A high-throughput screen for TMPRSS2 expression identifies FDA-approved compounds that can limit SARS-CoV-2 entry
Chen, Yanwen, Lear, Travis B, Evankovich, John W, Larsen, Mads B, Lin, Bo, Alfaras, Irene, Kennerdell, Jason R, Salminen, Laura, Camarco, Daniel P, Lockwood, Karina C, Tuncer, Ferhan, Liu, Jie, Myerburg, Michael M, McDyer, John F, Liu, Yuan, Finkel, Toren, Chen, Bill B
Published in Nature communications (23.06.2021)
Published in Nature communications (23.06.2021)
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E3 ubiquitin ligase ZBTB25 suppresses beta coronavirus infection through ubiquitination of the main viral protease MPro
Lear, Travis B., Boudreau, Áine N., Lockwood, Karina C., Chu, Elise, Camarco, Daniel P., Cao, Qing, Nguyen, Matthew, Evankovich, John W., Finkel, Toren, Liu, Yuan, Chen, Bill B.
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Published in The Journal of biological chemistry (01.12.2023)
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The Generation of Three-Dimensional Head and Neck Cancer Models for Drug Discovery in 384-Well Ultra-Low Attachment Microplates
Close, David A, Camarco, Daniel P, Shan, Feng, Kochanek, Stanton J, Johnston, Paul A
Published in Methods in molecular biology (Clifton, N.J.) (2018)
Published in Methods in molecular biology (Clifton, N.J.) (2018)
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High-Content Screening Comparison of Cancer Drug Accumulation and Distribution in Two-Dimensional and Three-Dimensional Culture Models of Head and Neck Cancer
Shan, Feng, Close, David A, Camarco, Daniel P, Johnston, Paul A
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Published in Assay and drug development technologies (01.01.2018)
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Total Synthesis and Biological Evaluation of Tubulysin Analogues
Colombo, Raffaele, Wang, Zhiyong, Han, Junyan, Balachandran, Raghavan, Daghestani, Hikmat N, Camarco, Daniel P, Vogt, Andreas, Day, Billy W, Mendel, David, Wipf, Peter
Published in Journal of organic chemistry (04.11.2016)
Published in Journal of organic chemistry (04.11.2016)
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A small molecule NRF2 activator BC-1901S ameliorates inflammation through DCAF1/NRF2 axis
Chen, Yanwen, Evankovich, John W., Lear, Travis B., Tuncer, Ferhan, Kennerdell, Jason R., Camarco, Daniel P., Shishido, Morgan S., Liu, Yuan, Chen, Bill B.
Published in Redox biology (01.05.2020)
Published in Redox biology (01.05.2020)
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Streamlined Syntheses of (−)-Dictyostatin, 16-Desmethyl-25,26-dihydrodictyostatin, and 6-epi-16-Desmethyl-25,26-dihydrodictyostatin
Zhu, Wei, Jiménez, María, Jung, Won-Hyuk, Camarco, Daniel P, Balachandran, Raghavan, Vogt, Andreas, Day, Billy W, Curran, Dennis P
Published in Journal of the American Chemical Society (07.07.2010)
Published in Journal of the American Chemical Society (07.07.2010)
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High Content Imaging Assays for IL-6-Induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines
Johnston, Paul A, Sen, Malabika, Hua, Yun, Camarco, Daniel P, Shun, Tong Ying, Lazo, John S, Grandis, Jennifer R
Published in Methods in molecular biology (Clifton, N.J.) (2018)
Published in Methods in molecular biology (Clifton, N.J.) (2018)
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Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors
LaPorte, Matthew G., Wang, Zhuzhu, Colombo, Raffaele, Garzan, Atefeh, Peshkov, Vsevolod A., Liang, Mary, Johnston, Paul A., Schurdak, Mark E., Sen, Malabika, Camarco, Daniel P., Hua, Yun, Pollock, Netanya I., Lazo, John S., Grandis, Jennifer R., Wipf, Peter, Huryn, Donna M.
Published in Bioorganic & medicinal chemistry letters (01.08.2016)
Published in Bioorganic & medicinal chemistry letters (01.08.2016)
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Maximizing the Value of Cancer Drug Screening in Multicellular Tumor Spheroid Cultures: A Case Study in Five Head and Neck Squamous Cell Carcinoma Cell Lines
Kochanek, Stanton J., Close, David A., Camarco, Daniel P., Johnston, Paul A.
Published in SLAS discovery (01.04.2020)
Published in SLAS discovery (01.04.2020)
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High-Content Screening Campaign to Identify Compounds That Inhibit or Disrupt Androgen Receptor-Transcriptional Intermediary Factor 2 Protein-Protein Interactions for the Treatment of Prostate Cancer
Fancher, Ashley T, Hua, Yun, Camarco, Daniel P, Close, David A, Strock, Christopher J, Johnston, Paul A
Published in Assay and drug development technologies (01.08.2018)
Published in Assay and drug development technologies (01.08.2018)
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Development and Implementation of a High-Throughput High-Content Screening Assay to Identify Inhibitors of Androgen Receptor Nuclear Localization in Castration-Resistant Prostate Cancer Cells
Johnston, Paul A, Nguyen, Minh M, Dar, Javid A, Ai, Junkui, Wang, Yujuan, Masoodi, Khalid Z, Shun, Tongying, Shinde, Sunita, Camarco, Daniel P, Hua, Yun, Huryn, Donna M, Wilson, Gabriela Mustata, Lazo, John S, Nelson, Joel B, Wipf, Peter, Wang, Zhou
Published in Assay and drug development technologies (01.05.2016)
Published in Assay and drug development technologies (01.05.2016)
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Reconfiguring the AR-TIF2 Protein-Protein Interaction HCS Assay in Prostate Cancer Cells and Characterizing the Hits from a LOPAC Screen
Fancher, Ashley T, Hua, Yun, Camarco, Daniel P, Close, David A, Strock, Christopher J, Johnston, Paul A
Published in Assay and drug development technologies (01.10.2016)
Published in Assay and drug development technologies (01.10.2016)
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HCS campaign to identify selective inhibitors of IL-6-induced STAT3 pathway activation in head and neck cancer cell lines
Johnston, Paul A, Sen, Malabika, Hua, Yun, Camarco, Daniel P, Shun, Tong Ying, Lazo, John S, Wilson, Gabriela Mustata, Resnick, Lynn O, LaPorte, Matthew G, Wipf, Peter, Huryn, Donna M, Grandis, Jennifer R
Published in Assay and drug development technologies (01.09.2015)
Published in Assay and drug development technologies (01.09.2015)
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A simplified synthesis of novel dictyostatin analogues with in vitro activity against epothilone B-resistant cells and antiangiogenic activity in zebrafish embryos
Vollmer, Laura L, Jiménez, Maria, Camarco, Daniel P, Zhu, Wei, Daghestani, Hikmat N, Balachandran, Raghavan, Reese, Celeste E, Lazo, John S, Hukriede, Neil A, Curran, Dennis P, Day, Billy W, Vogt, Andreas
Published in Molecular cancer therapeutics (01.06.2011)
Published in Molecular cancer therapeutics (01.06.2011)
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Mechanism of action of selective inhibitors of IL-6 induced STAT3 pathway in head and neck cancer cell lines
Sen, Malabika, Johnston, Paul A., Pollock, Netanya I., DeGrave, Kara, Joyce, Sonali C., Freilino, Maria L., Hua, Yun, Camarco, Daniel P., Close, David A., Huryn, Donna M., Wipf, Peter, Grandis, Jennifer R.
Published in Journal of chemical biology (01.07.2017)
Published in Journal of chemical biology (01.07.2017)
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Journal Article
A high throughput screen for TMPRSS2 expression identifies FDA-approved and clinically advanced compounds that can limit SARS-CoV-2 entry
Chen, Yanwen, Lear, Travis B, Evankovich, John W, Larsen, Mads B, Lin, Bo, Alfaras, Irene, Kennerdell, Jason R, Salminen, Laura, Camarco, Daniel P, Lockwood, Karina C, Liu, Jie, Myerburg, Michael M, McDyer, John F, Liu, Yuan, Finkel, Toren, Chen, Bill B
Published in Research square (14.08.2020)
Published in Research square (14.08.2020)
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Modulation of lysosomal function as a therapeutic approach for coronaviral infections
Lear, Travis, Larsen, Mads, Lin, Bo, Cao, Qing, Alfaras, Irene, Kennerdell, Jason, Salminen, Laura, Camarco, Daniel, Lockwood, Karina C, Boudreau, Áine, Ma, Jing, Liu, Jie, Tan, Jay X, Myerburg, Michael M, Chen, Yanwen, St Croix, Claudette, Sekine, Yusuke, Evankovich, John, Finkel, Toren, Chen, Bill B, Liu, Yuan
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
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Abstract 1619: Generation of a novel estrogen receptor degrader
Liu, Yuan, Kennerdell, Jason R., Lin, Bo, Larsen, Mads B., Alfaras, Irene, Camarco, Daniel P., Tuncer, Ferhan, Finkel, Toren, Chen, Bill B.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 1805: Identification of a small molecule that induces targeted protein degradation of ADAR1
Liu, Yuan, Larsen, Mads B., Lin, Bo, Kennerdell, Jason R., Alfaras, Irene, Camarco, Daniel P., Tuncer, Ferhan, Finkel, Toren, Chen, Bill B.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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