Synthesis of the Hypoxia-Inducible Factor-2α (HIF-2α) Inhibitor, 3-[(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile (PT2977, Belzutifan); Efficient Replication of Established Approaches
Hamal, Khagendra B., Pavlich, Cyprian I., Carlson, Graham J., Ching Wong, Yu, Zhao, Fangzhou, Zhang, Qing, Klausmeyer, Kevin K., Pinney, Kevin G.
Published in Tetrahedron letters (19.09.2023)
Published in Tetrahedron letters (19.09.2023)
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Bioreductively activatable prodrug conjugates of phenstatin designed to target tumor hypoxia
Winn, Blake A., Shi, Zhe, Carlson, Graham J., Wang, Yifan, Nguyen, Benson L., Kelly, Evan M., Ross, R. David, Hamel, Ernest, Chaplin, David J., Trawick, Mary L., Pinney, Kevin G.
Published in Bioorganic & medicinal chemistry letters (01.02.2017)
Published in Bioorganic & medicinal chemistry letters (01.02.2017)
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Synthesis and biological evaluation of structurally diverse α-conformationally restricted chalcones and related analogues
Maguire, Casey J, Carlson, Graham J, Ford, Jacob W, Strecker, Tracy E, Hamel, Ernest, Trawick, Mary Lynn, Pinney, Kevin G
Published in MedChemComm (14.08.2019)
Published in MedChemComm (14.08.2019)
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Oxygen‐Sensing Chemiluminescent Iridium(III) 1,2‐Dioxetanes: Unusual Coordination and Activity
Kagalwala, Husain N., Bueno, Lorena, Wanniarachchi, Hashini, Unruh, Daniel K., Hamal, Khagendra B., Pavlich, Cyprian I., Carlson, Graham J., Pinney, Kevin G., Mason, Ralph P., Lippert, Alexander R.
Published in Analysis & sensing (01.01.2023)
Published in Analysis & sensing (01.01.2023)
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Journal Article
Synthesis of the Hypoxia-Inducible Factor-2α (HIF-2α) Inhibitor, 3-(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yloxy-5-fluorobenzonitrile (PT2977, Belzutifan); Efficient Replication of Established Approaches
Hamal, Khagendra B, Pavlich, Cyprian I, Carlson, Graham J, Wong, Yu Ching, Zhao, Fangzhou, Zhang, Qing, Klausmeyer, Kevin K, Pinney, Kevin G
Published in Tetrahedron letters (19.09.2023)
Published in Tetrahedron letters (19.09.2023)
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Journal Article
Synthesis and biological evaluation of structurally diverse α-conformationally restricted chalcones and related analogues† †Electronic supplementary information (ESI) available: Supplementary data including (1H NMR, 13C NMR, HRMS, HPLC) for target compounds and intermediates (1H NMR, 13C NMR, only), X-ray crystallography (CCDC 1899786–1899788) for compounds 2a, 5a, and 5b, and a table of biological data including standard deviations associated with this article can be found in the online supplem
Maguire, Casey J., Carlson, Graham J., Ford, Jacob W., Strecker, Tracy E., Hamel, Ernest, Trawick, Mary Lynn, Pinney, Kevin G.
Published in MedChemComm (04.06.2019)
Published in MedChemComm (04.06.2019)
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Abstract 6206: Discerning vasculature destruction caused by novel vascular disrupting agents examined by optical and multispectral optoacoustic imaging
Wanniarachchi, Hashini I., Schuetze, Regan, Arango, Lorena, Hamal, Khagendra, Carlson, Graham J., Pavlich, Cyprian, Deng, Yuling, Trawick, Mary L., Pinney, Kevin G., Liu, Li, Mason, Ralph P.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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