Single-step doxorubicin-selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes
Calcagno, A M, Fostel, J M, To, K K W, Salcido, C D, Martin, S E, Chewning, K J, Wu, C-P, Varticovski, L, Bates, S E, Caplen, N J, Ambudkar, S V
Published in British journal of cancer (06.05.2008)
Published in British journal of cancer (06.05.2008)
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From identification of therapeutic targets to clinical strategies
Kim, M.K.H, Hernandez, L, Caplen, N, Chakka, S, Annunziata, C.M
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Published in Gynecologic oncology (01.06.2016)
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RNAi screening identifies TAK1 as a potential target for the enhanced efficacy of topoisomerase inhibitors
Martin, S E, Wu, Z-H, Gehlhaus, K, Jones, T L, Zhang, Y-W, Guha, R, Miyamoto, S, Pommier, Y, Caplen, N J
Published in Current cancer drug targets (01.10.2011)
Published in Current cancer drug targets (01.10.2011)
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Specific Inhibition of Gene Expression by Small Double-Stranded RNAs in Invertebrate and Vertebrate Systems
Caplen, Natasha J., Parrish, Susan, Imani, Farhad, Fire, Andrew, Morgan, Richard A.
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2001)
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Short Interfering RNAs Can Induce Unexpected and Divergent Changes in the Levels of Untargeted Proteins in Mammalian Cells
Scacheri, Peter C., Rozenblatt-Rosen, Orit, Caplen, Natasha J., Wolfsberg, Tyra G., Umayam, Lowell, Lee, Jeffrey C., Hughes, Christina M., Shanmugam, Kalai Selvi, Bhattacharjee, Arindam, Meyerson, Matthew, Collins, Francis S., Vogelstein, Bert
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2004)
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RNAi microarray analysis in cultured mammalian cells
Mousses, Spyro, Caplen, Natasha J, Cornelison, Robert, Weaver, Don, Basik, Mark, Hautaniemi, Sampsa, Elkahloun, Abdel G, Lotufo, Roberto A, Choudary, Ashish, Dougherty, Edward R, Suh, Ed, Kallioniemi, Olli
Published in Genome research (01.10.2003)
Published in Genome research (01.10.2003)
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CFTR gene transfer reduces the binding of Pseudomonas aeruginosa to cystic fibrosis respiratory epithelium
Davies, JC, Stern, M, Dewar, A, Caplen, NJ, Munkonge, FM, Pitt, T, Sorgi, F, Huang, L, Bush, A, Geddes, DM, Alton, EW
Published in American journal of respiratory cell and molecular biology (01.06.1997)
Published in American journal of respiratory cell and molecular biology (01.06.1997)
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In vitro liposome-mediated DNA transfection of epithelial cell lines using the cationic liposome DC-Chol/DOPE
Caplen, N J, Kinrade, E, Sorgi, F, Gao, X, Gruenert, D, Geddes, D, Coutelle, C, Huang, L, Alton, E W, Williamson, R
Published in Gene therapy (01.11.1995)
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Published in Gene therapy (01.11.1995)
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Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
Caplen, N J, Alton, E W, Middleton, P G, Dorin, J R, Stevenson, B J, Gao, X, Durham, S R, Jeffery, P K, Hodson, M E, Coutelle, C
Published in Nature medicine (01.01.1995)
Published in Nature medicine (01.01.1995)
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Non-invasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice
Alton, E. W. F. W, Middleton, P. G, Caplen, N. J, Smith, S. N, Steel, D. M, Munkonge, F. M, Jeffery, P. K, Geddes, D. M, Hart, S. L, Williamson, R, Fasold, K. I, Miller, A. D, Dickinson, P, Stevenson, B. J, McLachlan, G, Dorin, J. R, Porteous, D. J
Published in Nature genetics (01.10.1993)
Published in Nature genetics (01.10.1993)
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The effects of jet nebulisation on cationic liposome-mediated gene transfer in vitro
STERN, M, SORGI, F, ALTON, E. W. F. W, HUGHES, C, CAPLEN, N. J, BROWNING, J. E, MIDDLETON, P. G, GRUENERT, D. C, FARR, S. J, HUANG, L, GEDDES, D. M
Published in Gene therapy (01.05.1998)
Published in Gene therapy (01.05.1998)
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