Search Results - "Caprathe, B." :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

2-Amino-4H-3,1-benzoxazin-4-ones as Inhibitors of C1r Serine Protease

2-Amino-4H-3,1-benzoxazin-4-ones as Inhibitors of C1r Serine Protease

by Hays, Sheryl J, Caprathe, Bradley W, Gilmore, John L, Amin, Nilam, Emmerling, Mark R, Michael, Walter, Nadimpalli, Ravi, Nath, Rathna, Raser, Kadee J, Stafford, Daniel, Watson, Desiree, Wang, Kevin, Jaen, Juan C
Published in Journal of medicinal chemistry (26.03.1998)

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Design and Synthesis of m1-Selective Muscarinic Agonists: (R)-(−)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3‘-Methoxyphenyl)-2-propynyl)- oxime Maleate (CI-1017), a Functionally m1-Selective Muscarinic Agonist

Design and Synthesis of m1-Selective Muscarinic Agonists: (R)-(−)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3‘-Methoxyphenyl)-2-propynyl)- oxime Maleate (CI-1017), a Functionally m1-Selective Muscarinic Agonist

by Tecle, Haile, Barrett, Stephen D, Lauffer, David J, Augelli-Szafran, Corinne, Brann, Mark R, Callahan, Michael J, Caprathe, Bradley. W, Davis, Robert E, Doyle, Patricia D, Eubanks, David, Lipiniski, William, Mirzadegan, Tara, Moos, Walter H, Moreland, D. W, Nelson, Carrie B, Pavia, Michael R, Raby, Charlotte, Schwarz, Roy D, Spencer, Carolyn J, Thomas, Anthony J, Jaen, Juan C
Published in Journal of medicinal chemistry (02.07.1998)

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Kynurenic Acid Derivatives Inhibit the Binding of Nerve Growth Factor (NGF) to the Low-Affinity p75 NGF Receptor

Kynurenic Acid Derivatives Inhibit the Binding of Nerve Growth Factor (NGF) to the Low-Affinity p75 NGF Receptor

by Jaen, Juan C, Laborde, Edgardo, Bucsh, Ruth A, Caprathe, Bradley W, Sorenson, Roderick J, Fergus, James, Spiegel, Katharyn, Marks, James, Dickerson, Melvin R, Davis, Robert E
Published in Journal of medicinal chemistry (01.10.1995)

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Evaluation of the effects of the enantiomers of reduced haloperidol, azaperol, and related 4-amino-1-arylbutanols on dopamine and .sigma. receptors

Evaluation of the effects of the enantiomers of reduced haloperidol, azaperol, and related 4-amino-1-arylbutanols on dopamine and .sigma. receptors

by Jaen, Juan C, Caprathe, Bradley W, Pugsley, Thomas A, Wise, Lawrence D, Akunne, Hyacinth
Published in Journal of medicinal chemistry (26.11.1993)

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Identification of a 3-Hydroxylated Tacrine Metabolite in Rat and Man: Metabolic Profiling Implications and Pharmacology

Identification of a 3-Hydroxylated Tacrine Metabolite in Rat and Man: Metabolic Profiling Implications and Pharmacology

by Pool, William F, Woolf, Thomas F, Reily, Michael D, Caprathe, Bradley W, Emmerling, Mark R, Jaen, Juan C
Published in Journal of medicinal chemistry (19.07.1996)

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4-(1,2,5,6-Tetrahydro-1-alkyl-3-pyridinyl)-2-thiazolamines: a novel class of compounds with central dopamine agonist properties

4-(1,2,5,6-Tetrahydro-1-alkyl-3-pyridinyl)-2-thiazolamines: a novel class of compounds with central dopamine agonist properties

by Jaen, Juan C, Wise, Lawrence D, Caprathe, Bradley W, Tecle, Haile, Bergmeier, Stephen, Humblet, Christine C, Heffner, Thomas G, Meltzer, Leonard T, Pugsley, Thomas A
Published in Journal of medicinal chemistry (01.01.1990)

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The Discovery and Structure-Activity Relationships of 1,2,3,6-Tetrahydro-4-phenyl-1-[(arylcyclohexenyl)alkyl]pyridines. Dopamine Autoreceptor Agonists and Potential Antipsychotic Agents

The Discovery and Structure-Activity Relationships of 1,2,3,6-Tetrahydro-4-phenyl-1-[(arylcyclohexenyl)alkyl]pyridines. Dopamine Autoreceptor Agonists and Potential Antipsychotic Agents

by Wright, Jon L, Caprathe, Bradley W, Downing, Dennis M, Glase, Shelly A, Heffner, Thomas G, Jaen, Juan C, Johnson, Stephen J, Kesten, Suzanne R, MacKenzie, Robert G
Published in Journal of medicinal chemistry (01.10.1994)

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Pharmacological profile of the dopamine partial agonist, (+/-)-PD 128483 and its enantiomers

by MELTZER, L. T, CAPRATHE, B. W, WILEY, J. N, WISE, L. D, HEFFNER, T. G, CHRISTOFFERSEN, C. L, CORBIN, A. E, JAEN, J. C, NINTEMAN, F. W, PUGSLEY, T. A, SERPA, K. A, SHIH, Y.-H, WHETZEL, S. Z
Published in The Journal of pharmacology and experimental therapeutics (01.09.1993)

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Synthesis of the enantiomers of reduced haloperidol

Synthesis of the enantiomers of reduced haloperidol

by Jaen, J C, Caprathe, B W, Priebe, S, Wise, L D
Published in Pharmaceutical research (01.08.1991)

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CI-1017, a functionally M1-selective muscarinic agonist: design, synthesis, and preclinical pharmacology

CI-1017, a functionally M1-selective muscarinic agonist: design, synthesis, and preclinical pharmacology

by Tecle, H, Schwarz, R.D, Barrett, S.D, Callahan, M.J, Caprathe, B.W, Davis, R.E, Doyle, P, Emmerling, M, Lauffer, D.J, Mirzadegan, T, Moreland, D.W, Lipiniski, W, Nelson, C, Raby, C, Spencer, C, Spiegel, K, Thomas, A.J, Jaen, J.C
Published in Pharmaceutica acta Helvetiae (01.03.2000)

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Amnesia-reversal activity of a series of cyclic imides

Amnesia-reversal activity of a series of cyclic imides

by Butler, Donald E, Leonard, James D, Caprathe, Bradley W, L'Italien, Yvon J, Pavia, Michael R, Hershenson, Fred M, Poschel, Paul H, Marriott, John G
Published in Journal of medicinal chemistry (01.03.1987)

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Chemical purity and mutagenicity: Case study of a drug in development

Chemical purity and mutagenicity: Case study of a drug in development

by Kropko, M.L., Jaen, J.C., Theiss, J.C., Wold, S., Caprathe, B.W., Wise, L.D.
Published in Mutation research (01.04.1992)

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Dopamine autoreceptor agonists as potential antipsychotics. 3. 6-Propyl-4,5,5a,6,7,8-hexahydrothiazolo[4,5-f]quinolin-2-amine

Dopamine autoreceptor agonists as potential antipsychotics. 3. 6-Propyl-4,5,5a,6,7,8-hexahydrothiazolo[4,5-f]quinolin-2-amine

by Caprathe, Bradley W, Jaen, Juan C, Wise, Lawrence D, Heffner, Thomas G, Pugsley, Thomas A, Meltzer, Leonard T, Parvez, Masood
Published in Journal of medicinal chemistry (01.09.1991)

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The design and synthesis of sulfonamides as caspase-1 inhibitors

The design and synthesis of sulfonamides as caspase-1 inhibitors

by Harter, William G., Albrect, Hans, Brady, Kenneth, Caprathe, Bradley, Dunbar, James, Gilmore, John, Hays, Sheryl, Kostlan, Catherine R., Lunney, Beth, Walker, Nigel
Published in Bioorganic & medicinal chemistry letters (09.02.2004)

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Z-(±)-1-azabicyclo[2.2.1]heptan-3-one, O-(3-aryl-2-propynyl) oximes as potential m1-subtype selective muscarinic agonists

Z-(±)-1-azabicyclo[2.2.1]heptan-3-one, O-(3-aryl-2-propynyl) oximes as potential m1-subtype selective muscarinic agonists

by Tecle, H., Jaen, J.C., Augelli-Szafran, C., Barrett, S.D., Caprathe, B.W., Lauffer, D.J., Mirzadegan, T., Moos, W.H., Moreland, D.W., Pavia, M.R., Schwarz, R.D., Thomas, A.J., Davis, R.E.
Published in Bioorganic & medicinal chemistry letters (16.03.1995)

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Design, Synthesis, and Biological Activity of Novel Polycyclic Aza-Amide FKBP12 Ligands

Design, Synthesis, and Biological Activity of Novel Polycyclic Aza-Amide FKBP12 Ligands

by Hudack, Raymond A, Barta, Nancy S, Guo, Chuangxing, Deal, Judith, Dong, Liming, Fay, Lorraine K, Caprathe, Bradley, Chatterjee, Arindam, Vanderpool, Darin, Bigge, Christopher, Showalter, Richard, Bender, Steve, Augelli-Szafran, Corinne E, Lunney, Elizabeth, Hou, Xinjun
Published in Journal of medicinal chemistry (09.02.2006)

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Assessment of mutagenic potential in a series of compounds structurally related to 2-amino-3-methylimidazo [4,5- f]quinoline (IQ)

Assessment of mutagenic potential in a series of compounds structurally related to 2-amino-3-methylimidazo [4,5- f]quinoline (IQ)

by Jaen, JC, Kropko, ML, Theiss, JC, Wold, S, Caprathe, BW, Wise, LD
Published in European journal of medicinal chemistry (1993)

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Nitrones by heterolytic fragmentation of .gamma.-N-hydroxyamino sulfonates. Conversion of a decahydroquinoline to a perhydroazaazulene

Nitrones by heterolytic fragmentation of .gamma.-N-hydroxyamino sulfonates. Conversion of a decahydroquinoline to a perhydroazaazulene

by LeBel, Norman A, Caprathe, Bradley W
Published in Journal of organic chemistry (01.10.1985)

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PD-90780, a Nonpeptide Inhibitor of Nerve Growth Factor′s Binding to the P75 NGF Receptor

PD-90780, a Nonpeptide Inhibitor of Nerve Growth Factor′s Binding to the P75 NGF Receptor

by Spiegel, K., Agrafiotis, D., Caprathe, B., Davis, R.E., Dickerson, M.R., Fergus, J.H., Hepburn, T.W., Marks, J.S., Vandorf, M., Wieland, D.M., Jaen, J.C.
Published in Biochemical and biophysical research communications (14.12.1995)

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CI-1007, a dopamine partial agonist and potential antipsychotic agent. I. Neurochemical effects

CI-1007, a dopamine partial agonist and potential antipsychotic agent. I. Neurochemical effects

by Rugsley, T A, Davis, M D, Akunne, H C, Cooke, L W, Whetzel, S Z, MacKenzie, R G, Shih, Y H, van Leeuwen, D H, DeMattos, S B, Georgic, L M
Published in The Journal of pharmacology and experimental therapeutics (01.08.1995)

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