Specific and selective induction of miR-124 in immune cells by the quinoline ABX464: a transformative therapy for inflammatory diseases
Tazi, Jamal, Begon-Pescia, Christina, Campos, Noëlie, Apolit, Cécile, Garcel, Aude, Scherrer, Didier
Published in Drug discovery today (01.04.2021)
Published in Drug discovery today (01.04.2021)
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Journal Article
Both anti-inflammatory and antiviral properties of novel drug candidate ABX464 are mediated by modulation of RNA splicing
Vautrin, Audrey, Manchon, Laurent, Garcel, Aude, Campos, Noëlie, Lapasset, Laure, Laaref, Abdelhamid Mahdi, Bruno, Roman, Gislard, Marie, Dubois, Emeric, Scherrer, Didier, Ehrlich, J Hartmut, Tazi, Jamal
Published in Scientific reports (28.01.2019)
Published in Scientific reports (28.01.2019)
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Journal Article
The Anti-Hiv Candidate Abx464 Dampens Intestinal Inflammation by Triggering Il-22 Production in Activated Macrophages
Chebli, Karim, Papon, Laura, Paul, Conception, Garcel, Aude, Campos, Noëlie, Scherrer, Didier, J Ehrlich, Hartmut, Hahne, Michael, Tazi, Jamal
Published in Scientific reports (07.07.2017)
Published in Scientific reports (07.07.2017)
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Journal Article
Reversing HIV latency via sphingosine-1-phosphate receptor 1 signaling
Duquenne, Charline, Gimenez, Sandrine, Guigues, Adeline, Viala, Benjamin, Boulouis, Caroline, Mettling, Clément, Maurel, Damien, Campos, Noëlie, Doumazane, Etienne, Comps-agrar, Laetitia, Tazi, Jamal, Prézeau, Laurent, Corbeau, Pierre, François, Vincent
Published in AIDS (London) (28.11.2017)
Published in AIDS (London) (28.11.2017)
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Journal Article
Sa1238 OBEFAZIMOD REDUCES TOTAL NUMBER OF TUMORS AND HIGH-GRADE ADENOMAS IN A MURINE COLITIS ASSOCIATED COLORECTAL CANCER MODEL
Apolit, Cécile, Lemmers, Bénédicte, Lattanzio, Rossano, Campos, Noélie, Scherrer, Didier, Hahne, Michael, Garcel, Aude
Published in Gastroenterology (New York, N.Y. 1943) (18.05.2024)
Published in Gastroenterology (New York, N.Y. 1943) (18.05.2024)
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Journal Article
Long lasting control of viral rebound with a new drug ABX464 targeting Rev - mediated viral RNA biogenesis
Campos, Noëlie, Myburgh, Renier, Garcel, Aude, Vautrin, Audrey, Lapasset, Laure, Nadal, Erika Schläpfer, Mahuteau-Betzer, Florence, Najman, Romain, Fornarelli, Pauline, Tantale, Katjana, Basyuk, Eugénia, Séveno, Martial, Venables, Julian P, Pau, Bernard, Bertrand, Edouard, Wainberg, Mark A, Speck, Roberto F, Scherrer, Didier, Tazi, Jamal
Published in Retrovirology (09.04.2015)
Published in Retrovirology (09.04.2015)
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Journal Article
Protection against high-dose highly pathogenic mucosal SIV challenge at very low serum neutralizing titers of the antibody-like molecule CD4-IgG2
Poignard, Pascal, Moldt, Brian, Maloveste, Karla, Campos, Noëlie, Olson, William C, Rakasz, Eva, Watkins, David I, Burton, Dennis R
Published in PloS one (27.07.2012)
Published in PloS one (27.07.2012)
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Journal Article
ABX464 (Obefazimod) Upregulates miR-124 to Reduce Proinflammatory Markers in Inflammatory Bowel Diseases
Apolit, Cécile, Campos, Noëlie, Vautrin, Audrey, Begon-Pescia, Christina, Lapasset, Laure, Scherrer, Didier, Gineste, Paul, Ehrlich, Hartmut, Garcel, Aude, Santo, Julien, Tazi, Jamal
Published in Clinical and translational gastroenterology (01.04.2023)
Published in Clinical and translational gastroenterology (01.04.2023)
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Journal Article
RNA sequencing analysis of activated macrophages treated with the anti-HIV ABX464 in intestinal inflammation
Manchon, Laurent, Chebli, Karim, Papon, Laura, Paul, Conception, Garcel, Aude, Campos, Noëlie, Scherrer, Didier, Ehrlich, Hartmut, Hahne, Michael, Tazi, Jamal
Published in Scientific data (17.10.2017)
Published in Scientific data (17.10.2017)
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Journal Article
Targeting Long Non-Coding RNA splicing by novel candidate drug
Manchon, Laurent, Vautrin, Audrey, Tazi, Jamal, Garcel, Aude, Campos, Noelie
Published in 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (01.11.2019)
Published in 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (01.11.2019)
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Conference Proceeding
PREPARATION OF COMPOUNDS USEFUL FOR TREATING AIDS
SCHERRER, Didier, GARCEL, Aude, NAJMAN, Romain, TAZI, Jamal, CAMPOS, Noëlie, MAHUTEAU-BETZER, Florence
Year of Publication 21.06.2023
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Year of Publication 21.06.2023
Patent
QUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OR PREVENTION OF VIRAL INFECTION
GARCEL, AUDE, VAUTRIN, AUDREY, TAZI, JAMAL, FORNARELLI, PAULINE, SCHERRER, DIDIER, MAHUTEAU, FLORENCE, CAMPOS, NOELIE, NAJMAN, ROMAIN
Year of Publication 13.12.2022
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Year of Publication 13.12.2022
Patent