Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MS-STAT): a randomised, placebo-controlled, phase 2 trial
Chataway, Jeremy, Dr, Schuerer, Nadine, PhD, Alsanousi, Ali, PhD, Chan, Dennis, PhD, MacManus, David, BSc, Hunter, Kelvin, Anderson, Val, PhD, Bangham, Charles R M, Prof, Clegg, Shona, BSc, Nielsen, Casper, PhD, Fox, Nick C, Prof, Wilkie, David, MA, Nicholas, Jennifer M, PhD, Calder, Virginia L, PhD, Greenwood, John, Prof, Frost, Chris, Prof, Nicholas, Richard, PhD
Published in The Lancet (British edition) (28.06.2014)
Published in The Lancet (British edition) (28.06.2014)
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Journal Article
CD4+ T-Cell Plasticity in Non-Infectious Retinal Inflammatory Disease
Chen, Yi-Hsing, Lightman, Sue, Calder, Virginia L.
Published in International journal of molecular sciences (01.09.2021)
Published in International journal of molecular sciences (01.09.2021)
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Journal Article
Adhesion Molecule Targeted Therapy for Non-Infectious Uveitis
Chen, Yi-Hsing, Lightman, Sue, Eskandarpour, Malihe, Calder, Virginia L
Published in International journal of molecular sciences (03.01.2022)
Published in International journal of molecular sciences (03.01.2022)
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Journal Article
T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex
Hertweck, Arnulf, Evans, Catherine M., Eskandarpour, Malihe, Lau, Jonathan C.H., Oleinika, Kristine, Jackson, Ian, Kelly, Audrey, Ambrose, John, Adamson, Peter, Cousins, David J., Lavender, Paul, Calder, Virginia L., Lord, Graham M., Jenner, Richard G.
Published in Cell reports (Cambridge) (21.06.2016)
Published in Cell reports (Cambridge) (21.06.2016)
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Journal Article
Clinical Remission of Sight-Threatening Non-Infectious Uveitis Is Characterized by an Upregulation of Peripheral T-Regulatory Cell Polarized Towards T-bet and TIGIT
Gilbert, Rose M, Zhang, Xiaozhe, Sampson, Robert D, Ehrenstein, Michael R, Nguyen, Dao X, Chaudhry, Mahid, Mein, Charles, Mahmud, Nadiya, Galatowicz, Grazyna, Tomkins-Netzer, Oren, Calder, Virginia L, Lightman, Sue
Published in Frontiers in immunology (03.05.2018)
Published in Frontiers in immunology (03.05.2018)
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Journal Article
Autoantibodies contribute to the immunopathogenesis of experimental dry eye disease
Stern, Michael E, Schaumburg, Chris S, Siemasko, Karyn F, Gao, Jianping, Wheeler, Larry A, Grupe, Devin A, De Paiva, Cintia S, Calder, Virginia L, Calonge, Margarita, Niederkorn, Jerry Y, Pflugfelder, Stephen C
Published in Investigative ophthalmology & visual science (24.04.2012)
Published in Investigative ophthalmology & visual science (24.04.2012)
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Journal Article
Tear and mucus eotaxin-1 and eotaxin-2 in allergic keratoconjunctivitis
Leonardi, Andrea, Jose, Peter J, Zhan, Hong, Calder, Virginia L
Published in Ophthalmology (Rochester, Minn.) (01.03.2003)
Published in Ophthalmology (Rochester, Minn.) (01.03.2003)
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Journal Article
Cytokines and Chemokines in Uveitis – Is there a Correlation with Clinical Phenotype?
Ooi, Kenneth G-J, Galatowicz, Grazyna, Calder, Virginia L, Lightman, Susan L
Published in Clinical medicine & research (01.12.2006)
Published in Clinical medicine & research (01.12.2006)
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Journal Article
Th1- and Th2-type cytokines in chronic ocular allergy
Leonardi, Andrea, Fregona, Iva A, Plebani, Mario, Secchi, Antonio G, Calder, Virginia L
Published in Graefe's archive for clinical and experimental ophthalmology (01.10.2006)
Published in Graefe's archive for clinical and experimental ophthalmology (01.10.2006)
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Journal Article
The topical ocular delivery of rapamycin to posterior eye tissues and the suppression of retinal inflammatory disease
Badr, Moutaz Y., Halwani, Abdulrahman A., Odunze, Uchechukwu, Eskandarpour, Malihe, Calder, Virginia L., Schätzlein, Andreas G., Uchegbu, Ijeoma F.
Published in International journal of pharmaceutics (10.06.2022)
Published in International journal of pharmaceutics (10.06.2022)
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Journal Article
Functionally distinct IFN‐γ+IL‐17A+ Th cells in experimental autoimmune uveitis: T‐cell heterogeneity, migration, and steroid response
Chen, Yi‐Hsing, Eskandarpour, Malihe, Gondrand, Aurelia, Zhang, Xiaozhe, Gu, Renyang, Galatowicz, Grazyna, Lightman, Sue L., Calder, Virginia L.
Published in European journal of immunology (01.12.2020)
Published in European journal of immunology (01.12.2020)
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Journal Article
Allergic eye disease: Blocking LTB4/C5 in vivo suppressed disease and Th2 & Th9 cells
Eskandarpour, Malihe, Zhang, Xiaozhe, Micera, Alessandra, Zaher, Sarah, Larkin, Frank D. P., Nunn, Miles, Bonini, Stefano, Weston‐Davies, Wynne, Calder, Virginia L.
Published in Allergy (Copenhagen) (01.02.2022)
Published in Allergy (Copenhagen) (01.02.2022)
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Journal Article
Leukotriene B4 and Its Receptor in Experimental Autoimmune Uveitis and in Human Retinal Tissues: Clinical Severity and LTB4 Dependence of Retinal Th17 Cells
Eskandarpour, Malihe, Chen, Yi-Hsing, Nunn, Miles A, Coupland, Sarah E, Weston-Davies, Wynne, Calder, Virginia L
Published in The American journal of pathology (01.02.2021)
Published in The American journal of pathology (01.02.2021)
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Journal Article
Aldehyde dehydrogenase inhibition blocks mucosal fibrosis in human and mouse ocular scarring
Ahadome, Sarah D., Abraham, David J., Rayapureddi, Suryanarayana, Saw, Valerie P., Saban, Daniel R., Calder, Virginia L., Norman, Jill T., Ponticos, Markella, Daniels, Julie T., Dart, John K.
Published in JCI insight (04.08.2016)
Published in JCI insight (04.08.2016)
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Journal Article
The anti-inflammatory effects of therapies for ocular allergy
Mantelli, Flavio, Calder, Virginia L, Bonini, Stefano
Published in Journal of ocular pharmacology and therapeutics (01.11.2013)
Published in Journal of ocular pharmacology and therapeutics (01.11.2013)
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Journal Article
TNFα Regulates SIRT1 Cleavage during Ocular Autoimmune Disease
Gardner, Peter J, Yazid, Samia, Chu, Colin J, Copland, David A, Adamson, Peter, Dick, Andrew D, Calder, Virginia L
Published in The American journal of pathology (01.05.2015)
Published in The American journal of pathology (01.05.2015)
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Journal Article