Bioprinted 3D Primary Liver Tissues Allow Assessment of Organ-Level Response to Clinical Drug Induced Toxicity In Vitro
Nguyen, Deborah G, Funk, Juergen, Robbins, Justin B, Crogan-Grundy, Candace, Presnell, Sharon C, Singer, Thomas, Roth, Adrian B
Published in PloS one (07.07.2016)
Published in PloS one (07.07.2016)
Get full text
Journal Article
Discovery of 4-Aryl-4H-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-Based High Throughput Screening Assay. 4. Structure–Activity Relationships of N-Alkyl Substituted Pyrrole Fused at the 7,8-Positions
Kemnitzer, William, Drewe, John, Jiang, Songchun, Zhang, Hong, Crogan-Grundy, Candace, Labreque, Denis, Bubenick, Monica, Attardo, Giorgio, Denis, Real, Lamothe, Serge, Gourdeau, Henriette, Tseng, Ben, Kasibhatla, Shailaja, Cai, Sui Xiong
Published in Journal of medicinal chemistry (14.02.2008)
Published in Journal of medicinal chemistry (14.02.2008)
Get full text
Journal Article
Discovery and Structure−Activity Relationship of 3-Aryl-5-aryl-1,2,4-oxadiazoles as a New Series of Apoptosis Inducers and Potential Anticancer Agents
Zhang, Han-Zhong, Kasibhatla, Shailaja, Kuemmerle, Jared, Kemnitzer, William, Ollis-Mason, Kristin, Qiu, Ling, Crogan-Grundy, Candace, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Journal of medicinal chemistry (11.08.2005)
Published in Journal of medicinal chemistry (11.08.2005)
Get full text
Journal Article
Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 7- and 5-, 6-, 8-positions
KEMNITZER, William, KASIBHATLA, Shailaja, VAILLANCOURT, Louis, CHARRON, Sylvie, DODD, Jennifer, ATTARDO, Giorgio, LABRECQUE, Denis, LAMOTHE, Serge, GOURDEAU, Henriette, TSENG, Ben, DREWE, John, SUI XIONG CAI, SONGCHUN JIANG, HONG ZHANG, JIANGHONG ZHAO, SHAOJUAN JIA, LIFEN XU, CROGAN-GRUNDY, Candace, DENIS, Réal, BARRIAULT, Nancy
Published in Bioorganic & medicinal chemistry letters (01.11.2005)
Published in Bioorganic & medicinal chemistry letters (01.11.2005)
Get full text
Journal Article
Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell-and caspase-based HTS assay. Part 5: Modifications of the 2-and 3-positions
KEMNITZER, William, SONGCHUN JIANG, GOURDEAU, Henriette, TSENG, Ben, DREWE, John, SUI XIONG CAI, YAN WANG, KASIBHATLA, Shailaja, CROGAN-GRUNDY, Candace, BUBENIK, Monica, LABRECQUE, Denis, DENIS, Real, LAMOTHE, Serge, ATTARDO, Giorgio
Published in Bioorganic & medicinal chemistry (15.01.2008)
Published in Bioorganic & medicinal chemistry (15.01.2008)
Get full text
Journal Article
Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell-and caspase-based high-throughput screening assay. Part 1: Structure-activity relationships of the 1-and 3-positions
KEMNITZER, William, KUEMMERLE, Jared, SONGCHUN JIANG, ZHANG, Han-Zhong, SIRISOMA, Nilantha, KASIBHATLA, Shailaja, CROGAN-GRUNDY, Candace, TSENG, Ben, DREWE, John, SUI XIONG CAI
Published in Bioorganic & medicinal chemistry letters (01.12.2008)
Published in Bioorganic & medicinal chemistry letters (01.12.2008)
Get full text
Journal Article
Selective activation of apoptosis by a novel set of 4-aryl-3-(3-aryl-1-oxo-2-propenyl)-2( 1H )-quinolinones through a Myc-dependent pathway
Claassen, Gisela, Brin, Elena, Crogan-Grundy, Candace, Vaillancourt, Mei Ting, Zhang, Han Zhong, Cai, Sui Xiong, Drewe, John, Tseng, Ben, Kasibhatla, Shailaja
Published in Cancer letters (18.02.2009)
Published in Cancer letters (18.02.2009)
Get full text
Journal Article
Discovery of 4-Aryl-4H-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-Based High-Throughput Screening Assay. 3. Structure−Activity Relationships of Fused Rings at the 7,8-Positions
Kemnitzer, William, Drewe, John, Jiang, Songchun, Zhang, Hong, Zhao, Jianghong, Crogan-Grundy, Candace, Xu, Lifen, Lamothe, Serge, Gourdeau, Henriette, Denis, Réal, Tseng, Ben, Kasibhatla, Shailaja, Cai, Sui Xiong
Published in Journal of medicinal chemistry (14.06.2007)
Published in Journal of medicinal chemistry (14.06.2007)
Get full text
Journal Article
Discovery of 1-benzoyl-3-cyanopyrrolo[1,2- a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2: Structure–activity relationships of the 4-, 5-, 6-, 7- and 8-positions
Kemnitzer, William, Kuemmerle, Jared, Jiang, Songchun, Sirisoma, Nilantha, Kasibhatla, Shailaja, Crogan-Grundy, Candace, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry letters (01.07.2009)
Published in Bioorganic & medicinal chemistry letters (01.07.2009)
Get full text
Journal Article
Discovery of 4-aryl-2-oxo-2H-chromenes as a new series of apoptosis inducers using a cell-and caspase-based high-throughput screening assay
KEMNITZER, William, SONGCHUN JIANG, TSENG, Ben, DREWE, John, SUI XIONG CAI, HONG ZHANG, KASIBHATLA, Shailaja, CROGAN-GRUNDY, Candace, BLAIS, Charles, ATTARDO, Giorgio, DENIS, Real, LAMOTHE, Serge, GOURDEAU, Henriette
Published in Bioorganic & medicinal chemistry letters (15.10.2008)
Published in Bioorganic & medicinal chemistry letters (15.10.2008)
Get full text
Journal Article
Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure–activity relationships of the carboxamide group
Kemnitzer, William, Sirisoma, Nilantha, Nguyen, Bao, Jiang, Songchun, Kasibhatla, Shailaja, Crogan-Grundy, Candace, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry letters (01.06.2009)
Published in Bioorganic & medicinal chemistry letters (01.06.2009)
Get full text
Journal Article
Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 9-oxo-9H-fluorene ring
KEMNITZER, William, SIRISOMA, Nilantha, SONGCHUN JIANG, KASIBHATLA, Shailaja, CROGAN-GRUNDY, Candace, TSENG, Ben, DREWE, John, SUI XIONG CAI
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Get full text
Journal Article
Discovery of (naphthalen-4-yl)(phenyl)methanones and N-methyl- N-phenylnaphthalen-1-amines as new apoptosis inducers using a cell- and caspase-based HTS assay
Jiang, Songchun, Crogan-Grundy, Candace, Drewe, John, Tseng, Ben, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry (01.11.2008)
Published in Bioorganic & medicinal chemistry (01.11.2008)
Get full text
Journal Article
Discovery and structure–activity relationships of (2-(arylthio)benzylideneamino)guanidines as a novel series of potent apoptosis inducers
Zhang, Han-Zhong, Crogan-Grundy, Candace, May, Chris, Drewe, John, Tseng, Ben, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry (01.04.2009)
Published in Bioorganic & medicinal chemistry (01.04.2009)
Get full text
Journal Article
Discovery of substituted 4-anilino-2-arylpyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 2. Structure–activity relationships of the 2-aryl group
Sirisoma, Nilantha, Pervin, Azra, Nguyen, Bao, Crogan-Grundy, Candace, Kasibhatla, Shailaja, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry letters (15.04.2009)
Published in Bioorganic & medicinal chemistry letters (15.04.2009)
Get full text
Journal Article
Discovery of N-aryl-9-oxo-9 H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure–activity relationships of the 9-oxo-9 H-fluorene ring
Kemnitzer, William, Sirisoma, Nilantha, Jiang, Songchun, Kasibhatla, Shailaja, Crogan-Grundy, Candace, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
Get full text
Journal Article
Erratum to “Discovery of 4-aryl-2-oxo-2H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay” [Bioorg. Med. Chem. Lett. 18 (2008) 5571–5575]
Kemnitzer, William, Jiang, Songchun, Zhang, Hong, Kasibhatla, Shailaja, Crogan-Grundy, Candace, Blais, Charles, Attardo, Giorgio, Denis, Real, Lamothe, Serge, Gourdeau, Henriette, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry letters (2009)
Published in Bioorganic & medicinal chemistry letters (2009)
Get full text
Journal Article
Discovery of 4-Aryl-4 H -chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-Based High-Throughput Screening Assay. 3. Structure−Activity Relationships of Fused Rings at the 7,8-Positions
Kemnitzer, William, Drewe, John, Jiang, Songchun, Zhang, Hong, Zhao, Jianghong, Crogan-Grundy, Candace, Xu, Lifen, Lamothe, Serge, Gourdeau, Henriette, Denis, Réal, Tseng, Ben, Kasibhatla, Shailaja, Cai, Sui Xiong
Published in Journal of medicinal chemistry (01.06.2007)
Published in Journal of medicinal chemistry (01.06.2007)
Get full text
Journal Article
Discovery of 4-aryl-2-oxo-2 H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay
Kemnitzer, William, Jiang, Songchun, Zhang, Hong, Kasibhatla, Shailaja, Crogan-Grundy, Candace, Blais, Charles, Attardo, Giorgio, Denis, Real, Lamothe, Serge, Gourdeau, Henriette, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry letters (2008)
Published in Bioorganic & medicinal chemistry letters (2008)
Get full text
Journal Article