Podocalyxin is required for maintaining blood–brain barrier function during acute inflammation
Cait, Jessica, Hughes, Michael R., Zeglinski, Matthew R., Chan, Allen W., Osterhof, Sabrina, Scott, R. Wilder, Hernaez, Diana Canals, Cait, Alissa, Vogl, A. Wayne, Bernatchez, Pascal, Underhill, T. Michael, Granville, David J., Murphy, Timothy H., Roskelley, Calvin D., McNagny, Kelly M.
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2019)
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Journal Article
Targeting a Tumor-Specific Epitope on Podocalyxin Increases Survival in Human Tumor Preclinical Models
Canals Hernaez, Diana, Hughes, Michael R, Li, Yicong, Mainero Rocca, Ilaria, Dean, Pamela, Brassard, Julyanne, Bell, Erin M, Samudio, Ismael, Mes-Masson, Anne-Marie, Narimatsu, Yoshiki, Clausen, Henrik, Blixt, Ola, Roskelley, Calvin D, McNagny, Kelly M
Published in Frontiers in oncology (04.05.2022)
Published in Frontiers in oncology (04.05.2022)
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Journal Article
IL-22 Preserves Gut Epithelial Integrity and Promotes Disease Remission during Chronic Salmonella Infection
Lo, Bernard C, Shin, Samuel B, Canals Hernaez, Diana, Refaeli, Ido, Yu, Hong B, Goebeler, Verena, Cait, Alissa, Mohn, William W, Vallance, Bruce A, McNagny, Kelly M
Published in The Journal of immunology (1950) (01.02.2019)
Published in The Journal of immunology (1950) (01.02.2019)
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Journal Article
The Transcription Factor RORα Preserves ILC3 Lineage Identity and Function during Chronic Intestinal Infection
Lo, Bernard C, Canals Hernaez, Diana, Scott, R Wilder, Hughes, Michael R, Shin, Samuel B, Underhill, T Michael, Takei, Fumio, McNagny, Kelly M
Published in The Journal of immunology (1950) (15.12.2019)
Published in The Journal of immunology (1950) (15.12.2019)
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Journal Article
Podocalyxin enhances breast tumor growth and metastasis and is a target for monoclonal antibody therapy
Snyder, Kimberly A, Hughes, Michael R, Hedberg, Bradley, Brandon, Jill, Hernaez, Diana Canals, Bergqvist, Peter, Cruz, Frederic, Po, Kelvin, Graves, Marcia L, Turvey, Michelle E, Nielsen, Julie S, Wilkins, John A, McColl, Shaun R, Babcook, John S, Roskelley, Calvin D, McNagny, Kelly M
Published in Breast cancer research : BCR (27.03.2015)
Published in Breast cancer research : BCR (27.03.2015)
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Journal Article
A tumor-restricted glycoform of podocalyxin is a highly selective marker of immunologically cold high-grade serous ovarian carcinoma
Brassard, Julyanne, Hughes, Michael R, Dean, Pamela, Hernaez, Diana Canals, Thornton, Shelby, Banville, Allyson C, Smazynski, Julian, Warren, Mary, Zhang, Kevin, Milne, Katy, Gilks, C Blake, Mes-Masson, Anne-Marie, Huntsman, David G, Nelson, Brad H, Roskelley, Calvin D, McNagny, Kelly M
Published in Frontiers in oncology (2023)
Published in Frontiers in oncology (2023)
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Journal Article
PODO447: a novel antibody to a tumor-restricted epitope on the cancer antigen podocalyxin
Canals Hernaez, Diana, Hughes, Michael R, Dean, Pamela, Bergqvist, Peter, Samudio, Ismael, Blixt, Ola, Wiedemeyer, Katharina, Li, Yicong, Bond, Chris, Cruz, Eric, Köbel, Martin, Gilks, Blake, Roskelley, Calvin D, McNagny, Kelly M
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
A tumor-restricted glycoepitope of podocalyxin correlates with immune evasion in high-grade serous ovarian carcinoma
Brassard, Julyanne, Hernaez, Diana Canals, Hughes, Michael R, Milne, Katy, Dean, Pamela, Warren, Mary, Zhang, Kevin, Banville, Allyson C, Smazynski, Julian, Bond, David, Nelson, Brad H, Roskelley, Calvin D, McNagny, Kelly M
Published in The Journal of immunology (1950) (01.05.2022)
Published in The Journal of immunology (1950) (01.05.2022)
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Journal Article
Depletion of SCFA-fermenting gut bacteria alters the epigenome of hematopoietic stem and progenitor cells
Hughes, Michael R, Cait, Alissa, Bilenky, Misha, Moksa, Michelle M., Yip, William, Li, Kristen, Canals-Hernaez, Diana, Hirst, Martin, Mohn, William W, McNagny, Kelly M
Published in The Journal of immunology (1950) (01.05.2020)
Published in The Journal of immunology (1950) (01.05.2020)
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Journal Article
Abstract 2657: Preclinical model to evaluate the safety and efficacy of PODO83: A monoclonal antibody against podocalyxin that targets tumor growth and metastasis
Brassard, Julyanne, Hughes, Michael R., Dean, Pamela, Hernaez, Diana Canals, Schwab, Janella, Lau, Yasmine, Roskelley, Calvin D., McNagny, Kelly M.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract 1134: Therapeutic potential of an antibody-drug conjugate directed against a tumor-specific epitope on podocalyxin
Dean, Pamela M. Austin, Hernaez, Diana Canals, Brassard, Julyanne, Hughes, Michael R., Bell, Erin M., McNagny, Kelly M., Roskelley, Calvin D.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Declined presentation: Podocalyxin regulates CXCR4-dependent hematopoietic stem cell trafficking and engraftment
Hughes, Michael, Lo, Bernard, Antignano, Frann, Nielsen, Julie, Cait, Jessie, Hernaez, Diana Canals, Tan, Poh, McNagny, Kelly
Published in Experimental hematology (01.08.2013)
Published in Experimental hematology (01.08.2013)
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Journal Article
Declined presentation
Hughes, Michael, Lo, Bernard, Antignano, Frann, Nielsen, Julie, Cait, Jessie, Hernaez, Diana Canals, Tan, Poh, McNagny, Kelly
Published in Experimental hematology (01.08.2013)
Published in Experimental hematology (01.08.2013)
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Journal Article
Abortive γδTCR rearrangements suggest ILC2s are derived from T-cell precursors
Shin, Samuel B., Lo, Bernard C., Ghaedi, Maryam, Scott, R. Wilder, Li, Yicong, Messing, Melina, Hernaez, Diana Canals, Cait, Jessica, Murakami, Taka, Hughes, Michael R., Leslie, Kevin B., Underhill, T. Michael, Takei, Fumio, McNagny, Kelly M.
Published in Blood advances (10.11.2020)
Published in Blood advances (10.11.2020)
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Journal Article
Anti-podocalyxin antibodies and methods of using the same
Hughes, Michael R, McNagny, Kelley Marshall, Bergqvist, Jan Peter, Bond, Christopher John, Dean, Pamela Megan, Roskelley, Calvin D, Canals Hernaez, Diana, Blixt, Klas Ola, MacDonald, Katherine Grace, Samudio, Ismael, Babcook, John Stephen, Von Rossum, Anna, Hedberg, Bradley John
Year of Publication 06.08.2024
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Year of Publication 06.08.2024
Patent
Anti-podocalyxin antibodies and methods of using the same
Blixt, Klas Ola, Hughes, Michael R, McNagny, Kelly Marshall, Samudio, Ismael, Babcook, John Stephen, Bergqvist, Jan Peter, Bond, Christopher John, Hernaez, Diana Canals, Von Rossum, Anna, Hedberg, Bradley John, Roskelley, Calvin D, Macdonald, Katherine Grace
Year of Publication 24.08.2023
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Year of Publication 24.08.2023
Patent
ANTI-PODOCALYXIN ANTIBODIES AND METHODS OF USING THE SAME
BERGQVIST, Jan Peter, VON ROSSUM, Anna, BABCOOK, John Stephen, DEAN, Pamela Megan, ROSKELLEY, Calvin D, CANALS HERNAEZ, Diana, MCNAGNY, Kelley Marshall, HEDBERG, Bradley John, HUGHES, Michael R, BOND, Christopher John, BLIXT, Klas Ola, SAMUDIO, Ismael, MACDONALD, Katherine Grace
Year of Publication 15.09.2022
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Year of Publication 15.09.2022
Patent