Search Results - "Cai, Sui-Xiong" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery of 4-Aryl-4H-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-Based High Throughput Screening Assay. 4. Structure–Activity Relationships of N-Alkyl Substituted Pyrrole Fused at the 7,8-Positions

Discovery of 4-Aryl-4H-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-Based High Throughput Screening Assay. 4. Structure–Activity Relationships of N-Alkyl Substituted Pyrrole Fused at the 7,8-Positions

by Kemnitzer, William, Drewe, John, Jiang, Songchun, Zhang, Hong, Crogan-Grundy, Candace, Labreque, Denis, Bubenick, Monica, Attardo, Giorgio, Denis, Real, Lamothe, Serge, Gourdeau, Henriette, Tseng, Ben, Kasibhatla, Shailaja, Cai, Sui Xiong
Published in Journal of medicinal chemistry (14.02.2008)

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A Chemical Genetics Approach for the Discovery of Apoptosis Inducers:From Phenotypic Cell Based HTS Assay and Structure-Activity Relationship Studies, to Identification of Potential Anticancer Agents and Molecular Targets

A Chemical Genetics Approach for the Discovery of Apoptosis Inducers:From Phenotypic Cell Based HTS Assay and Structure-Activity Relationship Studies, to Identification of Potential Anticancer Agents and Molecular Targets

by SUI XIONG CAI, DREWE, John, KASIBHATLA, Shailaja
Published in Current medicinal chemistry (01.09.2006)

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Discovery of 4-Aryl-4H-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-Based High-Throughput Screening Assay. 3. Structure−Activity Relationships of Fused Rings at the 7,8-Positions

Discovery of 4-Aryl-4H-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-Based High-Throughput Screening Assay. 3. Structure−Activity Relationships of Fused Rings at the 7,8-Positions

by Kemnitzer, William, Drewe, John, Jiang, Songchun, Zhang, Hong, Zhao, Jianghong, Crogan-Grundy, Candace, Xu, Lifen, Lamothe, Serge, Gourdeau, Henriette, Denis, Réal, Tseng, Ben, Kasibhatla, Shailaja, Cai, Sui Xiong
Published in Journal of medicinal chemistry (14.06.2007)

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Antivascular and antitumor evaluation of 2-amino-4-(3-bromo-4,5-dimethoxy-phenyl)-3-cyano-4H-chromenes, a novel series of anticancer agents

Antivascular and antitumor evaluation of 2-amino-4-(3-bromo-4,5-dimethoxy-phenyl)-3-cyano-4H-chromenes, a novel series of anticancer agents

by Gourdeau, Henriette, Leblond, Lorraine, Hamelin, Bettina, Desputeau, Clemence, Dong, Kelly, Kianicka, Irenej, Custeau, Dominique, Boudreau, Chantal, Geerts, Lilianne, Cai, Sui-Xiong, Drewe, John, Labrecque, Denis, Kasibhatla, Shailaja, Tseng, Ben
Published in Molecular cancer therapeutics (01.11.2004)

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MPC-6827 : A small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps

MPC-6827 : A small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps

by KASIBHATLA, Shailaja, BAICHWAL, Vijay, PERVIN, Azra, TSENG, Ben, CARLSON, Robert O, PLEIMAN, Christopher M, SUI XIONG CAI, ROTH, Bruce, SKVORTSOVA, Ira, SKVORTSOV, Sergej, LUKAS, Peter, ENGLISH, Nicole M, SIRISOMA, Nilantha, DREWE, John
Published in Cancer research (Chicago, Ill.) (15.06.2007)

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Discovery and mechanism of action of a novel series of apoptosis inducers with potential vascular targeting activity

Discovery and mechanism of action of a novel series of apoptosis inducers with potential vascular targeting activity

by Kasibhatla, Shailaja, Gourdeau, Henriette, Meerovitch, Karen, Drewe, John, Reddy, Sanjeeva, Qiu, Ling, Zhang, Hong, Bergeron, Frederick, Bouffard, David, Yang, Quan, Herich, John, Lamothe, Serge, Cai, Sui Xiong, Tseng, Ben
Published in Molecular cancer therapeutics (01.11.2004)

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Discovery of 2-Chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine (EP128265, MPI-0441138) as a Potent Inducer of Apoptosis with High In Vivo Activity

Discovery of 2-Chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine (EP128265, MPI-0441138) as a Potent Inducer of Apoptosis with High In Vivo Activity

by Sirisoma, Nilantha, Kasibhatla, Shailaja, Pervin, Azra, Zhang, Hong, Jiang, Songchun, Willardsen, J. Adam, Anderson, Mark B, Baichwal, Vijay, Mather, Gary G, Jessing, Kevin, Hussain, Raouf, Hoang, Khanh, Pleiman, Christopher M, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Journal of medicinal chemistry (14.08.2008)

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The Caspase Selective Inhibitor EP1013 Augments Human Islet Graft Function and Longevity in Marginal Mass Islet Transplantation in Mice

The Caspase Selective Inhibitor EP1013 Augments Human Islet Graft Function and Longevity in Marginal Mass Islet Transplantation in Mice

by EMAMAULLEE, Juliet A, DAVIS, Joy, PAWLICK, Rena, TOSO, Christian, MERANI, Shaheed, CAI, Sui-Xiong, TSENG, Ben, SHAPIRO, A. M. James
Published in Diabetes (New York, N.Y.) (01.06.2008)

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Safety, Tolerability, and Pharmacokinetics of Senaparib, a Novel PARP1/2 Inhibitor, in Chinese Patients With Advanced Solid Tumors: A Phase I Trial

Safety, Tolerability, and Pharmacokinetics of Senaparib, a Novel PARP1/2 Inhibitor, in Chinese Patients With Advanced Solid Tumors: A Phase I Trial

by Cao, Junning, Guo, Hongqian, Ji, Dongmei, Shen, Weina, Zhang, Shun, Hsieh, Chih-Yi, Xiong Cai, Sui, Edward Tian, Ye, Xu, Cong, Zhang, Pin, Xu, Binghe
Published in The oncologist (Dayton, Ohio) (11.12.2023)

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A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo

A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo

by Day, Craig W, Baric, Ralph, Cai, Sui Xiong, Frieman, Matt, Kumaki, Yohichi, Morrey, John D, Smee, Donald F, Barnard, Dale L
Published in Virology (New York, N.Y.) (20.12.2009)

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Discovery of N-(4-Methoxyphenyl)-N,2-dimethylquinazolin-4-amine, a Potent Apoptosis Inducer and Efficacious Anticancer Agent with High Blood Brain Barrier Penetration

Discovery of N-(4-Methoxyphenyl)-N,2-dimethylquinazolin-4-amine, a Potent Apoptosis Inducer and Efficacious Anticancer Agent with High Blood Brain Barrier Penetration

by Sirisoma, Nilantha, Pervin, Azra, Zhang, Hong, Jiang, Songchun, Willardsen, J. Adam, Anderson, Mark B, Mather, Gary, Pleiman, Christopher M, Kasibhatla, Shailaja, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Journal of medicinal chemistry (23.04.2009)

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Discovery and Structure−Activity Relationship of 3-Aryl-5-aryl-1,2,4-oxadiazoles as a New Series of Apoptosis Inducers and Potential Anticancer Agents

Discovery and Structure−Activity Relationship of 3-Aryl-5-aryl-1,2,4-oxadiazoles as a New Series of Apoptosis Inducers and Potential Anticancer Agents

by Zhang, Han-Zhong, Kasibhatla, Shailaja, Kuemmerle, Jared, Kemnitzer, William, Ollis-Mason, Kristin, Qiu, Ling, Crogan-Grundy, Candace, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Journal of medicinal chemistry (11.08.2005)

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Discovery of 4-Aryl-4H-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-based High-Throughput Screening Assay. 1. Structure−Activity Relationships of the 4-Aryl Group

Discovery of 4-Aryl-4H-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-based High-Throughput Screening Assay. 1. Structure−Activity Relationships of the 4-Aryl Group

by Kemnitzer, William, Drewe, John, Jiang, Songchun, Zhang, Hong, Wang, Yan, Zhao, Jianghong, Jia, Shaojuan, Herich, John, Labreque, Denis, Storer, Richard, Meerovitch, Karen, Bouffard, David, Rej, Rabindra, Denis, Real, Blais, Charles, Lamothe, Serge, Attardo, Giorgio, Gourdeau, Henriette, Tseng, Ben, Kasibhatla, Shailaja, Cai, Sui Xiong
Published in Journal of medicinal chemistry (02.12.2004)

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Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay

Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay

by ZHANG, Han-Zhong, KASIBHATLA, Shailaja, YAN WANG, HERICH, John, GUASTELLA, John, BEN TSENG, DREWE, John, SUI XIONG CAI
Published in Bioorganic & medicinal chemistry (15.01.2004)

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Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 7- and 5-, 6-, 8-positions

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 7- and 5-, 6-, 8-positions

by KEMNITZER, William, KASIBHATLA, Shailaja, VAILLANCOURT, Louis, CHARRON, Sylvie, DODD, Jennifer, ATTARDO, Giorgio, LABRECQUE, Denis, LAMOTHE, Serge, GOURDEAU, Henriette, TSENG, Ben, DREWE, John, SUI XIONG CAI, SONGCHUN JIANG, HONG ZHANG, JIANGHONG ZHAO, SHAOJUAN JIA, LIFEN XU, CROGAN-GRUNDY, Candace, DENIS, Réal, BARRIAULT, Nancy
Published in Bioorganic & medicinal chemistry letters (01.11.2005)

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Discovery of 3-aryl-5-aryl-1,2,4-oxadiazoles as a new series of apoptosis inducers. 2. Identification of more aqueous soluble analogs as potential anticancer agents

Discovery of 3-aryl-5-aryl-1,2,4-oxadiazoles as a new series of apoptosis inducers. 2. Identification of more aqueous soluble analogs as potential anticancer agents

by Kemnitzer, William, Kuemmerle, Jared, Zhang, Han-Zhong, Kasibhatla, Shailaja, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry letters (01.08.2009)

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A Role for Transferrin Receptor in Triggering Apoptosis When Targeted with Gambogic Acid

A Role for Transferrin Receptor in Triggering Apoptosis When Targeted with Gambogic Acid

by Kasibhatla, Shailaja, Jessen, Katayoun A, Maliartchouk, Sergei, Wang, Jean Yu, English, Nicole M, Drewe, John, Qiu, Ling, Archer, Shannon P, Ponce, Anthony E, Sirisoma, Nilantha, Jiang, Songchun, Zhang, Han-Zhong, Gehlsen, Kurt R, Cai, Sui Xiong, Green, Douglas R, Tseng, Ben
Published in Proceedings of the National Academy of Sciences - PNAS (23.08.2005)

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Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell-and caspase-based HTS assay. Part 5: Modifications of the 2-and 3-positions

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell-and caspase-based HTS assay. Part 5: Modifications of the 2-and 3-positions

by KEMNITZER, William, SONGCHUN JIANG, GOURDEAU, Henriette, TSENG, Ben, DREWE, John, SUI XIONG CAI, YAN WANG, KASIBHATLA, Shailaja, CROGAN-GRUNDY, Candace, BUBENIK, Monica, LABRECQUE, Denis, DENIS, Real, LAMOTHE, Serge, ATTARDO, Giorgio
Published in Bioorganic & medicinal chemistry (15.01.2008)

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Discovery of 4-anilino- N-methylthieno[3,2- d]pyrimidines and 4-anilino- N-methylthieno[2,3- d]pyrimidines as potent apoptosis inducers

Discovery of 4-anilino- N-methylthieno[3,2- d]pyrimidines and 4-anilino- N-methylthieno[2,3- d]pyrimidines as potent apoptosis inducers

by Kemnitzer, William, Sirisoma, Nilantha, May, Chris, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry letters (01.07.2009)

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Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell-and caspase-based high-throughput screening assay. Part 1: Structure-activity relationships of the 1-and 3-positions

Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell-and caspase-based high-throughput screening assay. Part 1: Structure-activity relationships of the 1-and 3-positions

by KEMNITZER, William, KUEMMERLE, Jared, SONGCHUN JIANG, ZHANG, Han-Zhong, SIRISOMA, Nilantha, KASIBHATLA, Shailaja, CROGAN-GRUNDY, Candace, TSENG, Ben, DREWE, John, SUI XIONG CAI
Published in Bioorganic & medicinal chemistry letters (01.12.2008)

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