, Salter-Cid, Luisa, Dodd, John H, Nadler, Steven G, Barrish, Joel C
Published in Journal of medicinal chemistry (27.10.2011)
Published in Journal of medicinal chemistry (27.10.2011)
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Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis
Nair, Satheesh, Kumar, Sreekantha Ratna, Paidi, Venkatram Reddy, Sistla, Ramesh, Kantheti, Durgarao, Polimera, Subba Rao, Thangavel, Soodamani, Mukherjee, Amrita Jha, Das, Mitalee, Bhide, Rajeev S, Pitts, William J, Murugesan, Natesan, Dudhgoankar, Shailesh, Nagar, Jignesh, Subramani, Siva, Mazumder, Debarati, Carman, Julie A, Holloway, Deborah A, Li, Xin, Fereshteh, Mark P, Ruepp, Stefan, Palanisamy, Kamalavenkatesh, Mariappan, T. Thanga, Maddi, Srinivas, Saxena, Ajay, Elzinga, Paul, Chimalakonda, Anjaneya, Ruan, Qian, Ghosh, Kaushik, Bose, Sucharita, Sack, John, Yan, Chunhong, Kiefer, Susan E, Xie, Dianlin, Newitt, John A, Saravanakumar, S. Pon, Rampulla, Richard A, Barrish, Joel C, Carter, Percy H, Hynes, John
Published in ACS medicinal chemistry letters (09.07.2020)
Published in ACS medicinal chemistry letters (09.07.2020)
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Comment on: Polonsky et al. Structured self-monitoring of blood glucose significantly reduces A1C levels in poorly controlled, noninsulin-treated type 2 diabetes: results from the structured testing program study. Diabetes Care 2011;34:262-267
Stephens, Jeffrey W, Carman, Julie E, Brooks, Caroline J, Lyons, Ronan A, Ford, David V, Price, David E, Bain, Stephen C
Published in Diabetes care (01.05.2011)
Published in Diabetes care (01.05.2011)
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Abatacept Does Not Induce Direct Gene Expression Changes in Antigen-Presenting Cells
Carman, Julie A, Davis, Patricia M, Yang, Wen-Pin, Zhu, Jun, Chang, Han, He, Aiqing, Truong, Amy, Suchard, Suzanne J, Nadler, Steven G
Published in Journal of clinical immunology (01.07.2009)
Published in Journal of clinical immunology (01.07.2009)
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Direct association of tristetraprolin with the nucleoporin CAN/Nup214
Carman, Julie A, Nadler, Steven G
Published in Biochemical and biophysical research communications (05.03.2004)
Published in Biochemical and biophysical research communications (05.03.2004)
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