RNase H2-Initiated Ribonucleotide Excision Repair
Sparks, Justin L., Chon, Hyongi, Cerritelli, Susana M., Kunkel, Thomas A., Johansson, Erik, Crouch, Robert J., Burgers, Peter M.
Published in Molecular cell (28.09.2012)
Published in Molecular cell (28.09.2012)
Get full text
Journal Article
The Balancing Act of Ribonucleotides in DNA
Cerritelli, Susana M., Crouch, Robert J.
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.05.2016)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.05.2016)
Get full text
Journal Article
RNase H2 catalytic core Aicardi-Goutières syndrome-related mutant invokes cGAS-STING innate immune-sensing pathway in mice
Pokatayev, Vladislav, Hasin, Naushaba, Chon, Hyongi, Cerritelli, Susana M, Sakhuja, Kiran, Ward, Jerrold M, Morris, H Douglas, Yan, Nan, Crouch, Robert J
Published in The Journal of experimental medicine (07.03.2016)
Published in The Journal of experimental medicine (07.03.2016)
Get full text
Journal Article
Primer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication
Holmes, J. Bradley, Gokhan Akman, Stuart R. Wood, Kiran Sakhuja, Susana M. Cerritelli, Chloe Moss, Mark R. Bowmaker, Howard T. Jacobs, Robert J. Crouch, Ian J. Holt
Published in Proceedings of the National Academy of Sciences - PNAS (28.07.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (28.07.2015)
Get full text
Journal Article
Characterization of six recombinant human RNase H2 bearing Aicardi-Goutiéres syndrome causing mutations
Nishimura, Takuto, Baba, Misato, Ogawa, Saori, Kojima, Kenji, Takita, Teisuke, Crouch, Robert J, Yasukawa, Kiyoshi
Published in Journal of biochemistry (Tokyo) (01.12.2019)
Published in Journal of biochemistry (Tokyo) (01.12.2019)
Get full text
Journal Article
Val143 of human ribonuclease H2 is not critical for, but plays a role in determining catalytic activity and substrate specificity
Baba, Misato, Kojima, Kenji, Nishimura, Takuto, Sugiura, Takuya, Takita, Teisuke, Uehara, Ryo, Crouch, Robert J, Yasukawa, Kiyoshi
Published in PloS one (18.02.2020)
Published in PloS one (18.02.2020)
Get full text
Journal Article
Pathological ribonuclease H1 causes R-loop depletion and aberrant DNA segregation in mitochondria
Akman, Gokhan, Desai, Radha, Bailey, Laura J., Yasukawa, Takehiro, Rosa, Ilaria Dalla, Durigon, Romina, Holmes, J. Bradley, Moss, Chloe F., Mennuni, Mara, Houlden, Henry, Crouch, Robert J., Hanna, Michael G., Pitceathly, Robert D. S., Spinazzola, Antonella, Holt, Ian J.
Published in Proceedings of the National Academy of Sciences - PNAS (26.07.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (26.07.2016)
Get full text
Journal Article
The Structural and Biochemical Characterization of Human RNase H2 Complex Reveals the Molecular Basis for Substrate Recognition and Aicardi-Goutières Syndrome Defects
Figiel, Małgorzata, Chon, Hyongi, Cerritelli, Susana M., Cybulska, Magdalena, Crouch, Robert J., Nowotny, Marcin
Published in The Journal of biological chemistry (25.03.2011)
Published in The Journal of biological chemistry (25.03.2011)
Get full text
Journal Article
Aicardi-Goutières syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer
Deasy, Sarah K, Uehara, Ryo, Vodnala, Suman K, Yang, Howard H, Dass, Randall A, Hu, Ying, Lee, Maxwell P, Crouch, Robert J, Hunter, Kent W
Published in PLoS genetics (01.05.2019)
Published in PLoS genetics (01.05.2019)
Get full text
Journal Article
An Upstream Open Reading Frame and the Context of the Two AUG Codons Affect the Abundance of Mitochondrial and Nuclear RNase H1
Suzuki, Yutaka, Holmes, J. Bradley, Cerritelli, Susana M., Sakhuja, Kiran, Minczuk, Michal, Holt, Ian J., Crouch, Robert J.
Published in Molecular and Cellular Biology (01.11.2010)
Published in Molecular and Cellular Biology (01.11.2010)
Get full text
Journal Article
Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex
Chon, Hyongi, Vassilev, Alex, DePamphilis, Melvin L, Zhao, Yingming, Zhang, Junmei, Burgers, Peter M, Crouch, Robert J, Cerritelli, Susana M
Published in Nucleic acids research (01.01.2009)
Published in Nucleic acids research (01.01.2009)
Get full text
Journal Article
Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD
Nowotny, Marcin, Cerritelli, Susana M, Ghirlando, Rodolfo, Gaidamakov, Sergei A, Crouch, Robert J, Yang, Wei
Published in The EMBO journal (09.04.2008)
Published in The EMBO journal (09.04.2008)
Get full text
Journal Article
Mammalian Mitochondrial DNA Replication Intermediates Are Essentially Duplex but Contain Extensive Tracts of RNA/DNA Hybrid
Pohjoismäki, Jaakko L.O., Holmes, J. Bradley, Wood, Stuart R., Yang, Ming-Yao, Yasukawa, Takehiro, Reyes, Aurelio, Bailey, Laura J., Cluett, Tricia J., Goffart, Steffi, Willcox, Smaranda, Rigby, Rachel E., Jackson, Andrew P., Spelbrink, Johannes N., Griffith, Jack D., Crouch, Robert J., Jacobs, Howard T., Holt, Ian J.
Published in Journal of molecular biology (16.04.2010)
Published in Journal of molecular biology (16.04.2010)
Get full text
Journal Article
Failure to Produce Mitochondrial DNA Results in Embryonic Lethality in Rnaseh1 Null Mice
Cerritelli, Susana M., Frolova, Ella G., Feng, Chiguang, Grinberg, Alexander, Love, Paul E., Crouch, Robert J.
Published in Molecular cell (01.03.2003)
Published in Molecular cell (01.03.2003)
Get full text
Journal Article
RNase H2 roles in genome integrity revealed by unlinking its activities
Chon, Hyongi, Sparks, Justin L., Rychlik, Monika, Nowotny, Marcin, Burgers, Peter M., Crouch, Robert J., Cerritelli, Susana M.
Published in Nucleic acids research (01.03.2013)
Published in Nucleic acids research (01.03.2013)
Get full text
Journal Article