Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology
François-Moutal, Liberty, Scott, David Donald, Ambrose, Andrew J, Zerio, Christopher J, Rodriguez-Sanchez, Marina, Dissanayake, Kumara, May, Danielle G, Carlson, Jacob M, Barbieri, Edward, Moutal, Aubin, Roux, Kyle J, Shorter, James, Khanna, Rajesh, Barmada, Sami J, McGurk, Leeanne, Khanna, May
Published in Scientific reports (17.05.2022)
Published in Scientific reports (17.05.2022)
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Journal Article
Discovery and Characterization of 2,5-Substituted Benzoic Acid Dual Inhibitors of the Anti-apoptotic Mcl‑1 and Bfl‑1 Proteins
Kump, Karson J, Miao, Lei, Mady, Ahmed S. A, Ansari, Nurul H, Shrestha, Uttar K, Yang, Yuting, Pal, Mohan, Liao, Chenzhong, Perdih, Andrej, Abulwerdi, Fardokht A, Chinnaswamy, Krishnapriya, Meagher, Jennifer L, Carlson, Jacob M, Khanna, May, Stuckey, Jeanne A, Nikolovska-Coleska, Zaneta
Published in Journal of medicinal chemistry (12.03.2020)
Published in Journal of medicinal chemistry (12.03.2020)
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An Allosteric Modulator of RNA Binding Targeting the N‑Terminal Domain of TDP-43 Yields Neuroprotective Properties
Mollasalehi, Niloufar, Francois-Moutal, Liberty, Scott, David D, Tello, Judith A, Williams, Haley, Mahoney, Brendan, Carlson, Jacob M, Dong, Yue, Li, Xingli, Miranda, Victor G, Gokhale, Vijay, Wang, Wei, Barmada, Sami J, Khanna, May
Published in ACS chemical biology (20.11.2020)
Published in ACS chemical biology (20.11.2020)
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Abstract LB-226: Discovery of small molecule Mcl-1 and Bfl-1 inhibitors
Kump, Karson J., Miao, Lei, Mady, Ahmed A., Ansari, Nurul H., Shrestha, Uttar K., Yang, Yuting, Pal, Mohan, Liao, Chenzhong, Perdih, Andrej, Abulwerdi, Fardokht A., Chinnaswamy, Krishnapriya, Meagher, Jennifer L., Carlson, Jacob M., Khanna, May, Stuckey, Jeanne A., Nikolovska-Coleska, Zaneta
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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