GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis
Littlewood-Evans, Amanda, Sarret, Sophie, Apfel, Verena, Loesle, Perrine, Dawson, Janet, Zhang, Juan, Muller, Alban, Tigani, Bruno, Kneuer, Rainer, Patel, Saijel, Valeaux, Stephanie, Gommermann, Nina, Rubic-Schneider, Tina, Junt, Tobias, Carballido, José M
Published in The Journal of experimental medicine (22.08.2016)
Published in The Journal of experimental medicine (22.08.2016)
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Triggering the succinate receptor GPR91 on dendritic cells enhances immunity
Mao, Xiaohong, Voshol, Hans, Werner, Gudrun, Rot, Antal, Rubic, Tina, Lametschwandtner, Günther, Kund, Julia, Carballido, José M, Meingassner, Josef G, Jost, Sandra, Junt, Tobias, Carballido-Perrig, Nicole, Hinteregger, Sonja, Schwärzler, Christoph
Published in Nature immunology (01.11.2008)
Published in Nature immunology (01.11.2008)
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G‑Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5) Agonists Reduce the Production of Proinflammatory Cytokines and Stabilize the Alternative Macrophage Phenotype
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Published in Journal of medicinal chemistry (26.12.2014)
Published in Journal of medicinal chemistry (26.12.2014)
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Innate acting memory Th1 cells modulate heterologous diseases
Rakebrandt, Nikolas, Yassini, Nima, Kolz, Anna, Schorer, Michelle, Lambert, Katharina, Goljat, Eva, Estrada Brull, Anna, Rauld, Celine, Balazs, Zsolt, Krauthammer, Michael, Carballido, José M, Peters, Anneli, Joller, Nicole
Published in Proceedings of the National Academy of Sciences - PNAS (11.06.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (11.06.2024)
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A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia
Suply, Thomas, Hannedouche, Sébastien, Carte, Nathalie, Li, Jianping, Grosshans, Bianka, Schaefer, Michael, Raad, Layla, Beck, Valérie, Vidal, Solange, Hiou-Feige, Agnès, Beluch, Noémie, Barbieri, Samuel, Wirsching, Johann, Lageyre, Nadine, Hillger, Frank, Debon, Corinne, Dawson, Janet, Smith, Philip, Lannoy, Vincent, Detheux, Michel, Bitsch, Francis, Falchetto, Rocco, Bouwmeester, Tewis, Porter, Jeffrey, Baumgarten, Birgit, Mansfield, Keith, Carballido, José M, Seuwen, Klaus, Bassilana, Frédéric
Published in Science signaling (12.09.2017)
Published in Science signaling (12.09.2017)
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Secukinumab for the treatment of psoriasis, psoriatic arthritis, and axial spondyloarthritis: Physical and pharmacological properties underlie the observed clinical efficacy and safety
Kolbinger, Frank, Di Padova, Franco, Deodhar, Atul, Hawkes, Jason E., Huppertz, Christine, Kuiper, Torsten, McInnes, Iain B., Ritchlin, Christopher T., Rosmarin, David, Schett, Georg, Carballido, José M., Häusermann, Peter, Calonder, Claudio, Vogel, Beate, Rondeau, Jean-Michel, Bruin, Gerard
Published in Pharmacology & therapeutics (Oxford) (01.01.2022)
Published in Pharmacology & therapeutics (Oxford) (01.01.2022)
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The Emerging Jamboree of Transformative Therapies for Autoimmune Diseases
Carballido, José M, Regairaz, Camille, Rauld, Celine, Raad, Layla, Picard, Damien, Kammüller, Michael
Published in Frontiers in immunology (31.03.2020)
Published in Frontiers in immunology (31.03.2020)
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Overcoming Obstacles in the Development of Antigen-Specific Immunotherapies for Type 1 Diabetes
Thomas, Ranjeny, Carballido, José M, Wesley, Johnna D, Ahmed, Simi T
Published in Frontiers in immunology (05.08.2021)
Published in Frontiers in immunology (05.08.2021)
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Host succinate inhibits influenza virus infection through succinylation and nuclear retention of the viral nucleoprotein
Guillon, Antoine, Brea‐Diakite, Deborah, Cezard, Adeline, Wacquiez, Alan, Baranek, Thomas, Bourgeais, Jérôme, Picou, Frédéric, Vasseur, Virginie, Meyer, Léa, Chevalier, Christophe, Auvet, Adrien, Carballido, José M, Nadal Desbarats, Lydie, Dingli, Florent, Turtoi, Andrei, Le Gouellec, Audrey, Fauvelle, Florence, Donchet, Amélie, Crépin, Thibaut, Hiemstra, Pieter S, Paget, Christophe, Loew, Damarys, Herault, Olivier, Naffakh, Nadia, Le Goffic, Ronan, Si‐Tahar, Mustapha
Published in The EMBO journal (14.06.2022)
Published in The EMBO journal (14.06.2022)
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Identification of a SIRT1 Mutation in a Family with Type 1 Diabetes
Biason-Lauber, Anna, Böni-Schnetzler, Marianne, Hubbard, Basil P., Bouzakri, Karim, Brunner, Andrea, Cavelti-Weder, Claudia, Keller, Cornelia, Meyer-Böni, Monika, Meier, Daniel T., Brorsson, Caroline, Timper, Katharina, Leibowitz, Gil, Patrignani, Andrea, Bruggmann, Remy, Boily, Gino, Zulewski, Henryk, Geier, Andreas, Cermak, Jennifer M., Elliott, Peter, Ellis, James L., Westphal, Christoph, Knobel, Urs, Eloranta, Jyrki J., Kerr-Conte, Julie, Pattou, François, Konrad, Daniel, Matter, Christian M., Fontana, Adriano, Rogler, Gerhard, Schlapbach, Ralph, Regairaz, Camille, Carballido, José M., Glaser, Benjamin, McBurney, Michael W., Pociot, Flemming, Sinclair, David A., Donath, Marc Y.
Published in Cell metabolism (05.03.2013)
Published in Cell metabolism (05.03.2013)
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Effect of ofatumumab on pregnancy, parturition, and lactation in cynomolgus monkeys
Bellot, Muriel, Luetjens, C. Marc, Bagger, Morten, Horvath, Courtney, Sutter, Esther, DeLise, Anthony, Brees, Dominique, Carballido, José M., Pingili, Ratnakar, Ramanathan, Krishnan, Kieseier, Bernd C., Hellwig, Kerstin
Published in Reproductive toxicology (Elmsford, N.Y.) (01.03.2022)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.03.2022)
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The T‐cell fingerprint of MALT1 paracaspase revealed by selective inhibition
Bardet, Maureen, Unterreiner, Adeline, Malinverni, Claire, Lafossas, Frédérique, Vedrine, Corinne, Boesch, Danielle, Kolb, Yeter, Kaiser, Daniel, Glück, Anton, Schneider, Martin A, Katopodis, Andreas, Renatus, Martin, Simic, Oliver, Schlapbach, Achim, Quancard, Jean, Régnier, Catherine H, Bold, Guido, Pissot‐Soldermann, Carole, Carballido, José M, Kovarik, Jiri, Calzascia, Thomas, Bornancin, Frédéric
Published in Immunology and cell biology (01.01.2018)
Published in Immunology and cell biology (01.01.2018)
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Imaging Mass Cytometry and Single-Cell Genomics Reveal Differential Depletion and Repletion of B-Cell Populations Following Ofatumumab Treatment in Cynomolgus Monkeys
Theil, Diethilde, Smith, Paul, Huck, Catherine, Gilbart, Yoann, Kakarieka, Algirdas, Leppert, David, Rauld, Celine, Schmid, Cindy, Baumgartner, Reto, Stuber, Nathalie, Cordoba, Francisco, Dubost, Valerie, Darribat, Katy, Jivkov, Magali, Frieauff, Wilfried, Kneuer, Rainer, Stoeckli, Markus, Reinker, Stefan, Mansfield, Keith, Carballido, José M, Couttet, Philippe, Weckbecker, Gisbert
Published in Frontiers in immunology (20.06.2019)
Published in Frontiers in immunology (20.06.2019)
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Mass Cytometry of CSF Identifies an MS-Associated B-cell Population
Johansson, David, Rauld, Céline, Roux, Julien, Regairaz, Camille, Galli, Edoardo, Callegari, Ilaria, Raad, Layla, Waldt, Annick, Cuttat, Rachel, Roma, Guglielmo, Diebold, Martin, Becher, Burkhard, Kuhle, Jens, Derfuss, Tobias, Carballido, José M, Sanderson, Nicholas S R
Published in Neurology : neuroimmunology & neuroinflammation (01.03.2021)
Published in Neurology : neuroimmunology & neuroinflammation (01.03.2021)
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Metabolic and immunomodulatory control of type 1 diabetes via orally delivered bile-acid-polymer nanocarriers of insulin or rapamycin
Lee, Jung Seok, Han, Patrick, Chaudhury, Rabib, Khan, Shihan, Bickerton, Sean, McHugh, Michael D., Park, Hyun Bong, Siefert, Alyssa L., Rea, Gerald, Carballido, José M., Horwitz, David A., Criscione, Jason, Perica, Karlo, Samstein, Robert, Ragheb, Ragy, Kim, Dongin, Fahmy, Tarek M.
Published in Nature biomedical engineering (01.09.2021)
Published in Nature biomedical engineering (01.09.2021)
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The aryl hydrocarbon receptor (AhR) ligand VAF347 selectively acts on monocytes and naïve CD4+ Th cells to promote the development of IL-22-secreting Th cells
Baba, Nobuyasu, Rubio, Manuel, Kenins, Linda, Regairaz, Camille, Woisetschlager, Maximilian, Carballido, José M, Sarfati, Marika
Published in Human immunology (01.08.2012)
Published in Human immunology (01.08.2012)
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Succinate causes pathological cardiomyocyte hypertrophy through GPR91 activation
Aguiar, Carla J, Rocha-Franco, João A, Sousa, Pedro A, Santos, Anderson K, Ladeira, Marina, Rocha-Resende, Cibele, Ladeira, Luiz O, Resende, Rodrigo R, Botoni, Fernando A, Barrouin Melo, Marcos, Lima, Cristiano X, Carballido, José M, Cunha, Thiago M, Menezes, Gustavo B, Guatimosim, Silvia, Leite, M Fatima
Published in Cell communication and signaling (24.12.2014)
Published in Cell communication and signaling (24.12.2014)
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