Diverse HIV viruses are targeted by a conformationally dynamic antiviral
Caines, Matthew E C, Bichel, Katsiaryna, Price, Amanda J, McEwan, William A, Towers, Greg J, Willett, Brian J, Freund, Stefan M V, James, Leo C
Published in Nature structural & molecular biology (01.04.2012)
Published in Nature structural & molecular biology (01.04.2012)
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Journal Article
Structural Basis for T-antigen Hydrolysis by Streptococcus pneumoniae: A TARGET FOR STRUCTURE-BASED VACCINE DESIGN
Caines, Matthew E.C, Zhu, Haizhong, Vuckovic, Marija, Willis, Lisa M, Withers, Stephen G, Wakarchuk, Warren W, Strynadka, Natalie C.J
Published in The Journal of biological chemistry (14.11.2008)
Published in The Journal of biological chemistry (14.11.2008)
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Journal Article
Structural and Mechanistic Analyses of endo-Glycoceramidase II, a Membrane-associated Family 5 Glycosidase in the Apo and GM3 Ganglioside-bound Forms
Caines, Matthew E.C., Vaughan, Mark D., Tarling, Chris A., Hancock, Susan M., Warren, R. Antony J., Withers, Stephen G., Strynadka, Natalie C.J.
Published in The Journal of biological chemistry (11.05.2007)
Published in The Journal of biological chemistry (11.05.2007)
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Journal Article
The enzymology of clavam and carbapenem biosynthesis
Kershaw, Nadia J, Caines, Matthew E C, Sleeman, Mark C, Schofield, Christopher J
Published in Chemical communications (Cambridge, England) (14.09.2005)
Published in Chemical communications (Cambridge, England) (14.09.2005)
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Journal Article
Crystal Structures of an Oligopeptide-Binding Protein from the Biosynthetic Pathway of the β-Lactamase Inhibitor Clavulanic Acid
Mackenzie, Alasdair K., Valegård, Karin, Iqbal, Aman, Caines, Matthew E.C., Kershaw, Nadia J., Jensen, Susan E., Schofield, Christopher J., Andersson, Inger
Published in Journal of molecular biology (2010)
Published in Journal of molecular biology (2010)
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Journal Article
The Structural Basis of Glycosidase Inhibition by Five-Membered Iminocyclitols: The Clan A Glycoside Hydrolase Endoglycoceramidase as a Model System
Caines, Matthew E. C., Hancock, Susan M., Tarling, Chris A., Wrodnigg, Tanja M., Stick, Robert V., Stütz, Arnold E., Vasella, Andrea, Withers, Stephen G., Strynadka, Natalie C. J.
Published in Angewandte Chemie (International ed.) (01.01.2007)
Published in Angewandte Chemie (International ed.) (01.01.2007)
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Journal Article
Designer enzymes for glycosphingolipid synthesis by directed evolution
Hancock, Susan M, Rich, Jamie R, Caines, Matthew E C, Strynadka, Natalie C J, Withers, Stephen G
Published in Nature chemical biology (14.06.2009)
Published in Nature chemical biology (14.06.2009)
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Journal Article
The Structural Basis for T-antigen Hydrolysis by Streptococcus pneumoniae
Caines, Matthew E.C., Zhu, Haizhong, Vuckovic, Marija, Willis, Lisa M., Withers, Stephen G., Wakarchuk, Warren W., Strynadka, Natalie C.J.
Published in The Journal of biological chemistry (14.11.2008)
Published in The Journal of biological chemistry (14.11.2008)
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Journal Article
Crystal Structure and Mechanistic Implications of N2-(2-Carboxyethyl)arginine Synthase, the First Enzyme in the Clavulanic Acid Biosynthesis Pathway
Caines, Matthew E.C., Elkins, Jonathan M., Hewitson, Kirsty S., Schofield, Christopher J.
Published in The Journal of biological chemistry (13.02.2004)
Published in The Journal of biological chemistry (13.02.2004)
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Journal Article