Cancer exosomes induce tumor innervation
Madeo, Marianna, Colbert, Paul L., Vermeer, Daniel W., Lucido, Christopher T., Cain, Jacob T., Vichaya, Elisabeth G., Grossberg, Aaron J., Muirhead, DesiRae, Rickel, Alex P., Hong, Zhongkui, Zhao, Jing, Weimer, Jill M., Spanos, William C., Lee, John H., Dantzer, Robert, Vermeer, Paola D.
Published in Nature communications (16.10.2018)
Published in Nature communications (16.10.2018)
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Journal Article
AAV9 Gene Therapy Increases Lifespan and Treats Pathological and Behavioral Abnormalities in a Mouse Model of CLN8-Batten Disease
Johnson, Tyler B., White, Katherine A., Brudvig, Jon J., Cain, Jacob T., Langin, Logan, Pratt, Melissa A., Booth, Clarissa D., Timm, Derek J., Davis, Samantha S., Meyerink, Brandon, Likhite, Shibi, Meyer, Kathrin, Weimer, Jill M.
Published in Molecular therapy (06.01.2021)
Published in Molecular therapy (06.01.2021)
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Journal Article
A tailored mouse model of CLN2 disease: A nonsense mutant for testing personalized therapies
Geraets, Ryan D, Langin, Logan M, Cain, Jacob T, Parker, Camille M, Beraldi, Rosanna, Kovacs, Attila D, Weimer, Jill M, Pearce, David A
Published in PloS one (02.05.2017)
Published in PloS one (02.05.2017)
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Journal Article
Early postnatal administration of an AAV9 gene therapy is safe and efficacious in CLN3 disease
Johnson, Tyler B, Brudvig, Jon J, Likhite, Shibi, Pratt, Melissa A, White, Katherine A, Cain, Jacob T, Booth, Clarissa D, Timm, Derek J, Davis, Samantha S, Meyerink, Brandon, Pineda, Ricardo, Dennys-Rivers, Cassandra, Kaspar, Brian K, Meyer, Kathrin, Weimer, Jill M
Published in Frontiers in genetics (24.03.2023)
Published in Frontiers in genetics (24.03.2023)
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Journal Article
Searching for novel biomarkers using a mouse model of CLN3-Batten disease
Timm, Derek, Cain, Jacob T, Geraets, Ryan D, White, Katherine A, Koh, Seung Yon, Kielian, Tammy, Pearce, David A, Hastings, Michelle L, Weimer, Jill M
Published in PloS one (07.08.2018)
Published in PloS one (07.08.2018)
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Journal Article
Transmembrane Batten Disease Proteins Interact With a Shared Network of Vesicle Sorting Proteins, Impacting Their Synaptic Enrichment
Rechtzigel, Mitchell J, Meyerink, Brandon L, Leppert, Hannah, Johnson, Tyler B, Cain, Jacob T, Ferrandino, Gavin, May, Danielle G, Roux, Kyle J, Brudvig, Jon J, Weimer, Jill M
Published in Frontiers in neuroscience (25.05.2022)
Published in Frontiers in neuroscience (25.05.2022)
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Journal Article
Tracking sex-dependent differences in a mouse model of CLN6-Batten disease
Poppens, McKayla J, Cain, Jacob T, Johnson, Tyler B, White, Katherine A, Davis, Samantha S, Laufmann, Rachel, Kloth, Alexander D, Weimer, Jill M
Published in Orphanet journal of rare diseases (21.01.2019)
Published in Orphanet journal of rare diseases (21.01.2019)
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Journal Article
Nonsense pathogenic variants in exon 1 of PHOX2B lead to translational reinitiation in congenital central hypoventilation syndrome
Cain, Jacob T., Kim, Dae I., Quast, Megan, Shivega, Winnie G., Patrick, Ryan J., Moser, Chuanpit, Reuter, Suzanne, Perez, Myrza, Myers, Angela, Weimer, Jill M., Roux, Kyle J., Landsverk, Megan
Published in American journal of medical genetics. Part A (01.05.2017)
Published in American journal of medical genetics. Part A (01.05.2017)
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Journal Article
Modulation of CRMP2 via ( S )-Lacosamide shows therapeutic promise but is ultimately ineffective in a mouse model of CLN6-Batten disease
White, Katherine A, Cain, Jacob T, Magee, Helen, Yeon, Seul Ki, Park, Ki Duk, Khanna, Rajesh, Weimer, Jill M
Published in Health psychology & behavioral medicine (01.06.2019)
Published in Health psychology & behavioral medicine (01.06.2019)
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Journal Article
Orexin 1 Receptor Antagonism in the Basolateral Amygdala Shifts the Balance From Pro- to Antistress Signaling and Behavior
Yaeger, Jazmine D.W., Krupp, Kevin T., Jacobs, Benjamin M., Onserio, Benard O., Meyerink, Brandon L., Cain, Jacob T., Ronan, Patrick J., Renner, Kenneth J., DiLeone, Ralph J., Summers, Cliff H.
Published in Biological psychiatry (1969) (01.05.2022)
Published in Biological psychiatry (1969) (01.05.2022)
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Journal Article
Gene Therapy Corrects Brain and Behavioral Pathologies in CLN6-Batten Disease
Cain, Jacob T., Likhite, Shibi, White, Katherine A., Timm, Derek J., Davis, Samantha S., Johnson, Tyler B., Dennys-Rivers, Cassandra N., Rinaldi, Federica, Motti, Dario, Corcoran, Sarah, Morales, Pablo, Pierson, Christopher, Hughes, Stephanie M., Lee, Stella Y., Kaspar, Brian K., Meyer, Kathrin, Weimer, Jill M.
Published in Molecular therapy (02.10.2019)
Published in Molecular therapy (02.10.2019)
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Journal Article
A multimodal approach to identify clinically relevant biomarkers to comprehensively monitor disease progression in a mouse model of pediatric neurodegenerative disease
Johnson, Tyler B., Brudvig, Jon J., Lehtimäki, Kimmo K., Cain, Jacob T., White, Katherine A., Bragge, Timo, Rytkönen, Jussi, Huhtala, Tuulia, Timm, Derek, Vihma, Maria, Puoliväli, Jukka T., Poutiainen, Pekka, Nurmi, Antti, Weimer, Jill M.
Published in Progress in neurobiology (01.06.2020)
Published in Progress in neurobiology (01.06.2020)
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Journal Article
Author Correction: Characterization of a recurrent missense mutation in the forkhead DNA-binding domain of FOXP1
Johnson, Tyler B., Mechels, Keegan, Anderson, Ruthellen H., Cain, Jacob T., Sturdevant, David A., Braddock, Stephen, Pinz, Hailey, Wilson, Mark A., Landsverk, Megan, Roux, Kyle J., Weimer, Jill M.
Published in Scientific reports (15.04.2020)
Published in Scientific reports (15.04.2020)
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Journal Article
Characterization of a recurrent missense mutation in the forkhead DNA-binding domain of FOXP1
Johnson, Tyler B., Mechels, Keegan, Anderson, Ruthellen H., Cain, Jacob T., Sturdevant, David A., Braddock, Stephen, Pinz, Hailey, Wilson, Mark A., Landsverk, Megan, Roux, Kyle J., Weimer, Jill M.
Published in Scientific reports (01.11.2018)
Published in Scientific reports (01.11.2018)
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Journal Article
A porcine model of neurofibromatosis type 1 that mimics the human disease
White, Katherine A, Swier, Vicki J, Cain, Jacob T, Kohlmeyer, Jordan L, Meyerholz, David K, Tanas, Munir R, Uthoff, Johanna, Hammond, Emily, Li, Hua, Rohret, Frank A, Goeken, Adam, Chan, Chun-Hung, Leidinger, Mariah R, Umesalma, Shaikamjad, Wallace, Margaret R, Dodd, Rebecca D, Panzer, Karin, Tang, Amy H, Darbro, Benjamin W, Moutal, Aubin, Cai, Song, Li, Wennan, Bellampalli, Shreya S, Khanna, Rajesh, Rogers, Christopher S, Sieren, Jessica C, Quelle, Dawn E, Weimer, Jill M
Published in JCI insight (21.06.2018)
Published in JCI insight (21.06.2018)
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Journal Article
Age and Sex Influence Mitochondria and Cardiac Health in Offspring Exposed to Maternal Glucolipotoxicity
Louwagie, Eli J., Larsen, Tricia D., Wachal, Angela L., Gandy, Tyler C.T., Eclov, Julie A., Rideout, Todd C., Kern, Katherine A., Cain, Jacob T., Anderson, Ruthellen H., Mdaki, Kennedy S., Baack, Michelle L.
Published in iScience (20.11.2020)
Published in iScience (20.11.2020)
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Journal Article
Vascular endothelial growth factor (VEGF) isoform regulation of early forebrain development
Darland, Diane C., Cain, Jacob T., Berosik, Matthew A., Saint-Geniez, Magali, Odens, Patrick W., Schaubhut, Geoffrey J., Frisch, Sarah, Stemmer-Rachamimov, Anat, Darland, Tristan, D'Amore, Patricia A.
Published in Developmental biology (01.10.2011)
Published in Developmental biology (01.10.2011)
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Journal Article
Shifts in the vascular endothelial growth factor isoforms result in transcriptome changes correlated with early neural stem cell proliferation and differentiation in mouse forebrain
Cain, Jacob T., Berosik, Matthew A., Snyder, Stephanie D., Crawford, Natalie F., Nour, Shirin I., Schaubhut, Geoffrey J., Darland, Diane C.
Published in Developmental neurobiology (Hoboken, N.J.) (01.01.2014)
Published in Developmental neurobiology (Hoboken, N.J.) (01.01.2014)
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Journal Article
Orexin 1 Receptor Antagonism in the Basolateral Amygdala Shifts the Balance from Pro- to Anti-stress Signaling and Behavior
Yaeger, Jazmine D.W., Krupp, Kevin T., Jacobs, Benjamin M., Onserio, Benard O., Meyerink, Brandon L., Cain, Jacob T., Ronan, Patrick J., Renner, Kenneth J., DiLeone, Ralph J., Summers, Cliff H.
Published in Biological psychiatry (1969) (19.01.2022)
Published in Biological psychiatry (1969) (19.01.2022)
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Journal Article