Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions
Pietras, Eric M., Reynaud, Damien, Kang, Yoon-A., Carlin, Daniel, Calero-Nieto, Fernando J., Leavitt, Andrew D., Stuart, Joshua M., Göttgens, Berthold, Passegué, Emmanuelle
Published in Cell stem cell (02.07.2015)
Published in Cell stem cell (02.07.2015)
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Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations
Wilson, Nicola K., Kent, David G., Buettner, Florian, Shehata, Mona, Macaulay, Iain C., Calero-Nieto, Fernando J., Sánchez Castillo, Manuel, Oedekoven, Caroline A., Diamanti, Evangelia, Schulte, Reiner, Ponting, Chris P., Voet, Thierry, Caldas, Carlos, Stingl, John, Green, Anthony R., Theis, Fabian J., Göttgens, Berthold
Published in Cell stem cell (04.06.2015)
Published in Cell stem cell (04.06.2015)
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Notch ligand Dll4 impairs cell recruitment to aortic clusters and limits blood stem cell generation
Porcheri, Cristina, Golan, Ohad, Calero‐Nieto, Fernando J, Thambyrajah, Roshana, Ruiz‐Herguido, Cristina, Wang, Xiaonan, Catto, Francesca, Guillén, Yolanda, Sinha, Roshani, González, Jessica, Kinston, Sarah J, Mariani, Samanta A, Maglitto, Antonio, Vink, Chris S, Dzierzak, Elaine, Charbord, Pierre, Göttgens, Bertie, Espinosa, Lluis, Sprinzak, David, Bigas, Anna
Published in The EMBO journal (15.04.2020)
Published in The EMBO journal (15.04.2020)
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Characterization of transcriptional networks in blood stem and progenitor cells using high-throughput single-cell gene expression analysis
Moignard, Victoria, Macaulay, Iain C., Swiers, Gemma, Buettner, Florian, Schütte, Judith, Calero-Nieto, Fernando J., Kinston, Sarah, Joshi, Anagha, Hannah, Rebecca, Theis, Fabian J., Jacobsen, Sten Eirik, de Bruijn, Marella F., Göttgens, Berthold
Published in Nature cell biology (01.04.2013)
Published in Nature cell biology (01.04.2013)
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Cis inhibition of NOTCH1 through JAGGED1 sustains embryonic hematopoietic stem cell fate
Thambyrajah, Roshana, Maqueda, Maria, Neo, Wen Hao, Imbach, Kathleen, Guillén, Yolanda, Grases, Daniela, Fadlullah, Zaki, Gambera, Stefano, Matteini, Francesca, Wang, Xiaonan, Calero-Nieto, Fernando J., Esteller, Manel, Florian, Maria Carolina, Porta, Eduard, Benedito, Rui, Göttgens, Berthold, Lacaud, Georges, Espinosa, Lluis, Bigas, Anna
Published in Nature communications (21.02.2024)
Published in Nature communications (21.02.2024)
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Single-cell RNA-sequencing reveals a distinct population of proglucagon-expressing cells specific to the mouse upper small intestine
Glass, Leslie L., Calero-Nieto, Fernando J., Jawaid, Wajid, Larraufie, Pierre, Kay, Richard G., Göttgens, Berthold, Reimann, Frank, Gribble, Fiona M.
Published in Molecular metabolism (Germany) (01.10.2017)
Published in Molecular metabolism (Germany) (01.10.2017)
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Dissecting the early steps of MLL induced leukaemogenic transformation using a mouse model of AML
Basilico, Silvia, Wang, Xiaonan, Kennedy, Alison, Tzelepis, Konstantinos, Giotopoulos, George, Kinston, Sarah J., Quiros, Pedro M., Wong, Kim, Adams, David J., Carnevalli, Larissa S., Huntly, Brian J. P., Vassiliou, George S., Calero-Nieto, Fernando J., Göttgens, Berthold
Published in Nature communications (16.03.2020)
Published in Nature communications (16.03.2020)
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Key regulators control distinct transcriptional programmes in blood progenitor and mast cells
Calero-Nieto, Fernando J, Ng, Felicia S, Wilson, Nicola K, Hannah, Rebecca, Moignard, Victoria, Leal-Cervantes, Ana I, Jimenez-Madrid, Isabel, Diamanti, Evangelia, Wernisch, Lorenz, Göttgens, Berthold
Published in The EMBO journal (02.06.2014)
Published in The EMBO journal (02.06.2014)
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Integrated genome-scale analysis of the transcriptional regulatory landscape in a blood stem/progenitor cell model
Wilson, Nicola K., Schoenfelder, Stefan, Hannah, Rebecca, Sánchez Castillo, Manuel, Schütte, Judith, Ladopoulos, Vasileios, Mitchelmore, Joanna, Goode, Debbie K., Calero-Nieto, Fernando J., Moignard, Victoria, Wilkinson, Adam C., Jimenez-Madrid, Isabel, Kinston, Sarah, Spivakov, Mikhail, Fraser, Peter, Göttgens, Berthold
Published in Blood (31.03.2016)
Published in Blood (31.03.2016)
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Proteomic analysis of circulating immune cells identifies cellular phenotypes associated with COVID-19 severity
Potts, Martin, Fletcher-Etherington, Alice, Nightingale, Katie, Mescia, Federica, Bergamaschi, Laura, Calero-Nieto, Fernando J., Antrobus, Robin, Williamson, James, Parsons, Harriet, Huttlin, Edward L., Kingston, Nathalie, Göttgens, Berthold, Bradley, John R., Lehner, Paul J., Matheson, Nicholas J., Smith, Kenneth G.C., Wills, Mark R., Lyons, Paul A., Weekes, Michael P.
Published in Cell reports (Cambridge) (27.06.2023)
Published in Cell reports (Cambridge) (27.06.2023)
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Enhanced hemato-endothelial specification during human embryonic differentiation through developmental cooperation between AF4-MLL and MLL-AF4 fusions
Bueno, Clara, Calero-Nieto, Fernando J, Wang, Xiaonan, Valdés-Mas, Rafael, Gutiérrez-Agüera, Francisco, Roca-Ho, Heleia, Ayllon, Veronica, Real, Pedro J, Arambilet, David, Espinosa, Lluis, Torres-Ruiz, Raul, Agraz-Doblas, Antonio, Varela, Ignacio, de Boer, Jasper, Bigas, Anna, Gottgens, Bertie, Marschalek, Rolf, Menendez, Pablo
Published in Haematologica (Roma) (01.06.2019)
Published in Haematologica (Roma) (01.06.2019)
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The PARP1 selective inhibitor saruparib (AZD5305) elicits potent and durable antitumor activity in patient-derived BRCA1/2-associated cancer models
Herencia-Ropero, Andrea, Llop-Guevara, Alba, Staniszewska, Anna D, Domènech-Vivó, Joanna, García-Galea, Eduardo, Moles-Fernández, Alejandro, Pedretti, Flaminia, Domènech, Heura, Rodríguez, Olga, Guzmán, Marta, Arenas, Enrique J, Verdaguer, Helena, Calero-Nieto, Fernando J, Talbot, Sara, Tobalina, Luis, Leo, Elisabetta, Lau, Alan, Nuciforo, Paolo, Dienstmann, Rodrigo, Macarulla, Teresa, Arribas, Joaquín, Díez, Orland, Gutiérrez-Enríquez, Sara, Forment, Josep V, O'Connor, Mark J, Albertella, Mark, Balmaña, Judith, Serra, Violeta
Published in Genome medicine (26.08.2024)
Published in Genome medicine (26.08.2024)
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GATA2 Promotes Hematopoietic Development and Represses Cardiac Differentiation of Human Mesoderm
Castaño, Julio, Aranda, Sergi, Bueno, Clara, Calero-Nieto, Fernando J., Mejia-Ramirez, Eva, Mosquera, Jose Luis, Blanco, Enrique, Wang, Xiaonan, Prieto, Cristina, Zabaleta, Lorea, Mereu, Elisabetta, Rovira, Meritxell, Jiménez-Delgado, Senda, Matson, Daniel R., Heyn, Holger, Bresnick, Emery H., Göttgens, Berthold, Di Croce, Luciano, Menendez, Pablo, Raya, Angel, Giorgetti, Alessandra
Published in Stem cell reports (10.09.2019)
Published in Stem cell reports (10.09.2019)
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An experimentally validated network of nine haematopoietic transcription factors reveals mechanisms of cell state stability
Schütte, Judith, Wang, Huange, Antoniou, Stella, Jarratt, Andrew, Wilson, Nicola K, Riepsaame, Joey, Calero-Nieto, Fernando J, Moignard, Victoria, Basilico, Silvia, Kinston, Sarah J, Hannah, Rebecca L, Chan, Mun Chiang, Nürnberg, Sylvia T, Ouwehand, Willem H, Bonzanni, Nicola, de Bruijn, Marella Ftr, Göttgens, Berthold
Published in eLife (22.02.2016)
Published in eLife (22.02.2016)
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Runx1 binds as a dimeric complex to overlapping Runx1 sites within a palindromic element in the human GM-CSF enhancer
Bowers, Sarion R, Calero-Nieto, Fernando J, Valeaux, Stephanie, Fernandez-Fuentes, Narcis, Cockerill, Peter N
Published in Nucleic acids research (01.10.2010)
Published in Nucleic acids research (01.10.2010)
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The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice
Khandanpour, Cyrus, Krongold, Joseph, Schɒtte, Judith, Bouwman, Frederique, Vassen, Lothar, Gaudreau, Marie-Claude, Chen, Riyan, Calero-Nieto, Fernando J., Diamanti, Evangelia, Hannah, Rebecca, Meyer, Sara E., Grimes, H. Leighton, van der Reijden, Bert A., Jansen, Joop H., Patel, Chandrashekhar V., Peeters, Justine K., Löwenberg, Bob, Dɒhrsen, Ulrich, Göttgens, Bertie, Möröy, Tarik
Published in Blood (08.11.2012)
Published in Blood (08.11.2012)
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A single-cell molecular map of mouse gastrulation and early organogenesis
Pijuan-Sala, Blanca, Griffiths, Jonathan A., Guibentif, Carolina, Hiscock, Tom W., Jawaid, Wajid, Calero-Nieto, Fernando J., Mulas, Carla, Ibarra-Soria, Ximena, Tyser, Richard C. V., Ho, Debbie Lee Lian, Reik, Wolf, Srinivas, Shankar, Simons, Benjamin D., Nichols, Jennifer, Marioni, John C., Göttgens, Berthold
Published in Nature (London) (01.02.2019)
Published in Nature (London) (01.02.2019)
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Coagulation factor V is a T-cell inhibitor expressed by leukocytes in COVID-19
Wang, Jun, Kotagiri, Prasanti, Lyons, Paul A., Al-Lamki, Rafia S., Mescia, Federica, Bergamaschi, Laura, Turner, Lorinda, Morgan, Michael D., Calero-Nieto, Fernando J., Bach, Karsten, Mende, Nicole, Wilson, Nicola K., Watts, Emily R., Maxwell, Patrick H., Chinnery, Patrick F., Kingston, Nathalie, Papadia, Sofia, Stirrups, Kathleen E., Walker, Neil, Gupta, Ravindra K., Menon, David K., Allinson, Kieren, Aitken, Sarah J., Toshner, Mark, Weekes, Michael P., Nathan, James A., Walmsley, Sarah R., Ouwehand, Willem H., Kasanicki, Mary, Göttgens, Berthold, Marioni, John C., Smith, Kenneth G.C., Pober, Jordan S., Bradley, John R.
Published in iScience (18.03.2022)
Published in iScience (18.03.2022)
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