Vaccine-induced antibodies to herpes simplex virus glycoprotein D epitopes involved in virus entry and cell-to-cell spread correlate with protection against genital disease in guinea pigs
Hook, Lauren M, Cairns, Tina M, Awasthi, Sita, Brooks, Benjamin D, Ditto, Noah T, Eisenberg, Roselyn J, Cohen, Gary H, Friedman, Harvey M
Published in PLoS pathogens (01.05.2018)
Published in PLoS pathogens (01.05.2018)
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Journal Article
Global sensing of the antigenic structure of herpes simplex virus gD using high-throughput array-based SPR imaging
Cairns, Tina M, Ditto, Noah T, Lou, Huan, Brooks, Benjamin D, Atanasiu, Doina, Eisenberg, Roselyn J, Cohen, Gary H
Published in PLoS pathogens (14.06.2017)
Published in PLoS pathogens (14.06.2017)
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Journal Article
Herpes virus fusion and entry: a story with many characters
Eisenberg, Roselyn J, Atanasiu, Doina, Cairns, Tina M, Gallagher, John R, Krummenacher, Claude, Cohen, Gary H
Published in Viruses (01.05.2012)
Published in Viruses (01.05.2012)
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Journal Article
Book Review
Using Split Luciferase Assay and Anti-Herpes Simplex Virus Glycoprotein Monoclonal Antibodies To Predict a Functional Binding Site between gD and gH/gL
Atanasiu, Doina, Saw, Wan Ting, Cairns, Tina M, Eisenberg, Roselyn J, Cohen, Gary H
Published in Journal of virology (25.03.2021)
Published in Journal of virology (25.03.2021)
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Journal Article
Surface Plasmon Resonance Reveals Direct Binding of Herpes Simplex Virus Glycoproteins gH/gL to gD and Locates a gH/gL Binding Site on gD
Cairns, Tina M, Ditto, Noah T, Atanasiu, Doina, Lou, Huan, Brooks, Benjamin D, Saw, Wan Ting, Eisenberg, Roselyn J, Cohen, Gary H
Published in Journal of virology (01.08.2019)
Published in Journal of virology (01.08.2019)
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Journal Article
Localization of the Interaction Site of Herpes Simplex Virus Glycoprotein D (gD) on the Membrane Fusion Regulator, gH/gL
Cairns, Tina M, Atanasiu, Doina, Saw, Wan Ting, Lou, Huan, Whitbeck, J Charles, Ditto, Noah T, Bruun, Birgitte, Browne, Helena, Bennett, Lucas, Wu, Chun, Krummenacher, Claude, Brooks, Benjamin D, Eisenberg, Roselyn J, Cohen, Gary H
Published in Journal of virology (29.09.2020)
Published in Journal of virology (29.09.2020)
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Journal Article
Receptor Binding-Induced Conformational Changes in Herpes Simplex Virus Glycoprotein D Permit Interaction with the gH/gL Complex to Activate Fusion
Atanasiu, Doina, Saw, Wan Ting, Cairns, Tina M, Friedman, Harvey M, Eisenberg, Roselyn J, Cohen, Gary H
Published in Viruses (30.03.2023)
Published in Viruses (30.03.2023)
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Journal Article
Using Antibodies and Mutants To Localize the Presumptive gH/gL Binding Site on Herpes Simplex Virus gD
Atanasiu, Doina, Saw, Wan Ting, Lazear, Eric, Whitbeck, J Charles, Cairns, Tina M, Lou, Huan, Eisenberg, Roselyn J, Cohen, Gary H
Published in Journal of virology (15.12.2018)
Published in Journal of virology (15.12.2018)
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Journal Article
Bimolecular complementation reveals that glycoproteins gB and gH/gL of herpes simplex virus interact with each other during cell fusion
Atanasiu, Doina, Whitbeck, J. Charles, Cairns, Tina M, Reilly, Brigid, Cohen, Gary H, Eisenberg, Roselyn J
Published in Proceedings of the National Academy of Sciences - PNAS (20.11.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (20.11.2007)
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Journal Article
Dissection of the antibody response against herpes simplex virus glycoproteins in naturally infected humans
Cairns, Tina M, Huang, Zhen-Yu, Whitbeck, J Charles, Ponce de Leon, Manuel, Lou, Huan, Wald, Anna, Krummenacher, Claude, Eisenberg, Roselyn J, Cohen, Gary H
Published in Journal of virology (01.11.2014)
Published in Journal of virology (01.11.2014)
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Journal Article
The Structure of Herpesvirus Fusion Glycoprotein B-Bilayer Complex Reveals the Protein-Membrane and Lateral Protein-Protein Interaction
Maurer, Ulrike E., Zeev-Ben-Mordehai, Tzviya, Pandurangan, Arun Prasad, Cairns, Tina M., Hannah, Brian P., Whitbeck, J. Charles, Eisenberg, Roselyn J., Cohen, Gary H., Topf, Maya, Huiskonen, Juha T., Grünewald, Kay
Published in Structure (London) (06.08.2013)
Published in Structure (London) (06.08.2013)
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Journal Article
Antibody responses to crucial functional epitopes as a novel approach to assess immunogenicity of vaccine adjuvants
Awasthi, Sita, Hook, Lauren M., Swaminathan, Gokul, Cairns, Tina M., Brooks, Benjamin, Smith, Jeffrey S., Ditto, Noah T., Gindy, Marian E., Bett, Andrew J., Espeseth, Amy S., Cohen, Gary H., Friedman, Harvey M.
Published in Vaccine (27.06.2019)
Published in Vaccine (27.06.2019)
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Journal Article
Characterizing Epitope Binding Regions of Entire Antibody Panels by Combining Experimental and Computational Analysis of Antibody: Antigen Binding Competition
Brooks, Benjamin D, Closmore, Adam, Yang, Juechen, Holland, Michael, Cairns, Tina, Cohen, Gary H, Bailey-Kellogg, Chris
Published in Molecules (Basel, Switzerland) (11.08.2020)
Published in Molecules (Basel, Switzerland) (11.08.2020)
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Journal Article
Mechanism of Neutralization of Herpes Simplex Virus by Antibodies Directed at the Fusion Domain of Glycoprotein B
Cairns, Tina M, Fontana, Juan, Huang, Zhen-Yu, Whitbeck, J Charles, Atanasiu, Doina, Rao, Samhita, Shelly, Spencer S, Lou, Huan, Ponce de Leon, Manuel, Steven, Alasdair C, Eisenberg, Roselyn J, Cohen, Gary H
Published in Journal of Virology (01.03.2014)
Published in Journal of Virology (01.03.2014)
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Journal Article
Antibodies to Crucial Epitopes on HSV-2 Glycoprotein D as a Guide to Dosing an mRNA Genital Herpes Vaccine
Hook, Lauren M, Awasthi, Sita, Cairns, Tina M, Alameh, Mohamad-Gabriel, Fowler, Bernard T, Egan, Kevin P, Sung, Molly M H, Weissman, Drew, Cohen, Gary H, Friedman, Harvey M
Published in Viruses (05.03.2022)
Published in Viruses (05.03.2022)
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Journal Article
Antibody-Induced Conformational Changes in Herpes Simplex Virus Glycoprotein gD Reveal New Targets for Virus Neutralization
LAZEAR, Eric, WHITBECK, J. Charles, PONCE-DE-LEON, Manuel, CAIRNS, Tina M, WILLIS, Sharon H, YI ZUO, KRUMMENACHER, Claude, COHEN, Gary H, EISENBERG, Roselyn J
Published in Journal of Virology (01.02.2012)
Published in Journal of Virology (01.02.2012)
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Journal Article
Patient-Specific Neutralizing Antibody Responses to Herpes Simplex Virus Are Attributed to Epitopes on gD, gB, or Both and Can Be Type Specific
Cairns, Tina M, Huang, Zhen-Yu, Gallagher, John R, Lin, Yixin, Lou, Huan, Whitbeck, J Charles, Wald, Anna, Cohen, Gary H, Eisenberg, Roselyn J
Published in Journal of virology (01.09.2015)
Published in Journal of virology (01.09.2015)
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Journal Article