Inactivation of CDK12 Delineates a Distinct Immunogenic Class of Advanced Prostate Cancer
Wu, Yi-Mi, Cieślik, Marcin, Lonigro, Robert J., Vats, Pankaj, Reimers, Melissa A., Cao, Xuhong, Ning, Yu, Wang, Lisha, Kunju, Lakshmi P., de Sarkar, Navonil, Heath, Elisabeth I., Chou, Jonathan, Feng, Felix Y., Nelson, Peter S., de Bono, Johann S., Zou, Weiping, Montgomery, Bruce, Alva, Ajjai, Robinson, Dan R., Chinnaiyan, Arul M.
Published in Cell (14.06.2018)
Published in Cell (14.06.2018)
Get full text
Journal Article
Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination
Yu, Jiali, Green, Michael D, Li, Shasha, Sun, Yilun, Journey, Sara N, Choi, Jae Eun, Rizvi, Syed Monem, Qin, Angel, Waninger, Jessica J, Lang, Xueting, Chopra, Zoey, El Naqa, Issam, Zhou, Jiajia, Bian, Yingjie, Jiang, Long, Tezel, Alangoya, Skvarce, Jeremy, Achar, Rohan K, Sitto, Merna, Rosen, Benjamin S, Su, Fengyun, Narayanan, Sathiya P, Cao, Xuhong, Wei, Shuang, Szeliga, Wojciech, Vatan, Linda, Mayo, Charles, Morgan, Meredith A, Schonewolf, Caitlin A, Cuneo, Kyle, Kryczek, Ilona, Ma, Vincent T, Lao, Christopher D, Lawrence, Theodore S, Ramnath, Nithya, Wen, Fei, Chinnaiyan, Arul M, Cieslik, Marcin, Alva, Ajjai, Zou, Weiping
Published in Nature medicine (01.01.2021)
Published in Nature medicine (01.01.2021)
Get full text
Journal Article
The landscape of long noncoding RNAs in the human transcriptome
Iyer, Matthew K, Niknafs, Yashar S, Malik, Rohit, Singhal, Udit, Sahu, Anirban, Hosono, Yasuyuki, Barrette, Terrence R, Prensner, John R, Evans, Joseph R, Zhao, Shuang, Poliakov, Anton, Cao, Xuhong, Dhanasekaran, Saravana M, Wu, Yi-Mi, Robinson, Dan R, Beer, David G, Feng, Felix Y, Iyer, Hariharan K, Chinnaiyan, Arul M
Published in Nature genetics (01.03.2015)
Published in Nature genetics (01.03.2015)
Get full text
Journal Article
Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer
Asangani, Irfan A, Dommeti, Vijaya L, Wang, Xiaoju, Malik, Rohit, Cieslik, Marcin, Yang, Rendong, Escara-Wilke, June, Wilder-Romans, Kari, Dhanireddy, Sudheer, Engelke, Carl, Iyer, Mathew K, Jing, Xiaojun, Wu, Yi-Mi, Cao, Xuhong, Qin, Zhaohui S, Wang, Shaomeng, Feng, Felix Y, Chinnaiyan, Arul M
Published in Nature (London) (12.06.2014)
Published in Nature (London) (12.06.2014)
Get full text
Journal Article
Distinct structural classes of activating FOXA1 alterations in advanced prostate cancer
Parolia, Abhijit, Cieslik, Marcin, Chu, Shih-Chun, Xiao, Lanbo, Ouchi, Takahiro, Zhang, Yuping, Wang, Xiaoju, Vats, Pankaj, Cao, Xuhong, Pitchiaya, Sethuramasundaram, Su, Fengyun, Wang, Rui, Feng, Felix Y, Wu, Yi-Mi, Lonigro, Robert J, Robinson, Dan R, Chinnaiyan, Arul M
Published in Nature (London) (01.07.2019)
Published in Nature (London) (01.07.2019)
Get full text
Journal Article
Transcriptome sequencing to detect gene fusions in cancer
MAHER, Christopher A, KUMAR-SINHA, Chandan, XUHONG CAO, KALYANA-SUNDARAM, Shanker, BO HAN, XIAOJUN JING, SAM, Lee, BARRETTE, Terrence, PALANISAMY, Nallasivam, CHINNAIYAN, Arul M
Published in Nature (05.03.2009)
Published in Nature (05.03.2009)
Get full text
Journal Article
Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment
Kregel, Steven, Wang, Chao, Han, Xin, Xiao, Lanbo, Fernandez-Salas, Ester, Bawa, Pushpinder, McCollum, Brooke L., Wilder-Romans, Kari, Apel, Ingrid J., Cao, Xuhong, Speers, Corey, Wang, Shaomeng, Chinnaiyan, Arul M.
Published in Neoplasia (New York, N.Y.) (01.02.2020)
Published in Neoplasia (New York, N.Y.) (01.02.2020)
Get full text
Journal Article
Somatic Bi-allelic Loss of TSC Genes in Eosinophilic Solid and Cystic Renal Cell Carcinoma
Mehra, Rohit, Vats, Pankaj, Cao, Xuhong, Su, Fengyun, Lee, Nicole D., Lonigro, Robert, Premkumar, Kumpati, Trpkov, Kiril, McKenney, Jesse K., Dhanasekaran, Saravana M., Chinnaiyan, Arul M.
Published in European urology (01.10.2018)
Published in European urology (01.10.2018)
Get full text
Journal Article
Oncogenic Role of THOR, a Conserved Cancer/Testis Long Non-coding RNA
Hosono, Yasuyuki, Niknafs, Yashar S., Prensner, John R., Iyer, Matthew K., Dhanasekaran, Saravana M., Mehra, Rohit, Pitchiaya, Sethuramasundaram, Tien, Jean, Escara-Wilke, June, Poliakov, Anton, Chu, Shih-Chun, Saleh, Sahal, Sankar, Keerthana, Su, Fengyun, Guo, Shuling, Qiao, Yuanyuan, Freier, Susan M., Bui, Huynh-Hoa, Cao, Xuhong, Malik, Rohit, Johnson, Timothy M., Beer, David G., Feng, Felix Y., Zhou, Weibin, Chinnaiyan, Arul M.
Published in Cell (14.12.2017)
Published in Cell (14.12.2017)
Get full text
Journal Article
Activating ESR1 mutations in hormone-resistant metastatic breast cancer
Robinson, Dan R, Wu, Yi-Mi, Vats, Pankaj, Su, Fengyun, Lonigro, Robert J, Cao, Xuhong, Kalyana-Sundaram, Shanker, Wang, Rui, Ning, Yu, Hodges, Lynda, Gursky, Amy, Siddiqui, Javed, Tomlins, Scott A, Roychowdhury, Sameek, Pienta, Kenneth J, Kim, Scott Y, Roberts, J Scott, Rae, James M, Van Poznak, Catherine H, Hayes, Daniel F, Chugh, Rashmi, Kunju, Lakshmi P, Talpaz, Moshe, Schott, Anne F, Chinnaiyan, Arul M
Published in Nature genetics (01.12.2013)
Published in Nature genetics (01.12.2013)
Get full text
Journal Article
Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing
Robinson, Dan R, Wu, Yi-Mi, Kalyana-Sundaram, Shanker, Cao, Xuhong, Lonigro, Robert J, Sung, Yun-Shao, Chen, Chun-Liang, Zhang, Lei, Wang, Rui, Su, Fengyun, Iyer, Matthew K, Roychowdhury, Sameek, Siddiqui, Javed, Pienta, Kenneth J, Kunju, Lakshmi P, Talpaz, Moshe, Mosquera, Juan Miguel, Singer, Samuel, Schuetze, Scott M, Antonescu, Cristina R, Chinnaiyan, Arul M
Published in Nature genetics (01.02.2013)
Published in Nature genetics (01.02.2013)
Get full text
Journal Article
The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma
Harms, Paul William, Vats, Pankaj, Verhaegen, Monique Elise, Robinson, Dan R, Wu, Yi-Mi, Dhanasekaran, Saravana Mohan, Palanisamy, Nallasivam, Siddiqui, Javed, Cao, Xuhong, Su, Fengyun, Wang, Rui, Xiao, Hong, Kunju, Lakshmi P, Mehra, Rohit, Tomlins, Scott A, Fullen, Douglas Randall, Bichakjian, Christopher Keram, Johnson, Timothy M, Dlugosz, Andrzej Antoni, Chinnaiyan, Arul M
Published in Cancer research (Chicago, Ill.) (15.09.2015)
Published in Cancer research (Chicago, Ill.) (15.09.2015)
Get full text
Journal Article
An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer development
Shankar, Sunita, Tien, Jean Ching-Yi, Siebenaler, Ronald F, Chugh, Seema, Dommeti, Vijaya L, Zelenka-Wang, Sylvia, Wang, Xiao-Ming, Apel, Ingrid J, Waninger, Jessica, Eyunni, Sanjana, Xu, Alice, Mody, Malay, Goodrum, Andrew, Zhang, Yuping, Tesmer, John J, Mannan, Rahul, Cao, Xuhong, Vats, Pankaj, Pitchiaya, Sethuramasundaram, Ellison, Stephanie J, Shi, Jiaqi, Kumar-Sinha, Chandan, Crawford, Howard C, Chinnaiyan, Arul M
Published in Nature communications (04.06.2020)
Published in Nature communications (04.06.2020)
Get full text
Journal Article
Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1 , an unannotated lincRNA implicated in disease progression
Chinnaiyan, Arul M, Prensner, John R, Iyer, Matthew K, Balbin, O Alejandro, Dhanasekaran, Saravana M, Cao, Qi, Brenner, J Chad, Laxman, Bharathi, Asangani, Irfan A, Grasso, Catherine S, Kominsky, Hal D, Cao, Xuhong, Jing, Xiaojun, Wang, Xiaoju, Siddiqui, Javed, Wei, John T, Robinson, Daniel, Iyer, Hari K, Palanisamy, Nallasivam, Maher, Christopher A
Published in Nature biotechnology (01.08.2011)
Published in Nature biotechnology (01.08.2011)
Get full text
Journal Article
The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex
Prensner, John R, Iyer, Matthew K, Sahu, Anirban, Asangani, Irfan A, Cao, Qi, Patel, Lalit, Vergara, Ismael A, Davicioni, Elai, Erho, Nicholas, Ghadessi, Mercedeh, Jenkins, Robert B, Triche, Timothy J, Malik, Rohit, Bedenis, Rachel, McGregor, Natalie, Ma, Teng, Chen, Wei, Han, Sumin, Jing, Xiaojun, Cao, Xuhong, Wang, Xiaoju, Chandler, Benjamin, Yan, Wei, Siddiqui, Javed, Kunju, Lakshmi P, Dhanasekaran, Saravana M, Pienta, Kenneth J, Feng, Felix Y, Chinnaiyan, Arul M
Published in Nature genetics (01.11.2013)
Published in Nature genetics (01.11.2013)
Get full text
Journal Article
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression
Chinnaiyan, Arul M, Sreekumar, Arun, Poisson, Laila M, Rajendiran, Thekkelnaycke M, Khan, Amjad P, Cao, Qi, Yu, Jindan, Laxman, Bharathi, Mehra, Rohit, Lonigro, Robert J, Li, Yong, Nyati, Mukesh K, Ahsan, Aarif, Kalyana-Sundaram, Shanker, Han, Bo, Cao, Xuhong, Byun, Jaeman, Omenn, Gilbert S, Ghosh, Debashis, Pennathur, Subramaniam, Alexander, Danny C, Berger, Alvin, Shuster, Jeffrey R, Wei, John T, Varambally, Sooryanarayana, Beecher, Christopher
Published in Nature (London) (12.02.2009)
Published in Nature (London) (12.02.2009)
Get full text
Journal Article
Targeting Androgen Receptor and DNA Repair in Metastatic Castration-Resistant Prostate Cancer: Results From NCI 9012
Hussain, Maha, Daignault-Newton, Stephanie, Twardowski, Przemyslaw W, Albany, Costantine, Stein, Mark N, Kunju, Lakshmi P, Siddiqui, Javed, Wu, Yi-Mi, Robinson, Dan, Lonigro, Robert J, Cao, Xuhong, Tomlins, Scott A, Mehra, Rohit, Cooney, Kathleen A, Montgomery, Bruce, Antonarakis, Emmanuel S, Shevrin, Daniel H, Corn, Paul G, Whang, Young E, Smith, David C, Caram, Megan V, Knudsen, Karen E, Stadler, Walter M, Feng, Felix Y, Chinnaiyan, Arul M
Published in Journal of clinical oncology (01.04.2018)
Published in Journal of clinical oncology (01.04.2018)
Get full text
Journal Article
Overexpression of the Long Non-coding RNA SChLAP1 Independently Predicts Lethal Prostate Cancer
Mehra, Rohit, Udager, Aaron M, Ahearn, Thomas U, Cao, Xuhong, Feng, Felix Y, Loda, Massimo, Petimar, Joshua S, Kantoff, Philip, Mucci, Lorelei A, Chinnaiyan, Arul M
Published in European urology (01.10.2016)
Published in European urology (01.10.2016)
Get full text
Journal Article
Targeting the MYCN-PARP-DNA Damage Response Pathway in Neuroendocrine Prostate Cancer
Zhang, Wei, Liu, Bo, Wu, Wenhui, Li, Likun, Broom, Bradley M, Basourakos, Spyridon P, Korentzelos, Dimitrios, Luan, Yang, Wang, Jianxiang, Yang, Guang, Park, Sanghee, Azad, Abul Kalam, Cao, Xuhong, Kim, Jeri, Corn, Paul G, Logothetis, Christopher J, Aparicio, Ana M, Chinnaiyan, Arul M, Navone, Nora, Troncoso, Patricia, Thompson, Timothy C
Published in Clinical cancer research (01.02.2018)
Published in Clinical cancer research (01.02.2018)
Get full text
Journal Article
Next-generation RNA Sequencing–based Biomarker Characterization of Chromophobe Renal Cell Carcinoma and Related Oncocytic Neoplasms
Skala, Stephanie L., Wang, Xiaoming, Zhang, Yuping, Mannan, Rahul, Wang, Lisha, Narayanan, Sathiya P., Vats, Pankaj, Su, Fengyun, Chen, Jin, Cao, Xuhong, Siddiqui, Javed, Argani, Pedram, Cieślik, Marcin P., Giordano, Thomas J., Chinnaiyan, Arul M., Dhanasekaran, Saravana M., Mehra, Rohit
Published in European urology (01.07.2020)
Published in European urology (01.07.2020)
Get full text
Journal Article