Persistent Activation of NF-κB in BRCA1-Deficient Mammary Progenitors Drives Aberrant Proliferation and Accumulation of DNA Damage
Sau, Andrea, Lau, Rosanna, Cabrita, Miguel A., Nolan, Emma, Crooks, Peter A., Visvader, Jane E., Pratt, M.A. Christine
Published in Cell stem cell (07.07.2016)
Published in Cell stem cell (07.07.2016)
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Synthesis and anti-proliferative activity of aromatic substituted 5-((1-benzyl-1H-indol-3-yl)methylene)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione analogs against human tumor cell lines
Madadi, Nikhil Reddy, Penthala, Narsimha Reddy, Janganati, Venumadhav, Crooks, Peter A.
Published in Bioorganic & medicinal chemistry letters (15.01.2014)
Published in Bioorganic & medicinal chemistry letters (15.01.2014)
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One-pot multicomponent synthesis of indole incorporated thiazolylcoumarins and their antibacterial, anticancer and DNA cleavage studies
Gali, Rajitha, Banothu, Janardhan, Gondru, Ramesh, Bavantula, Rajitha, Velivela, Yashodhara, Crooks, Peter A.
Published in Bioorganic & medicinal chemistry letters (01.01.2015)
Published in Bioorganic & medicinal chemistry letters (01.01.2015)
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A novel tetrazole analogue of resveratrol is a potent anticancer agent
Bommagani, Shobanbabu, Penthala, Narsimha Reddy, Balasubramaniam, Meenakshisundaram, Kuravi, Sudhakiranmayi, Caldas-Lopes, Eloisi, Guzman, Monica L., Balusu, Ramesh, Crooks, Peter A.
Published in Bioorganic & medicinal chemistry letters (15.01.2019)
Published in Bioorganic & medicinal chemistry letters (15.01.2019)
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Racial Differences in Estimated GFR Decline, ESRD, and Mortality in an Integrated Health System
Derose, Stephen F., MD, MS, Rutkowski, Mark P., MD, Crooks, Peter W., MD, Shi, Jiaxiao M., PhD, Wang, Jean Q., MS, Kalantar-Zadeh, Kamyar, MD, MPH, PhD, Kovesdy, Csaba P., MD, Levin, Nathan W., MD, Jacobsen, Steven J., MD, PhD
Published in American journal of kidney diseases (01.08.2013)
Published in American journal of kidney diseases (01.08.2013)
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Targeting Aberrant Glutathione Metabolism to Eradicate Human Acute Myelogenous Leukemia Cells
Pei, Shanshan, Minhajuddin, Mohammad, Callahan, Kevin P., Balys, Marlene, Ashton, John M., Neering, Sarah J., Lagadinou, Eleni D., Corbett, Cheryl, Ye, Haobin, Liesveld, Jane L., O'Dwyer, Kristen M., Li, Zheng, Shi, Lei, Greninger, Patricia, Settleman, Jeffrey, Benes, Cyril, Hagen, Fred K., Munger, Joshua, Crooks, Peter A., Becker, Michael W., Jordan, Craig T.
Published in The Journal of biological chemistry (22.11.2013)
Published in The Journal of biological chemistry (22.11.2013)
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MMB triazole analogs are potent NF-κB inhibitors and anti-cancer agents against both hematological and solid tumor cells
Janganati, Venumadhav, Ponder, Jessica, Balasubramaniam, Meenakshisundaram, Bhat-Nakshatri, Poornima, Bar, Eli E., Nakshatri, Harikrishna, Jordan, Craig T., Crooks, Peter A.
Published in European journal of medicinal chemistry (05.09.2018)
Published in European journal of medicinal chemistry (05.09.2018)
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Actinomycin‐D and dimethylamino‐parthenolide synergism in treating human pancreatic cancer cells
Lamture, Gauri, Crooks, Peter A., Borrelli, Michael J.
Published in Drug development research (01.09.2018)
Published in Drug development research (01.09.2018)
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Vesicular monoamine transporter-2 inhibitor JPC-141 prevents methamphetamine-induced dopamine toxicity and blocks methamphetamine self-administration in rats
Chandler, Cassie M., Nickell, Justin R., George Wilson, A., Culver, John P., Crooks, Peter A., Bardo, Michael T., Dwoskin, Linda P.
Published in Biochemical pharmacology (01.10.2024)
Published in Biochemical pharmacology (01.10.2024)
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Synthesis and biological evaluation of novel 4,5-disubstituted 2H-1,2,3-triazoles as cis-constrained analogues of combretastatin A-4
Madadi, Nikhil R., Penthala, Narsimha R., Howk, Kevin, Ketkar, Amit, Eoff, Robert L., Borrelli, Michael J., Crooks, Peter A.
Published in European journal of medicinal chemistry (20.10.2015)
Published in European journal of medicinal chemistry (20.10.2015)
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Design and Synthesis of Novel Hybrid 8-Hydroxy Quinoline-Indole Derivatives as Inhibitors of Aβ Self-Aggregation and Metal Chelation-Induced Aβ Aggregation
Bowroju, Suresh K, Mainali, Nirjal, Ayyadevara, Srinivas, Penthala, Narsimha R, Krishnamachari, Sesha, Kakraba, Samuel, Shmookler Reis, Robert J, Crooks, Peter A
Published in Molecules (Basel, Switzerland) (08.08.2020)
Published in Molecules (Basel, Switzerland) (08.08.2020)
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Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion
Darrigues, Emilie, Zhao, Edward H, De Loose, Annick, Lee, Madison P, Borrelli, Michael J, Eoff, Robert L, Galileo, Deni S, Penthala, Narsimha R, Crooks, Peter A, Rodriguez, Analiz
Published in International journal of molecular sciences (03.10.2021)
Published in International journal of molecular sciences (03.10.2021)
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Deuteration of the farnesyl terminal methyl groups of δ-tocotrienol and its effects on the metabolic stability and ability of inducing G-CSF production
Liu, Xingui, Gao, Zhengya, Fu, Qiang, Song, Lin, Zhang, Peiyi, Zhang, Xuan, Hendrickson, Howard, Crooks, Peter A., Zhou, Daohong, Zheng, Guangrong
Published in Bioorganic & medicinal chemistry (01.06.2020)
Published in Bioorganic & medicinal chemistry (01.06.2020)
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Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer’s disease
Bowroju, Suresh K., Penthala, Narsimha R., Lakkaniga, Naga Rajiv, Balasubramaniam, Meenakshisundaram, Ayyadevara, Srinivas, Shmookler Reis, Robert J., Crooks, Peter A.
Published in Bioorganic & medicinal chemistry (01.09.2021)
Published in Bioorganic & medicinal chemistry (01.09.2021)
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Succinamide derivatives of melampomagnolide B and their anti-cancer activities
Janganati, Venumadhav, Ponder, Jessica, Thakkar, Shraddha, Jordan, Craig T., Crooks, Peter A.
Published in Bioorganic & medicinal chemistry (15.07.2017)
Published in Bioorganic & medicinal chemistry (15.07.2017)
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Antitumor properties of novel sesquiterpene lactone analogs as NFκB inhibitors that bind to the IKKβ ubiquitin-like domain (ULD)
Penthala, Narsimha R., Balasubramaniam, Meenakshisundaram, Dachavaram, Soma Shekar, Morris, Earl J., Bhat-Nakshatri, Poornima, Ponder, Jessica, Jordan, Craig T., Nakshatri, Harikrishna, Crooks, Peter A.
Published in European journal of medicinal chemistry (15.11.2021)
Published in European journal of medicinal chemistry (15.11.2021)
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Structural modeling of GSK3β implicates the inactive (DFG-out) conformation as the target bound by TDZD analogs
Balasubramaniam, Meenakshisundaram, Mainali, Nirjal, Bowroju, Suresh Kuarm, Atluri, Paavan, Penthala, Narsimha Reddy, Ayyadevera, Srinivas, Crooks, Peter A., Shmookler Reis, Robert J.
Published in Scientific reports (27.10.2020)
Published in Scientific reports (27.10.2020)
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