TH1902, a new docetaxel‐peptide conjugate for the treatment of sortilin‐positive triple‐negative breast cancer
Demeule, Michel, Charfi, Cyndia, Currie, Jean‐Christophe, Larocque, Alain, Zgheib, Alain, Kozelko, Sophie, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane
Published in Cancer science (01.10.2021)
Published in Cancer science (01.10.2021)
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Involvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector Angiopep-2
Demeule, Michel, Currie, Jean-Christophe, Bertrand, Yanick, Ché, Christian, Nguyen, Tran, Régina, Anthony, Gabathuler, Reinhard, Castaigne, Jean-Paul, Béliveau, Richard
Published in Journal of neurochemistry (01.08.2008)
Published in Journal of neurochemistry (01.08.2008)
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Journal Article
ANG4043, a novel brain-penetrant peptide-mAb conjugate, is efficacious against HER2-positive intracranial tumors in mice
Regina, Anthony, Demeule, Michel, Tripathy, Sasmita, Lord-Dufour, Simon, Currie, Jean-Christophe, Iddir, Mustapha, Annabi, Borhane, Castaigne, Jean-Paul, Lachowicz, Jean E
Published in Molecular cancer therapeutics (01.01.2015)
Published in Molecular cancer therapeutics (01.01.2015)
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Journal Article
Sudocetaxel Zendusortide (TH1902) triggers the cGAS/STING pathway and potentiates anti-PD-L1 immune-mediated tumor cell killing
Demeule, Michel, Currie, Jean-Christophe, Charfi, Cyndia, Zgheib, Alain, Cousineau, Isabelle, Lullier, Véronique, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane
Published in Frontiers in immunology (16.02.2024)
Published in Frontiers in immunology (16.02.2024)
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New Peptide-Drug Conjugates for Precise Targeting of SORT1-Mediated Vasculogenic Mimicry in the Tumor Microenvironment of TNBC-Derived MDA-MB-231 Breast and Ovarian ES-2 Clear Cell Carcinoma Cells
Charfi, Cyndia, Demeule, Michel, Currie, Jean-Christophe, Larocque, Alain, Zgheib, Alain, Danalache, Bogdan Alexandru, Ouanouki, Amira, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane
Published in Frontiers in oncology (22.10.2021)
Published in Frontiers in oncology (22.10.2021)
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Journal Article
The Peptide-Drug Conjugate TH1902: A New Sortilin Receptor-Mediated Cancer Therapeutic against Ovarian and Endometrial Cancers
Currie, Jean-Christophe, Demeule, Michel, Charfi, Cyndia, Zgheib, Alain, Larocque, Alain, Danalache, Bogdan Alexandru, Ouanouki, Amira, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane
Published in Cancers (08.04.2022)
Published in Cancers (08.04.2022)
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Transport characteristics of a novel peptide platform for CNS therapeutics
Bertrand, Yanick, Currie, Jean‐Christophe, Demeule, Michel, Régina, Anthony, Ché, Christian, Abulrob, Abedelnasser, Fatehi, Dorothy, Sartelet, Hervé, Gabathuler, Reinhard, Castaigne, Jean‐Paul, Stanimirovic, Danica, Béliveau, Richard
Published in Journal of cellular and molecular medicine (01.12.2010)
Published in Journal of cellular and molecular medicine (01.12.2010)
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The chemopreventive properties of chlorogenic acid reveal a potential new role for the microsomal glucose-6-phosphate translocase in brain tumor progression
Belkaid, Anissa, Currie, Jean-Christophe, Desgagnés, Julie, Annabi, Borhane
Published in Cancer cell international (27.03.2006)
Published in Cancer cell international (27.03.2006)
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Journal Article
Corrigendum: Sudocetaxel Zendusortide (TH1902) triggers the cGAS/STING pathway and potentiates anti-PD-L1 immune-mediated tumor cell killing
Demeule, Michel, Currie, Jean-Christophe, Charfi, Cyndia, Zgheib, Alain, Cousineau, Isabelle, Lullier, Véronique, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane
Published in Frontiers in immunology (28.02.2024)
Published in Frontiers in immunology (28.02.2024)
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Journal Article
The TH1902 Docetaxel Peptide-Drug Conjugate Inhibits Xenografts Growth of Human SORT1-Positive Ovarian and Triple-Negative Breast Cancer Stem-like Cells
Demeule, Michel, Charfi, Cyndia, Currie, Jean-Christophe, Zgheib, Alain, Danalache, Bogdan Alexandru, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane
Published in Pharmaceutics (01.09.2022)
Published in Pharmaceutics (01.09.2022)
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Journal Article
New Angiopep-Modified Doxorubicin (ANG1007) and Etoposide (ANG1009) Chemotherapeutics With Increased Brain Penetration
Ché, Christian, Yang, Gaoqiang, Thiot, Carine, Lacoste, Marie-Claude, Currie, Jean-Christophe, Demeule, Michel, Régina, Anthony, Béliveau, Richard, Castaigne, Jean-Paul
Published in Journal of medicinal chemistry (08.04.2010)
Published in Journal of medicinal chemistry (08.04.2010)
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MT1-MMP Down-regulates the Glucose 6-Phosphate Transporter Expression in Marrow Stromal Cells: A MOLECULAR LINK BETWEEN PRO-MMP-2 ACTIVATION, CHEMOTAXIS, AND CELL SURVIVAL
Currie, Jean-Christophe, Fortier, Simon, Sina, Asmaa, Galipeau, Jacques, Cao, Jian, Annabi, Borhane
Published in The Journal of biological chemistry (16.03.2007)
Published in The Journal of biological chemistry (16.03.2007)
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Journal Article
소틸린 결합 접합체 화합물, 조성물 및 암을 치료하기 위한 이들의 용도
MARSOLAIS CHRISTIAN, DEMEULE MICHEL, CURRIE JEAN CHRISTOPHE, LAROCQUE ALAIN
Year of Publication 17.08.2022
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Year of Publication 17.08.2022
Patent
암 줄기 세포를 표적화하기 위한 방법 및 소르틸린 결합 접합체 화합물
ANNABI BORHANE, MARSOLAIS CHRISTIAN, DEMEULE MICHEL, CURRIE JEAN CHRISTOPHE, LAROCQUE ALAIN, CHARFI CYNDIA, ZGHEIB ALAIN, BELIVEAU RICHARD
Year of Publication 07.12.2023
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Year of Publication 07.12.2023
Patent
Contribution of the 37-kDa laminin receptor precursor in the anti-metastatic PSP94-derived peptide PCK3145 cell surface binding
Annabi, Borhane, Currie, Jean-Christophe, Bouzeghrane, Mounia, Dulude, Hélène, Daigneault, Luc, Garde, Seema, Rabbani, Shafaat A., Panchal, Chandra, Wu, Jinzi J., Béliveau, Richard
Published in Biochemical and biophysical research communications (21.07.2006)
Published in Biochemical and biophysical research communications (21.07.2006)
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A PSP94-derived peptide PCK3145 inhibits MMP-9 secretion and triggers CD44 cell surface shedding: implication in tumor metastasis
Annabi, Borhane, Bouzeghrane, Mounia, Currie, Jean-Christophe, Hawkins, Robert, Dulude, Hélène, Daigneault, Luc, Ruiz, Marcia, Wisniewski, Jan, Garde, Seema, Rabbani, Shafaat A, Panchal, Chandra, Wu, Jinzi J, Béliveau, Richard
Published in Clinical & experimental metastasis (01.09.2005)
Published in Clinical & experimental metastasis (01.09.2005)
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Journal Article
Inhibition of MMP-9 secretion by the anti-metastatic PSP94-derived peptide PCK3145 requires cell surface laminin receptor signaling
Annabi, Borhane, Bouzeghrane, Mounia, Currie, Jean-Christophe, Dulude, Hélène, Daigneault, Luc, Garde, Seema, Rabbani, Shafaat A, Panchal, Chandra, Wu, Jinzi J, Béliveau, Richard
Published in Anti-cancer drugs (01.04.2006)
Published in Anti-cancer drugs (01.04.2006)
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Journal Article
Abstract 6362: TH1901, a novel curcumin-peptide conjugate for the treatment of Sortilin-positive (SORT1+) cancer
Annabi, Borhane, Demeule, Michel, Currie, Jean-Christophe, Larocque, Alain, Zgheib, Alain, Marsolais, Christian, Béliveau, Richard
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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