Prolonged Scar-in-a-Jar: an in vitro screening tool for anti-fibrotic therapies using biomarkers of extracellular matrix synthesis
Rønnow, Sarah Rank, Dabbagh, Rand Qais, Genovese, Federica, Nanthakumar, Carmel B, Barrett, Vikki J, Good, Robert B, Brockbank, Sarah, Cruwys, Simon, Jessen, Henrik, Sorensen, Grith Lykke, Karsdal, Morten Asser, Leeming, Diana Julie, Sand, Jannie Marie Bülow
Published in Respiratory research (07.05.2020)
Published in Respiratory research (07.05.2020)
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Journal Article
Biochemical and histological characterisation of an experimental rodent model of non-alcoholic steatohepatitis – Effects of a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist and a glucagon-like peptide-1 analogue
Daniels, Samuel J., Leeming, Diana J., Detlefsen, Sönke, Bruun, Maria F., Hjuler, Sara T., Henriksen, Kim, Hein, Peter, Karsdal, Morten A., Brockbank, Sarah, Cruwys, Simon
Published in Biomedicine & pharmacotherapy (01.03.2019)
Published in Biomedicine & pharmacotherapy (01.03.2019)
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Journal Article
Enhancement of Angiogenesis by Endogenous Substance P Release and Neurokinin-1 Receptors During Neurogenic Inflammation
Seegers, Hélène C, Hood, Vivienne C, Kidd, Bruce L, Cruwys, Simon C, Walsh, David A
Published in The Journal of pharmacology and experimental therapeutics (01.07.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2003)
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Journal Article
Engineering an in-vitro model of rodent cartilage
Rogers, Catherine M, Woolley, Terry S, Cruwys, Simon C, Buttery, Lee D K, Rose, Felicity R A J, Shakesheff, Kevin M
Published in Journal of pharmacy and pharmacology (01.06.2012)
Published in Journal of pharmacy and pharmacology (01.06.2012)
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Journal Article
Drug discovery and development in idiopathic pulmonary fibrosis: challenges and opportunities
Cruwys, Simon, Hein, Peter, Humphries, Bob, Black, Darcey
Published in Drug discovery today (01.12.2020)
Published in Drug discovery today (01.12.2020)
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Journal Article
Inhibition of inflammation and hyperalgesia in NK-1 receptor knock-out mice
Kidd, Bruce L, Inglis, Julia J, Vetsika, Kelly, Hood, Vivienne C, De Felipe, Carmen, Bester, Herve, Hunt, Stephen P, Cruwys, Simon C
Published in Neuroreport (02.12.2003)
Published in Neuroreport (02.12.2003)
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Journal Article
The future R&D landscape in non-alcoholic steatohepatitis (NASH)
Black, Darcey, Brockbank, Sarah, Cruwys, Simon, Goldenstein, Kim, Hein, Peter, Humphries, Bob
Published in Drug discovery today (01.02.2019)
Published in Drug discovery today (01.02.2019)
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Journal Article
Mapping pathogenesis of arthritis through small animal models
VINCENT, Tonia L, WILLIAMS, Richard O, MACIEWICZ, Rose, SILMAN, Alan, GARSIDE, Paul
Published in Rheumatology (Oxford, England) (01.11.2012)
Published in Rheumatology (Oxford, England) (01.11.2012)
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Journal Article
Tissue turnover of collagen type I, III and elastin is elevated in the PCLS model of IPF and can be restored back to vehicle levels using a phosphodiesterase inhibitor
Hansen, Niels Ulrik Brandt, Karsdal, Morten Asser, Brockbank, Sarah, Cruwys, Simon, Rønnow, Sarah, Leeming, Diana Julie
Published in Respiratory research (05.07.2016)
Published in Respiratory research (05.07.2016)
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Journal Article
Addition of trans fat and alcohol has divergent effects on atherogenic diet-induced liver injury in rodent models of steatohepatitis
Daniels, Samuel J, Leeming, Diana J, Detlefsen, Sönke, Bruun, Maria F, Hjuler, Sara T, Henriksen, Kim, Hein, Peter, Krag, Aleksander, Karsdal, Morten A, Nielsen, Mette Juul, Brockbank, Sarah, Cruwys, Simon
Published in American journal of physiology: Gastrointestinal and liver physiology (01.03.2020)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.03.2020)
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Journal Article
Whole-Molecule Antibody Engineering: Generation of a High-Affinity Anti-IL-6 Antibody with Extended Pharmacokinetics
Finch, Donna K., Sleeman, Matthew A., Moisan, Jacques, Ferraro, Franco, Botterell, Sara, Campbell, Jamie, Cochrane, Duncan, Cruwys, Simon, England, Elizabeth, Lane, Steven, Rendall, Elizabeth, Sinha, Monisha, Walker, Craig, Rees, Gareth, Bowen, Michael A., Schneider, Amy, Liang, Meina, Faggioni, Raffaella, Fung, Michael, Mallinder, Philip R., Wilkinson, Trevor, Kolbeck, Roland, Vaughan, Tristan, Lowe, David C.
Published in Journal of molecular biology (26.08.2011)
Published in Journal of molecular biology (26.08.2011)
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Journal Article
추가로 치환된 트리아졸로 퀴녹살린 유도체
KLESS ACHIM, JAKOB FLORIAN, LUCAS SIMON, CRAAN TOBIAS, WACHTEN SEBASTIAN, SCHUNK STEFAN, KONETZKI INGO, ALEN JO, CRUWYS SIMON, RATCLIFFE PAUL
Year of Publication 30.03.2021
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Year of Publication 30.03.2021
Patent
BINDING MEMBERS AGAINST IL-1R1
LOWE DAVID CHRISTOPHER, CAMPBELL JAMIE IAIN, COCHRANE DUNCAN JAMES, CRUWYS SIMON CHARLES, FINCH DONNA KIRSTY, GROVES MARIA ANASTASIA TERESA
Year of Publication 18.07.2011
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Year of Publication 18.07.2011
Patent