Oncogenic Genomic Alterations, Clinical Phenotypes, and Outcomes in Metastatic Castration-Sensitive Prostate Cancer
Stopsack, Konrad H, Nandakumar, Subhiksha, Wibmer, Andreas G, Haywood, Samuel, Weg, Emily S, Barnett, Ethan S, Kim, Chloe J, Carbone, Emily A, Vasselman, Samantha E, Nguyen, Bastien, Hullings, Melanie A, Scher, Howard I, Morris, Michael J, Solit, David B, Schultz, Nikolaus, Kantoff, Philip W, Abida, Wassim
Published in Clinical cancer research (01.07.2020)
Published in Clinical cancer research (01.07.2020)
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Journal Article
Clinical Utility of the Nuclear-localized AR-V7 Biomarker in Circulating Tumor Cells in Improving Physician Treatment Choice in Castration-resistant Prostate Cancer
Graf, Ryon P., Hullings, Melanie, Barnett, Ethan S., Carbone, Emily, Dittamore, Ryan, Scher, Howard I.
Published in European urology (01.02.2020)
Published in European urology (01.02.2020)
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Analysis of the Prevalence of Microsatellite Instability in Prostate Cancer and Response to Immune Checkpoint Blockade
Abida, Wassim, Cheng, Michael L, Armenia, Joshua, Middha, Sumit, Autio, Karen A, Vargas, Hebert Alberto, Rathkopf, Dana, Morris, Michael J, Danila, Daniel C, Slovin, Susan F, Carbone, Emily, Barnett, Ethan S, Hullings, Melanie, Hechtman, Jaclyn F, Zehir, Ahmet, Shia, Jinru, Jonsson, Philip, Stadler, Zsofia K, Srinivasan, Preethi, Laudone, Vincent P, Reuter, Victor, Wolchok, Jedd D, Socci, Nicholas D, Taylor, Barry S, Berger, Michael F, Kantoff, Philip W, Sawyers, Charles L, Schultz, Nikolaus, Solit, David B, Gopalan, Anuradha, Scher, Howard I
Published in JAMA oncology (01.04.2019)
Published in JAMA oncology (01.04.2019)
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Journal Article
Morphology-Predicted Large-Scale Transition Number in Circulating Tumor Cells Identifies a Chromosomal Instability Biomarker Associated with Poor Outcome in Castration-Resistant Prostate Cancer
Schonhoft, Joseph D, Zhao, Jimmy L, Jendrisak, Adam, Carbone, Emily A, Barnett, Ethan S, Hullings, Melanie A, Gill, Audrey, Sutton, Ramsay, Lee, Jerry, Dago, Angel E, Landers, Mark, Bakhoum, Samuel F, Wang, Yipeng, Gonen, Mithat, Dittamore, Ryan, Scher, Howard I
Published in Cancer research (Chicago, Ill.) (15.11.2020)
Published in Cancer research (Chicago, Ill.) (15.11.2020)
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Journal Article
Analysis of BRCA2 Copy Number Loss and Genomic Instability in Circulating Tumor Cells from Patients with Metastatic Castration-resistant Prostate Cancer
Barnett, Ethan S., Schultz, Nikolaus, Stopsack, Konrad H., Lam, Ernest T., Arfe, Andrea, Lee, Jerry, Zhao, Jimmy L., Schonhoft, Joseph D., Carbone, Emily A., Keegan, Niamh M., Wibmer, Andreas, Wang, Yipeng, Solit, David B., Abida, Wassim, Wenstrup, Richard, Scher, Howard I.
Published in European urology (01.02.2023)
Published in European urology (01.02.2023)
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Journal Article
Circulating Tumor Cell Chromosomal Instability and Neuroendocrine Phenotype by Immunomorphology and Poor Outcomes in Men with mCRPC Treated with Abiraterone or Enzalutamide
Brown, Landon C, Halabi, Susan, Schonhoft, Joseph D, Yang, Qian, Luo, Jun, Nanus, David M, Giannakakou, Paraskevi, Szmulewitz, Russell Z, Danila, Daniel C, Barnett, Ethan S, Carbone, Emily A, Zhao, Jimmy L, Healy, Patrick, Anand, Monika, Gill, Audrey, Jendrisak, Adam, Berry, William R, Gupta, Santosh, Gregory, Simon G, Wenstrup, Richard, Antonarakis, Emmanuel S, George, Daniel J, Scher, Howard I, Armstrong, Andrew J
Published in Clinical cancer research (15.07.2021)
Published in Clinical cancer research (15.07.2021)
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Journal Article
Clinical annotations for prostate cancer research: Defining data elements, creating a reproducible analytical pipeline, and assessing data quality
Keegan, Niamh M., Vasselman, Samantha E., Barnett, Ethan S., Nweji, Barbara, Carbone, Emily A., Blum, Alexander, Morris, Michael J., Rathkopf, Dana E., Slovin, Susan F., Danila, Daniel C., Autio, Karen A., Scher, Howard I., Kantoff, Philip W., Abida, Wassim, Stopsack, Konrad H.
Published in The Prostate (01.08.2022)
Published in The Prostate (01.08.2022)
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Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) mouse model
Ferro, Austin, Carbone, Emily, Zhang, Jenny, Marzouk, Evan, Villegas, Monica, Siegel, Asher, Nguyen, Donna, Possidente, Thomas, Hartman, Jessilyn, Polley, Kailen, Ingram, Melissa A, Berry, Georgia, Reynolds, Thomas H, Possidente, Bernard, Frederick, Kimberley, Ives, Stephen, Lagalwar, Sarita
Published in PloS one (06.12.2017)
Published in PloS one (06.12.2017)
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Assessing the reliability and validity of direct observation and traffic camera streams to measure helmet and motorcycle use
Zaccaro, Heather N, Carbone, Emily C, Dsouza, Nishita, Xu, Michelle R, Byrne, Mary C, Kraemer, John D
Published in Injury prevention (01.12.2015)
Published in Injury prevention (01.12.2015)
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Development of an immunofluorescent AR-V7 circulating tumor cell assay - A blood-based test for men with metastatic prostate cancer
Lu, David, Krupa, Rachel, Harvey, Melissa, Graf, Ryon P, Schreiber, Nicole, Barnett, Ethan, Carbone, Emily, Jendrisak, Adam, Gill, Audrey, Orr, Sarah, Scher, Howard I, Schonhoft, Joseph D
Published in Journal of circulating biomarkers (2020)
Published in Journal of circulating biomarkers (2020)
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Journal Article
Genomic alterations and evolution in patients with prostate cancer with histologic evidence of neuroendocrine differentiation
Barnett, Ethan, Carbone, Emily, Keegan, Niamh M., Vasselman, Samantha E, Nweji, Barbara, Zaidi, Samir, Scher, Howard I.
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article
Analysis of androgen receptor dynamics through immunofluorescent staining of circulating tumor cells in castration-resistant prostate cancer
Barnett, Ethan, Gupta, Santosh, Erazo, Tatiana, Lam, Ernest, Carbone, Emily, Zanone, Michelle, Nystrom, Lucy, Gajar, Ria N, Wenstrup, Rick, Scher, Howard I.
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
Automated analysis of FDG-PET/CT imaging to monitor heterogeneous disease response in metastatic castration-resistant prostate cancer
Barnett, Ethan, Woo, Sungmin, Perk, Timothy G., Munian-Govindan, Rajkumar, Lokre, Ojaswita, Gajar, Ria N, Erazo, Tatiana, Carbone, Emily, Morris, Michael J., Vargas, Hebert Alberto, Scher, Howard I.
Published in Journal of clinical oncology (20.02.2023)
Published in Journal of clinical oncology (20.02.2023)
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Journal Article
Chromosomal instability (CIN) in circulating tumor cells (CTC) predicts for taxane sensitivity in metastatic castration-resistant prostate cancer (mCRPC)
Keegan, Niamh M., Arfe, Andrea, Barnett, Ethan, Cohn, Erica Dayan, Zhao, Jimmy, Carbone, Emily, Zanone, Michelle, Anderson, Amanda, Wenstrup, Rick, Scher, Howard I.
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article
Clinical annotations for prostate cancer research: Defining data elements, creating a reproducible analytical pipeline, and assessing data quality
Keegan, Niamh M., Vasselman, Samantha E, Barnett, Ethan, Nweji, Barbara, Carbone, Emily, Blum, Alexander, Morris, Michael J., Rathkopf, Dana E., Slovin, Susan F., Danila, Daniel Costin, Autio, Karen A., Scher, Howard I., Kantoff, Philip W., Abida, Wassim, Stopsack, Konrad H.
Published in Journal of clinical oncology (20.02.2022)
Published in Journal of clinical oncology (20.02.2022)
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Journal Article
Circulating tumor cells (CTCs) with small-cell like pathology are prevalent in metastatic castration-resistant prostate cancer (mCRPC) and show selective pharmacodynamic reductions in patients treated with platinum but not ARSI or taxane
Scher, Howard I., Jendrisak, Adam, Gill, Audrey, Barnett, Ethan, Gopalan, Anuradha, Zaidi, Samir, Benoliel, Hannah, Carbone, Emily, Byun, Jiyun, Schonhoft, Joseph, Wenstrup, Rick
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
Clinical significance of CTC enumeration on the Epic Sciences platform in metastatic castration-resistant prostate cancer (mCRPC) patients treated with AR signaling inhibitors (ARSi)
Schonhoft, Joseph, Gill, Audrey, Graf, Ryon P, Jendrisak, Adam, Barnett, Ethan, Benoliel, Hannah, Carbone, Emily, Tubbs, Alisa, Orr, Sarah, Byun, Jiyun, Wenstrup, Rick, Scher, Howard I.
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
Abstract 463: Features consistent with a small-cell neuroendocrine like (SC/NE-L) transformation can be readily detected and quantified in circulating tumor cells (CTCs)
Scher, Howard I., Jendrisak, Adam, Gilbertson, Cole, Gill, Audrey, Barnett, Ethan, Gopalan, Anuradha, Keegan, Niamh, Zaidi, Samir, Benoliel, Hannah, Emily, Carbone, Wang, Eva, Lu, James, Tubbs, Alisa, Anderson, Amanda, Jones, Joshua, Schonhoft, Joseph D., Wenstrup, Rick
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Schlafen 11 (SLFN11), a putative predictive biomarker of platinum/PARPi response, is frequently detected on circulating tumor cells (CTCs) in advanced prostate cancer
Scher, Howard I., Fernandez, Luisa, Cunningham, Kate, Elphick, Natalie, Barnett, Ethan, Lee, Jerry, Gilbertson, Cole, Carbone, Emily, Bourdon, David, Blankfard, Martin, Wang, Eva, Jones, Joshua Timothy, Tubbs, Alisa, Anderson, Amanda, Schonhoft, Joseph D., Wenstrup, Rick
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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Journal Article
Morphology-predicted, large-scale transition (LST) number in circulating tumor cells (CTC) as a biomarker of chromosomal instability (CIN) to assess early resistance to standard of care (SOC) drugs in mCRPC
Scher, Howard I., Schonhoft, Joseph, Hullings, Melanie, Carbone, Emily, Barnett, Ethan, Sutton, Ramsay, Jendrisak, Adam, Landers, Mark Andrew, Wang, Yipeng, Dittamore, Ryan
Published in Journal of clinical oncology (01.03.2019)
Published in Journal of clinical oncology (01.03.2019)
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