Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
Shimada, Kenichi, Crother, Timothy R., Karlin, Justin, Dagvadorj, Jargalsaikhan, Chiba, Norika, Chen, Shuang, Ramanujan, V. Krishnan, Wolf, Andrea J., Vergnes, Laurent, Ojcius, David M., Rentsendorj, Altan, Vargas, Mario, Guerrero, Candace, Wang, Yinsheng, Fitzgerald, Katherine A., Underhill, David M., Town, Terrence, Arditi, Moshe
Published in Immunity (Cambridge, Mass.) (23.03.2012)
Published in Immunity (Cambridge, Mass.) (23.03.2012)
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Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation
Xian, Hongxu, Liu, Yuan, Rundberg Nilsson, Alexandra, Gatchalian, Raphaella, Crother, Timothy R., Tourtellotte, Warren G., Zhang, Yi, Aleman-Muench, German R., Lewis, Gavin, Chen, Weixuan, Kang, Sarah, Luevanos, Melissa, Trudler, Dorit, Lipton, Stuart A., Soroosh, Pejman, Teijaro, John, de la Torre, Juan Carlos, Arditi, Moshe, Karin, Michael, Sanchez-Lopez, Elsa
Published in Immunity (Cambridge, Mass.) (13.07.2021)
Published in Immunity (Cambridge, Mass.) (13.07.2021)
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Journal Article
Immunological Consequences of Intestinal Fungal Dysbiosis
Wheeler, Matthew L., Limon, Jose J., Bar, Agnieszka S., Leal, Christian A., Gargus, Matthew, Tang, Jie, Brown, Jordan, Funari, Vincent A., Wang, Hanlin L., Crother, Timothy R., Arditi, Moshe, Underhill, David M., Iliev, Iliyan D.
Published in Cell host & microbe (08.06.2016)
Published in Cell host & microbe (08.06.2016)
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Journal Article
Ogg1-Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents Atherosclerosis
Tumurkhuu, Gantsetseg, Shimada, Kenichi, Dagvadorj, Jargalsaikhan, Crother, Timothy R, Zhang, Wenxuan, Luthringer, Daniel, Gottlieb, Roberta A, Chen, Shuang, Arditi, Moshe
Published in Circulation research (02.09.2016)
Published in Circulation research (02.09.2016)
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Journal Article
Expansion of commensal fungus Wallemia mellicola in the gastrointestinal mycobiota enhances the severity of allergic airway disease in mice
Skalski, Joseph H, Limon, Jose J, Sharma, Purnima, Gargus, Matthew D, Nguyen, Christopher, Tang, Jie, Coelho, Ana Lucia, Hogaboam, Cory M, Crother, Timothy R, Underhill, David M
Published in PLoS pathogens (20.09.2018)
Published in PLoS pathogens (20.09.2018)
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Journal Article
Lipopolysaccharide Induces Alveolar Macrophage Necrosis via CD14 and the P2X7 Receptor Leading to Interleukin-1α Release
Dagvadorj, Jargalsaikhan, Shimada, Kenichi, Chen, Shuang, Jones, Heather D., Tumurkhuu, Gantsetseg, Zhang, Wenxuan, Wawrowsky, Kolja A., Crother, Timothy R., Arditi, Moshe
Published in Immunity (Cambridge, Mass.) (21.04.2015)
Published in Immunity (Cambridge, Mass.) (21.04.2015)
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Journal Article
Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation
Noval Rivas, Magali, Wakita, Daiko, Franklin, Michael K., Carvalho, Thacyana T., Abolhesn, Amanda, Gomez, Angela C., Fishbein, Michael C., Chen, Shuang, Lehman, Thomas J., Sato, Kazuki, Shibuya, Akira, Fasano, Alessio, Kiyono, Hiroshi, Abe, Masanori, Tatsumoto, Narihito, Yamashita, Michifumi, Crother, Timothy R., Shimada, Kenichi, Arditi, Moshe
Published in Immunity (Cambridge, Mass.) (17.09.2019)
Published in Immunity (Cambridge, Mass.) (17.09.2019)
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Journal Article
NLRP3 Inflammasome Mediates Immune-Stromal Interactions in Vasculitis
Porritt, Rebecca A, Zemmour, David, Abe, Masanori, Lee, Youngho, Narayanan, Meena, Carvalho, Thacyana T, Gomez, Angela C, Martinon, Daisy, Santiskulvong, Chintda, Fishbein, Michael C, Chen, Shuang, Crother, Timothy R, Shimada, Kenichi, Arditi, Moshe, Noval Rivas, Magali
Published in Circulation research (15.10.2021)
Published in Circulation research (15.10.2021)
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Journal Article
Loss of testosterone impairs anti-tumor neutrophil function
Markman, Janet L., Porritt, Rebecca A., Wakita, Daiko, Lane, Malcolm E., Martinon, Daisy, Noval Rivas, Magali, Luu, Michael, Posadas, Edwin M., Crother, Timothy R., Arditi, Moshe
Published in Nature communications (31.03.2020)
Published in Nature communications (31.03.2020)
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Autophagy Protects Against Developing Increased Lung Permeability and Hypoxemia by Down Regulating Inflammasome Activity and IL-1β in LPS Plus Mechanical Ventilation-Induced Acute Lung Injury
Nosaka, Nobuyuki, Martinon, Daisy, Moreira, Debbie, Crother, Timothy R, Arditi, Moshe, Shimada, Kenichi
Published in Frontiers in immunology (14.02.2020)
Published in Frontiers in immunology (14.02.2020)
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Journal Article
Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer
Lowe, Emily L, Crother, Timothy R, Rabizadeh, Shervin, Hu, Bing, Wang, Hanlin, Chen, Shuang, Shimada, Kenichi, Wong, Michelle H, Michelsen, Kathrin S, Arditi, Moshe
Published in PloS one (27.09.2010)
Published in PloS one (27.09.2010)
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Journal Article
The NLRP3 inflammasome is required for the development of hypoxemia in LPS/mechanical ventilation acute lung injury
Jones, Heather D, Crother, Timothy R, Gonzalez-Villalobos, Romer A, Jupelli, Madhulika, Chen, Shuang, Dagvadorj, Jargalsaikhan, Arditi, Moshe, Shimada, Kenichi
Published in American journal of respiratory cell and molecular biology (01.02.2014)
Published in American journal of respiratory cell and molecular biology (01.02.2014)
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Journal Article
Role of Interleukin-1 Signaling in a Mouse Model of Kawasaki Disease–Associated Abdominal Aortic Aneurysm
Wakita, Daiko, Kurashima, Yosuke, Crother, Timothy R, Noval Rivas, Magali, Lee, Youngho, Chen, Shuang, Fury, Wen, Bai, Yu, Wagner, Shawn, Li, Debiao, Lehman, Thomas, Fishbein, Michael C, Hoffman, Hal M, Shah, Prediman K, Shimada, Kenichi, Arditi, Moshe
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2016)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2016)
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Journal Article
Chlamydia pneumoniae in Alzheimer's disease pathology
Subedi, Lalita, Gaire, Bhakta Prasad, Koronyo, Yosef, Koronyo-Hamaoui, Maya, Crother, Timothy R
Published in Frontiers in neuroscience (06.05.2024)
Published in Frontiers in neuroscience (06.05.2024)
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Journal Article
Mitochondrial quality control in health and cardiovascular diseases
Atici, Asli E., Crother, Timothy R., Noval Rivas, Magali
Published in Frontiers in cell and developmental biology (06.11.2023)
Published in Frontiers in cell and developmental biology (06.11.2023)
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Journal Article
IL-17A is proatherogenic in high-fat diet-induced and Chlamydia pneumoniae infection-accelerated atherosclerosis in mice
Chen, Shuang, Shimada, Kenichi, Zhang, Wenxuan, Huang, Ganghua, Crother, Timothy R, Arditi, Moshe
Published in The Journal of immunology (1950) (01.11.2010)
Published in The Journal of immunology (1950) (01.11.2010)
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Journal Article
Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model
Tumurkhuu, Gantsetseg, Chen, Shuang, Montano, Erica N, Ercan Laguna, Duygu, De Los Santos, Gabriela, Yu, Jeong Min, Lane, Malcolm, Yamashita, Michifumi, Markman, Janet L, Blanco, Luz P, Kaplan, Mariana J, Shimada, Kenichi, Crother, Timothy R, Ishimori, Mariko, Wallace, Daniel J, Jefferies, Caroline A, Arditi, Moshe
Published in Frontiers in immunology (24.09.2020)
Published in Frontiers in immunology (24.09.2020)
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Journal Article
Chlamydia pneumoniae infection in mice induces chronic lung inflammation, iBALT formation, and fibrosis
Jupelli, Madhulika, Shimada, Kenichi, Chiba, Norika, Slepenkin, Anatoly, Alsabeh, Randa, Jones, Heather D, Peterson, Ellena, Chen, Shuang, Arditi, Moshe, Crother, Timothy R
Published in PloS one (25.10.2013)
Published in PloS one (25.10.2013)
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Journal Article
Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection
Shimada, Kenichi, Crother, Timothy R, Karlin, Justin, Chen, Shuang, Chiba, Norika, Ramanujan, V Krishnan, Vergnes, Laurent, Ojcius, David M, Arditi, Moshe
Published in PloS one (2011)
Published in PloS one (2011)
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