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Yue, Eddy W, Higley, C. Anne, DiMeo, Susan V, Carini, David J, Nugiel, David A, Benware, Carrie, Benfield, Pamela A, Burton, Catherine R, Cox, Sarah, Grafstrom, Robert H, Sharp, Diane M, Sisk, Lisa M, Boylan, John F, Muckelbauer, Jodi K, Smallwood, Angela M, Chen, Haiying, Chang, Chong-Hwan, Seitz, Steven P, Trainor, George L
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Published in Journal of medicinal chemistry (21.11.2002)
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Published in Bioorganic & medicinal chemistry letters (01.01.2016)
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Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives
Carini, David J, Duncia, John V, Aldrich, Paul E, Chiu, Andrew T, Johnson, Alexander L, Pierce, Michael E, Price, William A, Santella, Joseph B, Wells, Gregory J
Published in Journal of medicinal chemistry (01.08.1991)
Published in Journal of medicinal chemistry (01.08.1991)
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Identification of selective inhibitors of cyclin dependent kinase 4
Carini, David J, Kaltenbach, Robert F, Liu, Jie, Benfield, Pamela A, Boylan, John, Boisclair, Michael, Brizuela, Leonardo, Burton, Catherine R, Cox, Sarah, Grafstrom, Robert, Harrison, Barbara A, Harrison, Kimberly, Akamike, Emeka, Markwalder, Jay A, Nakano, Yuki, Seitz, Steven P, Sharp, Diane M, Trainor, George L, Sielecki, Thais M
Published in Bioorganic & medicinal chemistry letters (20.08.2001)
Published in Bioorganic & medicinal chemistry letters (20.08.2001)
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Design and Synthesis of Isoxazoline Derivatives as Factor Xa Inhibitors. 1
Quan, Mimi L, Liauw, Ann Y, Ellis, Christopher D, Pruitt, James R, Carini, David J, Bostrom, Lori L, Huang, Peggy P, Harrison, Kimberly, Knabb, Robert M, Thoolen, Martin J, Wong, Pancras C, Wexler, Ruth R
Published in Journal of medicinal chemistry (29.07.1999)
Published in Journal of medicinal chemistry (29.07.1999)
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The discovery of potent nonpeptide angiotensin II receptor antagonists: a new class of potent antihypertensives
Duncia, John V, Chiu, Andrew T, Carini, David J, Gregory, George B, Johnson, Alexander L, Price, William A, Wells, Gregory J, Wong, Pancras C, Calabrese, Joseph C, Timmermans, Pieter B. M. W. M
Published in Journal of medicinal chemistry (01.05.1990)
Published in Journal of medicinal chemistry (01.05.1990)
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Practical synthesis and regioselective alkylation of methyl 4(5)-(pentafluoroethyl)-2-propylimidazole-5(4)-carboxylate to give DuP 532, a potent angiotensin II antagonist
Pierce, Michael E, Carini, David J, Huhn, George F, Wells, Gregory J, Arnett, John F
Published in Journal of organic chemistry (01.08.1993)
Published in Journal of organic chemistry (01.08.1993)
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Identification of angiotensin II receptor subtypes
Chiu, Andrew T., Herblin, William F., McCall, Dale E., Ardecky, Robert J., Carini, David J., Duncia, John V., Pease, Lori J., Wong, Pancras C., Wexler, Ruth R., Johnson, Alexander L., Timmermans, Pieter B.M.W.M.
Published in Biochemical and biophysical research communications (30.11.1989)
Published in Biochemical and biophysical research communications (30.11.1989)
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The discovery of DuP 753, a potent, orally active nonpeptide angiotensin II receptor antagonist
Duncia, J V, Carini, D J, Chiu, A T, Johnson, A L, Price, W A, Wong, P C, Wexler, R R, Timmermans, P B
Published in Medicinal research reviews (01.03.1992)
Published in Medicinal research reviews (01.03.1992)
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Hypotensive Action of DuP 753, an Angiotensin II Antagonist, in Spontaneously Hypertensive Rats Nonpeptide Angiotensin II Receptor Antagonists: X
Wong, Pancras C, Price, William A, Chiu, Andrew T, Duncia, John V, Carini, David J, Wexler, Ruth R, Johnson, Alexander L, Timmermans, Pieter B.M.W.M
Published in Hypertension (Dallas, Tex. 1979) (01.05.1990)
Published in Hypertension (Dallas, Tex. 1979) (01.05.1990)
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Angiotensin II Receptor Antagonists From Discovery to Antihypertensive Drugs
Timmermans, Pieter B.M.W.M, Carini, David J, Chiu, Andrew T, Duncia, John V, Price, William A, Wells, Gregory J, Wong, Pancras C, Wexler, Ruth R, Johnson, Alexander L
Published in Hypertension (Dallas, Tex. 1979) (01.11.1991)
Published in Hypertension (Dallas, Tex. 1979) (01.11.1991)
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DuP 532: A second generation of nonpeptide angiotensin II receptor antagonists
Chiu, Andrew T., Carini, David J., Duncia, John V., Leung, Kam H., McCall, Dale E., Price, William A., Wong, Pancras C., Smith, Ronald D., Wexler, Ruth R., Timmermans, Pieter B.M.W.M., Chang, Raymond S.L., Lotti, Victor J.
Published in Biochemical and biophysical research communications (31.05.1991)
Published in Biochemical and biophysical research communications (31.05.1991)
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Balanced angiotensin II receptor antagonists. III. The effects of substitution at the imidazole 5-position
Santella, Joseph B., Duncia, John V., Ensinger, Carol L., VanAtten, Mary K., Carini, David J., Wexler, Ruth R., Chiu, Andrew T., Wong, Pancras C., Timmermans, Pieter B.M.W.M.
Published in Bioorganic & medicinal chemistry letters (01.09.1994)
Published in Bioorganic & medicinal chemistry letters (01.09.1994)
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The preparation of (perfluoroalkyl)imidazoles as nonpeptide angiotensin II receptor antagonists
Carini, David J., Chiu, Andrew T., Wong, Pancras C., Johnson, Alexander L., Wexler, Ruth R., Timmermans, Pieter B.M.W.M.
Published in Bioorganic & medicinal chemistry letters (01.05.1993)
Published in Bioorganic & medicinal chemistry letters (01.05.1993)
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