Loss of AMPKα2 Impairs Hedgehog-Driven Medulloblastoma Tumorigenesis
Zhang, Honglai, Kuick, Rork, Park, Sung-Soo, Peabody, Claire, Yoon, Justin, Fernández, Ester Calvo, Wang, Junying, Thomas, Dafydd, Viollet, Benoit, Inoki, Ken, Camelo-Piragua, Sandra, Rual, Jean-François
Published in International journal of molecular sciences (23.10.2018)
Published in International journal of molecular sciences (23.10.2018)
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Journal Article
Racing to immunity: Journey to a COVID‐19 vaccine and lessons for the future
Calvo Fernández, Ester, Zhu, Lucie Y.
Published in British journal of clinical pharmacology (01.09.2021)
Published in British journal of clinical pharmacology (01.09.2021)
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Journal Article
Targeted delivery of napabucasin with radiotherapy improves outcomes in diffuse midline glioma
Gallitto, Matthew, Zhang, Xu, De Los Santos, Genesis, Wei, Hong-Jian, Fernández, Ester Calvo, Duan, Shoufu, Sedor, Geoffrey, Yoh, Nina, Kokosi, Danae, Angel, J Carlos, Wang, Yi-Fang, White, Erin, Kinslow, Connor J, Berg, Xander, Tomassoni, Lorenzo, Zandkarimi, Fereshteh, Chio, Iok In Christine, Canoll, Peter D, Bruce, Jeffrey N, Feldstein, Neil A, Gartrell, Robyn D, Cheng, Simon, Garvin, James H, Zacharoulis, Stergios, Wechsler-Reya, Robert J, Pavisic, Jovana, Califano, Andrea, Zhang, Zhiguo, Wu, Cheng-Chia
Published in Neuro-oncology (Charlottesville, Va.) (12.10.2024)
Published in Neuro-oncology (Charlottesville, Va.) (12.10.2024)
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Journal Article
DIPG-57. A systems biology approach to defining and targeting master regulator dependencies from bulk and single-Cell RNA-seq in diffuse midline glioma (DMG)
Fernández, Ester Calvo, Wang, Junqiang, Griffin, Aaron, Minns, Hanna, Wei, Hong-Jian, Zhang, Xu, Szalontay, Luca, Mundi, Prabhjot, Wu, Cheng-Chia, Gartrell, Robyn, Zacharoulis, Stergios, Califano, Andrea, Pavisic, Jovana
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
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Journal Article
DIPG-49. A SYSTEMS BIOLOGY APPROACH TO DEFINING AND TARGETING CELL STATE-SPECIFIC MASTER REGULATOR DEPENDENCIES IN DIFFUSE MIDLINE GLIOMA
Fernández, Ester Calvo, Wang, Junqiang, Zhang, Xu, Wei, Hong-Jian, Minns, Hanna, Griffin, Aaron, Obradovic, Aleksandar, Vlahos, Lukas, Martins, Timothy, Becker, Pamela, Crawford, John, Gartrell, Robyn, Szalontay, Luca, Zacharoulis, Stergios, Zhang, Zhiguo, Wechsler-Reya, Robert, Wu, Cheng-Chia, Califano, Andrea, Pavisic, Jovana
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
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Journal Article
Abstract 486: A systems biology approach to defining tumor heterogeneity, prognostic and targetable master regulator protein signatures from bulk and single cell RNA-seq in diffuse midline glioma (DMG)
Fernández, Ester Calvo, Wang, Junqiang, Griffin, Aaron T., Szalontay, Luca, Zacharoulis, Stergios, Pavisic, Jovana, Califano, Andrea
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Abstract 6516: Single-cell protein activity inference reveals lymphocytic immune infiltration in diffuse intrinsic pontine glioma induced by focused ultrasound
White, Erin, Wei, Hong-Jian, Fernández, Ester Calvo, Minns, Hanna, Pavisic, Jovana, Gartrell, Robyn, Wu, Cheng-Chia, Califano, Andrea, Obradovic, Aleksandar
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
CSIG-20. L3MBTL3 SUPPRESSES MEDULLOBLASTOMA TUMORIGENESIS THROUGH MODULATION OF THE NOTCH/RBPJ SIGNALING PATHWAY
Zhang, Honglai, Xu, Tao, Peabody, Claire, Fernández, Ester Calvo, Budhathoki, Rashmi, Huang, Philip Chi-En, Hughes, Elizabeth D, Saunders, Thomas L, Kuick, Rork, Magnuson, Brian, Camelo-Piragua, Sandra, Rual, Jean-François
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
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Journal Article
Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulators
Obradovic, Aleksandar, Ager, Casey, Turunen, Mikko, Nirschl, Thomas, Khosravi-Maharlooei, Mohsen, Iuga, Alina, Jackson, Christopher M., Yegnasubramanian, Srinivasan, Tomassoni, Lorenzo, Fernandez, Ester Calvo, McCann, Patrick, Rogava, Meri, DeMarzo, Angelo M., Kochel, Christina M., Allaf, Mohamad, Bivalacqua, Trinity, Lim, Michael, Realubit, Ronald, Karan, Charles, Drake, Charles G., Califano, Andrea
Published in Cancer cell (08.05.2023)
Published in Cancer cell (08.05.2023)
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Journal Article
Abstract 3658: Characterization of the role of L3MBTL3 in medulloblastoma tumorigenesis
Zhang, Honglai, Fernandez, Ester Calvo, Peabody, Claire, Kuick, Rork, Park, Sung-Soo, Saunders, Thomas, Camelo-Piragua, Sandra, Rual, Jean-Francois M.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
MEDU-03. CHARACTERIZATION OF THE ROLE OF L3MBTL3 IN MEDULLOBLASTOMA TUMORIGENESIS
Zhang, Honglai, Fernandez, Ester Calvo, Peabody, Claire, Kuick, Rork, Park, Sung-Soo, Saunders, Thomas, Camelo-Piragua, Sandra, Rual, Jeff-Francois
Published in Neuro-oncology (Charlottesville, Va.) (23.04.2019)
Published in Neuro-oncology (Charlottesville, Va.) (23.04.2019)
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Journal Article
Elucidation and Pharmacologic Targeting of Master Regulator Dependencies in Coexisting Diffuse Midline Glioma Subpopulations
Fernández, Ester Calvo, Tomassoni, Lorenzo, Zhang, Xu, Wang, Junqiang, Obradovic, Aleksandar, Laise, Pasquale, Griffin, Aaron T, Vlahos, Lukas, Minns, Hanna E, Morales, Diana V, Simmons, Christian, Gallitto, Matthew, Wei, Hong-Jian, Martins, Timothy J, Becker, Pamela S, Crawford, John R, Tzaridis, Theophilos, Wechsler-Reya, Robert J, Garvin, James, Gartrell, Robyn D, Szalontay, Luca, Zacharoulis, Stergios, Wu, Cheng-Chia, Zhang, Zhiguo, Califano, Andrea, Pavisic, Jovana
Published in bioRxiv : the preprint server for biology (17.03.2024)
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Published in bioRxiv : the preprint server for biology (17.03.2024)
Journal Article
MODL-24. Focused ultrasound-mediated blood-brain barrier opening and panobinostat in a thalamic syngeneic murine DMG model is feasible and safe
Webster Carrion, Andrea, Wei, Hong-Jian, McQuillan, Nicholas, Tazhibi, Masih, Kokossis, Danae, Berg, Xander, Minns, Hanna, Zhang, Xu, Zhang, Zhiguo, Wang, Junqiang, Fernandez, Ester Calvo, Jan, Chia-Ing, Padilla, Oscar, Gartrell, Robyn D, Becher, Oren, Jr, James H Garvin, Pavisic, Jovana, Szalontay, Luca, Konofagou, Elisa E, Zacharoulis, Stergios, Wu, Cheng-Chia
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
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Journal Article
Abstract 5460: Discovery and validation of effective combination therapies targeting cell state-specific master regulator vulnerabilities by network-based protein activity inference in diffuse midline glioma
Fernandez, Ester Calvo, Tomassoni, Lorenzo, Zhang, Xu, Obradovic, Aleksandar, Laise, Pasquale, Griffin, Aaron T., Vlahos, Lukas, Wang, Junqiang, Minns, Hanna E., Morales, Diana V., Simmons, Christian, Gallito, Matthew, Wei, Hong-Jian, Zhang, Zhiguo, Gartrell, Robyn, Szalontay, Luca, Zacharoulis, Stergios, Wu, Cheng-Chia, Califano, Andrea, Pavisic, Jovana
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract 4304: Network-based inference identifies cell state-specific drugs targeting master regulator vulnerabilities in diffuse midline glioma
Fernandez, Ester Calvo, Wang, Junqiang, Zhang, Xu, Wei, Hong-Jian, Minns, Hanna E., Griffin, Aaron T., Vlahos, Lukas, Martins, Timothy J., Becker, Pamela S., Crawford, John, Gartrell, Robyn D., Szalontay, Luca, Zacharoulis, Stergios, Zhang, Zhiguo, Wechsler-Reya, Robert, Wu, Cheng-Chia, Califano, Andrea, Pavisic, Jovana
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract A007: Pancreatic cancer comprises co-existing transcriptional states regulated by distinct master regulator programs
Laise, Pasquale, Turunen, Mikko, Maurer, Hans Carlo, Garcia, Alvaro Curiel, Elyada, Ela, Schmierer, Bernhard, Tomassoni, Lorenzo, Worley, Jeremy, Alvarez, Mariano J., Kesner, Jordan, Tan, Xiangtian, Tagore, Somnath, Fernandez, Ester Calvo, Wong, Kelly, Wang, Alexander L. E., Ge, Sabrina, Iuga, Alina C., Griffin, Aaron T., Wong, Winston, Manji, Gulam A., Notta, Faiyaz, Tuveson, David A., Olive, Kenneth P. P., Califano, Andrea
Published in Cancer research (Chicago, Ill.) (15.11.2022)
Published in Cancer research (Chicago, Ill.) (15.11.2022)
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Journal Article
Interrogation of genome-wide, experimentally dissected gene regulatory networks reveals mechanisms underlying dynamic cellular state control
Tan, Xiangtian, Worley, Jeremy, Turunen, Mikko, Wong, Kelly, Ester Calvo Fernández, Paull, Evan, Jones, Sunny, Wang, Junqiang, Noh, Heeju, Salvatori, Beatrice, Chavez, Alejandro, Califano, Andrea
Published in bioRxiv (08.07.2021)
Published in bioRxiv (08.07.2021)
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Developmental and MAPK-responsive transcription factors drive distinct malignant subtypes and genetic dependencies in pancreatic cancer
Laise, Pasquale, Turunen, Mikko, Alvaro Curiel Garcia, Tomassoni, Lorenzo, Maurer, Carlo, Elyada, Ela, Schmierer, Bernhard, Worley, Jeremy, Kesner, Jordan, Tan, Xiangtian, Ester Calvo Fernandez, Wong, Kelly, Wasko, Urszula, Tagore, Somnath, Alexander Le Wang, Ge, Sabrina, Iuga, Alina Cornelia, Griffin, Aaron, Wong, Winston, Manji, Gulam, Alvarez, Mariano J, Notta, Faiyaz, Tuveson, David, Olive, Kenneth P, Califano, Andrea
Published in bioRxiv (14.11.2022)
Published in bioRxiv (14.11.2022)
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