Biallelic mutations in IRF8 impair human NK cell maturation and function
Mace, Emily M, Bigley, Venetia, Gunesch, Justin T, Chinn, Ivan K, Angelo, Laura S, Care, Matthew A, Maisuria, Sheetal, Keller, Michael D, Togi, Sumihito, Watkin, Levi B, LaRosa, David F, Jhangiani, Shalini N, Muzny, Donna M, Stray-Pedersen, Asbjørg, Coban Akdemir, Zeynep, Smith, Jansen B, Hernández-Sanabria, Mayra, Le, Duy T, Hogg, Graham D, Cao, Tram N, Freud, Aharon G, Szymanski, Eva P, Savic, Sinisa, Collin, Matthew, Cant, Andrew J, Gibbs, Richard A, Holland, Steven M, Caligiuri, Michael A, Ozato, Keiko, Paust, Silke, Doody, Gina M, Lupski, James R, Orange, Jordan S
Published in The Journal of clinical investigation (01.01.2017)
Published in The Journal of clinical investigation (01.01.2017)
Get full text
Journal Article
IDHwt glioblastomas can be stratified by their transcriptional response to standard treatment, with implications for targeted therapy
Tanner, Georgette, Barrow, Rhiannon, Ajaib, Shoaib, Al-Jabri, Muna, Ahmed, Nazia, Pollock, Steven, Finetti, Martina, Rippaus, Nora, Bruns, Alexander F, Syed, Khaja, Poulter, James A, Matthews, Laura, Hughes, Thomas, Wilson, Erica, Johnson, Colin, Varn, Frederick S, Brüning-Richardson, Anke, Hogg, Catherine, Droop, Alastair, Gusnanto, Arief, Care, Matthew A, Cutillo, Luisa, Westhead, David R, Short, Susan C, Jenkinson, Michael D, Brodbelt, Andrew, Chakrabarty, Aruna, Ismail, Azzam, Verhaak, Roel G W, Stead, Lucy F
Published in Genome Biology (07.02.2024)
Published in Genome Biology (07.02.2024)
Get full text
Journal Article
In vitro generation of long-lived human plasma cells
Cocco, Mario, Stephenson, Sophie, Care, Matthew A, Newton, Darren, Barnes, Nicholas A, Davison, Adam, Rawstron, Andy, Westhead, David R, Doody, Gina M, Tooze, Reuben M
Published in The Journal of immunology (1950) (15.12.2012)
Published in The Journal of immunology (1950) (15.12.2012)
Get full text
Journal Article
Network Analysis Identifies Proinflammatory Plasma Cell Polarization for Secretion of ISG15 in Human Autoimmunity
Care, Matthew A, Stephenson, Sophie J, Barnes, Nicholas A, Fan, Im, Zougman, Alexandre, El-Sherbiny, Yasser M, Vital, Edward M, Westhead, David R, Tooze, Reuben M, Doody, Gina M
Published in The Journal of immunology (1950) (15.08.2016)
Published in The Journal of immunology (1950) (15.08.2016)
Get full text
Journal Article
TLR Adaptor Protein MYD88 Mediates Sensitivity to HDAC Inhibitors via a Cytokine-Dependent Mechanism
New, Maria, Sheikh, Semira, Bekheet, Mina, Olzscha, Heidi, Thezenas, Marie-Laetitia, Care, Matthew A, Fotheringham, Susan, Tooze, Reuben M, Kessler, Benedikt, La Thangue, Nicholas B
Published in Cancer research (Chicago, Ill.) (01.12.2016)
Published in Cancer research (Chicago, Ill.) (01.12.2016)
Get full text
Journal Article
A microarray platform-independent classification tool for cell of origin class allows comparative analysis of gene expression in diffuse large B-cell lymphoma
Care, Matthew A, Barrans, Sharon, Worrillow, Lisa, Jack, Andrew, Westhead, David R, Tooze, Reuben M
Published in PloS one (12.02.2013)
Published in PloS one (12.02.2013)
Get full text
Journal Article
SPIB and BATF provide alternate determinants of IRF4 occupancy in diffuse large B-cell lymphoma linked to disease heterogeneity
Care, Matthew A, Cocco, Mario, Laye, Jon P, Barnes, Nicholas, Huang, Yuanxue, Wang, Ming, Barrans, Sharon, Du, Ming, Jack, Andrew, Westhead, David R, Doody, Gina M, Tooze, Reuben M
Published in Nucleic acids research (08.07.2014)
Published in Nucleic acids research (08.07.2014)
Get full text
Journal Article
Gene-expression profiling of bortezomib added to standard chemoimmunotherapy for diffuse large B-cell lymphoma (REMoDL-B): an open-label, randomised, phase 3 trial
Davies, Andrew, Cummin, Thomas E, Barrans, Sharon, Maishman, Tom, Mamot, Christoph, Novak, Urban, Caddy, Josh, Stanton, Louise, Kazmi-Stokes, Shamim, McMillan, Andrew, Fields, Paul, Pocock, Christopher, Collins, Graham P, Stephens, Richard, Cucco, Francesco, Clipson, Alexandra, Sha, Chulin, Tooze, Reuben, Care, Matthew A, Griffiths, Gareth, Du, Ming-Qing, Westhead, David R, Burton, Catherine, Johnson, Peter W M
Published in The lancet oncology (01.05.2019)
Published in The lancet oncology (01.05.2019)
Get full text
Journal Article
Molecular High-Grade B-Cell Lymphoma: Defining a Poor-Risk Group That Requires Different Approaches to Therapy
Sha, Chulin, Barrans, Sharon, Cucco, Francesco, Bentley, Michael A, Care, Matthew A, Cummin, Thomas, Kennedy, Hannah, Thompson, Joe S, Uddin, Rahman, Worrillow, Lisa, Chalkley, Rebecca, van Hoppe, Moniek, Ahmed, Sophia, Maishman, Tom, Caddy, Josh, Schuh, Anna, Mamot, Christoph, Burton, Catherine, Tooze, Reuben, Davies, Andrew, Du, Ming-Qing, Johnson, Peter W M, Westhead, David R
Published in Journal of clinical oncology (20.01.2019)
Published in Journal of clinical oncology (20.01.2019)
Get full text
Journal Article
APRIL Drives a Coordinated but Diverse Response as a Foundation for Plasma Cell Longevity
Stephenson, Sophie, Care, Matthew A, Doody, Gina M, Tooze, Reuben M
Published in The Journal of immunology (1950) (01.09.2022)
Published in The Journal of immunology (1950) (01.09.2022)
Get full text
Journal Article
Distinct genetic changes reveal evolutionary history and heterogeneous molecular grade of DLBCL with MYC/BCL2 double-hit
Cucco, Francesco, Barrans, Sharon, Sha, Chulin, Clipson, Alexandra, Crouch, Simon, Dobson, Rachel, Chen, Zi, Thompson, Joe Sneath, Care, Matthew A., Cummin, Thomas, Caddy, Josh, Liu, Hongxiang, Robinson, Anne, Schuh, Anna, Fitzgibbon, Jude, Painter, Daniel, Smith, Alexandra, Roman, Eve, Tooze, Reuben, Burton, Catherine, Davies, Andrew J., Westhead, David R., Johnson, Peter W. M., Du, Ming-Qing
Published in Leukemia (01.05.2020)
Published in Leukemia (01.05.2020)
Get full text
Journal Article
Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation
Bigley, Venetia, Maisuria, Sheetal, Cytlak, Urszula, Jardine, Laura, Care, Matthew A., Green, Kile, Gunawan, Merry, Milne, Paul, Dickinson, Rachel, Wiscombe, Sarah, Parry, David, Doffinger, Rainer, Laurence, Arian, Fonseca, Claudia, Stoevesandt, Oda, Gennery, Andrew, Cant, Andrew, Tooze, Reuben, Simpson, A. John, Hambleton, Sophie, Savic, Sinisa, Doody, Gina, Collin, Matthew
Published in Journal of allergy and clinical immunology (01.06.2018)
Published in Journal of allergy and clinical immunology (01.06.2018)
Get full text
Journal Article
A System for In Vitro Generation of Mature Murine Plasma Cells Uncovers Differential Blimp-1 / Prdm1 Promoter Usage
Robinson, Emily, Care, Matthew A, Walker, Kieran, Campbell, Michelle, Tooze, Reuben M, Doody, Gina M
Published in The Journal of immunology (1950) (15.01.2022)
Published in The Journal of immunology (1950) (15.01.2022)
Get full text
Journal Article
Site-1 protease function is essential for the generation of antibody secreting cells and reprogramming for secretory activity
Al-Maskari, Muna, Care, Matthew A., Robinson, Emily, Cocco, Mario, Tooze, Reuben M., Doody, Gina M.
Published in Scientific reports (25.09.2018)
Published in Scientific reports (25.09.2018)
Get full text
Journal Article
Growth Factor-like Gene Regulation Is Separable from Survival and Maturation in Antibody-Secreting Cells
Stephenson, Sophie, Care, Matthew A, Fan, Im, Zougman, Alexandre, Westhead, David R, Doody, Gina M, Tooze, Reuben M
Published in The Journal of immunology (1950) (15.02.2019)
Published in The Journal of immunology (1950) (15.02.2019)
Get full text
Journal Article
Whole genome expression profiling based on paraffin embedded tissue can be used to classify diffuse large B-cell lymphoma and predict clinical outcome
Barrans, Sharon L., Crouch, Simon, Care, Matthew A., Worrillow, Lisa, Smith, Alex, Patmore, Russell, Westhead, David R., Tooze, Reuben, Roman, Eve, Jack, Andrew S
Published in British journal of haematology (01.11.2012)
Published in British journal of haematology (01.11.2012)
Get full text
Journal Article
Spontaneous EBV-Reactivation during B Cell Differentiation as a Model for Polymorphic EBV-Driven Lymphoproliferation
Care, Matthew A, Stephenson, Sophie, Owen, Roger, Doody, Gina M, Tooze, Reuben M
Published in Cancers (07.06.2023)
Published in Cancers (07.06.2023)
Get full text
Journal Article
Comparative analysis of gene expression platforms for cell‐of‐origin classification of diffuse large B‐cell lymphoma shows high concordance
Ahmed, Sophia, Glover, Paul, Taylor, Jan, Sha, Chulin, Care, Matthew A., Tooze, Reuben, Davies, Andrew, Westhead, David R., Johnson, Peter W. M., Burton, Catherine, Barrans, Sharon L.
Published in British journal of haematology (01.02.2021)
Published in British journal of haematology (01.02.2021)
Get full text
Journal Article