Dual knockdown of Galectin-8 and its glycosylated ligand, the activated leukocyte cell adhesion molecule (ALCAM/CD166), synergistically delays in vivo breast cancer growth
Ferragut, Fátima, Cagnoni, Alejandro J., Colombo, Lucas L., Sánchez Terrero, Clara, Wolfenstein-Todel, Carlota, Troncoso, María F., Vanzulli, Silvia I., Rabinovich, Gabriel A., Mariño, Karina V., Elola, María T.
Published in Biochimica et biophysica acta. Molecular cell research (01.08.2019)
Published in Biochimica et biophysica acta. Molecular cell research (01.08.2019)
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Journal Article
Re-wiring regulatory cell networks in immunity by galectin–glycan interactions
Blidner, Ada G., Méndez-Huergo, Santiago P., Cagnoni, Alejandro J., Rabinovich, Gabriel A.
Published in FEBS letters (14.11.2015)
Published in FEBS letters (14.11.2015)
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Journal Article
A Dynamic Interplay of Circulating Extracellular Vesicles and Galectin-1 Reprograms Viral Latency during HIV-1 Infection
Rubione, Julia, Pérez, Paula S., Czernikier, Alejandro, Duette, Gabriel A., Pereyra Gerber, Federico Pehuen, Salido, Jimena, Fabiano, Martina P., Ghiglione, Yanina, Turk, Gabriela, Laufer, Natalia, Cagnoni, Alejandro J., Pérez Sáez, Juan M., Merlo, Joaquín P., Pascuale, Carla, Stupirski, Juan C., Sued, Omar, Varas-Godoy, Manuel, Lewin, Sharon R., Mariño, Karina V., Rabinovich, Gabriel A., Ostrowski, Matías
Published in mBio (30.08.2022)
Published in mBio (30.08.2022)
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Journal Article
Efficient Synthesis of Thiolactoside Glycoclusters by Ruthenium-Catalyzed Cycloaddition Reaction of Disubstituted Alkynes on Carbohydrate Scaffolds
Cagnoni, Alejandro J., Varela, Oscar, Uhrig, María Laura, Kovensky, José
Published in European journal of organic chemistry (01.02.2013)
Published in European journal of organic chemistry (01.02.2013)
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Journal Article
Glycosylation-dependent binding of galectin-8 to activated leukocyte cell adhesion molecule (ALCAM/CD166) promotes its surface segregation on breast cancer cells
Fernández, Marisa M., Ferragut, Fátima, Cárdenas Delgado, Víctor M., Bracalente, Candelaria, Bravo, Alicia I., Cagnoni, Alejandro J., Nuñez, Myriam, Morosi, Luciano G., Quinta, Héctor R., Espelt, María V., Troncoso, María F., Wolfenstein-Todel, Carlota, Mariño, Karina V., Malchiodi, Emilio L., Rabinovich, Gabriel A., Elola, María T.
Published in Biochimica et biophysica acta (01.10.2016)
Published in Biochimica et biophysica acta (01.10.2016)
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Journal Article
Targeting galectin-driven regulatory circuits in cancer and fibrosis
Mariño, Karina V, Cagnoni, Alejandro J, Croci, Diego O, Rabinovich, Gabriel A
Published in Nature reviews. Drug discovery (01.04.2023)
Published in Nature reviews. Drug discovery (01.04.2023)
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Journal Article
Synthesis of divalent ligands of β-thio- and β-N-galactopyranosides and related lactosides and their evaluation as substrates and inhibitors of Trypanosoma cruzi trans-sialidase
Cano, María Emilia, Agusti, Rosalía, Cagnoni, Alejandro J, Tesoriero, María Florencia, Kovensky, José, Uhrig, María Laura, de Lederkremer, Rosa M
Published in Beilstein journal of organic chemistry (19.12.2014)
Published in Beilstein journal of organic chemistry (19.12.2014)
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Journal Article
Galectin-1 fosters an immunosuppressive microenvironment in colorectal cancer by reprogramming CD8 + regulatory T cells
Cagnoni, Alejandro J, Giribaldi, María Laura, Blidner, Ada G, Cutine, Anabela M, Gatto, Sabrina G, Morales, Rosa M, Salatino, Mariana, Abba, Martín C, Croci, Diego O, Mariño, Karina V, Rabinovich, Gabriel A
Published in Proceedings of the National Academy of Sciences - PNAS (25.05.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (25.05.2021)
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Journal Article
Different roles of the heterodimer architecture of galectin-4 in selective recognition of oligosaccharides and lipopolysaccharides having ABH antigens
Quintana, Jon I., Massaro, Mora, Cagnoni, Alejandro J., Nuñez-Franco, Reyes, Delgado, Sandra, Jiménez-Osés, Gonzalo, Mariño, Karina V., Rabinovich, Gabriel A., Jiménez-Barbero, Jesús, Ardá, Ana
Published in The Journal of biological chemistry (01.08.2024)
Published in The Journal of biological chemistry (01.08.2024)
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Journal Article
Synthesis of N-acetylglucosamine and N-acetylallosamine resorcinarene-based multivalent β-thio-glycoclusters: unexpected affinity of N-acetylallosamine ligands towards Wheat Germ Agglutinin
Cristófalo, Alejandro E, Cagnoni, Alejandro J, Uhrig, María Laura
Published in Organic & biomolecular chemistry (21.09.2020)
Published in Organic & biomolecular chemistry (21.09.2020)
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Journal Article
Exploring galectin interactions with human milk oligosaccharides and blood group antigens identifies BGA6 as a functional galectin-4 ligand
Cagnoni, Alejandro J., Massaro, Mora, Cutine, Anabela M., Gimeno, Ana, Pérez-Sáez, Juan M., Manselle Cocco, Montana N., Maller, Sebastián M., Di Lella, Santiago, Jiménez-Barbero, Jesús, Ardá, Ana, Rabinovich, Gabriel A., Mariño, Karina V.
Published in The Journal of biological chemistry (01.08.2024)
Published in The Journal of biological chemistry (01.08.2024)
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Journal Article
Full-length galectin-8 and separate carbohydrate recognition domains: the whole is greater than the sum of its parts?
Cagnoni, Alejandro J, Troncoso, María F, Rabinovich, Gabriel A, Mariño, Karina V, Elola, María T
Published in Biochemical Society transactions (30.06.2020)
Published in Biochemical Society transactions (30.06.2020)
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Journal Article
The sunflower jacalin Helja: biological and structural insights of its antifungal activity against Candida albicans
Del Río, Marianela V, Radicioni, Melisa B, Cutine, Anabela M, Mariño, Karina V, Mora-Montes, Héctor M, Cagnoni, Alejandro J, Regente, Mariana C
Published in Glycobiology (Oxford) (26.07.2024)
Published in Glycobiology (Oxford) (26.07.2024)
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Journal Article
The Tn antigen promotes lung tumor growth by fostering immunosuppression and angiogenesis via interaction with Macrophage Galactose-type lectin 2 (MGL2)
da Costa, Valeria, van Vliet, Sandra J., Carasi, Paula, Frigerio, Sofía, García, Pablo A., Croci, Diego O., Festari, María Florencia, Costa, Monique, Landeira, Mercedes, Rodríguez-Zraquia, Santiago A., Cagnoni, Alejandro J., Cutine, Anabela M., Rabinovich, Gabriel A., Osinaga, Eduardo, Mariño, Karina V., Freire, Teresa
Published in Cancer letters (10.10.2021)
Published in Cancer letters (10.10.2021)
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Journal Article
Selective modifications of lactose and N-acetyllactosamine with sulfate and aromatic bulky groups unveil unique structural insights in galectin-1-ligand recognition
Massaro, Mora, Cagnoni, Alejandro J., Medrano, Francisco J., Pérez-Sáez, Juan M., Abdullayev, Shuay, Belkhadem, Karima, Mariño, Karina V., Romero, Antonio, Roy, René, Rabinovich, Gabriel A.
Published in Bioorganic & medicinal chemistry (30.10.2023)
Published in Bioorganic & medicinal chemistry (30.10.2023)
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Journal Article
Circulating galectin-1 delineates response to bevacizumab in melanoma patients and reprograms endothelial cell biology
Bannoud, Nadia, Stupirski, Juan C, Cagnoni, Alejandro J, Hockl, Pablo F, Pérez Sáez, Juan M, García, P Alfredo, Mahmoud, Yamil D, Gambarte Tudela, Julián, Scheidegger, Marco A, Marshall, Andrea, Corrie, Pippa G, Middleton, Mark R, Mariño, Karina V, Girotti, M Romina, Croci, Diego O, Rabinovich, Gabriel A
Published in Proceedings of the National Academy of Sciences - PNAS (17.01.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (17.01.2023)
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Journal Article
The disulfide bond as a key motif for the construction of multivalent glycoclusters
Cano, María Emilia, Jara, Walter Emiliano, Cagnoni, Alejandro J, Brizzio, Emmanuel, Strumia, Miriam C, Repetto, Evangelina, Uhrig, María Laura
Published in New journal of chemistry (26.09.2022)
Published in New journal of chemistry (26.09.2022)
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Journal Article
Glycosylation-dependent galectin–receptor interactions promote Chlamydia trachomatis infection
Lujan, Agustin L., Croci, Diego O., Tudela, Julián A. Gambarte, Losinno, Antonella D., Cagnoni, Alejandro J., Mariño, Karina V., Damiani, María T., Rabinovich, Gabriel A.
Published in Proceedings of the National Academy of Sciences - PNAS (26.06.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (26.06.2018)
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Journal Article
Structural insights in galectin-1-glycan recognition: Relevance of the glycosidic linkage and the N-acetylation pattern of sugar moieties
Porciúncula-González, Cecilia, Cagnoni, Alejandro J., Fontana, Carolina, Mariño, Karina V., Saenz-Méndez, Patricia, Giacomini, Cecilia, Irazoqui, Gabriela
Published in Bioorganic & medicinal chemistry (15.08.2021)
Published in Bioorganic & medicinal chemistry (15.08.2021)
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Journal Article