Senicapoc: Repurposing a Drug to Target Microglia KCa3.1 in Stroke
Staal, Roland G. W., Weinstein, Jonathan R., Nattini, Megan, Cajina, Manuel, Chandresana, Gamini, Möller, Thomas
Published in Neurochemical research (01.09.2017)
Published in Neurochemical research (01.09.2017)
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Slow-release delivery enhances the pharmacological properties of oral 5-hydroxytryptophan: mouse proof-of-concept
Jacobsen, Jacob P R, Oh, Adrianna, Bangle, Rachel, Roberts, Wendy L, Royer, Elizabeth L, Modesto, Nathan, Windermere, Sonora A, Yi, Zixuan, Vernon, Rebecca, Cajina, Manuel, Urs, Nikhil M, Snyder, Joshua C, Nicholls, Peter J, Sachs, Benjamin D, Caron, Marc G
Published in Neuropsychopharmacology (New York, N.Y.) (01.11.2019)
Published in Neuropsychopharmacology (New York, N.Y.) (01.11.2019)
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Inhibition of P2X7 receptors by Lu AF27139 diminishes colonic hypersensitivity and CNS prostanoid levels in a rat model of visceral pain
Staal, Roland G. W., Gandhi, Adarsh, Zhou, Hua, Cajina, Manuel, Jacobsen, Anne-Marie, Hestehave, Sara, Hopper, Allen, Poda, Suresh, Chandresana, Gamini, Zorn, Stevin H., Campbell, Brian, Segerdahl, Marta, Mӧller, Thomas, Munro, Gordon
Published in Purinergic signalling (01.12.2022)
Published in Purinergic signalling (01.12.2022)
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S-Ketamine Mediates Its Acute and Sustained Antidepressant-Like Activity through a 5-HT1B Receptor Dependent Mechanism in a Genetic Rat Model of Depression
du Jardin, Kristian G., Liebenberg, Nico, Cajina, Manuel, Müller, Heidi K., Elfving, Betina, Sanchez, Connie, Wegener, Gregers
Published in Frontiers in pharmacology (15.01.2018)
Published in Frontiers in pharmacology (15.01.2018)
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Vortioxetine Differentially Modulates MK-801-Induced Changes in Visual Signal Detection Task Performance and Locomotor Activity
Hillhouse, Todd M, Merritt, Christina R, Smith, Douglas A, Cajina, Manuel, Sanchez, Connie, Porter, Joseph H, Pehrson, Alan L
Published in Frontiers in pharmacology (13.09.2018)
Published in Frontiers in pharmacology (13.09.2018)
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Synthesis and Characterization of the Novel Rodent-Active and CNS-Penetrant P2X7 Receptor Antagonist Lu AF27139
Hopper, Allen T, Juhl, Martin, Hornberg, Jorrit, Badolo, Lassina, Kilburn, John Paul, Thougaard, Annemette, Smagin, Gennady, Song, Dekun, Calice, Londye, Menon, Veena, Dale, Elena, Zhang, Hong, Cajina, Manuel, Nattini, Megan E, Gandhi, Adarsh, Grenon, Michel, Jones, Ken, Khayrullina, Tanzilya, Chandrasena, Gamini, Thomsen, Christian, Zorn, Stevin H, Brodbeck, Robb, Poda, Suresh Babu, Staal, Roland, Möller, Thomas
Published in Journal of medicinal chemistry (22.04.2021)
Published in Journal of medicinal chemistry (22.04.2021)
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P2X7 receptor-mediated release of microglial prostanoids and miRNAs correlates with reversal of neuropathic hypersensitivity in rats
Staal, Roland, Khayrullina, Tanzilya, Christensen, Rie, Hestehave, Sara, Zhou, Hua, Cajina, Manuel, Nattini, Megan E, Gandhi, Adarsh, Fallon, Shaun M, Schmidt, Megan, Zorn, Stevin H, Brodbeck, Robbin M, Chandrasena, Gamini, Segerdahl, Märta, Breysse, Nathalie, Hopper, Allen T, Möller, Thomas, Munro, Gordon
Published in European journal of pain (01.07.2022)
Published in European journal of pain (01.07.2022)
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Senicapoc: Repurposing a Drug to Target Microglia K^sub Ca^3.1 in Stroke
Staal, Roland G; W, Weinstein, Jonathan R, Nattini, Megan, Cajina, Manuel, Chandresana, Gamini, Möller, Thomas
Published in Neurochemical research (01.09.2017)
Published in Neurochemical research (01.09.2017)
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Synergy between l-DOPA and a novel positive allosteric modulator of metabotropic glutamate receptor 4: Implications for Parkinson's disease treatment and dyskinesia
Bennouar, Khaled-Ezaheir, Uberti, Michelle A., Melon, Christophe, Bacolod, Maria D., Jimenez, Hermogenes N., Cajina, Manuel, Kerkerian-Le Goff, Lydia, Doller, Darío, Gubellini, Paolo
Published in Neuropharmacology (01.03.2013)
Published in Neuropharmacology (01.03.2013)
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Chronic vortioxetine treatment in rodents modulates gene expression of neurodevelopmental and plasticity markers
Waller, Jessica A, Tamm, Joseph A, Abdourahman, Aicha, Pehrson, Alan L, Li, Yan, Cajina, Manuel, Sánchez, Connie
Published in European neuropsychopharmacology (01.02.2017)
Published in European neuropsychopharmacology (01.02.2017)
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Task- and Treatment Length-Dependent Effects of Vortioxetine on Scopolamine-Induced Cognitive Dysfunction and Hippocampal Extracellular Acetylcholine in Rats
Pehrson, Alan L, Hillhouse, Todd M, Haddjeri, Nasser, Rovera, Renaud, Porter, Joseph H, Mørk, Arne, Smagin, Gennady, Song, Dekun, Budac, David, Cajina, Manuel, Sanchez, Connie
Published in The Journal of pharmacology and experimental therapeutics (01.09.2016)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2016)
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Inhibition of the potassium channel KCa3.1 by senicapoc reverses tactile allodynia in rats with peripheral nerve injury
Staal, Roland G.W., Khayrullina, Tanzilya, Zhang, Hong, Davis, Scott, Fallon, Shaun M., Cajina, Manuel, Nattini, Megan E., Hu, Andrew, Zhou, Hua, Poda, Suresh Babu, Zorn, Stevin, Chandrasena, Gamini, Dale, Elena, Cambpell, Brian, Biilmann Rønn, Lars Christian, Munro, Gordon, Mӧller, Thomas
Published in European journal of pharmacology (15.01.2017)
Published in European journal of pharmacology (15.01.2017)
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The interaction of escitalopram and R-citalopram at the human serotonin transporter investigated in the mouse
Jacobsen, Jacob P. R., Plenge, Per, Sachs, Benjamin D., Pehrson, Alan L., Cajina, Manuel, Du, Yunzhi, Roberts, Wendy, Rudder, Meghan L., Dalvi, Prachiti, Robinson, Taylor J., O’Neill, Sharon P., Khoo, King S., Morillo, Connie Sanchez, Zhang, Xiaodong, Caron, Marc G.
Published in Psychopharmacology (01.12.2014)
Published in Psychopharmacology (01.12.2014)
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S -Ketamine Mediates Its Acute and Sustained Antidepressant-Like Activity through a 5-HT 1B Receptor Dependent Mechanism in a Genetic Rat Model of Depression
du Jardin, Kristian G, Liebenberg, Nico, Cajina, Manuel, Müller, Heidi K, Elfving, Betina, Sanchez, Connie, Wegener, Gregers
Published in Frontiers in pharmacology (2017)
Get full text
Published in Frontiers in pharmacology (2017)
Journal Article
Inhibition of the potassium channel K Ca 3.1 by senicapoc reverses tactile allodynia in rats with peripheral nerve injury
Staal, Roland G W, Khayrullina, Tanzilya, Zhang, Hong, Davis, Scott, Fallon, Shaun M, Cajina, Manuel, Nattini, Megan E, Hu, Andrew, Zhou, Hua, Poda, Suresh Babu, Zorn, Stevin, Chandrasena, Gamini, Dale, Elena, Cambpell, Brian, Biilmann Rønn, Lars Christian, Munro, Gordon, Mӧller, Thomas
Published in European journal of pharmacology (15.01.2017)
Published in European journal of pharmacology (15.01.2017)
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Qualification of LSP1-2111 as a Brain Penetrant Group III Metabotropic Glutamate Receptor Orthosteric Agonist
Cajina, Manuel, Nattini, Megan, Song, Dekun, Smagin, Gennady, Jørgensen, Erling B, Chandrasena, Gamini, Bundgaard, Christoffer, Toft, Dorthe Bach, Huang, Xinyan, Acher, Francine, Doller, Dario
Published in ACS medicinal chemistry letters (13.02.2014)
Published in ACS medicinal chemistry letters (13.02.2014)
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Journal Article
Senicapoc: Repurposing a Drug to Target Microglia K Ca 3.1 in Stroke
Staal, Roland G W, Weinstein, Jonathan R, Nattini, Megan, Cajina, Manuel, Chandresana, Gamini, Möller, Thomas
Published in Neurochemical research (01.09.2017)
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Published in Neurochemical research (01.09.2017)
Journal Article
4-(1-Phenyl-1H-pyrazol-4-yl)quinolines as novel, selective and brain penetrant metabotropic glutamate receptor 4 positive allosteric modulators
Jimenez, Hermogenes N., Liu, Kevin G., Hong, Sang-Phyo, Reitman, Michael S., Uberti, Michelle A., Bacolod, Maria D., Cajina, Manuel, Nattini, Megan, Sabio, Michael, Doller, Darío
Published in Bioorganic & medicinal chemistry letters (01.05.2012)
Published in Bioorganic & medicinal chemistry letters (01.05.2012)
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The MCH 1 receptor antagonist SNAP 94847 induces sensitivity to dopamine D 2/D 3 receptor agonists in rats and mice
Marsteller, Douglas A., Gerald, Christophe P.G., Kong, Ron, Cajina, Manuel, Craig, Douglas A., Swanson, Chad J.
Published in European journal of pharmacology (2009)
Published in European journal of pharmacology (2009)
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The MCH1 receptor antagonist SNAP 94847 induces sensitivity to dopamine D2/D3 receptor agonists in rats and mice
MARSTELLER, Douglas A, GERALD, Christophe P. G, RON KONG, CAJINA, Manuel, CRAIG, Douglas A, SWANSON, Chad J
Published in European journal of pharmacology (05.01.2009)
Published in European journal of pharmacology (05.01.2009)
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