Patients with Cancer Appear More Vulnerable to SARS-CoV-2: A Multicenter Study during the COVID-19 Outbreak
Dai, Mengyuan, Liu, Dianbo, Liu, Miao, Zhou, Fuxiang, Li, Guiling, Chen, Zhen, Zhang, Zhian, You, Hua, Wu, Meng, Zheng, Qichao, Xiong, Yong, Xiong, Huihua, Wang, Chun, Chen, Changchun, Xiong, Fei, Zhang, Yan, Peng, Yaqin, Ge, Siping, Zhen, Bo, Yu, Tingting, Wang, Ling, Wang, Hua, Liu, Yu, Chen, Yeshan, Mei, Junhua, Gao, Xiaojia, Li, Zhuyan, Gan, Lijuan, He, Can, Li, Zhen, Shi, Yuying, Qi, Yuwen, Yang, Jing, Tenen, Daniel G, Chai, Li, Mucci, Lorelei A, Santillana, Mauricio, Cai, Hongbing
Published in Cancer discovery (01.06.2020)
Published in Cancer discovery (01.06.2020)
Get full text
Journal Article
Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts
Elyada, Ela, Bolisetty, Mohan, Laise, Pasquale, Flynn, William F, Courtois, Elise T, Burkhart, Richard A, Teinor, Jonathan A, Belleau, Pascal, Biffi, Giulia, Lucito, Matthew S, Sivajothi, Santhosh, Armstrong, Todd D, Engle, Dannielle D, Yu, Kenneth H, Hao, Yuan, Wolfgang, Christopher L, Park, Youngkyu, Preall, Jonathan, Jaffee, Elizabeth M, Califano, Andrea, Robson, Paul, Tuveson, David A
Published in Cancer discovery (01.08.2019)
Published in Cancer discovery (01.08.2019)
Get full text
Journal Article
Spatiotemporal Immune Landscape of Colorectal Cancer Liver Metastasis at Single-Cell Level
Wu, Yingcheng, Yang, Shuaixi, Ma, Jiaqiang, Chen, Zechuan, Song, Guohe, Rao, Dongning, Cheng, Yifei, Huang, Siyuan, Liu, Yifei, Jiang, Shan, Liu, Jinxia, Huang, Xiaowu, Wang, Xiaoying, Qiu, Shuangjian, Xu, Jianmin, Xi, Ruibin, Bai, Fan, Zhou, Jian, Fan, Jia, Zhang, Xiaoming, Gao, Qiang
Published in Cancer discovery (01.01.2022)
Published in Cancer discovery (01.01.2022)
Get full text
Journal Article
Case Fatality Rate of Cancer Patients with COVID-19 in a New York Hospital System
Mehta, Vikas, Goel, Sanjay, Kabarriti, Rafi, Cole, Daniel, Goldfinger, Mendel, Acuna-Villaorduna, Ana, Pradhan, Kith, Thota, Raja, Reissman, Stan, Sparano, Joseph A, Gartrell, Benjamin A, Smith, Richard V, Ohri, Nitin, Garg, Madhur, Racine, Andrew D, Kalnicki, Shalom, Perez-Soler, Roman, Halmos, Balazs, Verma, Amit
Published in Cancer discovery (01.07.2020)
Published in Cancer discovery (01.07.2020)
Get full text
Journal Article
Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11
Lang, Xueting, Green, Michael D, Wang, Weimin, Yu, Jiali, Choi, Jae Eun, Jiang, Long, Liao, Peng, Zhou, Jiajia, Zhang, Qiang, Dow, Ania, Saripalli, Anjali L, Kryczek, Ilona, Wei, Shuang, Szeliga, Wojciech, Vatan, Linda, Stone, Everett M, Georgiou, George, Cieslik, Marcin, Wahl, Daniel R, Morgan, Meredith A, Chinnaiyan, Arul M, Lawrence, Theodore S, Zou, Weiping
Published in Cancer discovery (01.12.2019)
Published in Cancer discovery (01.12.2019)
Get full text
Journal Article
The Next Decade of Immune Checkpoint Therapy
Sharma, Padmanee, Siddiqui, Bilal A, Anandhan, Swetha, Yadav, Shalini S, Subudhi, Sumit K, Gao, Jianjun, Goswami, Sangeeta, Allison, James P
Published in Cancer discovery (01.04.2021)
Published in Cancer discovery (01.04.2021)
Get full text
Journal Article
Tumor Mutational Burden as a Predictive Biomarker in Solid Tumors
Sha, Dan, Jin, Zhaohui, Budczies, Jan, Kluck, Klaus, Stenzinger, Albrecht, Sinicrope, Frank A
Published in Cancer discovery (01.12.2020)
Published in Cancer discovery (01.12.2020)
Get full text
Journal Article
Single-cell analysis reveals fibroblast clusters linked to immunotherapy resistance in cancer
Kieffer, Yann, Hocine, Hocine R, Gentric, Geraldine, Pelon, Floriane, Bernard, Charles, Bourachot, Brigitte, Lameiras, Sonia, Albergante, Luca, Bonneau, Claire, Guyard, Alice, Tarte, Karin, Zinovyev, Andrei, Baulande, Sylvain, Zalcman, Gerard, Vincent-Salomon, Anne, Mechta-Grigoriou, Fatima
Published in Cancer discovery (01.09.2020)
Published in Cancer discovery (01.09.2020)
Get full text
Journal Article
STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS -Mutant Lung Adenocarcinoma
Skoulidis, Ferdinandos, Goldberg, Michael E, Greenawalt, Danielle M, Hellmann, Matthew D, Awad, Mark M, Gainor, Justin F, Schrock, Alexa B, Hartmaier, Ryan J, Trabucco, Sally E, Gay, Laurie, Ali, Siraj M, Elvin, Julia A, Singal, Gaurav, Ross, Jeffrey S, Fabrizio, David, Szabo, Peter M, Chang, Han, Sasson, Ariella, Srinivasan, Sujaya, Kirov, Stefan, Szustakowski, Joseph, Vitazka, Patrik, Edwards, Robin, Bufill, Jose A, Sharma, Neelesh, Ou, Sai-Hong I, Peled, Nir, Spigel, David R, Rizvi, Hira, Aguilar, Elizabeth Jimenez, Carter, Brett W, Erasmus, Jeremy, Halpenny, Darragh F, Plodkowski, Andrew J, Long, Niamh M, Nishino, Mizuki, Denning, Warren L, Galan-Cobo, Ana, Hamdi, Haifa, Hirz, Taghreed, Tong, Pan, Wang, Jing, Rodriguez-Canales, Jaime, Villalobos, Pamela A, Parra, Edwin R, Kalhor, Neda, Sholl, Lynette M, Sauter, Jennifer L, Jungbluth, Achim A, Mino-Kenudson, Mari, Azimi, Roxana, Elamin, Yasir Y, Zhang, Jianjun, Leonardi, Giulia C, Jiang, Fei, Wong, Kwok-Kin, Lee, J Jack, Papadimitrakopoulou, Vassiliki A, Wistuba, Ignacio I, Miller, Vincent A, Frampton, Garrett M, Wolchok, Jedd D, Shaw, Alice T, Jänne, Pasi A, Stephens, Philip J, Rudin, Charles M, Geese, William J, Albacker, Lee A, Heymach, John V
Published in Cancer discovery (01.07.2018)
Published in Cancer discovery (01.07.2018)
Get full text
Journal Article
IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma
Biffi, Giulia, Oni, Tobiloba E, Spielman, Benjamin, Hao, Yuan, Elyada, Ela, Park, Youngkyu, Preall, Jonathan, Tuveson, David A
Published in Cancer discovery (01.02.2019)
Published in Cancer discovery (01.02.2019)
Get full text
Journal Article
A Phase I Trial of Regional Mesothelin-Targeted CAR T-cell Therapy in Patients with Malignant Pleural Disease, in Combination with the Anti-PD-1 Agent Pembrolizumab
Adusumilli, Prasad S, Zauderer, Marjorie G, Rivière, Isabelle, Solomon, Stephen B, Rusch, Valerie W, O'Cearbhaill, Roisin E, Zhu, Amy, Cheema, Waseem, Chintala, Navin K, Halton, Elizabeth, Pineda, John, Perez-Johnston, Rocio, Tan, Kay See, Daly, Bobby, Araujo Filho, Jose A, Ngai, Daniel, McGee, Erin, Vincent, Alain, Diamonte, Claudia, Sauter, Jennifer L, Modi, Shanu, Sikder, Devanjan, Senechal, Brigitte, Wang, Xiuyan, Travis, William D, Gönen, Mithat, Rudin, Charles M, Brentjens, Renier J, Jones, David R, Sadelain, Michel
Published in Cancer discovery (01.11.2021)
Published in Cancer discovery (01.11.2021)
Get full text
Journal Article
Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15 + Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy
Dominguez, Claudia X, Müller, Sören, Keerthivasan, Shilpa, Koeppen, Hartmut, Hung, Jeffrey, Gierke, Sarah, Breart, Beatrice, Foreman, Oded, Bainbridge, Travis W, Castiglioni, Alessandra, Senbabaoglu, Yasin, Modrusan, Zora, Liang, Yuxin, Junttila, Melissa R, Klijn, Christiaan, Bourgon, Richard, Turley, Shannon J
Published in Cancer discovery (01.02.2020)
Published in Cancer discovery (01.02.2020)
Get full text
Journal Article
β-Catenin Activation Promotes Immune Escape and Resistance to Anti-PD-1 Therapy in Hepatocellular Carcinoma
Ruiz de Galarreta, Marina, Bresnahan, Erin, Molina-Sánchez, Pedro, Lindblad, Katherine E, Maier, Barbara, Sia, Daniela, Puigvehi, Marc, Miguela, Verónica, Casanova-Acebes, María, Dhainaut, Maxime, Villacorta-Martin, Carlos, Singhi, Aatur D, Moghe, Akshata, von Felden, Johann, Tal Grinspan, Lauren, Wang, Shuang, Kamphorst, Alice O, Monga, Satdarshan P, Brown, Brian D, Villanueva, Augusto, Llovet, Josep M, Merad, Miriam, Lujambio, Amaia
Published in Cancer discovery (01.08.2019)
Published in Cancer discovery (01.08.2019)
Get full text
Journal Article