Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers
Cantley, Jennifer, Ye, Xiaofen, Rousseau, Emma, Januario, Tom, Hamman, Brian D., Rose, Christopher M., Cheung, Tommy K., Hinkle, Trent, Soto, Leofal, Quinn, Connor, Harbin, Alicia, Bortolon, Elizabeth, Chen, Xin, Haskell, Roy, Lin, Eva, Yu, Shang-Fan, Del Rosario, Geoff, Chan, Emily, Dunlap, Debra, Koeppen, Hartmut, Martin, Scott, Merchant, Mark, Grimmer, Matt, Broccatelli, Fabio, Wang, Jing, Pizzano, Jennifer, Dragovich, Peter S., Berlin, Michael, Yauch, Robert L.
Published in Nature communications (10.11.2022)
Published in Nature communications (10.11.2022)
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Journal Article
CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance
Cantley, Jennifer L., Yoshimura, Toru, Camporez, Joao Paulo G., Zhang, Dongyan, Jornayvaz, Francois R., Kumashiro, Naoki, Guebre-Egziabher, Fitsum, Jurczak, Michael J., Kahn, Mario, Guigni, Bias A., Serr, Julie, Hankin, Joseph, Murphy, Robert C., Cline, Gary W., Bhanot, Sanjay, Manchem, Vara Prasad, Brown, J. Mark, Samuel, Varman T., Shulman, Gerald I.
Published in Proceedings of the National Academy of Sciences - PNAS (29.01.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (29.01.2013)
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Journal Article
Targeting Pyruvate Carboxylase Reduces Gluconeogenesis and Adiposity and Improves Insulin Resistance
KUMASHIRO, Naoki, BEDDOW, Sara A, KAHN, Mario, PERLER, Bryce K, PUCHOWICZ, Michelle A, VARA PRASAD MANCHEM, BHANOT, Sanjay, STILL, Christopher D, GERHARD, Glenn S, PETERSEN, Kitt Falk, CLINE, Gary W, SHULMAN, Gerald I, VATNER, Daniel F, SAMUEL, Varman T, MAJUMDAR, Sachin K, CANTLEY, Jennifer L, GUEBRE-EGZIABHER, Fitsum, FAT, Ioana, GUIGNI, Blas, JURCZAK, Michael J, BIRKENFELD, Andreas L
Published in Diabetes (New York, N.Y.) (01.07.2013)
Published in Diabetes (New York, N.Y.) (01.07.2013)
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Journal Article
Role of patatin‐like phospholipase domain‐containing 3 on lipid‐induced hepatic steatosis and insulin resistance in rats
Kumashiro, Naoki, Yoshimura, Toru, Cantley, Jennifer L., Majumdar, Sachin K., Guebre‐Egziabher, Fitsum, Kursawe, Romy, Vatner, Daniel F., Fat, Ioana, Kahn, Mario, Erion, Derek M., Zhang, Xian‐Man, Zhang, Dongyan, Manchem, Vara Prasad, Bhanot, Sanjay, Gerhard, Glenn S., Petersen, Kitt F., Cline, Gary W., Samuel, Varman T., Shulman, Gerald I.
Published in Hepatology (Baltimore, Md.) (01.05.2013)
Published in Hepatology (Baltimore, Md.) (01.05.2013)
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Journal Article
Development of Liposome Systems for Enhancing the PK Properties of Bivalent PROTACs
Kou, Ponien, Levy, Elizabeth S, Nguyen, An D, Zhang, Donglu, Chen, Shu, Cui, Yusi, Zhang, Xing, Broccatelli, Fabio, Pizzano, Jennifer, Cantley, Jennifer, Bortolon, Elizabeth, Rousseau, Emma, Berlin, Michael, Dragovich, Peter, Sethuraman, Vijay
Published in Pharmaceutics (01.08.2023)
Published in Pharmaceutics (01.08.2023)
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Journal Article
Development of a Targeted Urine Proteome Assay for kidney diseases
Cantley, Lloyd G., Colangelo, Christopher M., Stone, Kathryn L., Chung, Lisa, Belcher, Justin, Abbott, Thomas, Cantley, Jennifer L., Williams, Kenneth R., Parikh, Chirag R.
Published in Proteomics. Clinical applications (01.01.2016)
Published in Proteomics. Clinical applications (01.01.2016)
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Journal Article
Targeting steroid receptor coactivator 1 with antisense oligonucleotides increases insulin-stimulated skeletal muscle glucose uptake in chow-fed and high-fat-fed male rats
Cantley, Jennifer L, Vatner, Daniel F, Galbo, Thomas, Madiraju, Anila, Petersen, Max, Perry, Rachel J, Kumashiro, Naoki, Guebre-Egziabher, Fitsum, Gattu, Arijeet K, Stacy, Mitchel R, Dione, Donald P, Sinusas, Albert J, Ragolia, Louis, Hall, Christopher E, Manchem, Vara Prasad, Bhanot, Sanjay, Bogan, Jonathan S, Samuel, Varman T
Published in American journal of physiology: endocrinology and metabolism (01.11.2014)
Published in American journal of physiology: endocrinology and metabolism (01.11.2014)
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Journal Article
PROTACs Targeting BRM (SMARCA2) Afford Selective In Vivo Degradation over BRG1 (SMARCA4) and Are Active in BRG1 Mutant Xenograft Tumor Models
Berlin, Michael, Cantley, Jennifer, Bookbinder, Mark, Bortolon, Elizabeth, Broccatelli, Fabio, Cadelina, Greg, Chan, Emily W., Chen, Huifen, Chen, Xin, Cheng, Yunxing, Cheung, Tommy K., Davenport, Kim, DiNicola, Dean, Gordon, Debbie, Hamman, Brian D., Harbin, Alicia, Haskell, Roy, He, Mingtao, Hole, Alison J., Januario, Thomas, Kerry, Philip S., Koenig, Stefan G., Li, Limei, Merchant, Mark, Pérez-Dorado, Inmaculada, Pizzano, Jennifer, Quinn, Connor, Rose, Christopher M., Rousseau, Emma, Soto, Leofal, Staben, Leanna R., Sun, Hongming, Tian, Qingping, Wang, Jing, Wang, Weifeng, Ye, Crystal S., Ye, Xiaofen, Zhang, Penghong, Zhou, Yuhui, Yauch, Robert, Dragovich, Peter S.
Published in Journal of medicinal chemistry (25.01.2024)
Published in Journal of medicinal chemistry (25.01.2024)
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Journal Article
Abstract 5687: Selective, chemically-induced degradation of BRM ( SMARCA2 ) enables in vivo efficacy in BRG1 ( SMARCA4 )-deficient xenograft tumor models
Berlin, Michael, Cantley, Jennifer, Wang, Jing, Bookbinder, Mark, Cadelina, Gregory, Chan, Emily, Chen, Huifen, Chen, Xin, Davenport, Kim, Fernando, Tharu, Gordon, Debbie, Hamman, Brian, Haskell, Roy, Ishchenko, Alexey, Kirkpatrick, Donald S., Maher, Jonathan, Merchant, Mark, Moffat, John, Morgan, Alicia, Nguyen, An, Pizzano, Jennifer, Quinn, Connor, Rose, Christopher M., Rousseau, Emma, Sethuraman, Vijay, Staben, Leanna, Wilson, Catherine, Ye, Xiaofen, Broccatelli, Fabio, Yauch, Robert, Dragovich, Peter S.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Quantification of Urinary Protein Biomarkers of Autosomal Dominant Polycystic Kidney Disease by Parallel Reaction Monitoring
Rauniyar, Navin, Yu, Xiaoqing, Cantley, Jennifer, Voss, Edward Z., Belcher, Justin, Colangelo, Christopher M., Stone, Kathryn L., Dahl, Neera, Parikh, Chirag, Lam, TuKiet T., Cantley, Lloyd G.
Published in Proteomics. Clinical applications (01.09.2018)
Published in Proteomics. Clinical applications (01.09.2018)
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Journal Article
COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF IRAK-4
MEDINA, Jesus Raul, CANTLEY, Jennifer L, HORNBERGER, Keith R, ARAUJO, Erika Marina Vieira
Year of Publication 30.03.2023
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Year of Publication 30.03.2023
Patent
COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF IRAK-4
MEDINA, Jesus Raul, CANTLEY, Jennifer L, HORNBERGER, Keith R, ARAUJO, Erika Marina Vieira
Year of Publication 22.12.2022
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Year of Publication 22.12.2022
Patent