DNA Topoisomerase II Structures and Anthracycline Activity: Insights into Ternary Complex Formation
Dal Ben, D, Palumbo, M, Zagotto, G, Capranico, G, Moro, S
Published in Current pharmaceutical design (01.09.2007)
Published in Current pharmaceutical design (01.09.2007)
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G1 cell-cycle arrest and apoptosis by histone deacetylase inhibition in MLL-AF9 acute myeloid leukemia cells is p21 dependent and MLL-AF9 independent
TONELLI, R, SARTINI, R, CAPRANICO, G, KHOBTA, A, CAMPANINI, R, PAOLUCCI, P, MINUCCI, S, PESSION, A, FRONZA, R, FRECCERO, F, FRANZONI, M, DONGIOVANNI, D, BALLARINI, M, FERRARI, S, D'APOLITO, M, DI COLA, G
Published in Leukemia (01.07.2006)
Published in Leukemia (01.07.2006)
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Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin
Jaxel, C, Capranico, G, Kerrigan, D, Kohn, K W, Pommier, Y
Published in The Journal of biological chemistry (25.10.1991)
Published in The Journal of biological chemistry (25.10.1991)
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Unique sequence specificity of topoisomerase II DNA cleavage stimulation and DNA binding mode of streptonigrin
Capranico, G, Palumbo, M, Tinelli, S, Zunino, F
Published in The Journal of biological chemistry (07.10.1994)
Published in The Journal of biological chemistry (07.10.1994)
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Influence of structural modifications at the 3' and 4' positions of doxorubicin on the drug ability to trap topoisomerase II and to overcome multidrug resistance
CAPRANICO, G, SUPINO, R, BINASCHI, M, CAPOLONGO, L, GRANDI, M, SUARATO, A, ZUNINO, F
Published in Molecular pharmacology (01.05.1994)
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Published in Molecular pharmacology (01.05.1994)
Journal Article
Effects of morpholinyl doxorubicins, doxorubicin, and actinomycin D on mammalian DNA topoisomerases I and II
WASSERMANN, K, MARKOVITS, J, JAXEL, C, CAPRANICO, G, KOHN, K. W, POMMIER, Y
Published in Molecular pharmacology (01.07.1990)
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Published in Molecular pharmacology (01.07.1990)
Journal Article
Topoisomerase II DNA cleavage stimulation, DNA binding activity, cytotoxicity, and physico-chemical properties of 2-aza- and 2-aza-oxide-anthracenedione derivatives
De Isabella, P, Palumbo, M, Sissi, C, Capranico, G, Carenini, N, Menta, E, Oliva, A, Spinelli, S, Krapcho, A P, Giuliani, F C
Published in Molecular pharmacology (01.07.1995)
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Published in Molecular pharmacology (01.07.1995)
Journal Article
Mapping DNA Breaks by Next-Generation Sequencing
Baranello, Laura, Kouzine, Fedor, Wojtowicz, Damian, Cui, Kairong, Zhao, Keji, Przytycka, Teresa M, Capranico, Giovanni, Levens, David
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2018)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2018)
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DNA topoisomerase II poisons and inhibitors
Capranico, G, Giaccone, G, D'Incalci, M
Published in Cancer chemotherapy and biological response modifiers (1999)
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Published in Cancer chemotherapy and biological response modifiers (1999)
Journal Article
Sequence selectivity of topoisomerase II DNA cleavage stimulated by mitoxantrone derivatives: relationships to drug DNA binding and cellular effects
DE ISABELLA, P, CAPRANICO, G, PALUMBO, M, SISSI, C, KRAPCHO, A. P, ZUNINO, F
Published in Molecular pharmacology (01.05.1993)
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Published in Molecular pharmacology (01.05.1993)
Journal Article
Biochemical and pharmacological activity of novel 8-fluoroanthracyclines: influence of stereochemistry and conformation
Animati, F, Arcamone, F, Bigioni, M, Capranico, G, Caserini, C, De Cesare, M, Lombardi, P, Pratesi, G, Salvatore, C, Supino, R, Zunino, F
Published in Molecular pharmacology (01.09.1996)
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Published in Molecular pharmacology (01.09.1996)
Journal Article
Anthracyclines: selected new developments
Binaschi, M, Bigioni, M, Cipollone, A, Rossi, C, Goso, C, Maggi, C A, Capranico, G, Animati, F
Published in Current medicinal chemistry. Anti-cancer agents (01.08.2001)
Published in Current medicinal chemistry. Anti-cancer agents (01.08.2001)
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Journal Article
Evidence of DNA topoisomerase II-dependent mechanisms of multidrug resistance in P388 leukemia cells
DE ISABELLA, P, CAPRANICO, G, BINASCHI, M, TINELLI, S, ZUNINO, F
Published in Molecular pharmacology (01.01.1990)
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Published in Molecular pharmacology (01.01.1990)
Journal Article
Conformational properties of topoisomerase II inhibitors and sequence specificity of DNA cleavage
Palumbo, M, Mabilia, M, Pozzan, A, Capranico, G, Tinelli, S, Zunino, F
Published in Journal of molecular recognition (01.09.1994)
Published in Journal of molecular recognition (01.09.1994)
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