Discovery of Novel Dual Mechanism of Action Src Signaling and Tubulin Polymerization Inhibitors (KX2-391 and KX2-361)
Smolinski, Michael P, Bu, Yahao, Clements, James, Gelman, Irwin H, Hegab, Taher, Cutler, David L, Fang, Jane W. S, Fetterly, Gerald, Kwan, Rudolf, Barnett, Allen, Lau, Johnson Y. N, Hangauer, David G
Published in Journal of medicinal chemistry (14.06.2018)
Published in Journal of medicinal chemistry (14.06.2018)
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Pharmacodynamics and pharmacokinetics of the novel PAR-1 antagonist vorapaxar (formerly SCH 530348) in healthy subjects
Kosoglou, Teddy, Reyderman, Larisa, Tiessen, Renger G., van Vliet, André A., Fales, Robert R., Keller, Robert, Yang, Bo, Cutler, David L.
Published in European journal of clinical pharmacology (01.03.2012)
Published in European journal of clinical pharmacology (01.03.2012)
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Journal Article
Contact Sensitization and Phototoxic and Photoallergic Potential of Tirbanibulin 1% Ointment in Healthy Volunteers
Dosik, Jonathan, Cutler, David L., Fang, Jane, Padullés, Laura
Published in JID innovations (01.03.2023)
Published in JID innovations (01.03.2023)
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Oral paclitaxel and encequidar in patients with breast cancer: a pharmacokinetic, safety, and antitumor activity study
Dai, Ming-Shen, Chao, Ta-Chung, Chiu, Chang-Fang, Lu, Yen-Shen, Shiah, Her-Shyong, Jackson, Christopher G. C. A., Hung, Noelyn, Zhi, Jianguo, Cutler, David L., Kwan, Rudolf, Kramer, Douglas, Chan, Wing-Kai, Qin, Albert, Tseng, Kuan-Chiao, Hung, Cheung Tak, Chao, Tsu-Yi
Published in Therapeutic advances in medical oncology (01.01.2023)
Published in Therapeutic advances in medical oncology (01.01.2023)
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Topical Tirbanibulin, a Dual Src Kinase and Tubulin Polymerization Inhibitor, for the Treatment of Plaque-Type Psoriasis: Phase I Results
Hong, Jin-Bon, Wu, Po-Yuan, Qin, Albert, Huang, Yi-Wen, Tseng, Kuan-Chiao, Lai, Ching-Yu, Chan, Wing-Kai, Fang, Jane, Cutler, David L, Tsai, Tsen-Fang
Published in Pharmaceutics (01.10.2022)
Published in Pharmaceutics (01.10.2022)
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Hypothalamic-pituitary-adrenal axis effects of mometasone furoate/formoterol fumarate vs fluticasone propionate/salmeterol administered through metered-dose inhaler
Kosoglou, Teddy, Hubbell, James, Cutler, David L, Johnson-Levonas, Amy O, Xu, Danlin, Kantesaria, Bhavna S, Kim, Kenneth, Miller, S David
Published in Chest (01.12.2013)
Published in Chest (01.12.2013)
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Phase 3 Trials of Tirbanibulin Ointment for Actinic Keratosis
Blauvelt, Andrew, Kempers, Steven, Lain, Edward, Schlesinger, Todd, Tyring, Stephen, Forman, Seth, Ablon, Glynis, Martin, George, Wang, Hui, Cutler, David L, Fang, Jane, Kwan, Min-Fun R
Published in The New England journal of medicine (11.02.2021)
Published in The New England journal of medicine (11.02.2021)
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Journal Article
Overview of the Clinical Pharmacology of Ertugliflozin, a Novel Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor
Fediuk, Daryl J., Nucci, Gianluca, Dawra, Vikas Kumar, Cutler, David L., Amin, Neeta B., Terra, Steven G., Boyd, Rebecca A., Krishna, Rajesh, Sahasrabudhe, Vaishali
Published in Clinical pharmacokinetics (01.08.2020)
Published in Clinical pharmacokinetics (01.08.2020)
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Journal Article
Reply to Z.R. McCaw et al
Rugo, Hope S, Umanzor, Gerardo A, Kwan, Min-Fun R, Cutler, David L
Published in Journal of clinical oncology (20.02.2023)
Published in Journal of clinical oncology (20.02.2023)
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Pharmacokinetics of Single-dose Ertugliflozin in Patients With Hepatic Impairment
Sahasrabudhe, Vaishali, Terra, Steven G., Hickman, Anne, Saur, Didier, Raje, Sangeeta, Shi, Haihong, Matschke, Kyle, Zhou, Susan, Cutler, David L.
Published in Clinical therapeutics (01.10.2018)
Published in Clinical therapeutics (01.10.2018)
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Journal Article
Open-Label, Randomized, Multicenter, Phase III Study Comparing Oral Paclitaxel Plus Encequidar Versus Intravenous Paclitaxel in Patients With Metastatic Breast Cancer
Rugo, Hope S, Umanzor, Gerardo A, Barrios, Francisco J, Vasallo, Rosa H, Chivalan, Marco A, Bejarano, Suyapa, Ramírez, Julio R, Fein, Luis, Kowalyszyn, Ruben D, Kramer, E Douglas, Wang, Hui, Kwan, Min-Fun R, Cutler, David L
Published in Journal of clinical oncology (01.01.2023)
Published in Journal of clinical oncology (01.01.2023)
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Phase I and Pharmacokinetic Study of the Oral Farnesyl Transferase Inhibitor SCH 66336 Given Twice Daily to Patients With Advanced Solid Tumors
ESKENS, Ferry A. L. M, AWADA, Ahmad, PICCART, Martine, CUTLER, David L, DE JONGE, Maja J. A, LUYTEN, Gré P. M, FABER, Marije N, STATKEVICH, Paul, SPARREBOOM, Alex, VERWEIJ, Jaap, HANAUSKE, Axel-R
Published in Journal of clinical oncology (15.02.2001)
Published in Journal of clinical oncology (15.02.2001)
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Oral paclitaxel with encequidar compared to intravenous paclitaxel in patients with advanced cancer: A randomised crossover pharmacokinetic study
Jackson, Christopher G. C. A., Hung, Tak, Segelov, Eva, Barlow, Paula, Prenen, Hans, McLaren, Blair, Hung, Noelyn Anne, Clarke, Katriona, Chao, Tsu‐Yi, Dai, Ming‐Shen, Yeh, Hsien‐Tang, Cutler, David L., Kramer, Douglas, He, Jimmy, Zhi, Jay, Chan, Wing‐Kai, Kwan, Rudolf, Deva, Sanjeev
Published in British journal of clinical pharmacology (01.12.2021)
Published in British journal of clinical pharmacology (01.12.2021)
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Effect of Rifampin on the Pharmacokinetics of Ertugliflozin in Healthy Subjects
Dawra, Vikas K., Sahasrabudhe, Vaishali, Liang, Yali, Matschke, Kyle, Shi, Haihong, Hickman, Anne, Saur, Didier, Terra, Steven G., Cutler, David L.
Published in Clinical therapeutics (01.09.2018)
Published in Clinical therapeutics (01.09.2018)
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Journal Article
Pegylated IFNs for chronic hepatitis C: an update
Grace, Michael J, Cutler, David L, Bordens, Ronald W
Published in Expert opinion on drug delivery (01.03.2005)
Published in Expert opinion on drug delivery (01.03.2005)
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Novel Application of the Two‐Period Microtracer Approach to Determine Absolute Oral Bioavailability and Fraction Absorbed of Ertugliflozin
Raje, Sangeeta, Callegari, Ernesto, Sahasrabudhe, Vaishali, Vaz, Alfin, Shi, Haihong, Fluhler, Eric, Woolf, Eric J., Schildknegt, Klaas, Matschke, Kyle, Alvey, Christine, Zhou, Susan, Papadopoulos, Dimitris, Fountaine, Robert, Saur, Didier, Terra, Steven G., Stevens, Lloyd, Gaunt, Daniel, Cutler, David L.
Published in Clinical and translational science (01.07.2018)
Published in Clinical and translational science (01.07.2018)
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Journal Article
Assessment of the Drug Interaction Potential of Ertugliflozin With Sitagliptin, Metformin, Glimepiride, or Simvastatin in Healthy Subjects
Dawra, Vikas Kumar, Cutler, David L., Zhou, Susan, Krishna, Rajesh, Shi, Haihong, Liang, Yali, Alvey, Christine, Hickman, Anne, Saur, Didier, Terra, Steven G., Sahasrabudhe, Vaishali
Published in Clinical pharmacology in drug development (01.04.2019)
Published in Clinical pharmacology in drug development (01.04.2019)
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A Phase 1, Randomized, Placebo‐ and Active‐Controlled Crossover Study to Determine the Effect of Single‐Dose Ertugliflozin on QTc Interval in Healthy Volunteers
Sahasrabudhe, Vaishali, Saur, Didier, Matschke, Kyle, Terra, Steven G., Hickman, Anne, Huyghe, Isabelle, Shi, Haihong, Cutler, David L.
Published in Clinical pharmacology in drug development (01.06.2018)
Published in Clinical pharmacology in drug development (01.06.2018)
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Journal Article
Emerging areas of research in the assessment of pharmacokinetics in patients with chronic kidney disease
Tortorici, Michael A, Cutler, David L, Hazra, Anasuya, Nolin, Thomas D, Rowland-Yeo, Karen, Venkatakrishnan, Karthik
Published in Journal of clinical pharmacology (01.03.2015)
Published in Journal of clinical pharmacology (01.03.2015)
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