Biallelic mutations in IRF8 impair human NK cell maturation and function
Mace, Emily M, Bigley, Venetia, Gunesch, Justin T, Chinn, Ivan K, Angelo, Laura S, Care, Matthew A, Maisuria, Sheetal, Keller, Michael D, Togi, Sumihito, Watkin, Levi B, LaRosa, David F, Jhangiani, Shalini N, Muzny, Donna M, Stray-Pedersen, Asbjørg, Coban Akdemir, Zeynep, Smith, Jansen B, Hernández-Sanabria, Mayra, Le, Duy T, Hogg, Graham D, Cao, Tram N, Freud, Aharon G, Szymanski, Eva P, Savic, Sinisa, Collin, Matthew, Cant, Andrew J, Gibbs, Richard A, Holland, Steven M, Caligiuri, Michael A, Ozato, Keiko, Paust, Silke, Doody, Gina M, Lupski, James R, Orange, Jordan S
Published in The Journal of clinical investigation (01.01.2017)
Published in The Journal of clinical investigation (01.01.2017)
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RivR Is a Negative Regulator of Virulence Factor Expression in Group A Streptococcus
Treviño, Jeanette, Liu, Zhuyun, Cao, Tram N, Ramirez-Peña, Esmeralda, Sumby, Paul
Published in Infection and Immunity (01.01.2013)
Published in Infection and Immunity (01.01.2013)
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High ambient glucose induces angiotensin-independent AT-1 receptor activation, leading to increases in proliferation and extracellular matrix accumulation in MES-13 mesangial cells
Yano, Naohiro, Suzuki, Daisuke, Endoh, Masayuki, Cao, Tram N, Dahdah, John R, Tseng, Andy, Stabila, Joan P, McGonnigal, Bethany G, Padbury, James F, Tseng, Yi-Tang
Published in Biochemical journal (01.10.2009)
Published in Biochemical journal (01.10.2009)
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Journal Article
Genetic and mechanistic diversity in pediatric hemophagocytic lymphohistiocytosis
Chinn, Ivan K., Eckstein, Olive S., Peckham-Gregory, Erin C., Goldberg, Baruch R., Forbes, Lisa R., Nicholas, Sarah K., Mace, Emily M., Vogel, Tiphanie P., Abhyankar, Harshal A., Diaz, Maria I., Heslop, Helen E., Krance, Robert A., Martinez, Caridad A., Nguyen, Trung C., Bashir, Dalia A., Goldman, Jordana R., Stray-Pedersen, Asbjørg, Pedroza, Luis A., Poli, M. Cecilia, Aldave-Becerra, Juan C., McGhee, Sean A., Al-Herz, Waleed, Chamdin, Aghiad, Coban-Akdemir, Zeynep H., Jhangiani, Shalini N., Muzny, Donna M., Cao, Tram N., Hong, Diana N., Gibbs, Richard A., Lupski, James R., Orange, Jordan S., McClain, Kenneth L., Allen, Carl E.
Published in Blood (05.07.2018)
Published in Blood (05.07.2018)
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Mutations in PI3K110δ cause impaired natural killer cell function partially rescued by rapamycin treatment
Ruiz-García, Raquel, Vargas-Hernández, Alexander, Chinn, Ivan K., Angelo, Laura S., Cao, Tram N., Coban-Akdemir, Zeynep, Jhangiani, Shalini N., Meng, Qingchang, Forbes, Lisa R., Muzny, Donna M., Allende, Luis M., Ehlayel, Mohammed S., Gibbs, Richard A., Lupski, James R., Uzel, Gulbu, Orange, Jordan S., Mace, Emily M.
Published in Journal of allergy and clinical immunology (01.08.2018)
Published in Journal of allergy and clinical immunology (01.08.2018)
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The small regulatory RNA FasX enhances group A Streptococcus virulence and inhibits pilus expression via serotype‐specific targets
Danger, Jessica L., Cao, Tram N., Cao, Tran H., Sarkar, Poulomee, Treviño, Jeanette, Pflughoeft, Kathryn J., Sumby, Paul
Published in Molecular microbiology (01.04.2015)
Published in Molecular microbiology (01.04.2015)
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Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure
Hamilton, Dale J, Zhang, Aijun, Li, Shumin, Cao, Tram N, Smith, Jessie A, Vedula, Indira, Cordero-Reyes, Andrea M, Youker, Keith A, Torre-Amione, Guillermo, Gupte, Anisha A
Published in American journal of physiology. Heart and circulatory physiology (15.03.2016)
Published in American journal of physiology. Heart and circulatory physiology (15.03.2016)
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Natural disruption of two regulatory networks in serotype M3 group A Streptococcus isolates contributes to the virulence factor profile of this hypervirulent serotype
Cao, Tram N, Liu, Zhuyun, Cao, Tran H, Pflughoeft, Kathryn J, Treviño, Jeanette, Danger, Jessica L, Beres, Stephen B, Musser, James M, Sumby, Paul
Published in Infection and immunity (01.05.2014)
Published in Infection and immunity (01.05.2014)
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Estrogen receptor alpha activation enhances mitochondrial function and systemic metabolism in high‐fat‐fed ovariectomized mice
Hamilton, Dale J., Minze, Laurie J., Kumar, Tanvi, Cao, Tram N., Lyon, Christopher J., Geiger, Paige C., Hsueh, Willa A., Gupte, Anisha A.
Published in Physiological reports (01.09.2016)
Published in Physiological reports (01.09.2016)
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Journal Article
Genetic and Mechanistic Diversity in Hemophagocytic Lymphohistiocytosis
Chinn, Ivan K., Eckstein, Olive S., Peckham-Gregory, Erin C., Goldberg, Baruch R., Forbes, Lisa R., Nicholas, Sarah K., Mace, Emily M., Vogel, Tiphanie P., Abhyankar, Harshal A., Diaz, Maria I., Heslop, Helen E., Krance, Robert A., Martinez, Caridad A., Nguyen, Trung C., Bashir, Dalia A., Goldman, Jordana R., Stray-Pedersen, Asbjorg, Pedroza, Luis A., Poli, M. Cecilia, Aldave Becerra, Juan Carlos, McGhee, Sean A., Coban-Akdemir, Zeynep H., Jhangiani, Shalini N., Muzny, Donna M., Cao, Tram N., Hong, Diana N., Gibbs, Richard A., Lupski, James R., Orange, Jordan S., McClain, Kenneth L., Allen, Carl E.
Published in Journal of allergy and clinical immunology (01.02.2018)
Published in Journal of allergy and clinical immunology (01.02.2018)
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A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function
Lam, Michael T, Coppola, Simona, Krumbach, Oliver H F, Prencipe, Giusi, Insalaco, Antonella, Cifaldi, Cristina, Brigida, Immacolata, Zara, Erika, Scala, Serena, Di Cesare, Silvia, Martinelli, Simone, Di Rocco, Martina, Pascarella, Antonia, Niceta, Marcello, Pantaleoni, Francesca, Ciolfi, Andrea, Netter, Petra, Carisey, Alexandre F, Diehl, Michael, Akbarzadeh, Mohammad, Conti, Francesca, Merli, Pietro, Pastore, Anna, Levi Mortera, Stefano, Camerini, Serena, Farina, Luciapia, Buchholzer, Marcel, Pannone, Luca, Cao, Tram N, Coban-Akdemir, Zeynep H, Jhangiani, Shalini N, Muzny, Donna M, Gibbs, Richard A, Basso-Ricci, Luca, Chiriaco, Maria, Dvorsky, Radovan, Putignani, Lorenza, Carsetti, Rita, Janning, Petra, Stray-Pedersen, Asbjorg, Erichsen, Hans Christian, Horne, AnnaCarin, Bryceson, Yenan T, Torralba-Raga, Lamberto, Ramme, Kim, Rosti, Vittorio, Bracaglia, Claudia, Messia, Virginia, Palma, Paolo, Finocchi, Andrea, Locatelli, Franco, Chinn, Ivan K, Lupski, James R, Mace, Emily M, Cancrini, Caterina, Aiuti, Alessandro, Ahmadian, Mohammad R, Orange, Jordan S, De Benedetti, Fabrizio, Tartaglia, Marco
Published in The Journal of experimental medicine (02.12.2019)
Published in The Journal of experimental medicine (02.12.2019)
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Primary immunodeficiency diseases: Genomic approaches delineate heterogeneous Mendelian disorders
Stray-Pedersen, Asbjørg, MD, PhD, Sorte, Hanne Sørmo, MS, Samarakoon, Pubudu, MS, Gambin, Tomasz, PhD, Chinn, Ivan K., MD, Coban Akdemir, Zeynep H., PhD, Erichsen, Hans Christian, MD, PhD, Forbes, Lisa R., MD, Gu, Shen, PhD, Yuan, Bo, PhD, Jhangiani, Shalini N., MS, Muzny, Donna M., MS, Rødningen, Olaug Kristin, PhD, Sheng, Ying, PhD, Nicholas, Sarah K., MD, PhD, Noroski, Lenora M., MD, MPH, Seeborg, Filiz O., MD, MPH, Davis, Carla M., MD, Canter, Debra L., MS, Mace, Emily M., PhD, Vece, Timothy J., MD, Allen, Carl E., MD, PhD, Abhyankar, Harshal A., MS, Boone, Philip M., MD, PhD, Beck, Christine R., PhD, Wiszniewski, Wojciech, MD, PhD, Fevang, Børre, MD, PhD, Aukrust, Pål, MD, PhD, Tjønnfjord, Geir E., MD, PhD, Gedde-Dahl, Tobias, MD, PhD, Hjorth-Hansen, Henrik, MD, PhD, Dybedal, Ingunn, MD, PhD, Nordøy, Ingvild, MD, PhD, Jørgensen, Silje F., MD, Abrahamsen, Tore G., MD, PhD, Øverland, Torstein, MD, Bechensteen, Anne Grete, MD, PhD, Skogen, Vegard, MD, PhD, Osnes, Liv T.N., MD, PhD, Kulseth, Mari Ann, PhD, Prescott, Trine E., MD, Rustad, Cecilie F., MD, Heimdal, Ketil R., MD, PhD, Belmont, John W., MD, PhD, Rider, Nicholas L., DO, Chinen, Javier, MD, PhD, Cao, Tram N., MS, Smith, Eric A., BSc, Caldirola, Maria Soledad, BSc, Bezrodnik, Liliana, MD, Lugo Reyes, Saul Oswaldo, MD, Espinosa Rosales, Francisco J., MD, Guerrero-Cursaru, Nina Denisse, BSc, Pedroza, Luis Alberto, PhD, Poli, Cecilia M., MD, Franco, Jose L., MD, PhD, Trujillo Vargas, Claudia M., PhD, Aldave Becerra, Juan Carlos, MD, Wright, Nicola, MD, Issekutz, Thomas B., MD, Issekutz, Andrew C., MD, Abbott, Jordan, MD, Caldwell, Jason W., DO, Bayer, Diana K., DO, Chan, Alice Y., MD, PhD, Aiuti, Alessandro, MD, PhD, Cancrini, Caterina, MD, PhD, Holmberg, Eva, MD, West, Christina, MD, PhD, Burstedt, Magnus, MD, PhD, Karaca, Ender, MD, Yesil, Gözde, MD, Artac, Hasibe, MD, Bayram, Yavuz, MD, Atik, Mehmed Musa, BSc, Eldomery, Mohammad K., MD, Ehlayel, Mohammad S., MD, PhD, Jolles, Stephen, MD, PhD, Flatø, Berit, MD, PhD, Bertuch, Alison A., MD, PhD, Hanson, I. Celine, MD, Zhang, Victor W., PhD, Wong, Lee-Jun, PhD, Hu, Jianhong, PhD, Walkiewicz, Magdalena, PhD, Yang, Yaping, PhD, Eng, Christine M., MD, Boerwinkle, Eric, PhD, Gibbs, Richard A., PhD, Shearer, William T., MD, PhD, Lyle, Robert, PhD, Orange, Jordan S., MD, PhD, Lupski, James R., MD, PhD, DSc (Hon)
Published in Journal of allergy and clinical immunology (01.01.2017)
Published in Journal of allergy and clinical immunology (01.01.2017)
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HEM1 deficiency disrupts mTORC2 and F-actin control in inherited immunodysregulatory disease
Cook, Sarah A, Comrie, William A, Poli, M Cecilia, Similuk, Morgan, Oler, Andrew J, Faruqi, Aiman J, Kuhns, Douglas B, Yang, Sheng, Vargas-Hernández, Alexander, Carisey, Alexandre F, Fournier, Benjamin, Anderson, D Eric, Price, Susan, Smelkinson, Margery, Abou Chahla, Wadih, Forbes, Lisa R, Mace, Emily M, Cao, Tram N, Coban-Akdemir, Zeynep H, Jhangiani, Shalini N, Muzny, Donna M, Gibbs, Richard A, Lupski, James R, Orange, Jordan S, Cuvelier, Geoffrey D E, Al Hassani, Moza, Al Kaabi, Nawal, Al Yafei, Zain, Jyonouchi, Soma, Raje, Nikita, Caldwell, Jason W, Huang, Yanping, Burkhardt, Janis K, Latour, Sylvain, Chen, Baoyu, ElGhazali, Gehad, Rao, V Koneti, Chinn, Ivan K, Lenardo, Michael J
Published in Science (American Association for the Advancement of Science) (10.07.2020)
Published in Science (American Association for the Advancement of Science) (10.07.2020)
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The small regulatory RNA FasX enhances group A S treptococcus virulence and inhibits pilus expression via serotype‐specific targets
Danger, Jessica L., Cao, Tram N., Cao, Tran H., Sarkar, Poulomee, Treviño, Jeanette, Pflughoeft, Kathryn J., Sumby, Paul
Published in Molecular microbiology (01.04.2015)
Published in Molecular microbiology (01.04.2015)
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Journal Article
Combination of angiotensin II and l - N G -nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure
Hamilton, Dale J., Zhang, Aijun, Li, Shumin, Cao, Tram N., Smith, Jessie A., Vedula, Indira, Cordero-Reyes, Andrea M., Youker, Keith A., Torre-Amione, Guillermo, Gupte, Anisha A.
Published in American journal of physiology. Heart and circulatory physiology (15.03.2016)
Published in American journal of physiology. Heart and circulatory physiology (15.03.2016)
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Journal Article
Combination of angiotensin II and L-N^sup G^-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure
Hamilton, Dale J, Zhang, Aijun, Li, Shumin, Cao, Tram N, Smith, Jessie A, Vedula, Indira, Cordero-Reyes, Andrea M, Youker, Keith A, Torre-Amione, Guillermo, Gupte, Anisha A
Published in American journal of physiology. Heart and circulatory physiology (15.03.2016)
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Published in American journal of physiology. Heart and circulatory physiology (15.03.2016)
Journal Article
Combination of angiotensin II and L-N super( G)-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure
Hamilton, Dale J, Zhang, Aijun, Li, Shumin, Cao, Tram N, Smith, Jessie A, Vedula, Indira, Cordero-Reyes, Andrea M, Youker, Keith A, Torre-Amione, Guillermo, Gupte, Anisha A
Published in American journal of physiology. Heart and circulatory physiology (01.03.2016)
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Published in American journal of physiology. Heart and circulatory physiology (01.03.2016)
Journal Article
Mutations in PI3K110δ cause impaired NK cell function partially rescued by rapamycin treatment
Ruiz-García, Raquel, Vargas-Hernandez, Alexander, Chinn, Ivan K., Angelo, Laura S., Cao, Tram N., Coban-Akdemir, Zeynep, Jhangiani, Shalini N., Meng, Qingchang, Forbes, Lisa R., Muzny, Donna M., Allende, Luis M., Ehlayel, Mohammed S., Gibbs, Richard A., Lupski, James R., Uzel, Gulbu, Orange, Jordan S., Mace, Emily M.
Published in Journal of allergy and clinical immunology (10.01.2018)
Published in Journal of allergy and clinical immunology (10.01.2018)
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