Novel Poly(ADP-ribose) Polymerase-1 Inhibitor, AG14361, Restores Sensitivity to Temozolomide in Mismatch Repair-Deficient Cells
CURTIN, Nicola J, WANG, Lan-Zhen, NEWELL, David R, YIAKOUVAKI, Anthie, KYLE, Suzanne, ARRIS, Christine A, CANAN-KOCH, Stacie, WEBBER, Stephen E, DURKACZ, Barbara W, CALVERT, Hilary A, HOSTOMSKY, Zdenek
Published in Clinical cancer research (01.02.2004)
Published in Clinical cancer research (01.02.2004)
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Novel Tricyclic Poly(ADP-ribose) Polymerase-1 Inhibitors with Potent Anticancer Chemopotentiating Activity: Design, Synthesis, and X-ray Cocrystal Structure
Canan Koch, Stacie S, Thoresen, Lars H, Tikhe, Jayashree G, Maegley, Karen A, Almassy, Robert J, Li, Jianke, Yu, Xiao-Hong, Zook, Scott E, Kumpf, Robert A, Zhang, Cathy, Boritzki, Theodore J, Mansour, Rena N, Zhang, Kanyin E, Ekker, Anne, Calabrese, Chris R, Curtin, Nicola J, Kyle, Suzanne, Thomas, Huw D, Wang, Lan-Zhen, Calvert, A. Hilary, Golding, Bernard T, Griffin, Roger J, Newell, David R, Webber, Stephen E, Hostomsky, Zdenek
Published in Journal of medicinal chemistry (07.11.2002)
Published in Journal of medicinal chemistry (07.11.2002)
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Identification of the First Retinoid X Receptor Homodimer Antagonist
Canan Koch, Stacie S, Dardashti, Laura J, Hebert, Jonathan J, White, Steven K, Croston, Glenn E, Flatten, Karen S, Heyman, Richard A, Nadzan, Alex M
Published in Journal of medicinal chemistry (16.08.1996)
Published in Journal of medicinal chemistry (16.08.1996)
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Activation of specific RXR heterodimers by an antagonist of RXR homodimers
Lala, Deepak S, Mukherjee, Ranjan, Schulman, Ira G, Koch, Stacie S. Canan, Dardashti, Laura J, Nadzan, Alex M, Croston, Glenn E, Evans, Ronald M, Heyman, Richard A
Published in Nature (London) (03.10.1996)
Published in Nature (London) (03.10.1996)
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Aza-retinoids as novel retinoid X receptor-specific agonists
Farmer, Luc J., Marron, Kristen S., Canan Koch, Stacie S., Hwang, C.K., Kallel, E Adam, Zhi, Lin, Nadzan, Alex M., Robertson, Dave W., Bennani, Youssef L.
Published in Bioorganic & medicinal chemistry letters (01.05.2006)
Published in Bioorganic & medicinal chemistry letters (01.05.2006)
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Synthesis of Retinoid X Receptor-Specific Ligands That Are Potent Inducers of Adipogenesis in 3T3-L1 Cells
Canan Koch, Stacie S, Dardashti, Laura J, Cesario, Rosemary M, Croston, Glenn E, Boehm, Marcus F, Heyman, Richard A, Nadzan, Alex M
Published in Journal of medicinal chemistry (25.02.1999)
Published in Journal of medicinal chemistry (25.02.1999)
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Synthesis and structure-activity relationships of potent retinoid X receptor ligands
Farmer, Luc J., Jeong, Susan, Kallel, E.Adam, Canan Koch, Stacie S., Croston, Glenn E., Flatten, Karen S., Heyman, Rich A., Nadzan, Alex M.
Published in Bioorganic & medicinal chemistry letters (23.09.1997)
Published in Bioorganic & medicinal chemistry letters (23.09.1997)
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Tricyclic inhibitors of poly(adp-ribose) polymerases
CANAN-KOCH STACIE S, WEBBER STEPHEN EVAN, THORESEN LARS HENRIK, TIKHE JAYASHREE
Year of Publication 28.11.2014
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Year of Publication 28.11.2014
Patent
TRICYCLIC INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASES
TIKHE, JAYASHREE, WEBBER, STEPHEN EVAN, CANAN-KOCH, STACIE S, THORESEN, LARS HENRIK
Year of Publication 10.07.2012
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Year of Publication 10.07.2012
Patent
TRICYCLIC INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASES
CANAN-KOCH STACIE S, WEBBER STEPHEN EVAN, THORESEN LARS HENRIK, TIKHE JAYASHREE
Year of Publication 31.01.2012
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Year of Publication 31.01.2012
Patent
Tricyclic compound, its thereof and pharmaceutical composition containing thereof
TIKHE JAYASHREE GIRISH, CANAN-KOCH STACIE S, WEBBER STEPHEN EVAN, THORESEN LARS HENRIK
Year of Publication 07.07.2010
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Year of Publication 07.07.2010
Patent
TRICYCLIC INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASES
TIKHE JAYASHREE GIRISH, CANAN-KOCH STACIE S, WEBBER STEPHEN EVAN, THORESEN LARS HENRIK
Year of Publication 31.10.2008
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Year of Publication 31.10.2008
Patent
Tricyclic inhibitors of poly(ADP-ribose) polymerases
CANAN-KOCH STACIE S, WEBBER STEPHEN EVAN, THORESEN LARS HENRIK, TIKHE JAYASHREE
Year of Publication 30.09.2008
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Year of Publication 30.09.2008
Patent
Tricyclic inhibitors of poly(ADP-ribose) polymerases
Webber, Stephen Evan, Canan-Koch, Stacie S, Tikhe, Jayashree, Thoresen, Lars Henrik
Year of Publication 30.09.2008
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Year of Publication 30.09.2008
Patent