Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist
Willard, Francis S, Douros, Jonathan D, Gabe, Maria Bn, Showalter, Aaron D, Wainscott, David B, Suter, Todd M, Capozzi, Megan E, van der Velden, Wijnand Jc, Stutsman, Cynthia, Cardona, Guemalli R, Urva, Shweta, Emmerson, Paul J, Holst, Jens J, D'Alessio, David A, Coghlan, Matthew P, Rosenkilde, Mette M, Campbell, Jonathan E, Sloop, Kyle W
Published in JCI insight (03.09.2020)
Published in JCI insight (03.09.2020)
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Journal Article
Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells
Gray, Sarah M., Xin, Yurong, Ross, Elizabeth C., Chazotte, Bryanna M., Capozzi, Megan E., El, Kimberley, Svendsen, Berit, Ravn, Peter, Sloop, Kyle W., Tong, Jenny, Gromada, Jesper, Campbell, Jonathan E., D'Alessio, David A.
Published in The Journal of biological chemistry (14.08.2020)
Published in The Journal of biological chemistry (14.08.2020)
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Journal Article
Cytochrome P450-epoxygenated fatty acids inhibit Müller glial inflammation
Ontko, Cayla D, Capozzi, Megan E, Kim, Minjae J, McCollum, Gary W, Penn, John S
Published in Scientific reports (06.05.2021)
Published in Scientific reports (06.05.2021)
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Journal Article
Pharmacological antagonism of the incretin system protects against diet-induced obesity
Svendsen, Berit, Capozzi, Megan E., Nui, Jingjing, Hannou, Sarah A., Finan, Brian, Naylor, Jacqueline, Ravn, Peter, D'Alessio, David A., Campbell, Jonathan E.
Published in Molecular metabolism (Germany) (01.02.2020)
Published in Molecular metabolism (Germany) (01.02.2020)
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Journal Article
Author Correction: Cytochrome P450-epoxygenated fatty acids inhibit Müller glial inflammation
Ontko, Cayla D., Capozzi, Megan E., Kim, Minjae J., McCollum, Gary W., Penn, John S.
Published in Scientific reports (16.09.2021)
Published in Scientific reports (16.09.2021)
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Journal Article
In Vivo Imaging of Retinal Hypoxia in a Model of Oxygen-Induced Retinopathy
Uddin, Md Imam, Evans, Stephanie M, Craft, Jason R, Capozzi, Megan E, McCollum, Gary W, Yang, Rong, Marnett, Lawrence J, Uddin, Md Jashim, Jayagopal, Ashwath, Penn, John S
Published in Scientific reports (05.08.2016)
Published in Scientific reports (05.08.2016)
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Journal Article
Repositioning Glucagon Action in the Physiology and Pharmacology of Diabetes
Finan, Brian, Capozzi, Megan E, Campbell, Jonathan E
Published in Diabetes (New York, N.Y.) (01.04.2020)
Published in Diabetes (New York, N.Y.) (01.04.2020)
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Journal Article
Pancreas-derived DPP4 is not essential for glucose homeostasis under metabolic stress
Fadzeyeva, Evgenia, Locatelli, Cassandra A.A., Trzaskalski, Natasha A., Nguyen, My-Anh, Capozzi, Megan E., Vulesevic, Branka, Morrow, Nadya M., Ghorbani, Peyman, Hanson, Antonio A., Lorenzen-Schmidt, Ilka, Doyle, Mary-Anne, Seymour, Richard, Varin, Elodie M., Fullerton, Morgan D., Campbell, Jonathan E., Mulvihill, Erin E.
Published in iScience (19.05.2023)
Published in iScience (19.05.2023)
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Journal Article
The past, present, and future physiology and pharmacology of glucagon
Capozzi, Megan E., D’Alessio, David A., Campbell, Jonathan E.
Published in Cell metabolism (01.11.2022)
Published in Cell metabolism (01.11.2022)
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Journal Article
Repositioning the Alpha Cell in Postprandial Metabolism
El, Kimberley, Capozzi, Megan E, Campbell, Jonathan E
Published in Endocrinology (Philadelphia) (01.11.2020)
Published in Endocrinology (Philadelphia) (01.11.2020)
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Journal Article
Targeting the Incretin/Glucagon System With Triagonists to Treat Diabetes
Capozzi, Megan E, DiMarchi, Richard D, Tschöp, Matthias H, Finan, Brian, Campbell, Jonathan E
Published in Endocrine reviews (01.10.2018)
Published in Endocrine reviews (01.10.2018)
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Journal Article
The Limited Role of Glucagon for Ketogenesis During Fasting or in Response to SGLT2 Inhibition
Capozzi, Megan E, Coch, Reilly W, Koech, Jepchumba, Astapova, Inna I, Wait, Jacob B, Encisco, Sara E, Douros, Jonathan D, El, Kimberly, Finan, Brian, Sloop, Kyle W, Herman, Mark A, D'Alessio, David A, Campbell, Jonathan E
Published in Diabetes (New York, N.Y.) (01.05.2020)
Published in Diabetes (New York, N.Y.) (01.05.2020)
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Journal Article
β Cell tone is defined by proglucagon peptides through cAMP signaling
Capozzi, Megan E, Svendsen, Berit, Encisco, Sara E, Lewandowski, Sophie L, Martin, Mackenzie D, Lin, Haopeng, Jaffe, Justin L, Coch, Reilly W, Haldeman, Jonathan M, MacDonald, Patrick E, Merrins, Matthew J, D'Alessio, David A, Campbell, Jonathan E
Published in JCI insight (07.03.2019)
Published in JCI insight (07.03.2019)
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Journal Article
Epoxygenated Fatty Acids Inhibit Retinal Vascular Inflammation
Capozzi, Megan E, Hammer, Sandra S, McCollum, Gary W, Penn, John S
Published in Scientific reports (14.12.2016)
Published in Scientific reports (14.12.2016)
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Journal Article
The ubiquitination status of the glucagon receptor determines signal bias
Kaur, Suneet, Sokrat, Badr, Capozzi, Megan E., El, Kimberley, Bai, Yushi, Jazic, Aeva, Han, Bridgette, Krishna Kumar, Kaavya, D'Alessio, David A., Campbell, Jonathan E., Bouvier, Michel, Shenoy, Sudha K.
Published in The Journal of biological chemistry (01.05.2023)
Published in The Journal of biological chemistry (01.05.2023)
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Journal Article
Nuclear factor of activated T-cells (NFAT) regulation of IL-1β-induced retinal vascular inflammation
Giblin, Meredith J., Smith, Taylor E., Winkler, Garrett, Pendergrass, Hannah A., Kim, Minjae J., Capozzi, Megan E., Yang, Rong, McCollum, Gary W., Penn, John S.
Published in Biochimica et biophysica acta. Molecular basis of disease (01.12.2021)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.12.2021)
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Journal Article