404 Targeting PI3K somatic mutations reduces invasion and EMT in squamous cell carcinoma of the lung
Cavazzoni, A, Bonelli, M, Saccani, F, La Monica, S, Galetti, M, Caffarra, C, Cretella, D, Fumarola, C, Alfieri, R, Petronini, P.G
Published in European journal of cancer (1990) (01.11.2014)
Published in European journal of cancer (1990) (01.11.2014)
Get full text
Journal Article
692: Effect of specific PI3K/mTOR inhibitors in squamous lung cancer cells carrying PI3K alterations
Bonelli, M, Cavazzoni, A, La Monica, S, Galetti, M, Caffarra, C, Cretella, D, Saccani, F, Fumarola, C, Alfieri, R, Petronini, P.G
Published in European journal of cancer (1990) (01.07.2014)
Published in European journal of cancer (1990) (01.07.2014)
Get full text
Journal Article
The RAF/MEK clamp VS-6766 shows strong anti-tumor activity across multiple MAPK pathway alterations, with a preferential effect on KRAS G12V
Coma, S., Musteanu, M., Mira, A., Caffarra, C., Morrison, D., Ambrogio, C., Barbacid, M., Pachter, J.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
Get full text
Journal Article
Wild-type KRAS mediates growth inhibition and resistance to MEK inhibitors through dimerization with mutant KRAS in lung adenocarcinoma
Ambrogio, C., Kohler, J., Zhou, Z., Wang, H., Paranal, R., Capelletti, M., Caffarra, C., Li, S., Lv, Q., Santamaria, D., Westover, K.D., Jänne, P.A.
Published in Annals of oncology (01.09.2017)
Published in Annals of oncology (01.09.2017)
Get full text
Journal Article
P3.02-066 Wild-Type KRAS Mediates Growth Inhibition and Resistance to MEK Inhibitors through Dimerization with Mutant KRAS in Lung Adenocarcinoma
Ambrogio, C., Kohler, J., Zhou, Z., Wang, H., Paranal, R., Capelletti, M., Caffarra, C., Li, S., Lv, Q., Gondi, S., Hunter, J., Chiarle, R., Santamaría, D., Westover, K., Jänne, P.
Published in Journal of thoracic oncology (01.11.2017)
Published in Journal of thoracic oncology (01.11.2017)
Get full text
Journal Article