A Deep Learning Approach to Antibiotic Discovery
Stokes, Jonathan M., Yang, Kevin, Swanson, Kyle, Jin, Wengong, Cubillos-Ruiz, Andres, Donghia, Nina M., MacNair, Craig R., French, Shawn, Carfrae, Lindsey A., Bloom-Ackermann, Zohar, Tran, Victoria M., Chiappino-Pepe, Anush, Badran, Ahmed H., Andrews, Ian W., Chory, Emma J., Church, George M., Brown, Eric D., Jaakkola, Tommi S., Barzilay, Regina, Collins, James J.
Published in Cell (20.02.2020)
Published in Cell (20.02.2020)
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Journal Article
Overcoming mcr-1 mediated colistin resistance with colistin in combination with other antibiotics
MacNair, Craig R., Stokes, Jonathan M., Carfrae, Lindsey A., Fiebig-Comyn, Aline A., Coombes, Brian K., Mulvey, Michael R., Brown, Eric D.
Published in Nature communications (31.01.2018)
Published in Nature communications (31.01.2018)
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Journal Article
A Deep Learning Approach to Antibiotic Discovery
Stokes, Jonathan M., Yang, Kevin, Swanson, Kyle, Jin, Wengong, Cubillos-Ruiz, Andres, Donghia, Nina M., MacNair, Craig R., French, Shawn, Carfrae, Lindsey A., Bloom-Ackermann, Zohar, Tran, Victoria M., Chiappino-Pepe, Anush, Badran, Ahmed H., Andrews, Ian W., Chory, Emma J., Church, George M., Brown, Eric D., Jaakkola, Tommi S., Barzilay, Regina, Collins, James J.
Published in Cell (16.04.2020)
Published in Cell (16.04.2020)
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Journal Article
Uncovering the Hidden Antibiotic Potential of Cannabis
Farha, Maya A, El-Halfawy, Omar M, Gale, Robert T, MacNair, Craig R, Carfrae, Lindsey A, Zhang, Xiong, Jentsch, Nicholas G, Magolan, Jakob, Brown, Eric D
Published in ACS infectious diseases (13.03.2020)
Published in ACS infectious diseases (13.03.2020)
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Journal Article
The aryl hydrocarbon receptor and FOS mediate cytotoxicity induced by Acinetobacter baumannii
Kew, Chun, Prieto-Garcia, Cristian, Bhattacharya, Anshu, Tietgen, Manuela, MacNair, Craig R., Carfrae, Lindsey A., Mello-Vieira, João, Klatt, Stephan, Cheng, Yi-Lin, Rathore, Rajeshwari, Gradhand, Elise, Fleming, Ingrid, Tan, Man-Wah, Göttig, Stephan, Kempf, Volkhard A. J., Dikic, Ivan
Published in Nature communications (11.09.2024)
Published in Nature communications (11.09.2024)
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Journal Article
Inhibiting fatty acid synthesis overcomes colistin resistance
Carfrae, Lindsey A., Rachwalski, Kenneth, French, Shawn, Gordzevich, Rodion, Seidel, Laura, Tsai, Caressa N., Tu, Megan M., MacNair, Craig R., Ovchinnikova, Olga G., Clarke, Bradley R., Whitfield, Chris, Brown, Eric D.
Published in Nature microbiology (01.06.2023)
Published in Nature microbiology (01.06.2023)
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Journal Article
Preclinical Development of Pentamidine Analogs Identifies a Potent and Nontoxic Antibiotic Adjuvant
MacNair, Craig R, Farha, Maya A, Serrano-Wu, Michael H, Lee, Katie K, Hubbard, Brian, Côté, Jean-Philippe, Carfrae, Lindsey A, Tu, Megan M, Gaulin, Jeffrey L, Hunt, Diana K, Hung, Deborah T, Brown, Eric D
Published in ACS infectious diseases (08.04.2022)
Published in ACS infectious diseases (08.04.2022)
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Journal Article
Overcoming Acquired and Native Macrolide Resistance with Bicarbonate
Farha, Maya A, MacNair, Craig R, Carfrae, Lindsey A, El Zahed, Sara S, Ellis, Michael J, Tran, Hiu-Ki R, McArthur, Andrew G, Brown, Eric D
Published in ACS infectious diseases (09.10.2020)
Published in ACS infectious diseases (09.10.2020)
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Journal Article
Mimicking the human environment in mice reveals that inhibiting biotin biosynthesis is effective against antibiotic-resistant pathogens
Carfrae, Lindsey A., MacNair, Craig R., Brown, Christopher M., Tsai, Caressa N., Weber, Brent S., Zlitni, Soumaya, Rao, Vishwas N., Chun, Joshua, Junop, Murray S., Coombes, Brian K., Brown, Eric D.
Published in Nature microbiology (01.01.2020)
Published in Nature microbiology (01.01.2020)
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Journal Article
Silent but deadly: IS200 promotes pathogenicity in Salmonella Typhimurium
Ellis, Michael J., Carfrae, Lindsey A., Macnair, Craig R., Trussler, Ryan S., Brown, Eric D., Haniford, David B.
Published in RNA biology (01.02.2018)
Published in RNA biology (01.02.2018)
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Journal Article
CARD 2023: expanded curation, support for machine learning, and resistome prediction at the Comprehensive Antibiotic Resistance Database
Alcock, Brian P, Huynh, William, Chalil, Romeo, Smith, Keaton W, Raphenya, Amogelang R, Wlodarski, Mateusz A, Edalatmand, Arman, Petkau, Aaron, Syed, Sohaib A, Tsang, Kara K, Baker, Sheridan J C, Dave, Mugdha, McCarthy, Madeline C, Mukiri, Karyn M, Nasir, Jalees A, Golbon, Bahar, Imtiaz, Hamna, Jiang, Xingjian, Kaur, Komal, Kwong, Megan, Liang, Zi Cheng, Niu, Keyu C, Shan, Prabakar, Yang, Jasmine Y J, Gray, Kristen L, Hoad, Gemma R, Jia, Baofeng, Bhando, Timsy, Carfrae, Lindsey A, Farha, Maya A, French, Shawn, Gordzevich, Rodion, Rachwalski, Kenneth, Tu, Megan M, Bordeleau, Emily, Dooley, Damion, Griffiths, Emma, Zubyk, Haley L, Brown, Eric D, Maguire, Finlay, Beiko, Robert G, Hsiao, William W L, Brinkman, Fiona S L, Van Domselaar, Gary, McArthur, Andrew G
Published in Nucleic acids research (06.01.2023)
Published in Nucleic acids research (06.01.2023)
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