Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape
Bartz, René, Fan, Haihong, Zhang, Jingtao, Innocent, Nathalie, Cherrin, Craig, Beck, Stephen C, Pei, Yi, Momose, Aaron, Jadhav, Vasant, Tellers, David M, Meng, Fanyu, Crocker, Louis S, Sepp-Lorenzino, Laura, Barnett, Stanley F
Published in Biochemical journal (15.04.2011)
Published in Biochemical journal (15.04.2011)
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Ionization Behavior of Amino Lipids for siRNA Delivery: Determination of Ionization Constants, SAR, and the Impact of Lipid pK a on Cationic Lipid−Biomembrane Interactions
Zhang, Jingtao, Fan, Haihong, Levorse, Dorothy A, Crocker, Louis S
Published in Langmuir (01.03.2011)
Published in Langmuir (01.03.2011)
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Journal Article
Physicochemical and Formulation Developability Assessment for Therapeutic Peptide Delivery—A Primer
Bak, Annette, Leung, Dennis, Barrett, Stephanie E., Forster, Seth, Minnihan, Ellen C., Leithead, Andrew W., Cunningham, James, Toussaint, Nathalie, Crocker, Louis S.
Published in The AAPS journal (01.01.2015)
Published in The AAPS journal (01.01.2015)
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Interaction of Cholesterol-Conjugated Ionizable Amino Lipids with Biomembranes: Lipid Polymorphism, Structure–Activity Relationship, and Implications for siRNA Delivery
Zhang, Jingtao, Fan, Haihong, Levorse, Dorothy A, Crocker, Louis S
Published in Langmuir (02.08.2011)
Published in Langmuir (02.08.2011)
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Assessing Mixing Quality of a Copovidone-TPGS Hot Melt Extrusion Process with Atomic Force Microscopy and Differential Scanning Calorimetry
Lamm, Matthew S., DiNunzio, James, Khawaja, Nazia N., Crocker, Louis S., Pecora, Anthony
Published in AAPS PharmSciTech (01.02.2016)
Published in AAPS PharmSciTech (01.02.2016)
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Endosomolytic Bioreducible Poly(amido amine disulfide) Polymer Conjugates for the in Vivo Systemic Delivery of siRNA Therapeutics
Parmar, Rubina Giare, Busuek, Marina, Walsh, Eileen S, Leander, Karen R, Howell, Bonnie J, Sepp-Lorenzino, Laura, Kemp, Eric, Crocker, Louis S, Leone, Anthony, Kochansky, Christopher J, Carr, Brian A, Garbaccio, Robert M, Colletti, Steven L, Wang, Weimin
Published in Bioconjugate chemistry (17.04.2013)
Published in Bioconjugate chemistry (17.04.2013)
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Development of a liver-targeted siRNA delivery platform with a broad therapeutic window utilizing biodegradable polypeptide-based polymer conjugates
Barrett, Stephanie E., Burke, Rob S., Abrams, Marc T., Bason, Carol, Busuek, Marina, Carlini, Edward, Carr, Brian A., Crocker, Louis S., Fan, Haihong, Garbaccio, Robert M., Guidry, Erin N., Heo, Jun H., Howell, Bonnie J., Kemp, Eric A., Kowtoniuk, Robert A., Latham, Andrew H., Leone, Anthony M., Lyman, Michael, Parmar, Rubina G., Patel, Mihir, Pechenov, Sergey Y., Pei, Tao, Pudvah, Nicole T., Raab, Conrad, Riley, Sean, Sepp-Lorenzino, Laura, Smith, Sheri, Soli, Eric D., Staskiewicz, Steven, Stern, Melissa, Truong, Quang, Vavrek, Marissa, Waldman, Jacob H., Walsh, Eileen S., Williams, J. Michael, Young, Stephanie, Colletti, Steven L.
Published in Journal of controlled release (10.06.2014)
Published in Journal of controlled release (10.06.2014)
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An in vivo evaluation of amphiphilic, biodegradable peptide copolymers as siRNA delivery agents
Barrett, Stephanie E., Abrams, Marc T., Burke, Rob, Carr, Brian A., Crocker, Louis S., Garbaccio, Robert M., Howell, Bonnie J., Kemp, Eric A., Kowtoniuk, Robert A., Latham, Andrew H., Leander, Karen R., Leone, Anthony M., Patel, Mihir, Pechenov, Sergey, Pudvah, Nicole T., Riley, Sean, Sepp-Lorenzino, Laura, Walsh, Eileen S., Williams, J. Michael, Colletti, Steven L.
Published in International journal of pharmaceutics (15.05.2014)
Published in International journal of pharmaceutics (15.05.2014)
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An Etoricoxib Phase Diagram: Hemihydrate and Anhydrate
Crocker, Louis S, Ge, Zhihong, Abrahim, Ahmed, Hartman, Robert, Xu, Jing
Published in Organic process research & development (01.11.2003)
Published in Organic process research & development (01.11.2003)
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Development and Validation of an HPLC Method for the Impurity and Quantitative Analysis of Etoricoxib
Hartman, Robert, Abrahim, Ahmed, Clausen, Andrew, Mao, Bing, Crocker, Louis S., Ge, Zhihong
Published in Journal of liquid chromatography & related technologies (01.08.2003)
Published in Journal of liquid chromatography & related technologies (01.08.2003)
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Journal Article
Ionization Behavior of Amino Lipids for siRNA Delivery: Determination of Ionization Constants, SAR, and the Impact of Lipid p K a on Cationic Lipid−Biomembrane Interactions
Zhang, Jingtao, Fan, Haihong, Levorse, Dorothy A., Crocker, Louis S.
Published in Langmuir (01.03.2011)
Published in Langmuir (01.03.2011)
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Journal Article
Ultrasonic particle size reduction of radiolabeled pharmaceuticals
Schenk, David J., Jones, Allen N., Braun, Matthew P., Yao, Dan, Wallace, Michael A., Marques, Rosemary, Jenkins, Herbert J., Chang, Anson, Jia, Xiujuan, Crocker, Louis S., Dean, Dennis C., Melillo, David G.
Published in Journal of labelled compounds & radiopharmaceuticals (01.06.2004)
Published in Journal of labelled compounds & radiopharmaceuticals (01.06.2004)
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