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The effect of potent CYP2D6 inhibition on the pharmacokinetics and safety of deutetrabenazine in healthy volunteers
Schneider, F., Stamler, D., Bradbury, M. J., Loupe, P. S., Gordon, M. F., Rabinovich-Guilatt, L.
Published in European journal of clinical pharmacology (01.01.2022)
Published in European journal of clinical pharmacology (01.01.2022)
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CYP2D6 Inhibition and Breast Cancer Recurrence in a Population-Based Study in Denmark
Lash, T. L., Cronin-Fenton, D., Ahern, T. P., Rosenberg, C. L., Lunetta, K. L., Silliman, R. A., Garne, J. P., Sorensen, H. T., Hellberg, Y., Christensen, M., Pedersen, L., Hamilton-Dutoit, S.
Published in JNCI : Journal of the National Cancer Institute (16.03.2011)
Published in JNCI : Journal of the National Cancer Institute (16.03.2011)
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The consequences of 3,4-methylenedioxymethamphetamine induced CYP2D6 inhibition in humans
O'Mathúna, Brian, Farré, Magi, Rostami-Hodjegan, Amin, Yang, Jiansong, Cuyàs, Elisabet, Torrens, Marta, Pardo, Ricardo, Abanades, Sergio, Maluf, Silvana, Tucker, Geoffrey T, de la Torre, Rafael
Published in Journal of clinical psychopharmacology (01.10.2008)
Published in Journal of clinical psychopharmacology (01.10.2008)
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CYP2D6 inhibition by selective serotonin reuptake inhibitors: analysis of achievable steady-state plasma concentrations and the effect of ultrarapid metabolism at CYP2D6
Lam, Y W Francis, Gaedigk, Andrea, Ereshefsky, Larry, Alfaro, Cara L, Simpson, Joe
Published in Pharmacotherapy (01.08.2002)
Published in Pharmacotherapy (01.08.2002)
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CYP2D6 inhibition in patients treated with sertraline
Sproule, B A, Otton, S V, Cheung, S W, Zhong, X H, Romach, M K, Sellers, E M
Published in Journal of clinical psychopharmacology (01.04.1997)
Published in Journal of clinical psychopharmacology (01.04.1997)
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Methadone inhibits CYP2D6 and UGT2B7/2B4 in vivo: a study using codeine in methadone‐ and buprenorphine‐maintained subjects
Gelston, Eloise A., Coller, Janet K., Lopatko, Olga V., James, Heather M., Schmidt, Helmut, White, Jason M., Somogyi, Andrew A.
Published in British journal of clinical pharmacology (01.05.2012)
Published in British journal of clinical pharmacology (01.05.2012)
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Inhibition of CYP2D6‐mediated tramadol O‐demethylation in methadone but not buprenorphine maintenance patients
Coller, Janet K., Michalakas, Jennifer R., James, Heather M., Farquharson, Aaron L., Colvill, Joel, White, Jason M., Somogyi, Andrew A.
Published in British journal of clinical pharmacology (01.11.2012)
Published in British journal of clinical pharmacology (01.11.2012)
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CYP2D6 inhibition by fluoxetine, paroxetine, sertraline, and venlafaxine in a crossover study: intraindividual variability and plasma concentration correlations
Alfaro, C L, Lam, Y W, Simpson, J, Ereshefsky, L
Published in Journal of clinical pharmacology (01.01.2000)
Published in Journal of clinical pharmacology (01.01.2000)
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Effect of the potent CYP2D6 inhibitor sarpogrelate on the pharmacokinetics and pharmacodynamics of metoprolol in healthy male Korean volunteers
Cho, Doo-Yeoun, Bae, Soo Hyeon, Lee, Joeng Kee, Park, Jung Bae, Kim, Yang-Weon, Lee, Sukhyang, Oh, Euichaul, Kim, Bom-Taeck, Bae, Soo Kyung
Published in Xenobiotica (01.03.2015)
Published in Xenobiotica (01.03.2015)
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Halofantrine and chloroquine inhibit CYP2D6 activity in healthy Zambians
Simooya, O. O., Sijumbil, G., Lennard, M. S., Tucker, G. T.
Published in British journal of clinical pharmacology (01.03.1998)
Published in British journal of clinical pharmacology (01.03.1998)
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The interplay between pharmacogenetics, concomitant drugs and blood levels of amitriptyline and its main metabolites
Mifsud Buhagiar, Luana, Casha, Marilyn, Grech, Anton, Serracino Inglott, Anthony, LaFerla, Godfrey
Published in Personalized medicine (01.03.2022)
Published in Personalized medicine (01.03.2022)
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Pharmacokinetic Evaluation of the CYP3A4 and CYP2D6 Drug‐Drug Interaction and CYP3A4 Induction Potential of Omecamtiv Mecarbil: Two Open‐Label Studies in Healthy Subjects
Trivedi, Ashit, Malik, Fady I., Jafarinasabian, Pegah, Zhang, Hanze, Flach, Stephen, Abbasi, Siddique, Dutta, Sandeep, Lee, Edward
Published in Clinical pharmacology in drug development (01.02.2022)
Published in Clinical pharmacology in drug development (01.02.2022)
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Drug–drug interaction study with itraconazole supplemented with physiologically based pharmacokinetic modelling to characterize the effect of CYP3A inhibitors on venglustat pharmacokinetics
Li, Li, Zhang, Yan‐Yan, Sharma, Jyoti, Cartot‐Cotton, Sylvaine, Crawford, Nigel, Macha, Sreeraj, Li, Yi, Sahi, Jasminder
Published in British journal of clinical pharmacology (01.08.2025)
Published in British journal of clinical pharmacology (01.08.2025)
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Exposure to oral oxycodone is increased by concomitant inhibition of CYP2D6 and 3A4 pathways, but not by inhibition of CYP2D6 alone
Grönlund, Juha, Saari, Teijo I., Hagelberg, Nora M., Neuvonen, Pertti J., Olkkola, Klaus T., Laine, Kari
Published in British journal of clinical pharmacology (01.07.2010)
Published in British journal of clinical pharmacology (01.07.2010)
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Differential time course of cytochrome P450 2D6 enzyme inhibition by fluoxetine, sertraline, and paroxetine in healthy volunteers
Liston, Heidi L, DeVane, C Lindsay, Boulton, David W, Risch, Samuel C, Markowitz, John S, Goldman, Juliet
Published in Journal of clinical psychopharmacology (01.04.2002)
Published in Journal of clinical psychopharmacology (01.04.2002)
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Impact of Paroxetine, a Strong CYP2D6 Inhibitor, on SPN‐812 (Viloxazine Extended‐Release) Pharmacokinetics in Healthy Adults
Wang, Zhao, Kosheleff, Alisa R., Adeojo, Lilian W., Odebo, Oyinkansola, Adewole, Toyin, Qin, Peibing, Maletic, Vladimir, Schwabe, Stefan, Nasser, Azmi
Published in Clinical pharmacology in drug development (01.11.2021)
Published in Clinical pharmacology in drug development (01.11.2021)
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Pharmacokinetic Interaction between Pyronaridine-Artesunate and Metoprolol
Morris, Carrie A., Pokorny, Rolf, Lopez-Lazaro, Luis, Miller, Robert M., Arbe-Barnes, Sarah, Duparc, Stephan, Borghini-Fuhrer, Isabelle, Shin, Jang-Sik, Fleckenstein, Lawrence
Published in Antimicrobial agents and chemotherapy (01.10.2014)
Published in Antimicrobial agents and chemotherapy (01.10.2014)
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