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Perry, Rachel J, Rabin-Court, Aviva, Song, Joongyu D, Cardone, Rebecca L, Wang, Yongliang, Kibbey, Richard G, Shulman, Gerald I
Published in Nature communications (01.02.2019)
Published in Nature communications (01.02.2019)
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Multi-Tissue Acceleration of the Mitochondrial Phosphoenolpyruvate Cycle Improves Whole-Body Metabolic Health
Abulizi, Abudukadier, Cardone, Rebecca L., Stark, Romana, Lewandowski, Sophie L., Zhao, Xiaojian, Hillion, Joelle, Ma, Lingjun, Sehgal, Raghav, Alves, Tiago C., Thomas, Craig, Kung, Charles, Wang, Bei, Siebel, Stephan, Andrews, Zane B., Mason, Graeme F., Rinehart, Jesse, Merrins, Matthew J., Kibbey, Richard G.
Published in Cell metabolism (03.11.2020)
Published in Cell metabolism (03.11.2020)
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Dyrk1b promotes hepatic lipogenesis by bypassing canonical insulin signaling and directly activating mTORC2 in mice
Bhat, Neha, Narayanan, Anand, Fathzadeh, Mohsen, Kahn, Mario, Zhang, Dongyan, Goedeke, Leigh, Neogi, Arpita, Cardone, Rebecca L, Kibbey, Richard G, Fernandez-Hernando, Carlos, Ginsberg, Henry N, Jain, Dhanpat, Shulman, Gerald I, Mani, Arya
Published in The Journal of clinical investigation (01.02.2022)
Published in The Journal of clinical investigation (01.02.2022)
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Imeglimin lowers glucose primarily by amplifying glucose-stimulated insulin secretion in high-fat-fed rodents
Perry, Rachel J, Cardone, Rebecca L, Petersen, Max C, Zhang, Dongyan, Fouqueray, Pascale, Hallakou-Bozec, Sophie, Bolze, Sébastien, Shulman, Gerald I, Petersen, Kitt Falk, Kibbey, Richard G
Published in American journal of physiology: endocrinology and metabolism (01.08.2016)
Published in American journal of physiology: endocrinology and metabolism (01.08.2016)
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β-cell deletion of the PKm1 and PKm2 isoforms of pyruvate kinase in mice reveals their essential role as nutrient sensors for the KATP channel
Foster, Hannah R, Ho, Thuong, Potapenko, Evgeniy, Sdao, Sophia M, Huang, Shih Ming, Lewandowski, Sophie L, VanDeusen, Halena R, Davidson, Shawn M, Cardone, Rebecca L, Prentki, Marc, Kibbey, Richard G, Merrins, Matthew J
Published in eLife (23.08.2022)
Published in eLife (23.08.2022)
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Mitochondrial GTP Links Nutrient Sensing to β Cell Health, Mitochondrial Morphology, and Insulin Secretion Independent of OxPhos
Jesinkey, Sean R., Madiraju, Anila K., Alves, Tiago C., Yarborough, OrLando H., Cardone, Rebecca L., Zhao, Xiaojian, Parsaei, Yassmin, Nasiri, Ali R., Butrico, Gina, Liu, Xinran, Molina, Anthony J., Rountree, Austin M., Neal, Adam S., Wolf, Dane M., Sterpka, John, Philbrick, William M., Sweet, Ian R., Shirihai, Orian H., Kibbey, Richard G.
Published in Cell reports (Cambridge) (16.07.2019)
Published in Cell reports (Cambridge) (16.07.2019)
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AKT1(E17K) in human solid tumours
Bleeker, F E, Felicioni, L, Buttitta, F, Lamba, S, Cardone, L, Rodolfo, M, Scarpa, A, Leenstra, S, Frattini, M, Barbareschi, M, Grammastro, M Del, Sciarrotta, M G, Zanon, C, Marchetti, A, Bardelli, A
Published in Oncogene (18.09.2008)
Published in Oncogene (18.09.2008)
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Journal Article
Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production
Gassaway, Brandon M., Cardone, Rebecca L., Padyana, Anil K., Petersen, Max C., Judd, Evan T., Hayes, Sebastian, Tong, Shuilong, Barber, Karl W., Apostolidi, Maria, Abulizi, Abudukadier, Sheetz, Joshua B., Kshitiz, Aerni, Hans R., Gross, Stefan, Kung, Charles, Samuel, Varman T., Shulman, Gerald I., Kibbey, Richard G., Rinehart, Jesse
Published in Cell reports (Cambridge) (10.12.2019)
Published in Cell reports (Cambridge) (10.12.2019)
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708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits
THOMSON, P. A, PARLA, J. S, CASS, S, GHIBAN, E, USAHENNAH, W, EVANS, K. L, REBOLINI, D, MILLAR, J. K, HARRIS, S. E, STARR, J. M, MACLNTYRE, D. J, SCOTLAND, Generation, MCRAE, A. F, MCINTOSH, A. M, WATSON, J. D, DEARY, I. J, VISSCHER, P. M, BLACKWOOD, D. H, MCCOMBIE, W. R, PORTEOUS, D. J, KRAMER, M, RAMAKRISHNAN, K, YAO, J, SOARES, D. C, MCCARTHY, S, MORRIS, S. W, CARDONE, L
Published in Molecular psychiatry (01.06.2014)
Published in Molecular psychiatry (01.06.2014)
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An innovative Strategy to Quickly Grade Functional Test Programs
Angione, F., Bernardi, P., Calabrese, A., Cardone, L., Niccoletti, A., Piumatti, D., Quer, S., Appello, D., Tancorre, V., Ugioli, R.
Published in 2022 IEEE International Test Conference (ITC) (01.09.2022)
Published in 2022 IEEE International Test Conference (ITC) (01.09.2022)
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Conference Proceeding
Loss of ZNF148 enhances insulin secretion in human pancreatic β cells
de Klerk, Eleonora, Xiao, Yini, Emfinger, Christopher H, Keller, Mark P, Berrios, David I, Loconte, Valentina, Ekman, Axel A, White, Kate L, Cardone, Rebecca L, Kibbey, Richard G, Attie, Alan D, Hebrok, Matthias
Published in JCI insight (08.06.2023)
Published in JCI insight (08.06.2023)
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Journal Article
Acetate mediates a microbiome-brain-β-cell axis to promote metabolic syndrome
Perry, Rachel J, Peng, Liang, Barry, Natasha A, Cline, Gary W, Zhang, Dongyan, Cardone, Rebecca L, Petersen, Kitt Falk, Kibbey, Richard G, Goodman, Andrew L, Shulman, Gerald I
Published in Nature (London) (09.06.2016)
Published in Nature (London) (09.06.2016)
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Journal Article
β Cell-specific deletion of Zfp148 improves nutrient-stimulated β cell Ca2+ responses
Emfinger, Christopher H, de Klerk, Eleonora, Schueler, Kathryn L, Rabaglia, Mary E, Stapleton, Donnie S, Simonett, Shane P, Mitok, Kelly A, Wang, Ziyue, Liu, Xinyue, Paulo, Joao A, Yu, Qinq, Cardone, Rebecca L, Foster, Hannah R, Lewandowski, Sophie L, Perales, José C, Kendziorski, Christina M, Gygi, Steven P, Kibbey, Richard G, Keller, Mark P, Hebrok, Matthias, Merrins, Matthew J, Attie, Alan D
Published in JCI insight (23.05.2022)
Published in JCI insight (23.05.2022)
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Journal Article
Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis
Davis, Jeffrey C., Alves, Tiago C., Helman, Aharon, Chen, Jonathan C., Kenty, Jennifer H., Cardone, Rebecca L., Liu, David R., Kibbey, Richard G., Melton, Douglas A.
Published in Cell reports (Cambridge) (12.05.2020)
Published in Cell reports (Cambridge) (12.05.2020)
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316-OR: Genetic Deletion of Beta-Cell Pkm1, Pkm2, and Pck2 Identifies PEP as an Essential Signal for Compartmentalized KATP Closure and Cycling of the Insulin Secretory Pathway
FOSTER, HANNAH R., HO, THUONG, POTAPENKO, EVGENIY, CARDONE, REBECCA L., KIBBEY, RICHARD, MERRINS, MATTHEW J.
Published in Diabetes (New York, N.Y.) (01.06.2022)
Published in Diabetes (New York, N.Y.) (01.06.2022)
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N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis
Grevengoed, Trisha J., Trammell, Samuel A. J., McKinney, Michele K., Petersen, Natalia, Cardone, Rebecca L., Svenningsen, Jens S., Ogasawara, Daisuke, Nexøe-Larsen, Christina C., Knop, Filip K., Schwartz, Thue W., Kibbey, Richard G., Cravatt, Benjamin F., Gillum, Matthew P.
Published in Proceedings of the National Academy of Sciences - PNAS (03.12.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (03.12.2019)
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Journal Article
β-cell deletion of the PKm1 and PKm2 isoforms of pyruvate kinase in mice reveals their essential role as nutrient sensors for the K ATP channel
Foster, Hannah R, Ho, Thuong, Potapenko, Evgeniy, Sdao, Sophia M, Huang, Shih Ming, Lewandowski, Sophie L, VanDeusen, Halena R, Davidson, Shawn M, Cardone, Rebecca L, Prentki, Marc, Kibbey, Richard G, Merrins, Matthew J
Published in eLife (23.08.2022)
Published in eLife (23.08.2022)
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127-OR: In Vivo Genetic Evidence That the Pyruvate Kinase Isoforms PKM1 and PKM2 Differentially Control Beta-Cell Fuel Sensing
FOSTER, HANNAH R., HO, THUONG, POTAPENKO, EVGENIY, LEWANDOWSKI, SOPHIE L., SDAO, SOPHIA, VANDEUSEN, HALENA R., CARDONE, REBECCA L., KIBBEY, RICHARD, MERRINS, MATTHEW J.
Published in Diabetes (New York, N.Y.) (01.06.2021)
Published in Diabetes (New York, N.Y.) (01.06.2021)
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369-OR: [1,2-13C2]-L-Glutamine Mass Isotopomers Map Hepatic Mitochondrial Metabolism without Tracer Interference
SIEBEL, STEPHAN, CARDONE, REBECCA L., ABULIZI, ABUDUKADIER, RAAISA, RAAISA, WILLIAMS, RICHARD M., SEHGAL, RAGHAV, BUTRICO, GINA MARIE, CLINE, GARY, ROTHMAN, DOUGLAS L., MASON, GRAEME F., KIBBEY, RICHARD
Published in Diabetes (New York, N.Y.) (01.06.2020)
Published in Diabetes (New York, N.Y.) (01.06.2020)
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