Oleanolic Acid Derivatives as Potential Inhibitors of HIV‑1 Protease
Medina-O’Donnell, Marta, Rivas, Francisco, Reyes-Zurita, Fernando J, Cano-Muñoz, Mario, Martinez, Antonio, Lupiañez, Jose A, Parra, Andres
Published in Journal of natural products (Washington, D.C.) (25.10.2019)
Published in Journal of natural products (Washington, D.C.) (25.10.2019)
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Journal Article
Phosphorylation of cytosolic hPGK1 affects protein stability and ligand binding: implications for its subcellular targeting in cancer
Pacheco‐García, Juan Luis, Cano‐Muñoz, Mario, Loginov, Dmitry S., Vankova, Pavla, Man, Petr, Pey, Angel L.
Published in The FEBS journal (06.09.2024)
Published in The FEBS journal (06.09.2024)
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Journal Article
Extremely Thermostabilizing Core Mutations in Coiled-Coil Mimetic Proteins of HIV-1 gp41 Produce Diverse Effects on Target Binding but Do Not Affect Their Inhibitory Activity
Cano-Muñoz, Mario, Cesaro, Samuele, Morel, Bertrand, Lucas, Julie, Moog, Christiane, Conejero-Lara, Francisco
Published in Biomolecules (Basel, Switzerland) (12.04.2021)
Published in Biomolecules (Basel, Switzerland) (12.04.2021)
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Journal Article
Conformational flexibility of the conserved hydrophobic pocket of HIV-1 gp41. Implications for the discovery of small-molecule fusion inhibitors
Cano-Muñoz, Mario, Jurado, Samuel, Morel, Bertrand, Conejero-Lara, Francisco
Published in International journal of biological macromolecules (01.12.2021)
Published in International journal of biological macromolecules (01.12.2021)
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Journal Article
Thermodynamic dissection of the interface between HIV-1 gp41 heptad repeats reveals cooperative interactions and allosteric effects
Jurado, Samuel, Cano-Muñoz, Mario, Polo-Megías, Daniel, Conejero-Lara, Francisco, Morel, Bertrand
Published in Archives of biochemistry and biophysics (30.07.2020)
Published in Archives of biochemistry and biophysics (30.07.2020)
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Journal Article
Investigating vulnerability of the conserved SARS-CoV-2 spike's heptad repeat 2 as target for fusion inhibitors using chimeric miniproteins
Polo-Megías, Daniel, Cano-Muñoz, Mario, Berruezo, Alberto G., Laumond, Géraldine, Moog, Christiane, Conejero-Lara, Francisco
Published in International journal of biological macromolecules (01.03.2024)
Published in International journal of biological macromolecules (01.03.2024)
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Journal Article
Conformational Stabilization of Gp41-Mimetic Miniproteins Opens Up New Ways of Inhibiting HIV-1 Fusion
Cano-Muñoz, Mario, Lucas, Julie, Lin, Li-Yun, Cesaro, Samuele, Moog, Christiane, Conejero-Lara, Francisco
Published in International journal of molecular sciences (03.03.2022)
Published in International journal of molecular sciences (03.03.2022)
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Journal Article
Loss of stability and unfolding cooperativity in hPGK1 upon gradual structural perturbation of its N-terminal domain hydrophobic core
Pacheco-García, Juan Luis, Loginov, Dmitry S, Naganathan, Athi N, Vankova, Pavla, Cano-Muñoz, Mario, Man, Petr, Pey, Angel L
Published in Scientific reports (13.10.2022)
Published in Scientific reports (13.10.2022)
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Journal Article
Exploring Highly Conserved Regions of SARS-CoV-2 Spike S2 Subunit as Targets for Fusion Inhibition Using Chimeric Proteins
Polo-Megías, Daniel, Cano-Muñoz, Mario, Berruezo, Alberto G, Laumond, Géraldine, Moog, Christiane, Conejero-Lara, Francisco
Published in International journal of molecular sciences (07.12.2022)
Published in International journal of molecular sciences (07.12.2022)
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Journal Article
Naturally-Occurring Rare Mutations Cause Mild to Catastrophic Effects in the Multifunctional and Cancer-Associated NQO1 Protein
Pacheco-García, Juan Luis, Cano-Muñoz, Mario, Sánchez-Ramos, Isabel, Salido, Eduardo, Pey, Angel L
Published in Journal of personalized medicine (03.11.2020)
Published in Journal of personalized medicine (03.11.2020)
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Journal Article
Probing Vulnerability of the gp41 C-Terminal Heptad Repeat as Target for Miniprotein HIV Inhibitors
Jurado, Samuel, Moog, Christiane, Cano-Muñoz, Mario, Schmidt, Sylvie, Laumond, Géraldine, Ruocco, Valentina, Standoli, Sara, Polo-Megías, Daniel, Conejero-Lara, Francisco, Morel, Bertrand
Published in Journal of molecular biology (18.09.2020)
Published in Journal of molecular biology (18.09.2020)
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Journal Article
Structural and Thermodynamic Analysis of HIV-1 Fusion Inhibition Using Small gp41 Mimetic Proteins
Jurado, Samuel, Cano-Muñoz, Mario, Morel, Bertrand, Standoli, Sara, Santarossa, Elisabetta, Moog, Christiane, Schmidt, Sylvie, Laumond, Géraline, Cámara-Artigas, Ana, Conejero-Lara, Francisco
Published in Journal of molecular biology (09.08.2019)
Published in Journal of molecular biology (09.08.2019)
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Journal Article
Novel chimeric proteins mimicking SARS-CoV-2 spike epitopes with broad inhibitory activity
Cano-Muñoz, Mario, Polo-Megías, Daniel, Cámara-Artigas, Ana, Gavira, José A., López-Rodríguez, María J., Laumond, Géraldine, Schmidt, Sylvie, Demiselle, Julien, Bahram, Seiamak, Moog, Christiane, Conejero-Lara, Francisco
Published in International journal of biological macromolecules (01.12.2022)
Published in International journal of biological macromolecules (01.12.2022)
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Journal Article